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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: PCNA (spascer ID:5111)

Gene summary for PCNA

Gene summary

Gene information
	Species	Human
	Gene symbol	PCNA
	Gene ID	5111
	Gene name	proliferating cell nuclear antigen
	Synonyms	ATLD2
	Cytomap	20p12.3
	Type of gene	protein-coding
	Description	proliferating cell nuclear antigenDNA polymerase delta auxiliary proteincyclin
	Modification date	20220513
	UniProtAcc	P12004

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
PCNA	GO:0006272	leading strand elongation	21873635	Process
PCNA	GO:0006298	mismatch repair	21873635	Process
PCNA	GO:0019985	translesion synthesis	21873635	Process
PCNA	GO:0030337	DNA polymerase processivity factor activity	21873635	Function
PCNA	GO:0043626	PCNA complex	21873635	Component

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Spatial pattern events for PCNA

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
PCNA	Human	Brain	rep_9	33558695	5.72e-11
PCNA	Human	Brain	rep_10	33558695	8.07e-07
PCNA	Human	Bladder	rep_2	34385456	6.29e-15
PCNA	Human	Intestine	rep_colon1	34417225	1.95e-15
PCNA	Human	Intestine	rep_colon2	34417225	8.12e-16
PCNA	Human	Intestine	rep_colon4	34417225	2.06e-15
PCNA	Human	Liver	rep_liver1	34417225	1.08e-15
PCNA	Human	Liver	rep_liver2	34417225	6.98e-16
PCNA	Human	Liver	rep_liver4	34417225	7.71e-16
PCNA	Human	Intestine	A1	33406409	6.31e-15
PCNA	Human	Intestine	A2	33406409	3.85e-15
PCNA	Human	Uterus	rep_1	34857954	5.13e-15
PCNA	Human	Uterus	rep_3	34857954	1.66e-15
PCNA	Human	Breast	A5	34650042	5.60e-10
PCNA	Human	Breast	B5	34650042	1.73e-06
PCNA	Human	Breast	B6	34650042	2.87e-06
PCNA	Human	Breast	1142243F	34493872	4.15e-15
PCNA	Human	Breast	1160920F	34493872	1.48e-15
PCNA	Human	Breast	CID4465	34493872	5.00e-09
PCNA	Human	Breast	CID44971	34493872	1.76e-15
PCNA	Human	Breast	CID4535	34493872	8.50e-07
PCNA	Human	Skin	P2_rep2	32946785	6.52e-07
PCNA	Human	Skin	P2_rep3	32946785	3.96e-08
PCNA	Human	Skin	mel1_rep2	30154148	1.39e-11
PCNA	Human	Lung	rep_1	35355018	4.99e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_9_H&E
Brain_rep_10_H&E
Bladder_rep_2_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_1_H&E
Uterus_rep_3_H&E
Breast_A5_H&E
Breast_B5_H&E
Breast_B6_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Skin_P2_rep3_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has PCNA envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
PCNA	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
PCNA	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
PCNA	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
PCNA	GOBP_Regulation_Of_Response_To_Stress	Human	Brain	rep_1	4.6e-05
PCNA	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
PCNA	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
PCNA	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
PCNA	GOBP_Response_To_Hormone	Human	Brain	rep_10	2.8e-23
PCNA	GOBP_Response_To_Lipid	Human	Brain	rep_10	2.8e-23
PCNA	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
PCNA	GOBP_Response_To_Ketone	Human	Brain	rep_11	2.5e-12
PCNA	GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Brain	st	1.5e-45
PCNA	GOBP_Cellular_Response_To_Abiotic_Stimulus	Human	Bladder	rep_2	7.0e-07
PCNA	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
PCNA	GOBP_Response_To_Corticosteroid	Human	Bladder	rep_2	3.3e-18
PCNA	GOBP_Response_To_Estradiol	Human	Bladder	rep_2	1.6e-18
PCNA	GOBP_Dna_Dependent_Dna_Replication	Human	Bladder	rep_4	5.7e-05
PCNA	GOBP_Regulation_Of_Dna_Directed_Dna_Polymerase_Activity	Human	Bladder	rep_4	3.3e-05
