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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ZDHHC3 (spascer ID:51304)

Gene summary for ZDHHC3

Gene summary

Gene information
	Species	Human
	Gene symbol	ZDHHC3
	Gene ID	51304
	Gene name	zinc finger DHHC-type palmitoyltransferase 3
	Synonyms	DHHC-3\|DHHC3\|GODZ\|ZNF373
	Cytomap	3p21.31
	Type of gene	protein-coding
	Description	palmitoyltransferase ZDHHC3DHHC1 proteinGolgi apparatus-specific protein with DHHC zinc finger domainacyltransferase ZDHHC3golgi-specific DHHC Zinc Finger Proteinzinc finger DHHC domain-containing protein 3zinc finger DHHC-type containing 3zinc fin
	Modification date	20220513
	UniProtAcc	Q9NYG2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ZDHHC3	GO:0005783	endoplasmic reticulum	21873635	Component
ZDHHC3	GO:0005794	Golgi apparatus	21873635	Component
ZDHHC3	GO:0006612	protein targeting to membrane	21873635	Process
ZDHHC3	GO:0018230	peptidyl-L-cysteine S-palmitoylation	21873635	Process
ZDHHC3	GO:0019706	protein-cysteine S-palmitoyltransferase activity	21873635	Function

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Spatial pattern events for ZDHHC3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ZDHHC3	Human	Intestine	rep_colon1	34417225	1.95e-15
ZDHHC3	Human	Intestine	rep_colon2	34417225	8.12e-16
ZDHHC3	Human	Intestine	rep_colon4	34417225	4.53e-07
ZDHHC3	Human	Liver	rep_liver1	34417225	1.08e-15
ZDHHC3	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has ZDHHC3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ZDHHC3	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Brain	rep_1	2.8e-23
ZDHHC3	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
ZDHHC3	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Brain	rep_1	2.8e-23
ZDHHC3	GOBP_Regulation_Of_Protein_Localization	Human	Brain	rep_4	1.0e-14
ZDHHC3	GOBP_Positive_Regulation_Of_Protein_Localization_To_Synapse	Human	Brain	st	9.9e-54
ZDHHC3	GOBP_Trail_Activated_Apoptotic_Signaling_Pathway	Human	Bladder	rep_2	2.7e-05
ZDHHC3	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Liver	rep_1	1.0e-70
ZDHHC3	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
ZDHHC3	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Liver	rep_1	1.0e-70
ZDHHC3	GOBP_Regulation_Of_Protein_Localization	Human	Liver	rep_1	2.1e-52
ZDHHC3	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	rep_colon2	1.5e-57
ZDHHC3	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
ZDHHC3	GOBP_Apoptotic_Signaling_Pathway	Human	Intestine	A3	7.0e-12
ZDHHC3	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
ZDHHC3	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
ZDHHC3	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
ZDHHC3	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Intestine	A3	7.6e-11
ZDHHC3	GOBP_Extrinsic_Apoptotic_Signaling_Pathway	Human	Intestine	A3	3.4e-16
ZDHHC3	GOBP_Extrinsic_Apoptotic_Signaling_Pathway_Via_Death_Domain_Receptors	Human	Intestine	A3	5.9e-09
ZDHHC3	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
ZDHHC3	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
ZDHHC3	GOBP_Peptidyl_Amino_Acid_Modification	Human	Intestine	A3	2.7e-09
ZDHHC3	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
ZDHHC3	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
ZDHHC3	GOBP_Protein_Localization_To_Cell_Periphery	Human	Intestine	A3	4.6e-14
ZDHHC3	GOBP_Protein_Localization_To_Cilium	Human	Intestine	A3	1.2e-10
ZDHHC3	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
ZDHHC3	GOBP_Protein_Localization_To_Plasma_Membrane	Human	Intestine	A3	4.0e-10
