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Spatial pattern gene: CRNKL1 (spascer ID:51340) |
Gene summary for CRNKL1 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | CRNKL1 | Gene ID | 51340 |
| Gene name | crooked neck pre-mRNA splicing factor 1 |
| Synonyms | CLF|CRN|Clf1|HCRN|MSTP021|SYF3 |
| Cytomap | 20p11.23 |
| Type of gene | protein-coding |
| Description | crooked neck-like protein 1Crn, crooked neck-like 1SYF3 pre-mRNA-splicing factorcrooked neck homologcrooked neck pre-mRNA splicing factor-like 1crooked neck-like 1 |
| Modification date | 20220513 |
| UniProtAcc | Q9BZJ0 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| CRNKL1 | GO:0000245 | spliceosomal complex assembly | 21873635 | Process |
| CRNKL1 | GO:0000398 | mRNA splicing, via spliceosome | 21873635 | Process |
| CRNKL1 | GO:0000974 | Prp19 complex | 21873635 | Component |
| CRNKL1 | GO:0071007 | U2-type catalytic step 2 spliceosome | 21873635 | Component |
| CRNKL1 | GO:0071014 | post-mRNA release spliceosomal complex | 21873635 | Component |
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Spatial pattern events for CRNKL1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| CRNKL1 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| CRNKL1 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
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Spatial pattern pathway has CRNKL1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| CRNKL1 | GOBP_Mrna_Metabolic_Process | Human | Intestine | A3 | 7.7e-20 |
| CRNKL1 | GOBP_Mrna_Processing | Human | Intestine | A3 | 4.9e-17 |
| CRNKL1 | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Intestine | A3 | 1.6e-07 |
| CRNKL1 | GOBP_Rna_Processing | Human | Intestine | A3 | 3.9e-09 |
| CRNKL1 | GOBP_Rna_Splicing | Human | Intestine | A3 | 3.3e-19 |
| CRNKL1 | GOBP_Rna_Splicing_Via_Transesterification_Reactions | Human | Intestine | A3 | 2.2e-12 |
| CRNKL1 | GOBP_Spliceosomal_Complex_Assembly | Human | Intestine | A3 | 8.7e-10 |
| CRNKL1 | GOBP_Mrna_Metabolic_Process | Human | Pancreas | PDAC-B-st1 | 2.6e-05 |
| CRNKL1 | GOBP_Rna_Splicing | Human | Pancreas | PDAC-B-st1 | 1.9e-05 |
| CRNKL1 | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Uterus | rep_26 | 4.6e-06 |
| CRNKL1 | GOBP_Rna_Splicing | Human | Uterus | rep_26 | 1.0e-05 |
| CRNKL1 | GOBP_Spliceosomal_Complex_Assembly | Human | Uterus | rep_26 | 5.6e-09 |
| CRNKL1 | GOBP_Mrna_Metabolic_Process | Human | Breast | rep_6 | 3.0e-08 |
| CRNKL1 | GOBP_Mrna_Processing | Human | Breast | rep_6 | 1.5e-06 |
| CRNKL1 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Human | Breast | rep_6 | 1.3e-07 |
| CRNKL1 | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Breast | rep_6 | 1.4e-08 |
| CRNKL1 | GOBP_Rna_Processing | Human | Breast | rep_6 | 3.5e-06 |
| CRNKL1 | GOBP_Rna_Splicing | Human | Breast | rep_6 | 1.1e-09 |
| CRNKL1 | GOBP_Rna_Splicing_Via_Transesterification_Reactions | Human | Breast | rep_6 | 5.4e-08 |
| CRNKL1 | GOBP_Spliceosomal_Complex_Assembly | Human | Breast | rep_6 | 2.2e-12 |
| CRNKL1 | GOBP_Mrna_Metabolic_Process | Human | Skin | P5_rep3 | 1.8e-08 |
| CRNKL1 | GOBP_Mrna_Processing | Human | Skin | P5_rep3 | 9.7e-09 |
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CRNKL1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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CRNKL1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for CRNKL1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for CRNKL1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CRNKL1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