PCNA	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
PCNA	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
PCNA	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
PCNA	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
PCNA	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
PCNA	GOBP_Regulation_Of_Response_To_Stress	Human	Liver	rep_1	5.3e-67
PCNA	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
PCNA	GOBP_Response_To_Hormone	Human	Liver	rep_1	3.0e-55
PCNA	GOBP_Response_To_Ketone	Human	Liver	rep_1	1.7e-73
PCNA	GOBP_Response_To_Lipid	Human	Liver	rep_1	3.0e-55
PCNA	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
PCNA	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
PCNA	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
PCNA	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
PCNA	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
PCNA	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
PCNA	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	rep_colon4	2.2e-52
PCNA	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
PCNA	GOBP_Response_To_Hormone	Human	Intestine	rep_liver2	3.7e-39
PCNA	GOBP_Response_To_Ketone	Human	Intestine	rep_liver2	8.9e-16
PCNA	GOBP_Response_To_Lipid	Human	Intestine	rep_liver2	3.7e-39
PCNA	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
PCNA	GOBP_Positive_Regulation_Of_Deoxyribonuclease_Activity	Human	Intestine	A1	1.0e-07
PCNA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
PCNA	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
PCNA	GOBP_Cell_Cycle_Phase_Transition	Human	Intestine	A3	3.5e-07
PCNA	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
PCNA	GOBP_Cellular_Response_To_Chemical_Stress	Human	Intestine	A3	1.1e-11
PCNA	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	6.6e-16
PCNA	GOBP_Cellular_Response_To_Radiation	Human	Intestine	A3	6.7e-10
PCNA	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
PCNA	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
PCNA	GOBP_Dna_Biosynthetic_Process	Human	Intestine	A3	9.4e-13
PCNA	GOBP_Dna_Dependent_Dna_Replication	Human	Intestine	A3	2.2e-07
PCNA	GOBP_Dna_Metabolic_Process	Human	Intestine	A3	1.2e-09
PCNA	GOBP_Dna_Repair	Human	Intestine	A3	4.4e-09
PCNA	GOBP_Dna_Replication	Human	Intestine	A3	2.5e-08
PCNA	GOBP_Gland_Development	Human	Intestine	A3	2.3e-14
PCNA	GOBP_Heart_Development	Human	Intestine	A3	3.2e-07
PCNA	GOBP_Hepaticobiliary_System_Development	Human	Intestine	A3	1.6e-07
PCNA	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
PCNA	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
PCNA	GOBP_Multicellular_Organism_Reproduction	Human	Intestine	A3	4.1e-15
PCNA	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Intestine	A3	5.9e-17
PCNA	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
PCNA	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	1.9e-15
PCNA	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Human	Intestine	A3	1.9e-08
PCNA	GOBP_Nucleotide_Excision_Repair	Human	Intestine	A3	8.1e-09
PCNA	GOBP_Ovulation_Cycle	Human	Intestine	A3	2.4e-10
PCNA	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Intestine	A3	3.2e-16
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	2.3e-19
PCNA	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Intestine	A3	3.1e-07
PCNA	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
PCNA	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
PCNA	GOBP_Positive_Regulation_Of_Nuclease_Activity	Human	Intestine	A3	8.5e-18
PCNA	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
PCNA	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Intestine	A3	2.1e-11
