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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: PBX1 (spascer ID:5087)

Gene summary for PBX1

Gene summary

Gene information
	Species	Human
	Gene symbol	PBX1
	Gene ID	5087
	Gene name	PBX homeobox 1
	Synonyms	CAKUHED
	Cytomap	1q23.3
	Type of gene	protein-coding
	Description	pre-B-cell leukemia transcription factor 1homeobox protein PBX1homeobox protein PRLpre-B-cell leukemia homeobox 1
	Modification date	20220513
	UniProtAcc	P40424

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
PBX1	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	21873635	Function
PBX1	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	21873635	Function
PBX1	GO:0001654	eye development	21873635	Process
PBX1	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process
PBX1	GO:0007420	brain development	21873635	Process
PBX1	GO:0009887	animal organ morphogenesis	21873635	Process
PBX1	GO:0048568	embryonic organ development	21873635	Process
PBX1	GO:0048666	neuron development	21873635	Process

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Spatial pattern events for PBX1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
PBX1	Human	Brain	rep_1	33558695	9.49e-07
PBX1	Human	Brain	rep_2	33558695	2.57e-09
PBX1	Human	Brain	rep_4	33558695	2.10e-07
PBX1	Human	Brain	rep_7	33558695	7.50e-07
PBX1	Human	Brain	rep_9	33558695	6.71e-09
PBX1	Human	Brain	rep_10	33558695	3.23e-15
PBX1	Human	Brain	rep_11	33558695	6.86e-13
PBX1	Human	Bladder	rep_1	34385456	4.79e-08
PBX1	Human	Intestine	rep_colon2	34417225	8.12e-16
PBX1	Human	Intestine	rep_colon3	34417225	1.01e-15
PBX1	Human	Liver	rep_liver2	34417225	6.98e-16
PBX1	Human	Intestine	A4	33406409	7.35e-15
PBX1	Human	Intestine	A6	33406409	2.00e-06
PBX1	Human	Uterus	rep_1	34857954	5.13e-15
PBX1	Human	Uterus	rep_2	34857954	2.55e-15
PBX1	Human	Uterus	rep_3	34857954	1.66e-15
PBX1	Human	Uterus	rep_4	34857954	1.82e-15
PBX1	Human	Breast	1142243F	34493872	2.30e-15
PBX1	Human	Breast	1160920F	34493872	3.29e-08
PBX1	Human	Breast	CID4290	34493872	4.68e-15
PBX1	Human	Breast	CID4465	34493872	6.01e-09
PBX1	Human	Breast	CID44971	34493872	1.47e-07
PBX1	Human	Breast	CID4535	34493872	6.37e-15
PBX1	Human	Skin	P2_rep3	32946785	4.92e-07
PBX1	Human	Lung	rep_1	35355018	1.04e-12

