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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: PCK2 (spascer ID:5106)

Gene summary for PCK2

Gene summary

Gene information
	Species	Human
	Gene symbol	PCK2
	Gene ID	5106
	Gene name	phosphoenolpyruvate carboxykinase 2, mitochondrial
	Synonyms	PEPCK\|PEPCK-M\|PEPCK2
	Cytomap	14q11.2-q12
	Type of gene	protein-coding
	Description	phosphoenolpyruvate carboxykinase [GTP], mitochondrialPEP carboxykinaseepididymis secretory sperm binding proteinphosphopyruvate carboxylase
	Modification date	20220513
	UniProtAcc	Q16822

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
PCK2	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	21873635	Function
PCK2	GO:0005739	mitochondrion	21873635	Component
PCK2	GO:0005829	cytosol	21873635	Component
PCK2	GO:0006094	gluconeogenesis	21873635	Process
PCK2	GO:0019543	propionate catabolic process	21873635	Process
PCK2	GO:0030145	manganese ion binding	21873635	Function
PCK2	GO:0032869	cellular response to insulin stimulus	21873635	Process
PCK2	GO:0033993	response to lipid	21873635	Process
PCK2	GO:0042594	response to starvation	21873635	Process
PCK2	GO:0046327	glycerol biosynthetic process from pyruvate	21873635	Process
PCK2	GO:0070365	hepatocyte differentiation	21873635	Process
PCK2	GO:0071333	cellular response to glucose stimulus	21873635	Process
PCK2	GO:0071549	cellular response to dexamethasone stimulus	21873635	Process

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Spatial pattern events for PCK2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
PCK2	Human	Intestine	rep_colon1	34417225	5.56e-07
PCK2	Human	Intestine	rep_colon4	34417225	1.14e-15
PCK2	Human	Liver	rep_liver1	34417225	1.08e-15
PCK2	Human	Liver	rep_liver2	34417225	6.98e-16
PCK2	Human	Liver	rep_liver3	34417225	2.96e-12
PCK2	Human	Liver	rep_liver4	34417225	7.71e-16
PCK2	Human	Intestine	A4	33406409	9.63e-15
PCK2	Human	Intestine	A6	33406409	5.29e-06
PCK2	Human	Intestine	A7	33406409	1.59e-06
PCK2	Human	Intestine	A8	33406409	2.82e-14
PCK2	Human	Intestine	A9	33406409	2.34e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E
Intestine_A4_H&E
Intestine_A6_H&E
Intestine_A7_H&E
Intestine_A8_H&E
Intestine_A9_H&E

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Spatial pattern pathway has PCK2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
PCK2	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
PCK2	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
PCK2	GOBP_Positive_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
PCK2	GOBP_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
PCK2	GOBP_Response_To_Bacterium	Human	Brain	rep_1	3.1e-16
PCK2	GOBP_Regulation_Of_Protein_Localization	Human	Brain	rep_4	1.0e-14
PCK2	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
PCK2	GOBP_Response_To_Hormone	Human	Brain	rep_10	2.8e-23
PCK2	GOBP_Response_To_Lipid	Human	Brain	rep_10	2.8e-23
PCK2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
PCK2	GOBP_Response_To_Extracellular_Stimulus	Human	Brain	rep_11	2.5e-12
PCK2	GOBP_Response_To_Ketone	Human	Brain	rep_11	2.5e-12
PCK2	GOBP_Response_To_Corticosteroid	Human	Bladder	rep_2	3.3e-18
PCK2	GOBP_Response_To_Peptide	Human	Bladder	rep_2	2.3e-11
PCK2	GOBP_Response_To_Peptide_Hormone	Human	Bladder	rep_2	2.9e-13
PCK2	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
PCK2	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
PCK2	GOBP_Positive_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
PCK2	GOBP_Regulation_Of_Protein_Localization	Human	Liver	rep_1	2.1e-52
PCK2	GOBP_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
PCK2	GOBP_Response_To_Bacterium	Human	Liver	rep_1	9.4e-68
PCK2	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
PCK2	GOBP_Response_To_Extracellular_Stimulus	Human	Liver	rep_1	1.7e-73
PCK2	GOBP_Response_To_Hormone	Human	Liver	rep_1	3.0e-55
PCK2	GOBP_Response_To_Ketone	Human	Liver	rep_1	1.7e-73
PCK2	GOBP_Response_To_Lipid	Human	Liver	rep_1	3.0e-55
PCK2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
PCK2	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	rep_colon2	1.5e-57
PCK2	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
PCK2	GOBP_Positive_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
PCK2	GOBP_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
PCK2	GOBP_Response_To_Bacterium	Human	Intestine	rep_colon4	1.0e-26
PCK2	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
PCK2	GOBP_Response_To_Extracellular_Stimulus	Human	Intestine	rep_liver2	8.9e-16
PCK2	GOBP_Response_To_Hormone	Human	Intestine	rep_liver2	3.7e-39
PCK2	GOBP_Response_To_Ketone	Human	Intestine	rep_liver2	8.9e-16
PCK2	GOBP_Response_To_Lipid	Human	Intestine	rep_liver2	3.7e-39
PCK2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
PCK2	GOBP_Carbohydrate_Biosynthetic_Process	Human	Intestine	A3	5.4e-08
PCK2	GOBP_Carbohydrate_Homeostasis	Human	Intestine	A3	5.3e-08
PCK2	GOBP_Carbohydrate_Metabolic_Process	Human	Intestine	A3	4.1e-08
PCK2	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
PCK2	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Intestine	A3	3.9e-07
PCK2	GOBP_Cellular_Glucose_Homeostasis	Human	Intestine	A3	3.3e-11
PCK2	GOBP_Cellular_Response_To_Carbohydrate_Stimulus	Human	Intestine	A3	1.0e-10
PCK2	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Intestine	A3	8.7e-19
PCK2	GOBP_Cellular_Response_To_Insulin_Stimulus	Human	Intestine	A3	4.8e-16
PCK2	GOBP_Cellular_Response_To_Lipid	Human	Intestine	A3	7.7e-08
PCK2	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	2.5e-14
PCK2	GOBP_Cellular_Response_To_Peptide_Hormone_Stimulus	Human	Intestine	A3	4.0e-16
PCK2	GOBP_Cellular_Response_To_Steroid_Hormone_Stimulus	Human	Intestine	A3	5.6e-26
PCK2	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
PCK2	GOBP_Gland_Development	Human	Intestine	A3	2.3e-14
PCK2	GOBP_Hepaticobiliary_System_Development	Human	Intestine	A3	1.6e-07
PCK2	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
PCK2	GOBP_Lipid_Biosynthetic_Process	Human	Intestine	A3	5.0e-07
PCK2	GOBP_Positive_Regulation_Of_Establishment_Of_Protein_Localization	Human	Intestine	A3	1.8e-09
PCK2	GOBP_Positive_Regulation_Of_Secretion	Human	Intestine	A3	8.5e-10
PCK2	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
PCK2	GOBP_Positive_Regulation_Of_Transport	Human	Intestine	A3	9.5e-08
PCK2	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	A3	7.5e-08
PCK2	GOBP_Regulation_Of_Transport	Human	Intestine	A3	4.4e-11
PCK2	GOBP_Response_To_Carbohydrate	Human	Intestine	A3	1.8e-07
PCK2	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
PCK2	GOBP_Response_To_Insulin	Human	Intestine	A3	2.2e-15
PCK2	GOBP_Response_To_Lipid	Human	Intestine	A3	1.7e-09
PCK2	GOBP_Response_To_Monosaccharide	Human	Intestine	A3	1.4e-09
PCK2	GOBP_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	3.2e-15
PCK2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
PCK2	GOBP_Response_To_Steroid_Hormone	Human	Intestine	A3	2.1e-13
PCK2	GOBP_Response_To_Tumor_Necrosis_Factor	Human	Intestine	A3	2.5e-09
PCK2	GOBP_Secretion	Human	Intestine	A3	1.8e-13
PCK2	GOBP_Alcohol_Biosynthetic_Process	Human	Intestine	A8	5.3e-09
PCK2	GOBP_Alditol_Metabolic_Process	Human	Intestine	A8	3.6e-15
PCK2	GOBP_Cellular_Carbohydrate_Biosynthetic_Process	Human	Intestine	A8	1.6e-13
PCK2	GOBP_Cellular_Homeostasis	Human	Intestine	A8	2.1e-11
PCK2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Intestine	A8	3.8e-13
PCK2	GOBP_Cellular_Response_To_Corticosteroid_Stimulus	Human	Intestine	A8	1.6e-19
PCK2	GOBP_Cellular_Response_To_Dexamethasone_Stimulus	Human	Intestine	A8	2.1e-09
PCK2	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
PCK2	GOBP_Cellular_Response_To_Peptide	Human	Intestine	A8	2.9e-08
PCK2	GOBP_Chemical_Homeostasis	Human	Intestine	A8	1.3e-12
PCK2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	2.6e-15
PCK2	GOBP_Epithelial_Cell_Differentiation	Human	Intestine	A8	6.8e-07
PCK2	GOBP_Fatty_Acid_Catabolic_Process	Human	Intestine	A8	2.2e-14
PCK2	GOBP_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-13
PCK2	GOBP_Glucose_Metabolic_Process	Human	Intestine	A8	1.5e-21
PCK2	GOBP_Glycerolipid_Biosynthetic_Process	Human	Intestine	A8	1.4e-11
PCK2	GOBP_Glycerolipid_Metabolic_Process	Human	Intestine	A8	1.2e-09
PCK2	GOBP_Hepatocyte_Differentiation	Human	Intestine	A8	2.5e-10
PCK2	GOBP_Hormone_Transport	Human	Intestine	A8	5.8e-10
PCK2	GOBP_Insulin_Secretion	Human	Intestine	A8	1.2e-13
PCK2	GOBP_Lipid_Catabolic_Process	Human	Intestine	A8	3.2e-08
PCK2	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
PCK2	GOBP_Monocarboxylic_Acid_Catabolic_Process	Human	Intestine	A8	1.5e-10
PCK2	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
PCK2	GOBP_Monosaccharide_Biosynthetic_Process	Human	Intestine	A8	4.0e-16
PCK2	GOBP_Monosaccharide_Metabolic_Process	Human	Intestine	A8	4.7e-24
PCK2	GOBP_Nad_Metabolic_Process	Human	Intestine	A8	3.9e-11
PCK2	GOBP_Nadh_Metabolic_Process	Human	Intestine	A8	4.4e-14
PCK2	GOBP_Organic_Acid_Catabolic_Process	Human	Intestine	A8	1.6e-12
PCK2	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
PCK2	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Intestine	A8	1.2e-10
PCK2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Intestine	A8	6.4e-10
PCK2	GOBP_Oxaloacetate_Metabolic_Process	Human	Intestine	A8	4.9e-19
PCK2	GOBP_Polyol_Biosynthetic_Process	Human	Intestine	A8	1.3e-18
PCK2	GOBP_Polyol_Metabolic_Process	Human	Intestine	A8	6.2e-14
PCK2	GOBP_Positive_Regulation_Of_Hormone_Secretion	Human	Intestine	A8	5.9e-21
PCK2	GOBP_Positive_Regulation_Of_Insulin_Secretion	Human	Intestine	A8	7.6e-14
PCK2	GOBP_Positive_Regulation_Of_Ion_Transport	Human	Intestine	A8	1.1e-09
PCK2	GOBP_Positive_Regulation_Of_Peptide_Secretion	Human	Intestine	A8	5.5e-18
PCK2	GOBP_Pyruvate_Metabolic_Process	Human	Intestine	A8	1.4e-20
PCK2	GOBP_Regulation_Of_Anion_Transport	Human	Intestine	A8	2.7e-14
PCK2	GOBP_Regulation_Of_Hormone_Levels	Human	Intestine	A8	3.0e-13
PCK2	GOBP_Regulation_Of_Hormone_Secretion	Human	Intestine	A8	8.6e-18
PCK2	GOBP_Regulation_Of_Ion_Transport	Human	Intestine	A8	2.0e-13
PCK2	GOBP_Regulation_Of_Peptide_Transport	Human	Intestine	A8	1.3e-14
PCK2	GOBP_Regulation_Of_Secretion	Human	Intestine	A8	2.2e-15
PCK2	GOBP_Response_To_Bacterium	Human	Intestine	A8	3.3e-17
PCK2	GOBP_Response_To_Corticosteroid	Human	Intestine	A8	4.4e-19
PCK2	GOBP_Response_To_Cytokine	Human	Intestine	A8	1.6e-08
PCK2	GOBP_Response_To_Dexamethasone	Human	Intestine	A8	1.4e-12
PCK2	GOBP_Response_To_Extracellular_Stimulus	Human	Intestine	A8	2.1e-23
PCK2	GOBP_Response_To_Hormone	Human	Intestine	A8	2.3e-13
PCK2	GOBP_Response_To_Ketone	Human	Intestine	A8	1.1e-27
PCK2	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Human	Intestine	A8	1.0e-14
PCK2	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
PCK2	GOBP_Response_To_Peptide	Human	Intestine	A8	2.0e-09
PCK2	GOBP_Response_To_Peptide_Hormone	Human	Intestine	A8	3.4e-09
PCK2	GOBP_Response_To_Starvation	Human	Intestine	A8	6.6e-17
PCK2	GOBP_Short_Chain_Fatty_Acid_Catabolic_Process	Human	Intestine	A8	1.8e-09
PCK2	GOBP_Short_Chain_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	1.6e-09
PCK2	GOBP_Signal_Release	Human	Intestine	A8	6.9e-14
PCK2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
PCK2	GOBP_Small_Molecule_Catabolic_Process	Human	Intestine	A8	2.2e-13
PCK2	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
PCK2	GOBP_Alcohol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
PCK2	GOBP_Cellular_Response_To_Corticosteroid_Stimulus	Human	Pancreas	PDAC-B-st1	3.7e-05
PCK2	GOBP_Nadh_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
PCK2	GOBP_Polyol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.8e-06
PCK2	GOBP_Positive_Regulation_Of_Peptide_Secretion	Human	Pancreas	PDAC-B-st1	1.5e-05
PCK2	GOBP_Regulation_Of_Anion_Transport	Human	Pancreas	PDAC-B-st1	4.7e-06
PCK2	GOBP_Response_To_Starvation	Human	Pancreas	PDAC-B-st1	9.3e-06
PCK2	GOBP_Positive_Regulation_Of_Insulin_Secretion	Human	Pancreas	PDAC-A-st2	4.4e-07
PCK2	GOBP_Hepatocyte_Differentiation	Human	Uterus	rep_25	1.3e-13
PCK2	GOBP_Monosaccharide_Biosynthetic_Process	Human	Uterus	rep_25	6.0e-11
PCK2	GOBP_Nad_Metabolic_Process	Human	Uterus	rep_25	7.2e-08
PCK2	GOBP_Nadh_Oxidation	Human	Uterus	rep_25	1.1e-08
PCK2	GOBP_Oxaloacetate_Metabolic_Process	Human	Uterus	rep_25	5.0e-08
PCK2	GOBP_Positive_Regulation_Of_Anion_Transport	Human	Uterus	rep_25	3.2e-07
PCK2	GOBP_Regulation_Of_Anion_Transport	Human	Uterus	rep_25	1.5e-11
PCK2	GOBP_Short_Chain_Fatty_Acid_Catabolic_Process	Human	Uterus	rep_25	1.9e-13
PCK2	GOBP_Short_Chain_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_25	5.0e-12
PCK2	GOBP_Alcohol_Biosynthetic_Process	Human	Uterus	rep_26	2.6e-06
PCK2	GOBP_Alcohol_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
PCK2	GOBP_Alditol_Biosynthetic_Process	Human	Uterus	rep_26	1.3e-11
PCK2	GOBP_Alditol_Metabolic_Process	Human	Uterus	rep_26	6.9e-09
PCK2	GOBP_Carbohydrate_Biosynthetic_Process	Human	Uterus	rep_26	3.3e-14
PCK2	GOBP_Carbohydrate_Homeostasis	Human	Uterus	rep_26	1.4e-07
PCK2	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Uterus	rep_26	2.2e-06
PCK2	GOBP_Cellular_Lipid_Catabolic_Process	Human	Uterus	rep_26	4.6e-06
PCK2	GOBP_Cellular_Response_To_Carbohydrate_Stimulus	Human	Uterus	rep_26	6.9e-10
PCK2	GOBP_Cellular_Response_To_Corticosteroid_Stimulus	Human	Uterus	rep_26	5.2e-07
PCK2	GOBP_Cellular_Response_To_Steroid_Hormone_Stimulus	Human	Uterus	rep_26	9.7e-06
PCK2	GOBP_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
PCK2	GOBP_Gland_Development	Human	Uterus	rep_26	1.6e-07
PCK2	GOBP_Glucose_Metabolic_Process	Human	Uterus	rep_26	1.0e-15
PCK2	GOBP_Glycerolipid_Biosynthetic_Process	Human	Uterus	rep_26	9.1e-06
PCK2	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
PCK2	GOBP_Monocarboxylic_Acid_Catabolic_Process	Human	Uterus	rep_26	1.3e-10
PCK2	GOBP_Monosaccharide_Metabolic_Process	Human	Uterus	rep_26	2.7e-11
PCK2	GOBP_Nadh_Metabolic_Process	Human	Uterus	rep_26	5.2e-06
PCK2	GOBP_Organic_Acid_Catabolic_Process	Human	Uterus	rep_26	6.9e-09
PCK2	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
PCK2	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Uterus	rep_26	3.2e-10
PCK2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Uterus	rep_26	2.5e-08
PCK2	GOBP_Positive_Regulation_Of_Hormone_Secretion	Human	Uterus	rep_26	5.2e-07
PCK2	GOBP_Positive_Regulation_Of_Insulin_Secretion	Human	Uterus	rep_26	1.6e-10
PCK2	GOBP_Pyruvate_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
PCK2	GOBP_Regulation_Of_Secretion	Human	Uterus	rep_26	1.7e-06
PCK2	GOBP_Response_To_Dexamethasone	Human	Uterus	rep_26	6.8e-07
PCK2	GOBP_Response_To_Extracellular_Stimulus	Human	Uterus	rep_26	1.1e-14
PCK2	GOBP_Response_To_Monosaccharide	Human	Uterus	rep_26	2.0e-06
PCK2	GOBP_Response_To_Tumor_Necrosis_Factor	Human	Uterus	rep_26	1.5e-09
PCK2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
PCK2	GOBP_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	9.1e-13
PCK2	GOBP_Triglyceride_Biosynthetic_Process	Human	Uterus	rep_26	2.4e-06
PCK2	GOBP_Response_To_Bacterium	Human	Uterus	rep_28	3.0e-06
PCK2	GOBP_Cellular_Glucose_Homeostasis	Human	Uterus	rep_29	3.8e-07
PCK2	GOBP_Glycerolipid_Metabolic_Process	Human	Uterus	rep_29	5.7e-07
PCK2	GOBP_Hormone_Transport	Human	Uterus	rep_29	6.3e-07
PCK2	GOBP_Insulin_Secretion	Human	Uterus	rep_29	3.7e-08
PCK2	GOBP_Neutral_Lipid_Metabolic_Process	Human	Uterus	rep_29	2.0e-09
PCK2	GOBP_Positive_Regulation_Of_Peptide_Secretion	Human	Uterus	rep_29	1.6e-16
PCK2	GOBP_Regulation_Of_Hormone_Secretion	Human	Uterus	rep_29	1.1e-09
PCK2	GOBP_Regulation_Of_Peptide_Transport	Human	Uterus	rep_29	1.2e-06
PCK2	GOBP_Response_To_Corticosteroid	Human	Uterus	rep_29	4.7e-06
PCK2	GOBP_Triglyceride_Metabolic_Process	Human	Uterus	rep_29	1.9e-07
PCK2	GOBP_Cellular_Homeostasis	Human	Breast	rep_1	2.8e-10
PCK2	GOBP_Cellular_Response_To_Carbohydrate_Stimulus	Human	Breast	rep_1	2.0e-12
PCK2	GOBP_Cellular_Response_To_Corticosteroid_Stimulus	Human	Breast	rep_1	5.0e-06
PCK2	GOBP_Cellular_Response_To_Ketone	Human	Breast	rep_1	8.9e-05
PCK2	GOBP_Chemical_Homeostasis	Human	Breast	rep_1	4.8e-18
PCK2	GOBP_Epithelial_Cell_Differentiation	Human	Breast	rep_1	4.5e-30
PCK2	GOBP_Epithelium_Development	Human	Breast	rep_1	2.0e-22
PCK2	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
PCK2	GOBP_Gland_Development	Human	Breast	rep_1	2.0e-26
PCK2	GOBP_Glycerolipid_Biosynthetic_Process	Human	Breast	rep_1	2.0e-10
PCK2	GOBP_Hepatocyte_Differentiation	Human	Breast	rep_1	6.4e-38
PCK2	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
PCK2	GOBP_Hormone_Transport	Human	Breast	rep_1	5.1e-85
PCK2	GOBP_Insulin_Secretion	Human	Breast	rep_1	1.9e-24
PCK2	GOBP_Monocarboxylic_Acid_Catabolic_Process	Human	Breast	rep_1	5.8e-04
PCK2	GOBP_Nadh_Oxidation	Human	Breast	rep_1	5.5e-04
PCK2	GOBP_Neutral_Lipid_Metabolic_Process	Human	Breast	rep_1	3.3e-15
PCK2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Breast	rep_1	7.3e-16
PCK2	GOBP_Positive_Regulation_Of_Hormone_Secretion	Human	Breast	rep_1	1.5e-09
PCK2	GOBP_Positive_Regulation_Of_Transport	Human	Breast	rep_1	3.1e-10
PCK2	GOBP_Regulation_Of_Hormone_Levels	Human	Breast	rep_1	1.1e-80
PCK2	GOBP_Regulation_Of_Hormone_Secretion	Human	Breast	rep_1	2.0e-64
PCK2	GOBP_Regulation_Of_Ion_Transport	Human	Breast	rep_1	1.7e-09
PCK2	GOBP_Regulation_Of_Peptide_Transport	Human	Breast	rep_1	7.5e-04
PCK2	GOBP_Regulation_Of_Protein_Localization	Human	Breast	rep_1	2.8e-21
PCK2	GOBP_Regulation_Of_Secretion	Human	Breast	rep_1	1.1e-10
PCK2	GOBP_Regulation_Of_Transport	Human	Breast	rep_1	3.7e-17
PCK2	GOBP_Response_To_Carbohydrate	Human	Breast	rep_1	3.1e-80
PCK2	GOBP_Response_To_Corticosteroid	Human	Breast	rep_1	1.5e-56
PCK2	GOBP_Response_To_Cytokine	Human	Breast	rep_1	2.5e-24
PCK2	GOBP_Response_To_Insulin	Human	Breast	rep_1	5.1e-04
PCK2	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Human	Breast	rep_1	1.2e-20
PCK2	GOBP_Response_To_Monosaccharide	Human	Breast	rep_1	3.0e-61
PCK2	GOBP_Response_To_Peptide_Hormone	Human	Breast	rep_1	2.0e-36
PCK2	GOBP_Response_To_Tumor_Necrosis_Factor	Human	Breast	rep_1	1.7e-52
PCK2	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
PCK2	GOBP_Triglyceride_Biosynthetic_Process	Human	Breast	rep_1	1.5e-08
PCK2	GOBP_Triglyceride_Metabolic_Process	Human	Breast	rep_1	2.4e-04
PCK2	GOBP_Positive_Regulation_Of_Peptide_Secretion	Human	Breast	rep_2	7.3e-11
PCK2	GOBP_Alditol_Biosynthetic_Process	Human	Breast	rep_5	6.1e-21
PCK2	GOBP_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	3.5e-10
PCK2	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	9.4e-08
PCK2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Breast	rep_5	2.6e-07
PCK2	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Breast	rep_5	9.6e-12
PCK2	GOBP_Cellular_Response_To_Insulin_Stimulus	Human	Breast	rep_5	2.2e-04
PCK2	GOBP_Cellular_Response_To_Lipid	Human	Breast	rep_5	3.3e-11
PCK2	GOBP_Cellular_Response_To_Nitrogen_Compound	Human	Breast	rep_5	4.4e-13
PCK2	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	5.1e-18
PCK2	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
PCK2	GOBP_Cellular_Response_To_Peptide_Hormone_Stimulus	Human	Breast	rep_5	6.3e-04
PCK2	GOBP_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	1.2e-06
PCK2	GOBP_Glucose_Metabolic_Process	Human	Breast	rep_5	1.3e-09
PCK2	GOBP_Lipid_Biosynthetic_Process	Human	Breast	rep_5	7.0e-04
PCK2	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
PCK2	GOBP_Monosaccharide_Metabolic_Process	Human	Breast	rep_5	2.9e-08
PCK2	GOBP_Neutral_Lipid_Biosynthetic_Process	Human	Breast	rep_5	1.7e-05
PCK2	GOBP_Polyol_Biosynthetic_Process	Human	Breast	rep_5	2.7e-07
PCK2	GOBP_Positive_Regulation_Of_Establishment_Of_Protein_Localization	Human	Breast	rep_5	7.1e-09
PCK2	GOBP_Positive_Regulation_Of_Ion_Transport	Human	Breast	rep_5	2.0e-19
PCK2	GOBP_Positive_Regulation_Of_Secretion	Human	Breast	rep_5	3.3e-14
PCK2	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
PCK2	GOBP_Regulation_Of_Anion_Transport	Human	Breast	rep_5	1.6e-05
PCK2	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
PCK2	GOBP_Response_To_Extracellular_Stimulus	Human	Breast	rep_5	2.9e-12
PCK2	GOBP_Response_To_Hormone	Human	Breast	rep_5	2.9e-13
PCK2	GOBP_Response_To_Ketone	Human	Breast	rep_5	3.5e-14
PCK2	GOBP_Response_To_Lipid	Human	Breast	rep_5	1.6e-10
PCK2	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
PCK2	GOBP_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	7.5e-14
PCK2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
PCK2	GOBP_Response_To_Peptide	Human	Breast	rep_5	1.2e-15
PCK2	GOBP_Response_To_Starvation	Human	Breast	rep_5	6.9e-08
PCK2	GOBP_Response_To_Steroid_Hormone	Human	Breast	rep_5	4.5e-13
PCK2	GOBP_Signal_Release	Human	Breast	rep_5	1.1e-10
PCK2	GOBP_Alcohol_Biosynthetic_Process	Human	Breast	rep_6	9.0e-04
PCK2	GOBP_Alcohol_Metabolic_Process	Human	Breast	rep_6	1.3e-04
PCK2	GOBP_Alditol_Metabolic_Process	Human	Breast	rep_6	1.7e-09
PCK2	GOBP_Carbohydrate_Biosynthetic_Process	Human	Breast	rep_6	2.3e-09
PCK2	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
PCK2	GOBP_Cellular_Carbohydrate_Biosynthetic_Process	Human	Breast	rep_6	2.1e-04
PCK2	GOBP_Cellular_Lipid_Catabolic_Process	Human	Breast	rep_6	3.6e-11
PCK2	GOBP_Cellular_Response_To_Peptide	Human	Breast	rep_6	8.4e-11
PCK2	GOBP_Fatty_Acid_Catabolic_Process	Human	Breast	rep_6	8.9e-13
PCK2	GOBP_Glycerolipid_Metabolic_Process	Human	Breast	rep_6	9.2e-09
PCK2	GOBP_Hepaticobiliary_System_Development	Human	Breast	rep_6	1.5e-07
PCK2	GOBP_Lipid_Catabolic_Process	Human	Breast	rep_6	2.9e-05
PCK2	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
PCK2	GOBP_Monosaccharide_Biosynthetic_Process	Human	Breast	rep_6	1.7e-09
PCK2	GOBP_Nad_Metabolic_Process	Human	Breast	rep_6	1.6e-14
PCK2	GOBP_Nadh_Metabolic_Process	Human	Breast	rep_6	3.2e-09
PCK2	GOBP_Organic_Acid_Catabolic_Process	Human	Breast	rep_6	1.5e-11
PCK2	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
PCK2	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Breast	rep_6	2.5e-06
PCK2	GOBP_Oxaloacetate_Metabolic_Process	Human	Breast	rep_6	2.3e-07
PCK2	GOBP_Polyol_Metabolic_Process	Human	Breast	rep_6	2.9e-05
PCK2	GOBP_Positive_Regulation_Of_Anion_Transport	Human	Breast	rep_6	4.1e-08
PCK2	GOBP_Pyruvate_Metabolic_Process	Human	Breast	rep_6	1.0e-04
PCK2	GOBP_Short_Chain_Fatty_Acid_Catabolic_Process	Human	Breast	rep_6	1.2e-06
PCK2	GOBP_Short_Chain_Fatty_Acid_Metabolic_Process	Human	Breast	rep_6	9.6e-05
PCK2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
PCK2	GOBP_Small_Molecule_Catabolic_Process	Human	Breast	rep_6	4.7e-07
PCK2	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
PCK2	GOBP_Triglyceride_Biosynthetic_Process	Human	Skin	P5_rep1	1.7e-08
PCK2	GOBP_Epithelium_Development	Human	Skin	P9_rep3	4.2e-08
PCK2	GOBP_Nad_Metabolic_Process	Human	Skin	P10_rep1	4.9e-08
PCK2	GOBP_Alditol_Metabolic_Process	Human	Skin	P10_rep2	1.3e-15
PCK2	GOBP_Nadh_Metabolic_Process	Human	Skin	P10_rep2	1.6e-08
PCK2	GOBP_Positive_Regulation_Of_Hormone_Secretion	Human	Skin	P10_rep2	2.9e-08
PCK2	GOBP_Positive_Regulation_Of_Insulin_Secretion	Human	Skin	P10_rep2	1.5e-08
PCK2	GOBP_Positive_Regulation_Of_Ion_Transport	Human	Skin	P10_rep3	8.9e-08
PCK2	GOBP_Cellular_Response_To_Corticosteroid_Stimulus	Human	Lung	rep_1	8.4e-08
PCK2	GOBP_Cellular_Response_To_Lipid	Human	Lung	rep_1	1.3e-10
PCK2	GOBP_Response_To_Bacterium	Human	Lung	rep_1	1.1e-09
PCK2	GOBP_Response_To_Lipid	Human	Lung	rep_1	1.8e-09
PCK2	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Human	Lung	rep_1	1.7e-07
PCK2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08
PCK2	GOBP_Cellular_Homeostasis	Human	Lung	rep_2	7.3e-07
PCK2	GOBP_Lipid_Catabolic_Process	Human	Lung	rep_2	1.4e-09
PCK2	GOBP_Neutral_Lipid_Metabolic_Process	Human	Lung	rep_2	2.7e-09
PCK2	GOBP_Positive_Regulation_Of_Establishment_Of_Protein_Localization	Human	Lung	rep_2	3.5e-07
PCK2	GOBP_Regulation_Of_Hormone_Levels	Human	Lung	rep_2	1.6e-07
PCK2	GOBP_Regulation_Of_Peptide_Transport	Human	Lung	rep_2	2.6e-07
PCK2	GOBP_Regulation_Of_Secretion	Human	Lung	rep_2	9.3e-09

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PCK2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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PCK2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for PCK2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for PCK2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for PCK2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source