PCNA	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Intestine	A3	1.2e-13
PCNA	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	1.8e-12
PCNA	GOBP_Regeneration	Human	Intestine	A3	5.3e-11
PCNA	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
PCNA	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	2.6e-08
PCNA	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
PCNA	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Intestine	A3	7.7e-17
PCNA	GOBP_Regulation_Of_Dna_Dependent_Dna_Replication	Human	Intestine	A3	3.7e-07
PCNA	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Intestine	A3	2.8e-10
PCNA	GOBP_Regulation_Of_Dna_Replication	Human	Intestine	A3	2.9e-12
PCNA	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
PCNA	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
PCNA	GOBP_Regulation_Of_Nuclease_Activity	Human	Intestine	A3	1.9e-17
PCNA	GOBP_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	1.1e-13
PCNA	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	A3	1.1e-10
PCNA	GOBP_Regulation_Of_Transferase_Activity	Human	Intestine	A3	3.9e-10
PCNA	GOBP_Reproduction	Human	Intestine	A3	4.6e-19
PCNA	GOBP_Response_To_Abiotic_Stimulus	Human	Intestine	A3	5.3e-18
PCNA	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
PCNA	GOBP_Response_To_Inorganic_Substance	Human	Intestine	A3	6.8e-07
PCNA	GOBP_Response_To_Light_Stimulus	Human	Intestine	A3	9.1e-14
PCNA	GOBP_Response_To_Lipid	Human	Intestine	A3	1.7e-09
PCNA	GOBP_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	3.2e-15
PCNA	GOBP_Response_To_Oxidative_Stress	Human	Intestine	A3	5.4e-18
PCNA	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
PCNA	GOBP_Response_To_Radiation	Human	Intestine	A3	6.3e-07
PCNA	GOBP_Response_To_Steroid_Hormone	Human	Intestine	A3	2.1e-13
PCNA	GOBP_Response_To_Uv	Human	Intestine	A3	1.2e-08
PCNA	GOBP_Response_To_Xenobiotic_Stimulus	Human	Intestine	A3	2.5e-09
PCNA	GOBP_Rhythmic_Process	Human	Intestine	A3	4.4e-12
PCNA	GOBP_Base_Excision_Repair_Gap_Filling	Human	Intestine	A8	9.0e-08
PCNA	GOBP_Cell_Cycle_G1_S_Phase_Transition	Human	Intestine	A8	8.5e-07
PCNA	GOBP_Cellular_Homeostasis	Human	Intestine	A8	2.1e-11
PCNA	GOBP_Cellular_Response_To_Abiotic_Stimulus	Human	Intestine	A8	2.5e-11
PCNA	GOBP_Cellular_Response_To_Hydrogen_Peroxide	Human	Intestine	A8	5.2e-21
PCNA	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
PCNA	GOBP_Cellular_Response_To_Reactive_Oxygen_Species	Human	Intestine	A8	4.8e-25
PCNA	GOBP_Detection_Of_Stimulus	Human	Intestine	A8	2.4e-11
PCNA	GOBP_Dna_Damage_Response_Signal_Transduction_By_P53_Class_Mediator	Human	Intestine	A8	2.8e-10
PCNA	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Human	Intestine	A8	6.7e-17
PCNA	GOBP_Dna_Strand_Elongation_Involved_In_Dna_Replication	Human	Intestine	A8	6.2e-13
PCNA	GOBP_Dna_Synthesis_Involved_In_Dna_Repair	Human	Intestine	A8	9.2e-15
PCNA	GOBP_Epithelial_Cell_Differentiation	Human	Intestine	A8	6.8e-07
PCNA	GOBP_Error_Free_Translesion_Synthesis	Human	Intestine	A8	2.0e-13
PCNA	GOBP_Error_Prone_Translesion_Synthesis	Human	Intestine	A8	7.1e-15
PCNA	GOBP_Estrous_Cycle	Human	Intestine	A8	4.4e-11
PCNA	GOBP_Mismatch_Repair	Human	Intestine	A8	3.0e-08
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle	Human	Intestine	A8	3.1e-14
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_G1_S_Phase_Transition	Human	Intestine	A8	2.1e-11
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A8	4.4e-08
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A8	6.5e-12
PCNA	GOBP_Negative_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A8	5.4e-15
PCNA	GOBP_Nucleotide_Excision_Repair_Dna_Gap_Filling	Human	Intestine	A8	3.8e-18
PCNA	GOBP_Nucleotide_Excision_Repair_Dna_Incision	Human	Intestine	A8	8.6e-16
PCNA	GOBP_Positive_Regulation_Of_Dna_Replication	Human	Intestine	A8	2.2e-08
PCNA	GOBP_Postreplication_Repair	Human	Intestine	A8	3.3e-07
PCNA	GOBP_Regulation_Of_Dna_Biosynthetic_Process	Human	Intestine	A8	1.2e-08
PCNA	GOBP_Regulation_Of_Dna_Directed_Dna_Polymerase_Activity	Human	Intestine	A8	8.7e-09
PCNA	GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Intestine	A8	8.0e-07
PCNA	GOBP_Replication_Fork_Processing	Human	Intestine	A8	8.0e-11
PCNA	GOBP_Response_To_Acid_Chemical	Human	Intestine	A8	9.3e-09
PCNA	GOBP_Response_To_Cadmium_Ion	Human	Intestine	A8	2.1e-09
PCNA	GOBP_Response_To_Corticosteroid	Human	Intestine	A8	4.4e-19
PCNA	GOBP_Response_To_Dexamethasone	Human	Intestine	A8	1.4e-12
PCNA	GOBP_Response_To_Hormone	Human	Intestine	A8	2.3e-13
PCNA	GOBP_Response_To_Hydrogen_Peroxide	Human	Intestine	A8	7.1e-08
PCNA	GOBP_Response_To_Ketone	Human	Intestine	A8	1.1e-27
PCNA	GOBP_Response_To_Metal_Ion	Human	Intestine	A8	2.1e-21
PCNA	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
PCNA	GOBP_Response_To_Reactive_Oxygen_Species	Human	Intestine	A8	1.4e-28
PCNA	GOBP_Telomere_Maintenance_Via_Semi_Conservative_Replication	Human	Intestine	A8	1.5e-08
PCNA	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Human	Intestine	A8	3.5e-07
PCNA	GOBP_Translesion_Synthesis	Human	Intestine	A8	3.1e-13
PCNA	GOBP_Animal_Organ_Regeneration	Human	Pancreas	PDAC-B-st1	2.9e-05
PCNA	GOBP_Ovulation_Cycle	Human	Pancreas	PDAC-B-st1	3.6e-05
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Pancreas	PDAC-B-st1	4.0e-05
PCNA	GOBP_Regeneration	Human	Pancreas	PDAC-B-st1	6.7e-06
PCNA	GOBP_Regulation_Of_Dna_Dependent_Dna_Replication	Human	Pancreas	PDAC-B-st1	5.8e-06
PCNA	GOBP_Response_To_Hydrogen_Peroxide	Human	Pancreas	PDAC-B-st1	7.1e-05
PCNA	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Human	Pancreas	PDAC-B-st1	4.0e-06
PCNA	GOBP_Error_Free_Translesion_Synthesis	Human	Pancreas	PDAC-A-st2	3.9e-05
PCNA	GOBP_Error_Prone_Translesion_Synthesis	Human	Pancreas	PDAC-A-st2	5.4e-05
PCNA	GOBP_Mismatch_Repair	Human	Pancreas	PDAC-A-st2	3.1e-05
PCNA	GOBP_Nucleotide_Excision_Repair	Human	Pancreas	PDAC-A-st2	4.7e-06
PCNA	GOBP_Replication_Fork_Processing	Human	Pancreas	PDAC-A-st2	2.6e-05
PCNA	GOBP_Telomere_Maintenance_Via_Semi_Conservative_Replication	Human	Pancreas	PDAC-A-st2	1.9e-06
PCNA	GOBP_Anatomical_Structure_Homeostasis	Human	Uterus	rep_1	8.8e-07
PCNA	GOBP_Error_Prone_Translesion_Synthesis	Human	Uterus	rep_1	7.0e-06
PCNA	GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_1	1.2e-08
PCNA	GOBP_Signal_Transduction_By_P53_Class_Mediator	Human	Uterus	rep_1	3.7e-07
PCNA	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Human	Uterus	rep_1	2.3e-08
PCNA	GOBP_Dna_Strand_Elongation	Human	Uterus	rep_25	4.6e-11
PCNA	GOBP_Dna_Synthesis_Involved_In_Dna_Repair	Human	Uterus	rep_25	1.3e-10
PCNA	GOBP_Nucleotide_Excision_Repair_Dna_Gap_Filling	Human	Uterus	rep_25	6.0e-10
PCNA	GOBP_Positive_Regulation_Of_Deoxyribonuclease_Activity	Human	Uterus	rep_25	4.1e-15
PCNA	GOBP_Postreplication_Repair	Human	Uterus	rep_25	5.2e-06
PCNA	GOBP_Regulation_Of_Deoxyribonuclease_Activity	Human	Uterus	rep_25	7.3e-24
PCNA	GOBP_Regulation_Of_Dna_Directed_Dna_Polymerase_Activity	Human	Uterus	rep_25	1.5e-06
PCNA	GOBP_Translesion_Synthesis	Human	Uterus	rep_25	4.9e-06
PCNA	GOBP_Base_Excision_Repair	Human	Uterus	rep_26	9.9e-06
PCNA	GOBP_Base_Excision_Repair_Gap_Filling	Human	Uterus	rep_26	6.6e-15
PCNA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
