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Spatial pattern gene: MRPL27 (spascer ID:51264) |
Gene summary for MRPL27 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | MRPL27 | Gene ID | 51264 |
| Gene name | mitochondrial ribosomal protein L27 |
| Synonyms | L27mt |
| Cytomap | 17q21.33 |
| Type of gene | protein-coding |
| Description | 39S ribosomal protein L27, mitochondrialMRP-L27mitochondrial large ribosomal subunit protein bL27m |
| Modification date | 20220513 |
| UniProtAcc | Q9P0M9 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| MRPL27 | GO:0003735 | structural constituent of ribosome | 21873635 | Function |
| MRPL27 | GO:0005762 | mitochondrial large ribosomal subunit | 21873635 | Component |
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Spatial pattern events for MRPL27 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| MRPL27 | Human | Intestine | rep_colon1 | 34417225 | 3.91e-12 |
| MRPL27 | Human | Intestine | rep_colon2 | 34417225 | 2.85e-15 |
| MRPL27 | Human | Intestine | rep_colon3 | 34417225 | 7.35e-08 |
| MRPL27 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| MRPL27 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| MRPL27 | Human | Liver | rep_liver4 | 34417225 | 1.24e-09 |
| MRPL27 | Human | Intestine | A2 | 33406409 | 3.85e-15 |
| MRPL27 | Human | Breast | F2 | 34650042 | 7.64e-14 |
| MRPL27 | Human | Breast | 1142243F | 34493872 | 2.30e-15 |
| MRPL27 | Human | Breast | 1160920F | 34493872 | 2.68e-15 |
| MRPL27 | Human | Lung | rep_1 | 35355018 | 5.63e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon3_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Intestine_A2_H&E  |  |
Breast_F2_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_1160920F_H&E  |  |
Lung_rep_1_H&E  |  |
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Spatial pattern pathway has MRPL27 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| MRPL27 | GOBP_Amide_Biosynthetic_Process | Human | Intestine | A1 | 6.4e-07 |
| MRPL27 | GOBP_Peptide_Biosynthetic_Process | Human | Intestine | A1 | 4.6e-10 |
| MRPL27 | GOBP_Translational_Elongation | Human | Intestine | A1 | 6.7e-08 |
| MRPL27 | GOBP_Translational_Termination | Human | Intestine | A1 | 3.9e-07 |
| MRPL27 | GOBP_Cellular_Component_Disassembly | Human | Intestine | A3 | 1.0e-14 |
| MRPL27 | GOBP_Mitochondrial_Gene_Expression | Human | Intestine | A8 | 1.4e-08 |
| MRPL27 | GOBP_Mitochondrial_Translation | Human | Intestine | A8 | 1.7e-08 |
| MRPL27 | GOBP_Mitochondrial_Translation | Human | Pancreas | PDAC-B-st1 | 5.1e-05 |
| MRPL27 | GOBP_Translational_Termination | Human | Uterus | rep_1 | 5.2e-09 |
| MRPL27 | GOBP_Mitochondrial_Translation | Human | Uterus | rep_25 | 3.6e-06 |
| MRPL27 | GOBP_Translational_Elongation | Human | Uterus | rep_25 | 9.9e-08 |
| MRPL27 | GOBP_Cellular_Component_Disassembly | Human | Uterus | rep_26 | 2.7e-06 |
| MRPL27 | GOBP_Mitochondrial_Gene_Expression | Human | Uterus | rep_26 | 1.3e-15 |
| MRPL27 | GOBP_Translational_Termination | Human | Breast | rep_1 | 7.0e-06 |
| MRPL27 | GOBP_Cellular_Component_Disassembly | Human | Breast | rep_5 | 2.0e-06 |
| MRPL27 | GOBP_Amide_Biosynthetic_Process | Human | Breast | rep_6 | 8.7e-05 |
| MRPL27 | GOBP_Cellular_Amide_Metabolic_Process | Human | Breast | rep_6 | 5.6e-05 |
| MRPL27 | GOBP_Mitochondrial_Gene_Expression | Human | Breast | rep_6 | 9.9e-07 |
| MRPL27 | GOBP_Mitochondrial_Translation | Human | Breast | rep_6 | 1.3e-06 |
| MRPL27 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Human | Breast | rep_6 | 1.2e-09 |
| MRPL27 | GOBP_Peptide_Biosynthetic_Process | Human | Breast | rep_6 | 1.6e-05 |
| MRPL27 | GOBP_Peptide_Metabolic_Process | Human | Breast | rep_6 | 8.7e-05 |
| MRPL27 | GOBP_Protein_Containing_Complex_Disassembly | Human | Breast | rep_6 | 1.0e-13 |
| MRPL27 | GOBP_Translational_Termination | Human | Skin | P10_rep1 | 6.7e-10 |
| MRPL27 | GOBP_Cellular_Component_Disassembly | Human | Lung | rep_2 | 5.6e-07 |
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MRPL27 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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MRPL27 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for MRPL27 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for MRPL27 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MRPL27 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