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_4_H&E
Brain_rep_7_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Bladder_rep_1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver2_H&E
Intestine_A4_H&E
Intestine_A6_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Skin_P2_rep3_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has PBX1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
PBX1	GOBP_Central_Nervous_System_Development	Human	Brain	rep_1	2.8e-23
PBX1	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
PBX1	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
PBX1	GOBP_Neuron_Development	Human	Brain	rep_1	7.4e-34
PBX1	GOBP_Neuron_Differentiation	Human	Brain	rep_1	7.4e-34
PBX1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Brain	rep_1	1.3e-60
PBX1	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
PBX1	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
PBX1	GOBP_Nephron_Development	Human	Brain	st	2.2e-07
PBX1	GOBP_Renal_Tubule_Development	Human	Brain	st	2.9e-07
PBX1	GOBP_Appendage_Morphogenesis	Human	Bladder	rep_2	2.1e-04
PBX1	GOBP_Nephron_Development	Human	Bladder	rep_2	5.1e-04
PBX1	GOBP_Ossification	Human	Bladder	rep_2	1.1e-10
PBX1	GOBP_Positive_Regulation_Of_Transcription_Of_Notch_Receptor_Target	Human	Bladder	rep_2	3.7e-08
PBX1	GOBP_Skeletal_System_Development	Human	Bladder	rep_2	2.5e-15
PBX1	GOBP_Central_Nervous_System_Development	Human	Liver	rep_1	1.0e-70
PBX1	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
PBX1	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
PBX1	GOBP_Neuron_Development	Human	Liver	rep_1	1.5e-73
PBX1	GOBP_Neuron_Differentiation	Human	Liver	rep_1	1.5e-73
PBX1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Liver	rep_1	2.0e-49
PBX1	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
PBX1	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
PBX1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	rep_colon2	2.9e-50
PBX1	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
PBX1	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
PBX1	GOBP_Adrenal_Gland_Development	Human	Intestine	A3	1.1e-08
PBX1	GOBP_Anterior_Posterior_Pattern_Specification	Human	Intestine	A3	4.1e-08
PBX1	GOBP_Branching_Morphogenesis_Of_An_Epithelial_Tube	Human	Intestine	A3	3.4e-13
PBX1	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
PBX1	GOBP_Cell_Cycle_Phase_Transition	Human	Intestine	A3	3.5e-07
PBX1	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
PBX1	GOBP_Central_Nervous_System_Development	Human	Intestine	A3	7.1e-11
PBX1	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Intestine	A3	2.7e-15
PBX1	GOBP_Embryo_Development	Human	Intestine	A3	2.4e-07
PBX1	GOBP_Embryonic_Hemopoiesis	Human	Intestine	A3	7.3e-08
PBX1	GOBP_Embryonic_Morphogenesis	Human	Intestine	A3	1.3e-11
PBX1	GOBP_Embryonic_Organ_Development	Human	Intestine	A3	1.4e-10
PBX1	GOBP_Endocrine_System_Development	Human	Intestine	A3	8.9e-09
PBX1	GOBP_Epithelial_Tube_Morphogenesis	Human	Intestine	A3	5.0e-10
PBX1	GOBP_Gland_Development	Human	Intestine	A3	2.3e-14
PBX1	GOBP_Head_Development	Human	Intestine	A3	3.8e-09
PBX1	GOBP_Immune_System_Development	Human	Intestine	A3	4.3e-10
PBX1	GOBP_Kidney_Epithelium_Development	Human	Intestine	A3	2.0e-10
PBX1	GOBP_Lipid_Biosynthetic_Process	Human	Intestine	A3	5.0e-07
PBX1	GOBP_Mesonephros_Development	Human	Intestine	A3	1.3e-07
PBX1	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
PBX1	GOBP_Morphogenesis_Of_A_Branching_Structure	Human	Intestine	A3	2.3e-11
PBX1	GOBP_Morphogenesis_Of_An_Epithelium	Human	Intestine	A3	1.5e-09
PBX1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.3e-14
PBX1	GOBP_Negative_Regulation_Of_Developmental_Process	Human	Intestine	A3	2.6e-09
PBX1	GOBP_Nephron_Epithelium_Development	Human	Intestine	A3	3.0e-07
PBX1	GOBP_Nephron_Morphogenesis	Human	Intestine	A3	1.1e-12
PBX1	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
PBX1	GOBP_Neuron_Development	Human	Intestine	A3	1.3e-12
PBX1	GOBP_Neuron_Differentiation	Human	Intestine	A3	1.4e-11
PBX1	GOBP_Pattern_Specification_Process	Human	Intestine	A3	4.9e-07
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Intestine	A3	3.2e-16
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Human	Intestine	A3	4.1e-09
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	1.3e-18
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	2.3e-19
PBX1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	3.5e-07
PBX1	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	2.6e-15
PBX1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
PBX1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
PBX1	GOBP_Regionalization	Human	Intestine	A3	1.1e-10
PBX1	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
PBX1	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	2.6e-08
PBX1	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
PBX1	GOBP_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.7e-10
PBX1	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
PBX1	GOBP_Renal_Tubule_Development	Human	Intestine	A3	2.4e-10
PBX1	GOBP_Reproduction	Human	Intestine	A3	4.6e-19
PBX1	GOBP_Sensory_Organ_Development	Human	Intestine	A3	1.3e-12
PBX1	GOBP_Sensory_System_Development	Human	Intestine	A3	8.7e-09
PBX1	GOBP_Sex_Differentiation	Human	Intestine	A3	6.1e-18
PBX1	GOBP_Thymus_Development	Human	Intestine	A3	1.7e-10
PBX1	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
PBX1	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
PBX1	GOBP_Urogenital_System_Development	Human	Intestine	A3	2.6e-07
PBX1	GOBP_Cell_Cycle_G2_M_Phase_Transition	Human	Intestine	A8	4.0e-09
PBX1	GOBP_Embryonic_Skeletal_System_Development	Human	Intestine	A8	1.1e-07
PBX1	GOBP_Kidney_Morphogenesis	Human	Intestine	A8	9.1e-08
PBX1	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
PBX1	GOBP_Notch_Signaling_Pathway	Human	Intestine	A8	5.3e-07
PBX1	GOBP_Ossification	Human	Intestine	A8	3.0e-07
PBX1	GOBP_Positive_Regulation_Of_Transcription_Of_Notch_Receptor_Target	Human	Intestine	A8	1.2e-09
PBX1	GOBP_Spleen_Development	Human	Intestine	A8	5.9e-21
PBX1	GOBP_Steroid_Biosynthetic_Process	Human	Intestine	A8	7.2e-18
PBX1	GOBP_Steroid_Metabolic_Process	Human	Intestine	A8	7.9e-16
PBX1	GOBP_Head_Development	Human	Pancreas	PDAC-B-st1	2.0e-05
PBX1	GOBP_Maintenance_Of_Cell_Number	Human	Pancreas	PDAC-B-st1	3.7e-06
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Pancreas	PDAC-B-st1	4.0e-05
PBX1	GOBP_Nephron_Development	Human	Pancreas	PDAC-A-st2	2.6e-05
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Human	Pancreas	PDAC-A-st2	8.7e-06
PBX1	GOBP_Thymus_Development	Human	Pancreas	PDAC-A-st2	2.9e-07
PBX1	GOBP_Mesonephric_Tubule_Morphogenesis	Human	Pancreas	PDAC-A-st3	8.2e-05
PBX1	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Uterus	rep_1	1.6e-06
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_1	6.5e-06
PBX1	GOBP_Somatic_Stem_Cell_Population_Maintenance	Human	Uterus	rep_25	7.4e-09
PBX1	GOBP_Adrenal_Gland_Development	Human	Uterus	rep_26	2.6e-07
PBX1	GOBP_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	1.9e-06
PBX1	GOBP_Gland_Development	Human	Uterus	rep_26	1.6e-07
PBX1	GOBP_Immune_System_Development	Human	Uterus	rep_26	1.0e-06