PCNA	GOBP_Cell_Cycle_Dna_Replication	Human	Uterus	rep_26	3.2e-07
PCNA	GOBP_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	1.9e-06
PCNA	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_26	2.4e-07
PCNA	GOBP_Cellular_Response_To_Uv	Human	Uterus	rep_26	6.2e-07
PCNA	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
PCNA	GOBP_Dna_Dependent_Dna_Replication	Human	Uterus	rep_26	2.7e-14
PCNA	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Human	Uterus	rep_26	1.4e-08
PCNA	GOBP_Dna_Replication	Human	Uterus	rep_26	1.5e-09
PCNA	GOBP_Estrous_Cycle	Human	Uterus	rep_26	1.8e-15
PCNA	GOBP_Gland_Development	Human	Uterus	rep_26	1.6e-07
PCNA	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	1.0e-08
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	8.1e-09
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_Process	Human	Uterus	rep_26	2.4e-12
PCNA	GOBP_Negative_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	1.3e-08
PCNA	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
PCNA	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Uterus	rep_26	6.2e-13
PCNA	GOBP_Nucleotide_Excision_Repair	Human	Uterus	rep_26	1.3e-07
PCNA	GOBP_Nucleotide_Excision_Repair_Dna_Incision	Human	Uterus	rep_26	8.0e-09
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	2.1e-09
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Uterus	rep_26	1.2e-15
PCNA	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Uterus	rep_26	2.8e-06
PCNA	GOBP_Positive_Regulation_Of_Dna_Replication	Human	Uterus	rep_26	3.8e-15
PCNA	GOBP_Positive_Regulation_Of_Nuclease_Activity	Human	Uterus	rep_26	8.3e-06
PCNA	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Uterus	rep_26	2.1e-08
PCNA	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	5.7e-08
PCNA	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	9.3e-07
PCNA	GOBP_Regulation_Of_Dna_Dependent_Dna_Replication	Human	Uterus	rep_26	2.3e-09
PCNA	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
PCNA	GOBP_Regulation_Of_Dna_Replication	Human	Uterus	rep_26	1.5e-08
PCNA	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
PCNA	GOBP_Regulation_Of_Nuclease_Activity	Human	Uterus	rep_26	1.2e-08
PCNA	GOBP_Response_To_Dexamethasone	Human	Uterus	rep_26	6.8e-07
PCNA	GOBP_Response_To_Reactive_Oxygen_Species	Human	Uterus	rep_26	2.1e-12
PCNA	GOBP_Response_To_Uv	Human	Uterus	rep_26	1.4e-06
PCNA	GOBP_Signal_Transduction_In_Response_To_Dna_Damage	Human	Uterus	rep_26	6.1e-08
PCNA	GOBP_Error_Free_Translesion_Synthesis	Human	Uterus	rep_27	2.3e-07
PCNA	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
PCNA	GOBP_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_29	9.2e-06
PCNA	GOBP_Response_To_Corticosteroid	Human	Uterus	rep_29	4.7e-06
PCNA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
PCNA	GOBP_Cellular_Homeostasis	Human	Breast	rep_1	2.8e-10
PCNA	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
PCNA	GOBP_Detection_Of_Stimulus	Human	Breast	rep_1	1.8e-04
PCNA	GOBP_Epithelial_Cell_Differentiation	Human	Breast	rep_1	4.5e-30
PCNA	GOBP_Epithelium_Development	Human	Breast	rep_1	2.0e-22
PCNA	GOBP_Error_Prone_Translesion_Synthesis	Human	Breast	rep_1	3.9e-08
PCNA	GOBP_Gland_Development	Human	Breast	rep_1	2.0e-26
PCNA	GOBP_Heart_Development	Human	Breast	rep_1	4.1e-08
PCNA	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
PCNA	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
PCNA	GOBP_Regeneration	Human	Breast	rep_1	2.9e-06
PCNA	GOBP_Regulation_Of_Response_To_Stress	Human	Breast	rep_1	3.4e-19
PCNA	GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Breast	rep_1	1.6e-31
