Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: HOOK1 (spascer ID:51361)

Gene summary for HOOK1

Gene summary

Gene information
	Species	Human
	Gene symbol	HOOK1
	Gene ID	51361
	Gene name	hook microtubule tethering protein 1
	Synonyms	HK1
	Cytomap	1p32.1
	Type of gene	protein-coding
	Description	protein Hook homolog 1h-hook1hHK1hook homolog 1
	Modification date	20220513
	UniProtAcc	Q9UJC3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
HOOK1	GO:0005737	cytoplasm	21873635	Component
HOOK1	GO:0005813	centrosome	21873635	Component
HOOK1	GO:0008017	microtubule binding	21873635	Function
HOOK1	GO:0030705	cytoskeleton-dependent intracellular transport	21873635	Process
HOOK1	GO:0031122	cytoplasmic microtubule organization	21873635	Process
HOOK1	GO:0051959	dynein light intermediate chain binding	21873635	Function

Top

Spatial pattern events for HOOK1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
HOOK1	Human	Liver	rep_liver1	34417225	2.11e-14
HOOK1	Human	Liver	rep_liver2	34417225	6.98e-16
HOOK1	Human	Lung	rep_1	35355018	1.37e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Lung_rep_1_H&E

Top

Spatial pattern pathway has HOOK1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
HOOK1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Human	Intestine	A3	2.5e-12
HOOK1	GOBP_Cytosolic_Transport	Human	Intestine	A3	5.9e-09
HOOK1	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Intestine	A3	2.7e-15
HOOK1	GOBP_Endomembrane_System_Organization	Human	Intestine	A3	1.6e-16
HOOK1	GOBP_Endosome_To_Lysosome_Transport	Human	Intestine	A3	2.6e-09
HOOK1	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
HOOK1	GOBP_Gamete_Generation	Human	Intestine	A3	4.2e-13
HOOK1	GOBP_Germ_Cell_Development	Human	Intestine	A3	1.9e-07
HOOK1	GOBP_Golgi_Organization	Human	Intestine	A3	2.9e-07
HOOK1	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
HOOK1	GOBP_Lysosomal_Transport	Human	Intestine	A3	7.2e-12
HOOK1	GOBP_Male_Gamete_Generation	Human	Intestine	A3	4.8e-15
HOOK1	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
HOOK1	GOBP_Microtubule_Cytoskeleton_Organization	Human	Intestine	A3	4.8e-11
HOOK1	GOBP_Multicellular_Organism_Reproduction	Human	Intestine	A3	4.1e-15
HOOK1	GOBP_Reproduction	Human	Intestine	A3	4.6e-19
HOOK1	GOBP_Spermatid_Differentiation	Human	Intestine	A3	4.3e-09
HOOK1	GOBP_Vacuolar_Transport	Human	Intestine	A3	4.3e-14
HOOK1	GOBP_Vesicle_Organization	Human	Intestine	A3	3.0e-15
HOOK1	GOBP_Endosome_Organization	Human	Intestine	A8	1.9e-13
HOOK1	GOBP_Lytic_Vacuole_Organization	Human	Intestine	A8	2.3e-16
HOOK1	GOBP_Vacuole_Organization	Human	Intestine	A8	2.4e-07
HOOK1	GOBP_Endosome_To_Lysosome_Transport	Human	Pancreas	PDAC-B-st1	4.8e-06
HOOK1	GOBP_Golgi_Organization	Human	Pancreas	PDAC-B-st1	7.2e-05
HOOK1	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Uterus	rep_1	1.6e-06
HOOK1	GOBP_Vesicle_Mediated_Transport_Between_Endosomal_Compartments	Human	Uterus	rep_1	4.0e-06
HOOK1	GOBP_Endosome_To_Lysosome_Transport	Human	Uterus	rep_25	2.2e-06
