|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: PABPC3 (spascer ID:5042) |
Gene summary for PABPC3 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | PABPC3 | Gene ID | 5042 |
| Gene name | poly(A) binding protein cytoplasmic 3 |
| Synonyms | PABP3|PABPL3|tPABP |
| Cytomap | 13q12.13 |
| Type of gene | protein-coding |
| Description | polyadenylate-binding protein 3PABP-3poly(A)-binding protein 3poly(A)-binding protein-like 3testis PABPtestis-specific poly(A)-binding protein (PABP)testis-specific poly(A)-binding protein 3 |
| Modification date | 20220513 |
| UniProtAcc | Q9H361 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| PABPC3 | GO:0003723 | RNA binding | 21873635 | Function |
| PABPC3 | GO:0003730 | mRNA 3'-UTR binding | 21873635 | Function |
| PABPC3 | GO:0005634 | nucleus | 21873635 | Component |
| PABPC3 | GO:0005829 | cytosol | 21873635 | Component |
| PABPC3 | GO:0008143 | poly(A) binding | 21873635 | Function |
| PABPC3 | GO:0008266 | poly(U) RNA binding | 21873635 | Function |
| PABPC3 | GO:0010494 | cytoplasmic stress granule | 21873635 | Component |
| PABPC3 | GO:1990904 | ribonucleoprotein complex | 21873635 | Component |
Top |
Spatial pattern events for PABPC3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| PABPC3 | Human | Intestine | rep_colon1 | 34417225 | 5.81e-08 |
| PABPC3 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| PABPC3 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| PABPC3 | Human | Liver | rep_liver4 | 34417225 | 7.71e-16 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Top |
Spatial pattern pathway has PABPC3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| PABPC3 | GOBP_Mrna_Metabolic_Process | Human | Intestine | A3 | 7.7e-20 |
| PABPC3 | GOBP_Mrna_Metabolic_Process | Human | Pancreas | PDAC-B-st1 | 2.6e-05 |
| PABPC3 | GOBP_Mrna_Metabolic_Process | Human | Breast | rep_6 | 3.0e-08 |
| PABPC3 | GOBP_Mrna_Metabolic_Process | Human | Skin | P5_rep3 | 1.8e-08 |
Top |
PABPC3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
PABPC3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for PABPC3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for PABPC3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for PABPC3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