PCNA	GOBP_Response_To_Abiotic_Stimulus	Human	Breast	rep_1	2.6e-19
PCNA	GOBP_Response_To_Acid_Chemical	Human	Breast	rep_1	8.2e-09
PCNA	GOBP_Response_To_Corticosteroid	Human	Breast	rep_1	1.5e-56
PCNA	GOBP_Response_To_Metal_Ion	Human	Breast	rep_1	3.0e-20
PCNA	GOBP_Error_Free_Translesion_Synthesis	Human	Breast	rep_4	9.2e-08
PCNA	GOBP_Cellular_Response_To_Abiotic_Stimulus	Human	Breast	rep_5	1.3e-06
PCNA	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
PCNA	GOBP_Multicellular_Organism_Reproduction	Human	Breast	rep_5	8.1e-07
PCNA	GOBP_Nucleotide_Excision_Repair_Dna_Incision	Human	Breast	rep_5	5.5e-07
PCNA	GOBP_Ovulation_Cycle	Human	Breast	rep_5	2.5e-18
PCNA	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
PCNA	GOBP_Positive_Regulation_Of_Dna_Repair	Human	Breast	rep_5	1.4e-04
PCNA	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
PCNA	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
PCNA	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
PCNA	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Breast	rep_5	8.1e-10
PCNA	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
PCNA	GOBP_Reproduction	Human	Breast	rep_5	8.1e-06
PCNA	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
PCNA	GOBP_Response_To_Estradiol	Human	Breast	rep_5	6.9e-16
PCNA	GOBP_Response_To_Hormone	Human	Breast	rep_5	2.9e-13
PCNA	GOBP_Response_To_Inorganic_Substance	Human	Breast	rep_5	1.8e-10
PCNA	GOBP_Response_To_Ketone	Human	Breast	rep_5	3.5e-14
PCNA	GOBP_Response_To_L_Glutamate	Human	Breast	rep_5	2.7e-16
PCNA	GOBP_Response_To_Lipid	Human	Breast	rep_5	1.6e-10
PCNA	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
PCNA	GOBP_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	7.5e-14
PCNA	GOBP_Response_To_Oxidative_Stress	Human	Breast	rep_5	1.0e-04
PCNA	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
PCNA	GOBP_Response_To_Radiation	Human	Breast	rep_5	3.8e-06
PCNA	GOBP_Response_To_Steroid_Hormone	Human	Breast	rep_5	4.5e-13
PCNA	GOBP_Response_To_Xenobiotic_Stimulus	Human	Breast	rep_5	2.9e-05
PCNA	GOBP_Animal_Organ_Regeneration	Human	Breast	rep_6	1.9e-10
PCNA	GOBP_Base_Excision_Repair	Human	Breast	rep_6	1.1e-05
PCNA	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
PCNA	GOBP_Cell_Cycle_G1_S_Phase_Transition	Human	Breast	rep_6	3.5e-11
PCNA	GOBP_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	4.9e-09
PCNA	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
PCNA	GOBP_Cellular_Response_To_Chemical_Stress	Human	Breast	rep_6	3.6e-05
PCNA	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	6.0e-06
PCNA	GOBP_Cellular_Response_To_Hydrogen_Peroxide	Human	Breast	rep_6	2.8e-05
PCNA	GOBP_Cellular_Response_To_Radiation	Human	Breast	rep_6	5.1e-06
PCNA	GOBP_Cellular_Response_To_Reactive_Oxygen_Species	Human	Breast	rep_6	1.3e-05
PCNA	GOBP_Cellular_Response_To_Uv	Human	Breast	rep_6	4.9e-05
PCNA	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
PCNA	GOBP_Dna_Biosynthetic_Process	Human	Breast	rep_6	5.0e-13
PCNA	GOBP_Dna_Dependent_Dna_Replication	Human	Breast	rep_6	5.7e-04
PCNA	GOBP_Dna_Metabolic_Process	Human	Breast	rep_6	1.4e-10
PCNA	GOBP_Dna_Repair	Human	Breast	rep_6	1.0e-09
PCNA	GOBP_Dna_Replication	Human	Breast	rep_6	3.5e-07
PCNA	GOBP_Dna_Synthesis_Involved_In_Dna_Repair	Human	Breast	rep_6	3.5e-07
PCNA	GOBP_Hepaticobiliary_System_Development	Human	Breast	rep_6	1.5e-07
PCNA	GOBP_Liver_Regeneration	Human	Breast	rep_6	9.3e-15
PCNA	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
PCNA	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Breast	rep_6	2.6e-08
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	5.3e-11