ZDHHC3	GOBP_Protein_Targeting	Human	Intestine	A3	6.5e-09
ZDHHC3	GOBP_Protein_Targeting_To_Membrane	Human	Intestine	A3	3.5e-07
ZDHHC3	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Intestine	A3	1.1e-07
ZDHHC3	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	A3	7.5e-08
ZDHHC3	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Intestine	A3	4.7e-08
ZDHHC3	GOBP_Synaptic_Signaling	Human	Intestine	A3	5.0e-10
ZDHHC3	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Intestine	A8	1.4e-14
ZDHHC3	GOBP_Lipoprotein_Localization	Human	Intestine	A8	1.2e-11
ZDHHC3	GOBP_Positive_Regulation_Of_Protein_Localization_To_Synapse	Human	Intestine	A8	2.0e-15
ZDHHC3	GOBP_Positive_Regulation_Of_Synaptic_Transmission	Human	Intestine	A8	1.7e-08
ZDHHC3	GOBP_Positive_Regulation_Of_Synaptic_Transmission_Gabaergic	Human	Intestine	A8	2.9e-10
ZDHHC3	GOBP_Protein_Localization_To_Non_Motile_Cilium	Human	Intestine	A8	1.5e-12
ZDHHC3	GOBP_Protein_Localization_To_Photoreceptor_Outer_Segment	Human	Intestine	A8	2.1e-47
ZDHHC3	GOBP_Protein_Palmitoylation	Human	Intestine	A8	9.6e-11
ZDHHC3	GOBP_Receptor_Localization_To_Synapse	Human	Intestine	A8	9.9e-09
ZDHHC3	GOBP_Regulation_Of_Protein_Localization_To_Synapse	Human	Intestine	A8	5.5e-10
ZDHHC3	GOBP_Regulation_Of_Receptor_Localization_To_Synapse	Human	Intestine	A8	1.3e-11
ZDHHC3	GOBP_Regulation_Of_Synaptic_Transmission_Gabaergic	Human	Intestine	A8	2.6e-13
ZDHHC3	GOBP_Synaptic_Transmission_Gabaergic	Human	Intestine	A8	4.3e-14
ZDHHC3	GOBP_Protein_Localization_To_Cilium	Human	Pancreas	PDAC-B-st1	2.6e-05
ZDHHC3	GOBP_Protein_Targeting	Human	Pancreas	PDAC-B-st1	9.4e-05
ZDHHC3	GOBP_Protein_Targeting_To_Membrane	Human	Pancreas	PDAC-B-st1	8.3e-06
ZDHHC3	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Pancreas	PDAC-B-st1	5.9e-05
ZDHHC3	GOBP_Peptidyl_L_Cysteine_S_Palmitoylation	Human	Uterus	rep_1	7.9e-07
ZDHHC3	GOBP_Protein_Localization_To_Cilium	Human	Uterus	rep_25	2.1e-07
ZDHHC3	GOBP_Protein_Localization_To_Non_Motile_Cilium	Human	Uterus	rep_25	7.2e-22
ZDHHC3	GOBP_Protein_Localization_To_Photoreceptor_Outer_Segment	Human	Uterus	rep_25	3.8e-16
ZDHHC3	GOBP_Extrinsic_Apoptotic_Signaling_Pathway	Human	Uterus	rep_26	1.2e-09
ZDHHC3	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Uterus	rep_26	3.5e-06
ZDHHC3	GOBP_Lipoprotein_Localization	Human	Uterus	rep_26	6.7e-08
ZDHHC3	GOBP_Receptor_Localization_To_Synapse	Human	Uterus	rep_26	4.1e-11
ZDHHC3	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Uterus	rep_26	4.8e-06
ZDHHC3	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Uterus	rep_26	1.2e-08
ZDHHC3	GOBP_Synaptic_Signaling	Human	Uterus	rep_26	3.3e-08
ZDHHC3	GOBP_Trail_Activated_Apoptotic_Signaling_Pathway	Human	Uterus	rep_31	1.1e-07
ZDHHC3	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
ZDHHC3	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
ZDHHC3	GOBP_Extrinsic_Apoptotic_Signaling_Pathway_Via_Death_Domain_Receptors	Human	Breast	rep_1	2.6e-08
ZDHHC3	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Breast	rep_1	3.6e-09
ZDHHC3	GOBP_Lipoprotein_Localization	Human	Breast	rep_1	1.8e-07
ZDHHC3	GOBP_Peptidyl_L_Cysteine_S_Palmitoylation	Human	Breast	rep_1	4.1e-13
ZDHHC3	GOBP_Protein_Acylation	Human	Breast	rep_1	1.9e-23
ZDHHC3	GOBP_Protein_Localization_To_Cell_Junction	Human	Breast	rep_1	3.7e-207
ZDHHC3	GOBP_Protein_Localization_To_Cell_Periphery	Human	Breast	rep_1	7.2e-19
ZDHHC3	GOBP_Protein_Localization_To_Plasma_Membrane	Human	Breast	rep_1	1.9e-28
ZDHHC3	GOBP_Protein_Localization_To_Synapse	Human	Breast	rep_1	4.8e-58
