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Spatial pattern gene: PAFAH1B3 (spascer ID:5050) |
Gene summary for PAFAH1B3 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | PAFAH1B3 | Gene ID | 5050 |
| Gene name | platelet activating factor acetylhydrolase 1b catalytic subunit 3 |
| Synonyms | PAFAHG |
| Cytomap | 19q13.2 |
| Type of gene | protein-coding |
| Description | platelet-activating factor acetylhydrolase IB subunit alpha1PAF acetylhydrolase 29 kDa subunitPAF-AH 29 kDa subunitPAF-AH subunit gammaPAF-AH1b alpha 1 subunitPAFAH subunit gammaepididymis secretory sperm binding proteinplatelet-activating factor a |
| Modification date | 20220513 |
| UniProtAcc | Q15102 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| PAFAH1B3 | GO:0005737 | cytoplasm | 21873635 | Component |
| PAFAH1B3 | GO:0007420 | brain development | 21873635 | Process |
| PAFAH1B3 | GO:0047179 | platelet-activating factor acetyltransferase activity | 21873635 | Function |
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Spatial pattern events for PAFAH1B3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| PAFAH1B3 | Human | Intestine | rep_colon1 | 34417225 | 3.42e-15 |
| PAFAH1B3 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| PAFAH1B3 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| PAFAH1B3 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| PAFAH1B3 | Human | Intestine | A1 | 33406409 | 9.39e-11 |
| PAFAH1B3 | Human | Intestine | A2 | 33406409 | 2.47e-15 |
| PAFAH1B3 | Human | Intestine | A4 | 33406409 | 5.51e-06 |
| PAFAH1B3 | Human | Uterus | rep_3 | 34857954 | 1.78e-09 |
| PAFAH1B3 | Human | Breast | 1142243F | 34493872 | 1.27e-10 |
| PAFAH1B3 | Human | Breast | 1160920F | 34493872 | 2.14e-08 |
| PAFAH1B3 | Human | Breast | CID4465 | 34493872 | 5.09e-10 |
| PAFAH1B3 | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Intestine_A1_H&E  |  |
Intestine_A2_H&E  |  |
Intestine_A4_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4465_H&E  |  |
Breast_CID44971_H&E  |  |
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Spatial pattern pathway has PAFAH1B3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| PAFAH1B3 | GOBP_Central_Nervous_System_Development | Human | Brain | rep_1 | 2.8e-23 |
| PAFAH1B3 | GOBP_Lipid_Metabolic_Process | Human | Brain | rep_1 | 2.8e-23 |
| PAFAH1B3 | GOBP_Central_Nervous_System_Development | Human | Liver | rep_1 | 1.0e-70 |
| PAFAH1B3 | GOBP_Lipid_Metabolic_Process | Human | Liver | rep_1 | 1.0e-70 |
| PAFAH1B3 | GOBP_Central_Nervous_System_Development | Human | Intestine | A3 | 7.1e-11 |
| PAFAH1B3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Intestine | A3 | 2.7e-15 |
| PAFAH1B3 | GOBP_Gamete_Generation | Human | Intestine | A3 | 4.2e-13 |
| PAFAH1B3 | GOBP_Head_Development | Human | Intestine | A3 | 3.8e-09 |
| PAFAH1B3 | GOBP_Male_Gamete_Generation | Human | Intestine | A3 | 4.8e-15 |
| PAFAH1B3 | GOBP_Multicellular_Organism_Reproduction | Human | Intestine | A3 | 4.1e-15 |
| PAFAH1B3 | GOBP_Reproduction | Human | Intestine | A3 | 4.6e-19 |
| PAFAH1B3 | GOBP_Lipid_Catabolic_Process | Human | Intestine | A8 | 3.2e-08 |
| PAFAH1B3 | GOBP_Lipid_Metabolic_Process | Human | Intestine | A8 | 1.1e-11 |
| PAFAH1B3 | GOBP_Head_Development | Human | Pancreas | PDAC-B-st1 | 2.0e-05 |
| PAFAH1B3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Uterus | rep_1 | 1.6e-06 |
| PAFAH1B3 | GOBP_Gamete_Generation | Human | Uterus | rep_26 | 3.8e-10 |
| PAFAH1B3 | GOBP_Male_Gamete_Generation | Human | Uterus | rep_26 | 7.4e-14 |
| PAFAH1B3 | GOBP_Central_Nervous_System_Development | Human | Breast | rep_1 | 5.1e-04 |
| PAFAH1B3 | GOBP_Head_Development | Human | Breast | rep_1 | 1.0e-09 |
| PAFAH1B3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Breast | rep_5 | 1.5e-12 |
| PAFAH1B3 | GOBP_Lipid_Metabolic_Process | Human | Breast | rep_5 | 2.9e-06 |
| PAFAH1B3 | GOBP_Multicellular_Organism_Reproduction | Human | Breast | rep_5 | 8.1e-07 |
| PAFAH1B3 | GOBP_Reproduction | Human | Breast | rep_5 | 8.1e-06 |
| PAFAH1B3 | GOBP_Gamete_Generation | Human | Breast | rep_6 | 7.3e-08 |
| PAFAH1B3 | GOBP_Lipid_Catabolic_Process | Human | Breast | rep_6 | 2.9e-05 |
| PAFAH1B3 | GOBP_Male_Gamete_Generation | Human | Breast | rep_6 | 4.3e-06 |
| PAFAH1B3 | GOBP_Lipid_Catabolic_Process | Human | Lung | rep_2 | 1.4e-09 |
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PAFAH1B3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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PAFAH1B3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for PAFAH1B3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for PAFAH1B3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PAFAH1B3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