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_G1_S_Phase_Transition	Human	Breast	rep_6	1.1e-11
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	9.1e-12
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	2.3e-13
PCNA	GOBP_Negative_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	1.5e-13
PCNA	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
PCNA	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	8.2e-08
PCNA	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Human	Breast	rep_6	2.6e-05
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	7.0e-10
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	7.5e-09
PCNA	GOBP_Positive_Regulation_Of_Deoxyribonuclease_Activity	Human	Breast	rep_6	1.2e-07
PCNA	GOBP_Positive_Regulation_Of_Dna_Biosynthetic_Process	Human	Breast	rep_6	1.1e-07
PCNA	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Breast	rep_6	2.4e-08
PCNA	GOBP_Positive_Regulation_Of_Dna_Replication	Human	Breast	rep_6	9.0e-09
PCNA	GOBP_Positive_Regulation_Of_Nuclease_Activity	Human	Breast	rep_6	5.3e-05
PCNA	GOBP_Positive_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	3.8e-06
PCNA	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	3.2e-05
PCNA	GOBP_Postreplication_Repair	Human	Breast	rep_6	6.3e-06
PCNA	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Breast	rep_6	3.6e-10
PCNA	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	2.7e-09
PCNA	GOBP_Regulation_Of_Cell_Cycle_G1_S_Phase_Transition	Human	Breast	rep_6	2.8e-06
PCNA	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	2.7e-07
PCNA	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
PCNA	GOBP_Regulation_Of_Deoxyribonuclease_Activity	Human	Breast	rep_6	2.7e-08
PCNA	GOBP_Regulation_Of_Dna_Biosynthetic_Process	Human	Breast	rep_6	4.0e-08
PCNA	GOBP_Regulation_Of_Dna_Dependent_Dna_Replication	Human	Breast	rep_6	2.1e-08
PCNA	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Breast	rep_6	9.5e-08
PCNA	GOBP_Regulation_Of_Dna_Repair	Human	Breast	rep_6	1.1e-08
PCNA	GOBP_Regulation_Of_Dna_Replication	Human	Breast	rep_6	1.8e-08
PCNA	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
PCNA	GOBP_Regulation_Of_Nuclease_Activity	Human	Breast	rep_6	2.5e-06
PCNA	GOBP_Regulation_Of_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	7.4e-06
PCNA	GOBP_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	4.6e-05
PCNA	GOBP_Replication_Fork_Processing	Human	Breast	rep_6	6.2e-04
PCNA	GOBP_Response_To_Cadmium_Ion	Human	Breast	rep_6	7.8e-04
PCNA	GOBP_Response_To_Hydrogen_Peroxide	Human	Breast	rep_6	6.6e-04
PCNA	GOBP_Response_To_Light_Stimulus	Human	Breast	rep_6	1.5e-09
PCNA	GOBP_Response_To_Uv	Human	Breast	rep_6	5.2e-08
PCNA	GOBP_Rhythmic_Process	Human	Breast	rep_6	1.0e-11
PCNA	GOBP_Signal_Transduction_By_P53_Class_Mediator	Human	Breast	rep_6	7.7e-05
PCNA	GOBP_Signal_Transduction_In_Response_To_Dna_Damage	Human	Breast	rep_6	1.7e-07
PCNA	GOBP_Telomere_Organization	Human	Breast	rep_6	6.0e-08
PCNA	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Human	Breast	rep_6	2.3e-11
PCNA	GOBP_Regeneration	Human	Skin	P2_rep2	5.2e-08
PCNA	GOBP_Response_To_Cadmium_Ion	Human	Skin	P2_rep2	2.1e-08
PCNA	GOBP_Dna_Repair	Human	Skin	P5_rep1	1.7e-08
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Skin	P5_rep1	7.8e-10
PCNA	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Skin	P5_rep1	4.9e-14
PCNA	GOBP_Response_To_Light_Stimulus	Human	Skin	P5_rep1	4.5e-08
PCNA	GOBP_Error_Free_Translesion_Synthesis	Human	Skin	P5_rep3	7.6e-08
PCNA	GOBP_Negative_Regulation_Of_Cell_Cycle_Process	Human	Skin	P5_rep3	1.1e-11
PCNA	GOBP_Nucleotide_Excision_Repair_Dna_Gap_Filling	Human	Skin	P5_rep3	1.5e-23