PBX1	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Human	Uterus	rep_26	2.5e-07
PBX1	GOBP_Pattern_Specification_Process	Human	Uterus	rep_26	3.6e-06
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	2.1e-09
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Uterus	rep_26	1.2e-15
PBX1	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.1e-08
PBX1	GOBP_Regionalization	Human	Uterus	rep_26	2.0e-06
PBX1	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	9.3e-07
PBX1	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
PBX1	GOBP_Steroid_Biosynthetic_Process	Human	Uterus	rep_26	4.3e-06
PBX1	GOBP_Steroid_Metabolic_Process	Human	Uterus	rep_26	1.0e-07
PBX1	GOBP_Thymus_Development	Human	Uterus	rep_26	1.4e-07
PBX1	GOBP_Proximal_Distal_Pattern_Formation	Human	Uterus	rep_29	6.2e-06
PBX1	GOBP_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_29	2.8e-06
PBX1	GOBP_Regulation_Of_Neuron_Differentiation	Human	Uterus	rep_29	6.5e-07
PBX1	GOBP_Adrenal_Gland_Development	Human	Breast	rep_1	4.8e-99
PBX1	GOBP_Animal_Organ_Morphogenesis	Human	Breast	rep_1	5.4e-25
PBX1	GOBP_Branching_Morphogenesis_Of_An_Epithelial_Tube	Human	Breast	rep_1	1.9e-33
PBX1	GOBP_Central_Nervous_System_Development	Human	Breast	rep_1	5.1e-04
PBX1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Human	Breast	rep_1	7.7e-07
PBX1	GOBP_Endocrine_System_Development	Human	Breast	rep_1	9.5e-128
PBX1	GOBP_Epithelium_Development	Human	Breast	rep_1	2.0e-22
PBX1	GOBP_Gland_Development	Human	Breast	rep_1	2.0e-26
PBX1	GOBP_Head_Development	Human	Breast	rep_1	1.0e-09
PBX1	GOBP_Immune_System_Development	Human	Breast	rep_1	1.0e-31
PBX1	GOBP_Kidney_Epithelium_Development	Human	Breast	rep_1	1.2e-45
PBX1	GOBP_Mesonephric_Tubule_Morphogenesis	Human	Breast	rep_1	9.8e-17
PBX1	GOBP_Mesonephros_Development	Human	Breast	rep_1	2.5e-26
PBX1	GOBP_Morphogenesis_Of_An_Epithelium	Human	Breast	rep_1	2.3e-18
PBX1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	1.0e-15
PBX1	GOBP_Negative_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.5e-04
PBX1	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Human	Breast	rep_1	3.9e-19
PBX1	GOBP_Nephron_Development	Human	Breast	rep_1	1.9e-91
PBX1	GOBP_Nephron_Epithelium_Development	Human	Breast	rep_1	1.0e-58
PBX1	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
PBX1	GOBP_Neuron_Development	Human	Breast	rep_1	2.5e-26
PBX1	GOBP_Neuron_Differentiation	Human	Breast	rep_1	1.1e-16
PBX1	GOBP_Notch_Signaling_Pathway	Human	Breast	rep_1	2.7e-27
PBX1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	9.2e-11
PBX1	GOBP_Positive_Regulation_Of_Transcription_Of_Notch_Receptor_Target	Human	Breast	rep_1	1.3e-11
PBX1	GOBP_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	2.5e-42
PBX1	GOBP_Regulation_Of_Neuron_Differentiation	Human	Breast	rep_1	4.2e-29
PBX1	GOBP_Renal_Tubule_Development	Human	Breast	rep_1	2.7e-79
PBX1	GOBP_Tissue_Morphogenesis	Human	Breast	rep_1	1.4e-30
PBX1	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
PBX1	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
PBX1	GOBP_Urogenital_System_Development	Human	Breast	rep_1	1.4e-52
PBX1	GOBP_Anterior_Posterior_Pattern_Specification	Human	Breast	rep_5	1.5e-08
PBX1	GOBP_Appendage_Development	Human	Breast	rep_5	1.7e-08
PBX1	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Breast	rep_5	1.5e-12
PBX1	GOBP_Embryo_Development	Human	Breast	rep_5	5.5e-08
PBX1	GOBP_Embryonic_Hemopoiesis	Human	Breast	rep_5	1.6e-05
PBX1	GOBP_Embryonic_Morphogenesis	Human	Breast	rep_5	2.0e-06
PBX1	GOBP_Embryonic_Organ_Development	Human	Breast	rep_5	3.3e-05
PBX1	GOBP_Lipid_Biosynthetic_Process	Human	Breast	rep_5	7.0e-04
PBX1	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
PBX1	GOBP_Morphogenesis_Of_A_Branching_Structure	Human	Breast	rep_5	5.4e-11
PBX1	GOBP_Pattern_Specification_Process	Human	Breast	rep_5	3.7e-14
PBX1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
PBX1	GOBP_Proximal_Distal_Pattern_Formation	Human	Breast	rep_5	1.1e-04
PBX1	GOBP_Regionalization	Human	Breast	rep_5	5.8e-16
PBX1	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
PBX1	GOBP_Reproduction	Human	Breast	rep_5	8.1e-06
PBX1	GOBP_Spleen_Development	Human	Breast	rep_5	7.1e-08
PBX1	GOBP_Appendage_Morphogenesis	Human	Breast	rep_6	4.4e-06
PBX1	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
PBX1	GOBP_Cell_Cycle_G2_M_Phase_Transition	Human	Breast	rep_6	3.0e-12
PBX1	GOBP_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	4.9e-09
PBX1	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
PBX1	GOBP_Embryonic_Appendage_Morphogenesis	Human	Breast	rep_6	7.6e-10
PBX1	GOBP_Kidney_Morphogenesis	Human	Breast	rep_6	2.4e-05
PBX1	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
PBX1	GOBP_Nephron_Morphogenesis	Human	Breast	rep_6	1.5e-05
PBX1	GOBP_Ossification	Human	Breast	rep_6	8.4e-04
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	7.0e-10
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Human	Breast	rep_6	3.5e-09
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	1.4e-09
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	7.5e-09
PBX1	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	2.5e-13
PBX1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
PBX1	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Human	Breast	rep_6	7.4e-13
PBX1	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	2.7e-07
PBX1	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
PBX1	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
PBX1	GOBP_Sensory_Organ_Development	Human	Breast	rep_6	1.3e-09
PBX1	GOBP_Sensory_System_Development	Human	Breast	rep_6	8.2e-06
PBX1	GOBP_Sex_Differentiation	Human	Breast	rep_6	4.2e-05
PBX1	GOBP_Steroid_Biosynthetic_Process	Human	Breast	rep_6	2.7e-04
PBX1	GOBP_Steroid_Metabolic_Process	Human	Breast	rep_6	6.6e-05
PBX1	GOBP_Thymus_Development	Human	Breast	rep_6	9.4e-06
PBX1	GOBP_Tissue_Morphogenesis	Human	Skin	P2_rep1	2.9e-08
PBX1	GOBP_Endocrine_System_Development	Human	Skin	P5_rep1	7.6e-14
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Skin	P5_rep1	7.8e-10
PBX1	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Skin	P5_rep1	4.9e-14
PBX1	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Skin	P5_rep1	8.2e-10
PBX1	GOBP_Proximal_Distal_Pattern_Formation	Human	Skin	P5_rep1	7.1e-08
PBX1	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Human	Skin	P5_rep1	2.0e-09
PBX1	GOBP_Urogenital_System_Development	Human	Skin	P5_rep1	2.2e-12
PBX1	GOBP_Epithelium_Development	Human	Skin	P9_rep3	4.2e-08
PBX1	GOBP_Somatic_Stem_Cell_Population_Maintenance	Human	Skin	P10_rep1	6.2e-14
PBX1	GOBP_Spleen_Development	Human	Skin	P10_rep1	5.0e-14
PBX1	GOBP_Embryonic_Hemopoiesis	Human	Skin	P10_rep2	8.6e-27
PBX1	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Human	Skin	P10_rep2	4.1e-22
PBX1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Human	Lung	rep_1	5.3e-09
PBX1	GOBP_Negative_Regulation_Of_Developmental_Process	Human	Lung	rep_1	9.2e-08
PBX1	GOBP_Ossification	Human	Lung	rep_1	8.0e-09
PBX1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Lung	rep_1	7.3e-07
PBX1	GOBP_Immune_System_Development	Human	Lung	rep_2	7.9e-07

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PBX1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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PBX1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for PBX1 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
PBX1	Uterus	early	Glandular	FAM76B,MINK1,LDLRAD4, etc.	0.289
PBX1	Uterus	early	Glandular_secretory	FAM76B,MINK1,LDLRAD4, etc.	0.263
PBX1	Uterus	early	SOX9_LGR5	FAM76B,MINK1,LDLRAD4, etc.	0.365
PBX1	Uterus	early	SOX9	FAM76B,MINK1,LDLRAD4, etc.	0.362
PBX1	Uterus	mid	Glandular_secretory	PGR,ZNF563,ACSF2, etc.	0.274
PBX1	Uterus	late	Glandular_secretory	MBP,PRICKLE2,CXXC4, etc.	0.313
PBX1	Uterus	late	Ciliated	MBP,PRICKLE2,CXXC4, etc.	0.343
PBX1	Intestine	development	Fibroblasts	C1QTNF3,MEIS2,DCN, etc.	0.574
PBX1	Intestine	development	MyoFibroblasts	C1QTNF3,MEIS2,DCN, etc.	0.298
Pbx1	Lymph	control	Mature B	Rab7b,Fosb,Ece1, etc.	0.268
Pbx1	Lymph	control	Migratory DCs	Rab7b,Fosb,Ece1, etc.	0.28
PBX1	Skin	tumor	Keratinocyte	FBLN1,LMCD1,SDK1, etc.	0.255
PBX1	Skin	tumor	Fibroblast	FBLN1,LMCD1,SDK1, etc.	0.32
PBX1	Uterus	proliferative	SOX9	THSD4,LPAR3,AHNAK, etc.	0.528
PBX1	Uterus	proliferative	Ciliated	THSD4,LPAR3,AHNAK, etc.	0.254
PBX1	Uterus	proliferative	SOX9_LGR5	THSD4,LPAR3,AHNAK, etc.	0.359
PBX1	Uterus	proliferative	SOX9_prolif	THSD4,LPAR3,AHNAK, etc.	0.328

Motif information.

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Related Drugs for PBX1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for PBX1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
PBX1	C0006413	Burkitt Lymphoma	2	CTD_human;ORPHANET
PBX1	C0343640	African Burkitt's lymphoma	2	CTD_human
PBX1	C1968949	Cakut	2	GENOMICS_ENGLAND
PBX1	C4721444	Burkitt Leukemia	2	CTD_human
PBX1	C0013146	Drug abuse	1	CTD_human
PBX1	C0013170	Drug habituation	1	CTD_human
PBX1	C0013222	Drug Use Disorders	1	CTD_human
PBX1	C0029231	Organic Mental Disorders, Substance-Induced	1	CTD_human
PBX1	C0038580	Substance Dependence	1	CTD_human
PBX1	C0038586	Substance Use Disorders	1	CTD_human
PBX1	C0236969	Substance-Related Disorders	1	CTD_human
PBX1	C0431692	Bilateral renal hypoplasia	1	ORPHANET
PBX1	C0740858	Substance abuse problem	1	CTD_human
PBX1	C1510472	Drug Dependence	1	CTD_human
PBX1	C4316881	Prescription Drug Abuse	1	CTD_human
PBX1	C4539968	CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT SYNDROME WITH OR WITHOUT HEARING LOSS, ABNORMAL EARS, OR DEVELOPMENTAL DELAY	1	GENOMICS_ENGLAND