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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: PDZD11 (spascer ID:51248)

Gene summary for PDZD11

Gene summary

Gene information
	Species	Human
	Gene symbol	PDZD11
	Gene ID	51248
	Gene name	PDZ domain containing 11
	Synonyms	AIPP1\|PDZK11\|PISP
	Cytomap	Xq13.1
	Type of gene	protein-coding
	Description	PDZ domain-containing protein 11ATPase-interacting PDZ proteinPMCA-interacting single-PDZ proteinplasma membrane calcium ATPase-interacting single-PDZ protein
	Modification date	20220513
	UniProtAcc	Q5EBL8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
PDZD11	GO:0005911	cell-cell junction	21873635	Component
PDZD11	GO:0007269	neurotransmitter secretion	21873635	Process
PDZD11	GO:0016323	basolateral plasma membrane	21873635	Component
PDZD11	GO:0045199	maintenance of epithelial cell apical/basal polarity	21873635	Process
PDZD11	GO:0045202	synapse	21873635	Component
PDZD11	GO:1903361	protein localization to basolateral plasma membrane	21873635	Process

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Spatial pattern events for PDZD11

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
PDZD11	Human	Liver	rep_liver1	34417225	1.08e-15
PDZD11	Human	Liver	rep_liver2	34417225	6.98e-16
PDZD11	Human	Uterus	rep_3	34857954	1.66e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_3_H&E