PCNA	GOBP_Positive_Regulation_Of_Dna_Replication	Human	Skin	P5_rep3	3.5e-09
PCNA	GOBP_Regulation_Of_Dna_Dependent_Dna_Replication	Human	Skin	P5_rep3	4.0e-08
PCNA	GOBP_Response_To_L_Glutamate	Human	Skin	P5_rep3	5.2e-18
PCNA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
PCNA	GOBP_Epithelium_Development	Human	Skin	P9_rep3	4.2e-08
PCNA	GOBP_Error_Prone_Translesion_Synthesis	Human	Skin	P10_rep1	1.6e-12
PCNA	GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Skin	P10_rep1	2.5e-16
PCNA	GOBP_Replication_Fork_Processing	Human	Skin	P10_rep1	7.6e-08
PCNA	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Human	Skin	P10_rep1	1.1e-08
PCNA	GOBP_Translesion_Synthesis	Human	Skin	P10_rep1	2.6e-08
PCNA	GOBP_Base_Excision_Repair_Gap_Filling	Human	Skin	P10_rep2	3.5e-08
PCNA	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Human	Skin	P10_rep2	1.3e-28
PCNA	GOBP_Dna_Synthesis_Involved_In_Dna_Repair	Human	Skin	P10_rep2	2.5e-11
PCNA	GOBP_Mismatch_Repair	Human	Skin	P10_rep2	2.2e-10
PCNA	GOBP_Nucleotide_Excision_Repair_Dna_Incision	Human	Skin	P10_rep2	4.7e-09
PCNA	GOBP_Telomere_Maintenance_Via_Semi_Conservative_Replication	Human	Skin	P10_rep2	1.7e-09
PCNA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
PCNA	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
PCNA	GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle	Human	Lung	rep_1	2.1e-07
PCNA	GOBP_Response_To_Lipid	Human	Lung	rep_1	1.8e-09
PCNA	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08
PCNA	GOBP_Cellular_Homeostasis	Human	Lung	rep_2	7.3e-07
PCNA	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07

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PCNA function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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PCNA function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for PCNA envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for PCNA

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
PCNA	P12004	DB00279	Liothyronine	Proliferating cell nuclear antigen	SmallMoleculeDrug	approved\|vet_approved
PCNA	P12004	DB00945	Acetylsalicylic acid	Proliferating cell nuclear antigen	SmallMoleculeDrug	approved\|vet_approved

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Related Diseases for PCNA

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
PCNA	C0007102	Malignant tumor of colon	2	CTD_human
PCNA	C0009375	Colonic Neoplasms	2	CTD_human
PCNA	C0001418	Adenocarcinoma	1	CTD_human
PCNA	C0006118	Brain Neoplasms	1	CTD_human
PCNA	C0017668	Focal glomerulosclerosis	1	CTD_human
PCNA	C0022116	Ischemia	1	CTD_human
PCNA	C0024121	Lung Neoplasms	1	CTD_human
PCNA	C0027659	Neoplasms, Experimental	1	CTD_human
PCNA	C0030246	Pustulosis of Palms and Soles	1	CTD_human
PCNA	C0033860	Psoriasis	1	CTD_human
PCNA	C0086432	Hyalinosis, Segmental Glomerular	1	CTD_human
PCNA	C0153633	Malignant neoplasm of brain	1	CTD_human
PCNA	C0205641	Adenocarcinoma, Basal Cell	1	CTD_human
PCNA	C0205642	Adenocarcinoma, Oxyphilic	1	CTD_human
PCNA	C0205643	Carcinoma, Cribriform	1	CTD_human
PCNA	C0205644	Carcinoma, Granular Cell	1	CTD_human
PCNA	C0205645	Adenocarcinoma, Tubular	1	CTD_human
PCNA	C0206624	Hepatoblastoma	1	CTD_human
PCNA	C0242379	Malignant neoplasm of lung	1	CTD_human
PCNA	C0496899	Benign neoplasm of brain, unspecified	1	CTD_human
PCNA	C0750974	Brain Tumor, Primary	1	CTD_human
PCNA	C0750977	Recurrent Brain Neoplasm	1	CTD_human
PCNA	C0750979	Primary malignant neoplasm of brain	1	CTD_human
PCNA	C1527390	Neoplasms, Intracranial	1	CTD_human
PCNA	C4014676	ATAXIA-TELANGIECTASIA-LIKE DISORDER 2	1	ORPHANET;UNIPROT