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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: NT5C3A (spascer ID:51251)

Gene summary for NT5C3A

Gene summary

Gene information
	Species	Human
	Gene symbol	NT5C3A
	Gene ID	51251
	Gene name	5'-nucleotidase, cytosolic IIIA
	Synonyms	NT5C3\|P5'N-1\|P5N-1\|PN-I\|POMP\|PSN1\|UMPH\|UMPH1\|cN-III\|hUMP1\|p36
	Cytomap	7p14.3
	Type of gene	protein-coding
	Description	cytosolic 5'-nucleotidase 3A5'-nucleotidase, cytosolic III7-methylguanosine phosphate-specific 5'-nucleotidasecytosolic 5'-nucleotidase 3lupinpyrimidine 5'-nucleotidase 1uridine 5'-monophosphate hydrolase 1
	Modification date	20220513
	UniProtAcc	Q9H0P0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
NT5C3A	GO:0005737	cytoplasm	21873635	Component
NT5C3A	GO:0008253	5'-nucleotidase activity	21873635	Function

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Spatial pattern events for NT5C3A

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
NT5C3A	Human	Intestine	rep_colon1	34417225	4.27e-10
NT5C3A	Human	Liver	rep_liver1	34417225	1.08e-15
NT5C3A	Human	Liver	rep_liver2	34417225	6.98e-16
NT5C3A	Human	Intestine	A1	33406409	2.09e-15
NT5C3A	Human	Intestine	A2	33406409	3.32e-11
NT5C3A	Human	Breast	1160920F	34493872	3.47e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Breast_1160920F_H&E

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Spatial pattern pathway has NT5C3A envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
NT5C3A	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
NT5C3A	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
NT5C3A	GOBP_Defense_Response_To_Other_Organism	Human	Brain	rep_4	1.2e-64
NT5C3A	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
NT5C3A	GOBP_Defense_Response_To_Other_Organism	Human	Liver	rep_1	4.3e-69
NT5C3A	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
NT5C3A	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
NT5C3A	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	rep_colon4	1.2e-82
NT5C3A	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
NT5C3A	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
NT5C3A	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
NT5C3A	GOBP_Dephosphorylation	Human	Intestine	A3	3.1e-14
NT5C3A	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
NT5C3A	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Intestine	A3	9.9e-10
NT5C3A	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Intestine	A3	5.9e-24
NT5C3A	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
NT5C3A	GOBP_Organophosphate_Metabolic_Process	Human	Intestine	A3	4.4e-13
NT5C3A	GOBP_Pyrimidine_Containing_Compound_Metabolic_Process	Human	Intestine	A3	9.4e-08
NT5C3A	GOBP_Response_To_Virus	Human	Intestine	A3	2.4e-11
NT5C3A	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Intestine	A8	3.2e-10
NT5C3A	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	A8	5.3e-08
NT5C3A	GOBP_Glycosyl_Compound_Catabolic_Process	Human	Intestine	A8	3.3e-07
NT5C3A	GOBP_Glycosyl_Compound_Metabolic_Process	Human	Intestine	A8	2.8e-08
NT5C3A	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Human	Intestine	A8	1.9e-11
NT5C3A	GOBP_Nucleoside_Catabolic_Process	Human	Intestine	A8	1.3e-18
NT5C3A	GOBP_Nucleoside_Metabolic_Process	Human	Intestine	A8	4.8e-09
NT5C3A	GOBP_Pyrimidine_Nucleoside_Catabolic_Process	Human	Intestine	A8	2.3e-13
NT5C3A	GOBP_Pyrimidine_Nucleoside_Metabolic_Process	Human	Intestine	A8	1.1e-11
NT5C3A	GOBP_Small_Molecule_Catabolic_Process	Human	Intestine	A8	2.2e-13
NT5C3A	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
NT5C3A	GOBP_Defense_Response_To_Other_Organism	Human	Uterus	rep_4	2.0e-31
NT5C3A	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
NT5C3A	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
NT5C3A	GOBP_Glycosyl_Compound_Catabolic_Process	Human	Uterus	rep_25	4.5e-07
NT5C3A	GOBP_Nucleoside_Catabolic_Process	Human	Uterus	rep_25	2.2e-08
NT5C3A	GOBP_Pyrimidine_Nucleoside_Catabolic_Process	Human	Uterus	rep_25	1.7e-12
NT5C3A	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Uterus	rep_26	5.1e-11
NT5C3A	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	2.9e-07
NT5C3A	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	2.4e-06
NT5C3A	GOBP_Nucleoside_Metabolic_Process	Human	Uterus	rep_26	7.6e-12
NT5C3A	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Uterus	rep_26	2.6e-06
NT5C3A	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
NT5C3A	GOBP_Pyrimidine_Containing_Compound_Catabolic_Process	Human	Uterus	rep_26	5.8e-09
NT5C3A	GOBP_Pyrimidine_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.8e-08
NT5C3A	GOBP_Response_To_Virus	Human	Uterus	rep_26	1.3e-09
NT5C3A	GOBP_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	9.1e-13
NT5C3A	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
NT5C3A	GOBP_Nucleoside_Catabolic_Process	Human	Breast	rep_1	8.0e-06
NT5C3A	GOBP_Pyrimidine_Containing_Compound_Catabolic_Process	Human	Breast	rep_1	2.8e-19
NT5C3A	GOBP_Pyrimidine_Nucleoside_Catabolic_Process	Human	Breast	rep_1	1.1e-80
NT5C3A	GOBP_Pyrimidine_Nucleoside_Metabolic_Process	Human	Breast	rep_1	8.4e-07
NT5C3A	GOBP_Response_To_Virus	Human	Breast	rep_1	7.9e-19
NT5C3A	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Breast	rep_5	1.1e-09
NT5C3A	GOBP_Glycosyl_Compound_Catabolic_Process	Human	Breast	rep_5	5.9e-10
NT5C3A	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Human	Breast	rep_5	2.3e-06
NT5C3A	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
NT5C3A	GOBP_Dephosphorylation	Human	Breast	rep_6	2.8e-05
NT5C3A	GOBP_Glycosyl_Compound_Metabolic_Process	Human	Breast	rep_6	1.2e-07
NT5C3A	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	1.7e-10
NT5C3A	GOBP_Nucleoside_Metabolic_Process	Human	Breast	rep_6	8.1e-07
NT5C3A	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Breast	rep_6	7.7e-08
NT5C3A	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
NT5C3A	GOBP_Organophosphate_Metabolic_Process	Human	Breast	rep_6	1.0e-12
NT5C3A	GOBP_Pyrimidine_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	6.5e-06
NT5C3A	GOBP_Small_Molecule_Catabolic_Process	Human	Breast	rep_6	4.7e-07
NT5C3A	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
NT5C3A	GOBP_Glycosyl_Compound_Catabolic_Process	Human	Skin	P2_rep2	9.2e-12
NT5C3A	GOBP_Pyrimidine_Nucleoside_Metabolic_Process	Human	Skin	P9_rep2	1.0e-10
NT5C3A	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
NT5C3A	GOBP_Defense_Response_To_Other_Organism	Human	Lung	rep_1	1.5e-09

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NT5C3A function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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NT5C3A function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for NT5C3A envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for NT5C3A

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for NT5C3A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
NT5C3A	C1849507	Uridine 5-Prime Monophosphate Hydrolase Deficiency, Hemolytic Anemia due to	10	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
NT5C3A	C0002882	Anemia, Hemolytic, Congenital Nonspherocytic	1	CTD_human
NT5C3A	C0263454	Chloracne	1	CTD_human