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Spatial pattern pathway has PDZD11 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
PDZD11	GOBP_Humoral_Immune_Response	Human	Brain	rep_1	8.1e-16
PDZD11	GOBP_Transmembrane_Transport	Human	Brain	rep_1	2.8e-23
PDZD11	GOBP_Humoral_Immune_Response	Human	Liver	rep_1	9.0e-62
PDZD11	GOBP_Transmembrane_Transport	Human	Liver	rep_1	1.0e-70
PDZD11	GOBP_Humoral_Immune_Response	Human	Intestine	rep_colon4	1.3e-27
PDZD11	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
PDZD11	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
PDZD11	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Human	Intestine	A3	8.2e-09
PDZD11	GOBP_Humoral_Immune_Response	Human	Intestine	A3	1.4e-08
PDZD11	GOBP_Protein_Localization_To_Cell_Periphery	Human	Intestine	A3	4.6e-14
PDZD11	GOBP_Secretion	Human	Intestine	A3	1.8e-13
PDZD11	GOBP_Synaptic_Signaling	Human	Intestine	A3	5.0e-10
PDZD11	GOBP_Transmembrane_Transport	Human	Intestine	A3	1.4e-10
PDZD11	GOBP_Antimicrobial_Humoral_Response	Human	Intestine	A8	4.6e-10
PDZD11	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Human	Intestine	A8	5.4e-11
PDZD11	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Human	Intestine	A8	8.2e-16
PDZD11	GOBP_Maintenance_Of_Apical_Basal_Cell_Polarity	Human	Intestine	A8	2.1e-15
PDZD11	GOBP_Maintenance_Of_Cell_Polarity	Human	Intestine	A8	3.2e-16
PDZD11	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
PDZD11	GOBP_Neurotransmitter_Secretion	Human	Intestine	A8	3.4e-11
PDZD11	GOBP_Neurotransmitter_Transport	Human	Intestine	A8	7.1e-13
PDZD11	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
PDZD11	GOBP_Pore_Complex_Assembly	Human	Intestine	A8	2.3e-11
PDZD11	GOBP_Regulation_Of_Neurotransmitter_Levels	Human	Intestine	A8	1.4e-10
PDZD11	GOBP_Signal_Release	Human	Intestine	A8	6.9e-14
PDZD11	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
PDZD11	GOBP_Sulfur_Compound_Metabolic_Process	Human	Intestine	A8	2.5e-14
PDZD11	GOBP_Vitamin_Metabolic_Process	Human	Intestine	A8	1.8e-09
PDZD11	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Human	Intestine	A8	5.2e-09
PDZD11	GOBP_Neurotransmitter_Transport	Human	Pancreas	PDAC-B-st1	5.7e-05
PDZD11	GOBP_Pantothenate_Metabolic_Process	Human	Pancreas	PDAC-B-st1	3.2e-05
PDZD11	GOBP_Regulation_Of_Neurotransmitter_Levels	Human	Pancreas	PDAC-B-st1	8.5e-06
PDZD11	GOBP_Vitamin_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.8e-07
PDZD11	GOBP_Humoral_Immune_Response	Human	Uterus	rep_4	2.0e-31
PDZD11	GOBP_Antimicrobial_Humoral_Response	Human	Uterus	rep_1	5.2e-06
PDZD11	GOBP_Neurotransmitter_Transport	Human	Uterus	rep_1	4.8e-08
PDZD11	GOBP_Pore_Complex_Assembly	Human	Uterus	rep_25	2.3e-06
PDZD11	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	8.7e-10
PDZD11	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Human	Uterus	rep_26	3.5e-06
PDZD11	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
PDZD11	GOBP_Pantothenate_Metabolic_Process	Human	Uterus	rep_26	9.0e-07
PDZD11	GOBP_Sulfur_Compound_Metabolic_Process	Human	Uterus	rep_26	8.8e-08
PDZD11	GOBP_Synaptic_Signaling	Human	Uterus	rep_26	3.3e-08
PDZD11	GOBP_Vitamin_Metabolic_Process	Human	Uterus	rep_26	3.9e-06
PDZD11	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
PDZD11	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Human	Breast	rep_1	2.3e-10
PDZD11	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Human	Breast	rep_1	7.5e-74
PDZD11	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Human	Breast	rep_1	1.1e-43
PDZD11	GOBP_Maintenance_Of_Apical_Basal_Cell_Polarity	Human	Breast	rep_1	6.4e-16
PDZD11	GOBP_Maintenance_Of_Cell_Polarity	Human	Breast	rep_1	2.4e-46
PDZD11	GOBP_Pore_Complex_Assembly	Human	Breast	rep_1	4.0e-05
PDZD11	GOBP_Protein_Localization_To_Basolateral_Plasma_Membrane	Human	Breast	rep_1	2.8e-19
PDZD11	GOBP_Protein_Localization_To_Cell_Periphery	Human	Breast	rep_1	7.2e-19
PDZD11	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
PDZD11	GOBP_Synaptic_Signaling	Human	Breast	rep_1	3.5e-04
PDZD11	GOBP_Transmembrane_Transport	Human	Breast	rep_1	3.2e-56
PDZD11	GOBP_Vitamin_Metabolic_Process	Human	Breast	rep_1	3.1e-13
PDZD11	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Human	Breast	rep_1	2.6e-13
PDZD11	GOBP_Antimicrobial_Humoral_Response	Human	Breast	rep_4	8.7e-07
PDZD11	GOBP_Neurotransmitter_Secretion	Human	Breast	rep_5	1.5e-04
PDZD11	GOBP_Regulation_Of_Neurotransmitter_Levels	Human	Breast	rep_5	2.2e-04
PDZD11	GOBP_Signal_Release	Human	Breast	rep_5	1.1e-10
PDZD11	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
PDZD11	GOBP_Cellular_Amide_Metabolic_Process	Human	Breast	rep_6	5.6e-05
PDZD11	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
PDZD11	GOBP_Neurotransmitter_Transport	Human	Breast	rep_6	9.5e-06
PDZD11	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
PDZD11	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
PDZD11	GOBP_Sulfur_Compound_Metabolic_Process	Human	Breast	rep_6	3.0e-10
PDZD11	GOBP_Maintenance_Of_Cell_Polarity	Human	Skin	P5_rep1	5.2e-14
PDZD11	GOBP_Protein_Localization_To_Cell_Periphery	Human	Skin	P5_rep1	2.4e-09
PDZD11	GOBP_Maintenance_Of_Apical_Basal_Cell_Polarity	Human	Skin	P5_rep3	9.6e-16
PDZD11	GOBP_Antimicrobial_Humoral_Response	Human	Lung	rep_1	1.3e-10
PDZD11	GOBP_Humoral_Immune_Response	Human	Lung	rep_1	1.7e-10

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PDZD11 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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PDZD11 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for PDZD11 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for PDZD11

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for PDZD11

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source