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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: PA2G4 (spascer ID:5036)

Gene summary for PA2G4

Gene summary

Gene information
	Species	Human
	Gene symbol	PA2G4
	Gene ID	5036
	Gene name	proliferation-associated 2G4
	Synonyms	EBP1\|HG4-1\|p38-2G4
	Cytomap	12q13.2
	Type of gene	protein-coding
	Description	proliferation-associated protein 2G4ErbB-3 binding protein 1ErbB-3 receptor binding proteinErbB3-binding protein Ebp1cell cycle protein p38-2G4 homologerbB3-binding protein 1proliferation-associated 2G4, 38kDproliferation-associated 2G4, 38kDa
	Modification date	20220513
	UniProtAcc	Q9UQ80

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for PA2G4

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
PA2G4	Human	Intestine	rep_colon1	34417225	1.95e-15
PA2G4	Human	Intestine	rep_colon2	34417225	8.12e-16
PA2G4	Human	Intestine	rep_colon3	34417225	1.01e-15
PA2G4	Human	Intestine	rep_colon4	34417225	1.14e-15
PA2G4	Human	Liver	rep_liver1	34417225	1.89e-15
PA2G4	Human	Liver	rep_liver2	34417225	6.98e-16
PA2G4	Human	Liver	rep_liver4	34417225	7.71e-16
PA2G4	Human	Intestine	A1	33406409	6.31e-15
PA2G4	Human	Intestine	A2	33406409	3.85e-15
PA2G4	Human	Uterus	rep_3	34857954	1.66e-15
PA2G4	Human	Breast	A3	34650042	3.82e-06
PA2G4	Human	Breast	A5	34650042	1.87e-09
PA2G4	Human	Breast	CID44971	34493872	3.56e-07
PA2G4	Human	Skin	P2_rep2	32946785	4.27e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_3_H&E
Breast_A3_H&E
Breast_A5_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has PA2G4 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
PA2G4	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
PA2G4	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
PA2G4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	2.8e-23
PA2G4	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
PA2G4	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
PA2G4	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
PA2G4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	1.0e-70
PA2G4	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
PA2G4	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
PA2G4	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
PA2G4	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
PA2G4	GOBP_Amide_Biosynthetic_Process	Human	Intestine	A1	6.4e-07
PA2G4	GOBP_Peptide_Biosynthetic_Process	Human	Intestine	A1	4.6e-10
PA2G4	GOBP_Ribosome_Biogenesis	Human	Intestine	A1	6.5e-08
PA2G4	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
PA2G4	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Intestine	A3	4.0e-14
PA2G4	GOBP_Exocytosis	Human	Intestine	A3	4.7e-10
PA2G4	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
PA2G4	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
PA2G4	GOBP_Ncrna_Metabolic_Process	Human	Intestine	A3	8.6e-07
PA2G4	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Intestine	A3	5.9e-17
PA2G4	GOBP_Negative_Regulation_Of_Cell_Death	Human	Intestine	A3	5.8e-14
PA2G4	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
PA2G4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.6e-14
PA2G4	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
PA2G4	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Human	Intestine	A3	4.2e-08
PA2G4	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
PA2G4	GOBP_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.7e-10
PA2G4	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Human	Intestine	A3	2.1e-07
PA2G4	GOBP_Rna_Processing	Human	Intestine	A3	3.9e-09
PA2G4	GOBP_Secretion	Human	Intestine	A3	1.8e-13
PA2G4	GOBP_Myeloid_Leukocyte_Activation	Human	Intestine	A8	3.8e-18
PA2G4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Intestine	A8	8.5e-11
PA2G4	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Pancreas	PDAC-B-st1	1.2e-05
PA2G4	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
PA2G4	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
PA2G4	GOBP_Ncrna_Processing	Human	Uterus	rep_1	4.5e-06
PA2G4	GOBP_Ribosome_Biogenesis	Human	Uterus	rep_1	9.5e-06
PA2G4	GOBP_Rrna_Metabolic_Process	Human	Uterus	rep_1	2.4e-07
PA2G4	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Uterus	rep_26	1.5e-11
PA2G4	GOBP_Exocytosis	Human	Uterus	rep_26	5.1e-10
PA2G4	GOBP_Myeloid_Leukocyte_Activation	Human	Uterus	rep_26	1.4e-11
PA2G4	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
PA2G4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_26	1.6e-09
PA2G4	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
PA2G4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Uterus	rep_28	8.7e-06
PA2G4	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
PA2G4	GOBP_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_29	2.8e-06
PA2G4	GOBP_Exocytosis	Human	Breast	rep_1	2.8e-29
PA2G4	GOBP_Myeloid_Leukocyte_Activation	Human	Breast	rep_1	2.2e-37
PA2G4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	7.1e-96
PA2G4	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
PA2G4	GOBP_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	2.5e-42
PA2G4	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
PA2G4	GOBP_Negative_Regulation_Of_Cell_Death	Human	Breast	rep_5	1.9e-07
PA2G4	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
PA2G4	GOBP_Amide_Biosynthetic_Process	Human	Breast	rep_6	8.7e-05
PA2G4	GOBP_Cellular_Amide_Metabolic_Process	Human	Breast	rep_6	5.6e-05
PA2G4	GOBP_Ncrna_Metabolic_Process	Human	Breast	rep_6	1.9e-04
PA2G4	GOBP_Ncrna_Processing	Human	Breast	rep_6	1.3e-05
PA2G4	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Breast	rep_6	2.6e-08
PA2G4	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
PA2G4	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
PA2G4	GOBP_Peptide_Biosynthetic_Process	Human	Breast	rep_6	1.6e-05
PA2G4	GOBP_Peptide_Metabolic_Process	Human	Breast	rep_6	8.7e-05
PA2G4	GOBP_Ribonucleoprotein_Complex_Biogenesis	Human	Breast	rep_6	1.3e-07
PA2G4	GOBP_Ribosome_Biogenesis	Human	Breast	rep_6	2.0e-06
PA2G4	GOBP_Rna_Processing	Human	Breast	rep_6	3.5e-06
PA2G4	GOBP_Rrna_Metabolic_Process	Human	Breast	rep_6	4.0e-06
PA2G4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Skin	P10_rep2	1.1e-22
PA2G4	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
PA2G4	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Lung	rep_2	8.0e-10

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PA2G4 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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PA2G4 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for PA2G4 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for PA2G4

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for PA2G4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source