HOOK1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Human	Uterus	rep_26	6.1e-12
HOOK1	GOBP_Cytoplasmic_Microtubule_Organization	Human	Uterus	rep_26	7.5e-09
HOOK1	GOBP_Endosome_Organization	Human	Uterus	rep_26	5.1e-07
HOOK1	GOBP_Gamete_Generation	Human	Uterus	rep_26	3.8e-10
HOOK1	GOBP_Germ_Cell_Development	Human	Uterus	rep_26	1.1e-12
HOOK1	GOBP_Lysosomal_Transport	Human	Uterus	rep_26	1.3e-08
HOOK1	GOBP_Lytic_Vacuole_Organization	Human	Uterus	rep_26	2.4e-06
HOOK1	GOBP_Male_Gamete_Generation	Human	Uterus	rep_26	7.4e-14
HOOK1	GOBP_Spermatid_Differentiation	Human	Uterus	rep_26	1.7e-09
HOOK1	GOBP_Vacuolar_Transport	Human	Uterus	rep_26	2.2e-09
HOOK1	GOBP_Vacuole_Organization	Human	Uterus	rep_26	3.0e-12
HOOK1	GOBP_Cytoskeleton_Organization	Human	Breast	rep_1	1.3e-22
HOOK1	GOBP_Endomembrane_System_Organization	Human	Breast	rep_1	2.2e-04
HOOK1	GOBP_Endosome_To_Lysosome_Transport	Human	Breast	rep_1	1.9e-06
HOOK1	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
HOOK1	GOBP_Golgi_Organization	Human	Breast	rep_1	6.6e-40
HOOK1	GOBP_Lytic_Vacuole_Organization	Human	Breast	rep_1	1.4e-06
HOOK1	GOBP_Supramolecular_Fiber_Organization	Human	Breast	rep_1	2.8e-72
HOOK1	GOBP_Vacuole_Organization	Human	Breast	rep_1	6.9e-10
HOOK1	GOBP_Vesicle_Mediated_Transport_Between_Endosomal_Compartments	Human	Breast	rep_1	7.6e-85
HOOK1	GOBP_Vesicle_Organization	Human	Breast	rep_1	8.3e-15
HOOK1	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Breast	rep_5	1.5e-12
HOOK1	GOBP_Endosome_Organization	Human	Breast	rep_5	4.4e-04
HOOK1	GOBP_Lysosomal_Transport	Human	Breast	rep_5	9.9e-17
HOOK1	GOBP_Multicellular_Organism_Reproduction	Human	Breast	rep_5	8.1e-07
HOOK1	GOBP_Reproduction	Human	Breast	rep_5	8.1e-06
HOOK1	GOBP_Vacuolar_Transport	Human	Breast	rep_5	6.0e-13
HOOK1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Human	Breast	rep_6	4.4e-11
HOOK1	GOBP_Cytoplasmic_Microtubule_Organization	Human	Breast	rep_6	2.7e-05
HOOK1	GOBP_Cytosolic_Transport	Human	Breast	rep_6	2.6e-05
HOOK1	GOBP_Gamete_Generation	Human	Breast	rep_6	7.3e-08
HOOK1	GOBP_Germ_Cell_Development	Human	Breast	rep_6	6.2e-11
HOOK1	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
HOOK1	GOBP_Male_Gamete_Generation	Human	Breast	rep_6	4.3e-06
HOOK1	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
HOOK1	GOBP_Microtubule_Cytoskeleton_Organization	Human	Breast	rep_6	1.9e-04
HOOK1	GOBP_Spermatid_Differentiation	Human	Breast	rep_6	1.9e-07
HOOK1	GOBP_Cytoplasmic_Microtubule_Organization	Human	Skin	P5_rep1	3.9e-11
HOOK1	GOBP_Vesicle_Organization	Human	Skin	P5_rep1	2.3e-09
HOOK1	GOBP_Cytoskeleton_Organization	Human	Skin	P9_rep3	3.1e-12
HOOK1	GOBP_Lysosomal_Transport	Human	Lung	rep_2	4.5e-09
HOOK1	GOBP_Vacuolar_Transport	Human	Lung	rep_2	8.0e-08

Top

HOOK1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

HOOK1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for HOOK1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for HOOK1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for HOOK1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source