ZDHHC3	GOBP_Protein_Palmitoylation	Human	Breast	rep_1	3.3e-12
ZDHHC3	GOBP_Receptor_Localization_To_Synapse	Human	Breast	rep_1	1.4e-27
ZDHHC3	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Breast	rep_1	0.0e+00
ZDHHC3	GOBP_Regulation_Of_Protein_Localization	Human	Breast	rep_1	2.8e-21
ZDHHC3	GOBP_Regulation_Of_Protein_Localization_To_Synapse	Human	Breast	rep_1	3.3e-08
ZDHHC3	GOBP_Regulation_Of_Receptor_Localization_To_Synapse	Human	Breast	rep_1	2.3e-19
ZDHHC3	GOBP_Synaptic_Signaling	Human	Breast	rep_1	3.5e-04
ZDHHC3	GOBP_Trail_Activated_Apoptotic_Signaling_Pathway	Human	Breast	rep_1	3.5e-71
ZDHHC3	GOBP_Extrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_5	7.1e-11
ZDHHC3	GOBP_Positive_Regulation_Of_Protein_Localization_To_Synapse	Human	Breast	rep_5	9.0e-13
ZDHHC3	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
ZDHHC3	GOBP_Positive_Regulation_Of_Synaptic_Transmission	Human	Breast	rep_5	2.7e-12
ZDHHC3	GOBP_Synaptic_Transmission_Gabaergic	Human	Breast	rep_5	1.7e-04
ZDHHC3	GOBP_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	4.8e-09
ZDHHC3	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
ZDHHC3	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Breast	rep_6	3.8e-07
ZDHHC3	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
ZDHHC3	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
ZDHHC3	GOBP_Lipoprotein_Biosynthetic_Process	Human	Breast	rep_6	4.1e-08
ZDHHC3	GOBP_Lipoprotein_Metabolic_Process	Human	Breast	rep_6	1.4e-05
ZDHHC3	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
ZDHHC3	GOBP_Peptidyl_Amino_Acid_Modification	Human	Breast	rep_6	3.8e-05
ZDHHC3	GOBP_Peptidyl_Cysteine_Modification	Human	Breast	rep_6	2.4e-05
ZDHHC3	GOBP_Positive_Regulation_Of_Synaptic_Transmission_Gabaergic	Human	Breast	rep_6	2.0e-09
ZDHHC3	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
ZDHHC3	GOBP_Protein_Localization_To_Cilium	Human	Breast	rep_6	3.4e-15
ZDHHC3	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
ZDHHC3	GOBP_Protein_Targeting	Human	Breast	rep_6	5.5e-10
ZDHHC3	GOBP_Protein_Targeting_To_Membrane	Human	Breast	rep_6	8.6e-10
ZDHHC3	GOBP_Regulation_Of_Synaptic_Transmission_Gabaergic	Human	Breast	rep_6	2.1e-09
ZDHHC3	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Breast	rep_6	1.3e-06
ZDHHC3	GOBP_Protein_Localization_To_Non_Motile_Cilium	Human	Skin	P2_rep2	6.6e-11
ZDHHC3	GOBP_Protein_Localization_To_Photoreceptor_Outer_Segment	Human	Skin	P2_rep2	5.3e-15
ZDHHC3	GOBP_Protein_Localization_To_Cell_Periphery	Human	Skin	P5_rep1	2.4e-09
ZDHHC3	GOBP_Regulation_Of_Receptor_Localization_To_Synapse	Human	Skin	P5_rep1	5.7e-08
ZDHHC3	GOBP_Trail_Activated_Apoptotic_Signaling_Pathway	Human	Skin	P5_rep1	6.2e-09
ZDHHC3	GOBP_Positive_Regulation_Of_Protein_Localization_To_Synapse	Human	Skin	P5_rep3	9.5e-10
ZDHHC3	GOBP_Regulation_Of_Protein_Localization_To_Synapse	Human	Skin	P5_rep3	2.6e-13
ZDHHC3	GOBP_Peptidyl_L_Cysteine_S_Palmitoylation	Human	Skin	P10_rep2	1.7e-09
ZDHHC3	GOBP_Protein_Localization_To_Cilium	Human	Skin	P10_rep2	3.2e-12
ZDHHC3	GOBP_Protein_Palmitoylation	Human	Skin	P10_rep2	3.8e-26
ZDHHC3	GOBP_Lipoprotein_Localization	Human	Skin	P10_rep3	1.3e-17
ZDHHC3	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Lung	rep_2	4.8e-08

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ZDHHC3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ZDHHC3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ZDHHC3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ZDHHC3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ZDHHC3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source