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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: NGRN (spascer ID:51335)

Gene summary for NGRN

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

NGRN

Gene ID

51335

Gene nameneugrin, neurite outgrowth associated
SynonymsDSC92
Cytomap15q26.1
Type of geneprotein-coding
Descriptionneugrinmesenchymal stem cell protein DSC92neurite outgrowth associated proteinspinal cord-derived protein FI58G
Modification date20220513
UniProtAcc

Q9NPE2


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
NGRN

GO:0005634

nucleus

21873635

Component

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Spatial pattern events for NGRN

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
NGRNHumanBrainrep_10 335586955.75e-15
NGRNHumanIntestinerep_colon1 344172251.95e-15
NGRNHumanIntestinerep_colon2 344172258.12e-16
NGRNHumanIntestinerep_colon3 344172252.48e-06
NGRNHumanLiverrep_liver1 344172251.08e-15
NGRNHumanLiverrep_liver2 344172256.98e-16
NGRNHumanLiverrep_liver4 344172251.84e-13
NGRNHumanSkinP2_rep1 329467857.41e-11
NGRNHumanSkinP2_rep3 329467859.21e-15
NGRNHumanSkinP9_rep2 329467854.63e-07
NGRNHumanLungrep_1 353550183.42e-12

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_10_H&E
boxplot

boxplot
Intestine_rep_colon1_H&E
boxplot

boxplot
Intestine_rep_colon2_H&E
boxplot

boxplot
Intestine_rep_colon3_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Liver_rep_liver4_H&E
boxplot

boxplot
Skin_P2_rep3_H&E
boxplot

boxplot
Skin_P9_rep2_H&E
boxplot

boxplot
Lung_rep_1_H&E
boxplot

boxplot


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Spatial pattern pathway has NGRN envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
NGRNGOBP_NeurogenesisHumanBrainrep_1 7.4e-34
NGRNGOBP_Neuron_DifferentiationHumanBrainrep_1 7.4e-34
NGRNGOBP_Positive_Regulation_Of_Gene_ExpressionHumanBrainrep_1 4.4e-07
NGRNGOBP_Positive_Regulation_Of_Protein_Metabolic_ProcessHumanBrainrep_1 4.4e-07
NGRNGOBP_NeurogenesisHumanLiverrep_1 1.0e-70
NGRNGOBP_Neuron_DifferentiationHumanLiverrep_1 1.5e-73
NGRNGOBP_Positive_Regulation_Of_Gene_ExpressionHumanLiverrep_1 3.7e-85
NGRNGOBP_Positive_Regulation_Of_Protein_Metabolic_ProcessHumanLiverrep_1 1.1e-67
NGRNGOBP_Positive_Regulation_Of_Gene_ExpressionHumanIntestinerep_colon4 6.4e-48
NGRNGOBP_Positive_Regulation_Of_Protein_Metabolic_ProcessHumanIntestinerep_colon4 1.2e-51
NGRNGOBP_Amide_Biosynthetic_ProcessHumanIntestineA1 6.4e-07
NGRNGOBP_Peptide_Biosynthetic_ProcessHumanIntestineA1 4.6e-10
NGRNGOBP_Positive_Regulation_Of_TranslationHumanIntestineA1 7.9e-07
NGRNGOBP_NeurogenesisHumanIntestineA3 6.4e-14
NGRNGOBP_Neuron_DifferentiationHumanIntestineA3 1.4e-11
NGRNGOBP_Positive_Regulation_Of_Gene_ExpressionHumanIntestineA3 3.7e-11
NGRNGOBP_Positive_Regulation_Of_Protein_Metabolic_ProcessHumanIntestineA3 5.0e-14
NGRNGOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionHumanIntestineA3 4.2e-08
NGRNGOBP_Regulation_Of_Cellular_Amide_Metabolic_ProcessHumanIntestineA3 2.1e-07
NGRNGOBP_Mitochondrial_Gene_ExpressionHumanIntestineA8 1.4e-08
NGRNGOBP_Mitochondrial_TranslationHumanIntestineA8 1.7e-08
NGRNGOBP_Positive_Regulation_Of_Mitochondrial_TranslationHumanIntestineA8 7.5e-07
NGRNGOBP_Regulation_Of_Mitochondrial_Gene_ExpressionHumanIntestineA8 1.3e-15
NGRNGOBP_Mitochondrial_TranslationHumanPancreasPDAC-B-st1 5.1e-05
NGRNGOBP_Regulation_Of_Mitochondrial_Gene_ExpressionHumanPancreasPDAC-A-st2 6.0e-05
NGRNGOBP_Mitochondrial_TranslationHumanUterusrep_25 3.6e-06
NGRNGOBP_Positive_Regulation_Of_Mitochondrial_TranslationHumanUterusrep_25 1.8e-11
NGRNGOBP_Regulation_Of_Mitochondrial_Gene_ExpressionHumanUterusrep_25 1.8e-10
NGRNGOBP_Mitochondrial_Gene_ExpressionHumanUterusrep_26 1.3e-15
NGRNGOBP_NeurogenesisHumanBreastrep_1 8.0e-11
NGRNGOBP_Neuron_DifferentiationHumanBreastrep_1 1.1e-16
NGRNGOBP_Positive_Regulation_Of_Gene_ExpressionHumanBreastrep_1 7.3e-07
NGRNGOBP_Positive_Regulation_Of_Protein_Metabolic_ProcessHumanBreastrep_5 2.6e-04
NGRNGOBP_Amide_Biosynthetic_ProcessHumanBreastrep_6 8.7e-05
NGRNGOBP_Cellular_Amide_Metabolic_ProcessHumanBreastrep_6 5.6e-05
NGRNGOBP_Mitochondrial_Gene_ExpressionHumanBreastrep_6 9.9e-07
NGRNGOBP_Mitochondrial_TranslationHumanBreastrep_6 1.3e-06
NGRNGOBP_Organonitrogen_Compound_Biosynthetic_ProcessHumanBreastrep_6 1.2e-09
NGRNGOBP_Peptide_Biosynthetic_ProcessHumanBreastrep_6 1.6e-05
NGRNGOBP_Peptide_Metabolic_ProcessHumanBreastrep_6 8.7e-05
NGRNGOBP_Positive_Regulation_Of_TranslationHumanBreastrep_6 3.8e-04
NGRNGOBP_Regulation_Of_Mitochondrial_Gene_ExpressionHumanBreastrep_6 1.0e-05
NGRNGOBP_Regulation_Of_Mitochondrial_Gene_ExpressionHumanSkinP10_rep2 7.9e-11

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NGRN function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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NGRN function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for NGRN envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for NGRN

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NGRN

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource