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Spatial pattern gene: PCDH1 (spascer ID:5097) |
Gene summary for PCDH1 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | PCDH1 | Gene ID | 5097 |
| Gene name | protocadherin 1 |
| Synonyms | PC42|PCDH42 |
| Cytomap | 5q31.3 |
| Type of gene | protein-coding |
| Description | protocadherin-1cadherin-like 1cadherin-like protein 1protocadherin 42 |
| Modification date | 20220513 |
| UniProtAcc | Q08174 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| PCDH1 | GO:0005887 | integral component of plasma membrane | 21873635 | Component |
| PCDH1 | GO:0007155 | cell adhesion | 21873635 | Process |
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Spatial pattern events for PCDH1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| PCDH1 | Human | Intestine | rep_colon1 | 34417225 | 3.04e-09 |
| PCDH1 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| PCDH1 | Human | Intestine | rep_colon4 | 34417225 | 5.53e-11 |
| PCDH1 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| PCDH1 | Human | Liver | rep_liver2 | 34417225 | 2.46e-12 |
| PCDH1 | Human | Pancreas | PDAC-A-st1 | 31932730 | 1.11e-14 |
| PCDH1 | Human | Uterus | rep_2 | 34857954 | 1.28e-06 |
| PCDH1 | Human | Breast | 1160920F | 34493872 | 2.86e-11 |
| PCDH1 | Human | Breast | CID4535 | 34493872 | 6.37e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_2_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4535_H&E  |  |
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Spatial pattern pathway has PCDH1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| PCDH1 | GOBP_Biological_Adhesion | Human | Intestine | A3 | 6.7e-11 |
| PCDH1 | GOBP_Cell_Cell_Adhesion | Human | Intestine | A3 | 2.5e-07 |
| PCDH1 | GOBP_Cell_Cell_Signaling | Human | Intestine | A3 | 6.4e-08 |
| PCDH1 | GOBP_Cell_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules | Human | Intestine | A8 | 1.2e-11 |
| PCDH1 | GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules | Human | Intestine | A8 | 1.2e-14 |
| PCDH1 | GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules | Human | Uterus | rep_1 | 2.1e-06 |
| PCDH1 | GOBP_Biological_Adhesion | Human | Uterus | rep_29 | 3.3e-06 |
| PCDH1 | GOBP_Biological_Adhesion | Human | Breast | rep_1 | 4.0e-110 |
| PCDH1 | GOBP_Cell_Cell_Adhesion | Human | Breast | rep_1 | 3.6e-45 |
| PCDH1 | GOBP_Cell_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules | Human | Breast | rep_1 | 3.2e-141 |
| PCDH1 | GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules | Human | Breast | rep_1 | 1.2e-106 |
| PCDH1 | GOBP_Cell_Cell_Signaling | Human | Breast | rep_6 | 5.0e-05 |
| PCDH1 | GOBP_Biological_Adhesion | Human | Lung | rep_2 | 6.6e-07 |
| PCDH1 | GOBP_Cell_Cell_Adhesion | Human | Lung | rep_2 | 5.3e-07 |
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PCDH1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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PCDH1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for PCDH1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for PCDH1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PCDH1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
