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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ORM2 (spascer ID:5005)

Gene summary for ORM2

Gene summary

Gene information
	Species	Human
	Gene symbol	ORM2
	Gene ID	5005
	Gene name	orosomucoid 2
	Synonyms	AGP-B\|AGP-B'\|AGP2
	Cytomap	9q32
	Type of gene	protein-coding
	Description	alpha-1-acid glycoprotein 2AGP 2OMD 2alpha-1-acid glycoprotein, type 2
	Modification date	20220513
	UniProtAcc	P19652

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ORM2	GO:0005615	extracellular space	21873635	Component

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Spatial pattern events for ORM2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ORM2	Human	Prostate	rep_2	29925878	2.69e-10
ORM2	Human	Liver	rep_1	34792289	2.38e-14
ORM2	Human	Liver	rep_liver1	34417225	1.89e-15
ORM2	Human	Liver	rep_liver2	34417225	1.27e-15
ORM2	Human	Liver	rep_liver3	34417225	3.51e-15
ORM2	Human	Liver	rep_liver4	34417225	7.71e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E

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Spatial pattern pathway has ORM2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ORM2	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
ORM2	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
ORM2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	2.8e-23
ORM2	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Brain	rep_1	4.4e-07
ORM2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
ORM2	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
ORM2	GOBP_Acute_Inflammatory_Response	Human	Brain	rep_4	5.6e-28
ORM2	GOBP_Acute_Phase_Response	Human	Brain	rep_4	6.7e-28
ORM2	GOBP_Cytokine_Production	Human	Brain	rep_4	4.1e-17
ORM2	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
ORM2	GOBP_Inflammatory_Response	Human	Brain	rep_4	5.6e-28
ORM2	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Brain	rep_4	4.1e-17
ORM2	GOBP_Platelet_Degranulation	Human	Brain	st	2.6e-38
ORM2	GOBP_Acute_Inflammatory_Response	Human	Liver	rep_1	1.1e-67
ORM2	GOBP_Acute_Phase_Response	Human	Liver	rep_1	2.9e-51
ORM2	GOBP_Cytokine_Production	Human	Liver	rep_1	1.0e-70
ORM2	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
ORM2	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
ORM2	GOBP_Inflammatory_Response	Human	Liver	rep_1	1.1e-67
ORM2	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
ORM2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	1.0e-70
ORM2	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Liver	rep_1	6.0e-76
ORM2	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Liver	rep_1	3.7e-85
ORM2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
ORM2	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
ORM2	GOBP_Acute_Phase_Response	Human	Intestine	rep_colon2	7.3e-11
ORM2	GOBP_Acute_Inflammatory_Response	Human	Intestine	rep_colon4	3.1e-51
ORM2	GOBP_Cytokine_Production	Human	Intestine	rep_colon4	9.0e-12
ORM2	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
ORM2	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
ORM2	GOBP_Inflammatory_Response	Human	Intestine	rep_colon4	3.1e-51
ORM2	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
ORM2	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	rep_colon4	1.9e-09
ORM2	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	rep_colon4	6.4e-48
ORM2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
ORM2	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
ORM2	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
ORM2	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Intestine	A3	4.0e-14
ORM2	GOBP_Cytokine_Production	Human	Intestine	A3	8.9e-12
ORM2	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
ORM2	GOBP_Exocytosis	Human	Intestine	A3	4.7e-10
ORM2	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
ORM2	GOBP_Inflammatory_Response	Human	Intestine	A3	2.9e-09
ORM2	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
ORM2	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	A3	8.0e-16
ORM2	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	A3	3.7e-11
ORM2	GOBP_Positive_Regulation_Of_Interleukin_1_Production	Human	Intestine	A3	1.7e-08
ORM2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
ORM2	GOBP_Positive_Regulation_Of_Tumor_Necrosis_Factor_Superfamily_Cytokine_Production	Human	Intestine	A3	4.9e-07
ORM2	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
ORM2	GOBP_Secretion	Human	Intestine	A3	1.8e-13
ORM2	GOBP_Acute_Inflammatory_Response	Human	Intestine	A8	5.9e-12
ORM2	GOBP_Acute_Phase_Response	Human	Intestine	A8	3.3e-07
ORM2	GOBP_Interleukin_1_Production	Human	Intestine	A8	4.5e-17
ORM2	GOBP_Myeloid_Leukocyte_Activation	Human	Intestine	A8	3.8e-18
ORM2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Intestine	A8	8.5e-11
ORM2	GOBP_Platelet_Degranulation	Human	Intestine	A8	7.1e-10
ORM2	GOBP_Tumor_Necrosis_Factor_Superfamily_Cytokine_Production	Human	Intestine	A8	6.2e-10
ORM2	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Pancreas	PDAC-B-st1	1.2e-05
ORM2	GOBP_Acute_Phase_Response	Human	Uterus	rep_2	1.2e-09
ORM2	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
ORM2	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
ORM2	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
ORM2	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
ORM2	GOBP_Platelet_Degranulation	Human	Uterus	rep_25	3.9e-10
ORM2	GOBP_Positive_Regulation_Of_Interleukin_1_Production	Human	Uterus	rep_25	7.3e-15
ORM2	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Uterus	rep_26	1.5e-11
ORM2	GOBP_Exocytosis	Human	Uterus	rep_26	5.1e-10
ORM2	GOBP_Interleukin_1_Production	Human	Uterus	rep_26	4.3e-08
ORM2	GOBP_Myeloid_Leukocyte_Activation	Human	Uterus	rep_26	1.4e-11
ORM2	GOBP_Acute_Inflammatory_Response	Human	Uterus	rep_28	6.2e-06
ORM2	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
ORM2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Uterus	rep_28	8.7e-06
ORM2	GOBP_Acute_Phase_Response	Human	Breast	rep_1	8.0e-41
ORM2	GOBP_Cytokine_Production	Human	Breast	rep_1	6.5e-12
ORM2	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
ORM2	GOBP_Exocytosis	Human	Breast	rep_1	2.8e-29
ORM2	GOBP_Inflammatory_Response	Human	Breast	rep_1	3.7e-43
ORM2	GOBP_Interleukin_1_Production	Human	Breast	rep_1	1.2e-35
ORM2	GOBP_Myeloid_Leukocyte_Activation	Human	Breast	rep_1	2.2e-37
ORM2	GOBP_Platelet_Degranulation	Human	Breast	rep_1	1.7e-261
ORM2	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Breast	rep_1	6.5e-10
ORM2	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Breast	rep_1	7.3e-07
ORM2	GOBP_Positive_Regulation_Of_Interleukin_1_Production	Human	Breast	rep_1	6.2e-26
ORM2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
ORM2	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
ORM2	GOBP_Acute_Phase_Response	Human	Skin	P10_rep1	1.9e-20
ORM2	GOBP_Platelet_Degranulation	Human	Skin	P10_rep1	6.2e-14
ORM2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Skin	P10_rep2	1.1e-22
ORM2	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
ORM2	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
ORM2	GOBP_Inflammatory_Response	Human	Lung	rep_1	1.4e-10
ORM2	GOBP_Positive_Regulation_Of_Tumor_Necrosis_Factor_Superfamily_Cytokine_Production	Human	Lung	rep_1	2.2e-07
ORM2	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
ORM2	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Lung	rep_2	8.0e-10

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ORM2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ORM2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ORM2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ORM2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ORM2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source