|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: EMC4 (spascer ID:51234) |
Gene summary for EMC4 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | EMC4 | Gene ID | 51234 |
| Gene name | ER membrane protein complex subunit 4 |
| Synonyms | PIG17|TMEM85 |
| Cytomap | 15q14 |
| Type of gene | protein-coding |
| Description | ER membrane protein complex subunit 4cell proliferation-inducing gene 17 proteintransmembrane protein 85 |
| Modification date | 20220513 |
| UniProtAcc | Q5J8M3 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| EMC4 | GO:0072546 | EMC complex | 21873635 | Component |
Top |
Spatial pattern events for EMC4 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| EMC4 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| EMC4 | Human | Intestine | rep_colon2 | 34417225 | 4.72e-06 |
| EMC4 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| EMC4 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| EMC4 | Human | Liver | rep_liver4 | 34417225 | 1.39e-15 |
| EMC4 | Human | Uterus | rep_2 | 34857954 | 8.94e-10 |
| EMC4 | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| EMC4 | Human | Uterus | rep_4 | 34857954 | 5.00e-14 |
| EMC4 | Human | Breast | 1160920F | 34493872 | 6.42e-09 |
| EMC4 | Human | Lung | rep_1 | 35355018 | 4.78e-06 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
Uterus_rep_4_H&E  |  |
Breast_1160920F_H&E  |  |
Lung_rep_1_H&E  |  |
Top |
Spatial pattern pathway has EMC4 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| EMC4 | GOBP_Cellular_Macromolecule_Localization | Human | Intestine | A3 | 1.7e-09 |
| EMC4 | GOBP_Endomembrane_System_Organization | Human | Intestine | A3 | 1.6e-16 |
| EMC4 | GOBP_Establishment_Of_Protein_Localization | Human | Intestine | A3 | 5.0e-10 |
| EMC4 | GOBP_Establishment_Of_Protein_Localization_To_Membrane | Human | Intestine | A3 | 7.6e-11 |
| EMC4 | GOBP_Membrane_Organization | Human | Intestine | A3 | 2.7e-18 |
| EMC4 | GOBP_Protein_Insertion_Into_Membrane | Human | Intestine | A3 | 2.2e-07 |
| EMC4 | GOBP_Protein_Localization_To_Organelle | Human | Intestine | A3 | 1.5e-12 |
| EMC4 | GOBP_Endoplasmic_Reticulum_Organization | Human | Intestine | A8 | 3.1e-12 |
| EMC4 | GOBP_Protein_Insertion_Into_Er_Membrane | Human | Intestine | A8 | 2.8e-16 |
| EMC4 | GOBP_Protein_Insertion_Into_Er_Membrane_By_Stop_Transfer_Membrane_Anchor_Sequence | Human | Intestine | A8 | 7.4e-11 |
| EMC4 | GOBP_Tail_Anchored_Membrane_Protein_Insertion_Into_Er_Membrane | Human | Intestine | A8 | 2.7e-20 |
| EMC4 | GOBP_Endoplasmic_Reticulum_Organization | Human | Pancreas | PDAC-B-st1 | 4.9e-05 |
| EMC4 | GOBP_Protein_Insertion_Into_Er_Membrane | Human | Uterus | rep_1 | 7.6e-08 |
| EMC4 | GOBP_Protein_Insertion_Into_Membrane | Human | Uterus | rep_1 | 7.9e-06 |
| EMC4 | GOBP_Protein_Insertion_Into_Er_Membrane_By_Stop_Transfer_Membrane_Anchor_Sequence | Human | Uterus | rep_25 | 2.9e-19 |
| EMC4 | GOBP_Endoplasmic_Reticulum_Organization | Human | Uterus | rep_26 | 2.8e-06 |
| EMC4 | GOBP_Tail_Anchored_Membrane_Protein_Insertion_Into_Er_Membrane | Human | Uterus | rep_26 | 1.5e-07 |
| EMC4 | GOBP_Cellular_Macromolecule_Localization | Human | Breast | rep_1 | 3.7e-09 |
| EMC4 | GOBP_Endomembrane_System_Organization | Human | Breast | rep_1 | 2.2e-04 |
| EMC4 | GOBP_Establishment_Of_Protein_Localization | Human | Breast | rep_1 | 7.2e-05 |
| EMC4 | GOBP_Protein_Insertion_Into_Er_Membrane_By_Stop_Transfer_Membrane_Anchor_Sequence | Human | Breast | rep_5 | 3.6e-05 |
| EMC4 | GOBP_Tail_Anchored_Membrane_Protein_Insertion_Into_Er_Membrane | Human | Breast | rep_5 | 2.8e-04 |
| EMC4 | GOBP_Endoplasmic_Reticulum_Organization | Human | Breast | rep_6 | 5.1e-06 |
| EMC4 | GOBP_Establishment_Of_Protein_Localization_To_Membrane | Human | Breast | rep_6 | 3.8e-07 |
| EMC4 | GOBP_Protein_Insertion_Into_Membrane | Human | Breast | rep_6 | 7.3e-08 |
| EMC4 | GOBP_Protein_Localization_To_Organelle | Human | Breast | rep_6 | 1.1e-07 |
| EMC4 | GOBP_Protein_Insertion_Into_Er_Membrane_By_Stop_Transfer_Membrane_Anchor_Sequence | Human | Skin | P10_rep2 | 5.3e-10 |
Top |
EMC4 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
EMC4 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for EMC4 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for EMC4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for EMC4 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
