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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: OSBP (spascer ID:5007)

Gene summary for OSBP

Gene summary

Gene information
	Species	Human
	Gene symbol	OSBP
	Gene ID	5007
	Gene name	oxysterol binding protein
	Synonyms	OSBP1
	Cytomap	11q12.1
	Type of gene	protein-coding
	Description	oxysterol-binding protein 1
	Modification date	20220513
	UniProtAcc	P22059

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
OSBP	GO:0005829	cytosol	21873635	Component
OSBP	GO:0005886	plasma membrane	21873635	Component
OSBP	GO:0015248	sterol transporter activity	21873635	Function
OSBP	GO:0016020	membrane	21873635	Component
OSBP	GO:0032934	sterol binding	21873635	Function
OSBP	GO:0043231	intracellular membrane-bounded organelle	21873635	Component
OSBP	GO:0097038	perinuclear endoplasmic reticulum	21873635	Component

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Spatial pattern events for OSBP

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
OSBP	Human	Liver	rep_liver1	34417225	5.30e-06
OSBP	Human	Liver	rep_liver2	34417225	6.98e-16
OSBP	Human	Uterus	rep_2	34857954	1.36e-09
OSBP	Human	Uterus	rep_4	34857954	2.54e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_2_H&E
Uterus_rep_4_H&E

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Spatial pattern pathway has OSBP envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
OSBP	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
OSBP	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
OSBP	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
OSBP	GOBP_Lipid_Biosynthetic_Process	Human	Intestine	A3	5.0e-07
OSBP	GOBP_Membrane_Organization	Human	Intestine	A3	2.7e-18
OSBP	GOBP_Organic_Hydroxy_Compound_Transport	Human	Intestine	A3	7.3e-09
OSBP	GOBP_Bile_Acid_Biosynthetic_Process	Human	Intestine	A8	1.0e-12
OSBP	GOBP_Bile_Acid_Metabolic_Process	Human	Intestine	A8	5.1e-08
OSBP	GOBP_Intracellular_Lipid_Transport	Human	Intestine	A8	8.1e-07
OSBP	GOBP_Lipid_Localization	Human	Intestine	A8	2.5e-15
OSBP	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
OSBP	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
OSBP	GOBP_Organic_Acid_Biosynthetic_Process	Human	Intestine	A8	2.1e-08
OSBP	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
OSBP	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Intestine	A8	1.2e-10
OSBP	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Intestine	A8	6.4e-10
OSBP	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
OSBP	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
OSBP	GOBP_Steroid_Biosynthetic_Process	Human	Intestine	A8	7.2e-18
OSBP	GOBP_Steroid_Metabolic_Process	Human	Intestine	A8	7.9e-16
OSBP	GOBP_Intermembrane_Lipid_Transfer	Human	Uterus	rep_1	3.9e-08
OSBP	GOBP_Sterol_Transport	Human	Uterus	rep_1	2.9e-06
OSBP	GOBP_Bile_Acid_Metabolic_Process	Human	Uterus	rep_26	2.7e-09
OSBP	GOBP_Intracellular_Lipid_Transport	Human	Uterus	rep_26	1.4e-09
OSBP	GOBP_Lipid_Localization	Human	Uterus	rep_26	3.7e-10
OSBP	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	1.0e-07
OSBP	GOBP_Organic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	2.3e-06
OSBP	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
OSBP	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Uterus	rep_26	3.2e-10
OSBP	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Uterus	rep_26	2.5e-08
OSBP	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
OSBP	GOBP_Steroid_Biosynthetic_Process	Human	Uterus	rep_26	4.3e-06
OSBP	GOBP_Steroid_Metabolic_Process	Human	Uterus	rep_26	1.0e-07
OSBP	GOBP_Bile_Acid_Biosynthetic_Process	Human	Uterus	rep_29	2.7e-06
OSBP	GOBP_Organic_Hydroxy_Compound_Transport	Human	Uterus	rep_29	3.2e-06
OSBP	GOBP_Intracellular_Lipid_Transport	Human	Breast	rep_1	1.2e-92
OSBP	GOBP_Intracellular_Sterol_Transport	Human	Breast	rep_1	3.7e-83
OSBP	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Breast	rep_1	7.3e-16
OSBP	GOBP_Organic_Hydroxy_Compound_Transport	Human	Breast	rep_1	9.0e-228
OSBP	GOBP_Sterol_Transport	Human	Breast	rep_1	5.3e-15
OSBP	GOBP_Lipid_Biosynthetic_Process	Human	Breast	rep_5	7.0e-04
OSBP	GOBP_Lipid_Localization	Human	Breast	rep_5	1.4e-06
OSBP	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
OSBP	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Breast	rep_5	2.9e-17
OSBP	GOBP_Organic_Acid_Biosynthetic_Process	Human	Breast	rep_5	3.5e-09
OSBP	GOBP_Bile_Acid_Metabolic_Process	Human	Breast	rep_6	8.3e-05
OSBP	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
OSBP	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
OSBP	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
OSBP	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Human	Breast	rep_6	2.5e-06
OSBP	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
OSBP	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
OSBP	GOBP_Steroid_Biosynthetic_Process	Human	Breast	rep_6	2.7e-04
OSBP	GOBP_Steroid_Metabolic_Process	Human	Breast	rep_6	6.6e-05

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OSBP function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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OSBP function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for OSBP envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for OSBP

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for OSBP

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source