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Spatial pattern gene: IER5 (spascer ID:51278) |
Gene summary for IER5 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | IER5 | Gene ID | 51278 |
| Gene name | immediate early response 5 |
| Synonyms | SBBI48 |
| Cytomap | 1q25.3 |
| Type of gene | protein-coding |
| Description | immediate early response gene 5 protein |
| Modification date | 20220513 |
| UniProtAcc | Q5VY09 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
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Spatial pattern events for IER5 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| IER5 | Human | Bladder | rep_1 | 34385456 | 8.93e-15 |
| IER5 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| IER5 | Human | Liver | rep_liver1 | 34417225 | 7.15e-09 |
| IER5 | Human | Liver | rep_liver2 | 34417225 | 1.24e-08 |
| IER5 | Human | Liver | rep_liver4 | 34417225 | 2.62e-14 |
| IER5 | Human | Uterus | rep_2 | 34857954 | 1.98e-11 |
| IER5 | Human | Breast | 1160920F | 34493872 | 4.51e-11 |
| IER5 | Human | Breast | CID4290 | 34493872 | 5.87e-10 |
| IER5 | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| IER5 | Human | Skin | P2_rep3 | 32946785 | 6.01e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Bladder_rep_1_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Uterus_rep_2_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4290_H&E  |  |
Breast_CID44971_H&E  |  |
Skin_P2_rep3_H&E  |  |
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Spatial pattern pathway has IER5 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| IER5 | GOBP_Regulation_Of_Response_To_Stress | Human | Brain | rep_1 | 4.6e-05 |
| IER5 | GOBP_Regulation_Of_Response_To_Stress | Human | Liver | rep_1 | 5.3e-67 |
| IER5 | GOBP_Regulation_Of_Response_To_Stress | Human | Intestine | rep_colon4 | 2.2e-52 |
| IER5 | GOBP_Cellular_Response_To_Heat | Human | Intestine | A3 | 2.1e-21 |
| IER5 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Intestine | A3 | 5.1e-13 |
| IER5 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Intestine | A3 | 9.4e-13 |
| IER5 | GOBP_Regulation_Of_Cellular_Response_To_Stress | Human | Intestine | A3 | 7.7e-17 |
| IER5 | GOBP_Regulation_Of_Response_To_Stress | Human | Intestine | A3 | 1.1e-10 |
| IER5 | GOBP_Response_To_Abiotic_Stimulus | Human | Intestine | A3 | 5.3e-18 |
| IER5 | GOBP_Response_To_Heat | Human | Intestine | A3 | 7.0e-22 |
| IER5 | GOBP_Response_To_Temperature_Stimulus | Human | Intestine | A3 | 4.2e-20 |
| IER5 | GOBP_Regulation_Of_Cellular_Response_To_Heat | Human | Intestine | A8 | 3.0e-08 |
| IER5 | GOBP_Cellular_Response_To_Heat | Human | Uterus | rep_25 | 6.3e-09 |
| IER5 | GOBP_Regulation_Of_Cellular_Response_To_Heat | Human | Uterus | rep_25 | 1.4e-10 |
| IER5 | GOBP_Response_To_Temperature_Stimulus | Human | Uterus | rep_25 | 8.0e-06 |
| IER5 | GOBP_Response_To_Heat | Human | Uterus | rep_26 | 3.4e-07 |
| IER5 | GOBP_Regulation_Of_Cellular_Response_To_Heat | Human | Breast | rep_1 | 1.9e-16 |
| IER5 | GOBP_Regulation_Of_Response_To_Stress | Human | Breast | rep_1 | 3.4e-19 |
| IER5 | GOBP_Response_To_Abiotic_Stimulus | Human | Breast | rep_1 | 2.6e-19 |
| IER5 | GOBP_Response_To_Temperature_Stimulus | Human | Breast | rep_1 | 1.2e-34 |
| IER5 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Human | Breast | rep_5 | 8.0e-09 |
| IER5 | GOBP_Regulation_Of_Cellular_Response_To_Stress | Human | Breast | rep_5 | 8.1e-10 |
| IER5 | GOBP_Cellular_Response_To_Heat | Human | Breast | rep_6 | 1.3e-04 |
| IER5 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Human | Breast | rep_6 | 4.2e-06 |
| IER5 | GOBP_Regulation_Of_Cellular_Response_To_Heat | Human | Skin | P10_rep2 | 7.2e-13 |
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IER5 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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IER5 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for IER5 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for IER5 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for IER5 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
