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Spatial pattern gene: TIMMDC1 (spascer ID:51300) |
Gene summary for TIMMDC1 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | TIMMDC1 | Gene ID | 51300 |
| Gene name | translocase of inner mitochondrial membrane domain containing 1 |
| Synonyms | C3orf1|MC1DN31 |
| Cytomap | 3q13.33 |
| Type of gene | protein-coding |
| Description | complex I assembly factor TIMMDC1, mitochondrialM5-14 proteinTIMM domain containing-protein 1translocase of inner mitochondrial membrane domain-containing protein 1transmembrane protein C3orf1 |
| Modification date | 20220513 |
| UniProtAcc | Q9NPL8 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| TIMMDC1 | GO:0005739 | mitochondrion | 21873635 | Component |
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Spatial pattern events for TIMMDC1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| TIMMDC1 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| TIMMDC1 | Human | Liver | rep_liver4 | 34417225 | 2.68e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
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Spatial pattern pathway has TIMMDC1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| TIMMDC1 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Bladder | rep_4 | 1.8e-09 |
| TIMMDC1 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Bladder | rep_4 | 1.1e-14 |
| TIMMDC1 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Intestine | A3 | 1.5e-07 |
| TIMMDC1 | GOBP_Mitochondrion_Organization | Human | Intestine | A3 | 2.3e-19 |
| TIMMDC1 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Intestine | A3 | 3.9e-07 |
| TIMMDC1 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Pancreas | PDAC-B-st1 | 9.9e-05 |
| TIMMDC1 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Pancreas | PDAC-B-st1 | 4.6e-05 |
| TIMMDC1 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Uterus | rep_26 | 2.3e-06 |
| TIMMDC1 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Uterus | rep_26 | 9.9e-07 |
| TIMMDC1 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Breast | rep_6 | 3.3e-04 |
| TIMMDC1 | GOBP_Mitochondrion_Organization | Human | Breast | rep_6 | 2.0e-05 |
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TIMMDC1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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TIMMDC1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for TIMMDC1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for TIMMDC1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for TIMMDC1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| TIMMDC1 | C1838979 | MITOCHONDRIAL COMPLEX I DEFICIENCY | 1 | ORPHANET |
| TIMMDC1 | C4748838 | MITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 31 | 1 | GENOMICS_ENGLAND |
