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Spatial pattern gene: EEF1AKMT2 (spascer ID:399818) |
Gene summary for EEF1AKMT2 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | EEF1AKMT2 | Gene ID | 399818 |
| Gene name | EEF1A lysine methyltransferase 2 |
| Synonyms | C10orf138|Efm4|METTL10 |
| Cytomap | 10q26.13 |
| Type of gene | protein-coding |
| Description | EEF1A lysine methyltransferase 2eukaryotic translation elongation factor 1 alpha lysine methyltransferase 2methyltransferase like 10methyltransferase-like protein 10protein-lysine N-methyltransferase METTL10 |
| Modification date | 20220513 |
| UniProtAcc | Q5JPI9 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| EEF1AKMT2 | GO:0005737 | cytoplasm | 21873635 | Component |
| EEF1AKMT2 | GO:0016279 | protein-lysine N-methyltransferase activity | 21873635 | Function |
| EEF1AKMT2 | GO:0018026 | peptidyl-lysine monomethylation | 21873635 | Process |
| EEF1AKMT2 | GO:0018027 | peptidyl-lysine dimethylation | 21873635 | Process |
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Spatial pattern events for EEF1AKMT2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| EEF1AKMT2 | Human | Liver | rep_liver1 | 34417225 | 2.23e-06 |
| EEF1AKMT2 | Human | Breast | CID4535 | 34493872 | 3.21e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver1_H&E  |  |
Breast_CID4535_H&E  |  |
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Spatial pattern pathway has EEF1AKMT2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| EEF1AKMT2 | GOBP_Methylation | Human | Intestine | A3 | 5.9e-09 |
| EEF1AKMT2 | GOBP_Peptidyl_Amino_Acid_Modification | Human | Intestine | A3 | 2.7e-09 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Methylation | Human | Intestine | A3 | 1.9e-08 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Modification | Human | Intestine | A3 | 2.8e-09 |
| EEF1AKMT2 | GOBP_Protein_Methylation | Human | Intestine | A3 | 7.4e-07 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Dimethylation | Human | Intestine | A8 | 2.1e-09 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Monomethylation | Human | Intestine | A8 | 4.7e-10 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Dimethylation | Human | Pancreas | PDAC-A-st2 | 1.1e-10 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Dimethylation | Human | Uterus | rep_1 | 9.9e-06 |
| EEF1AKMT2 | GOBP_Methylation | Human | Uterus | rep_26 | 1.9e-06 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Methylation | Human | Uterus | rep_26 | 6.2e-09 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Modification | Human | Uterus | rep_26 | 2.3e-09 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Monomethylation | Human | Uterus | rep_26 | 4.8e-06 |
| EEF1AKMT2 | GOBP_Protein_Methylation | Human | Uterus | rep_26 | 1.8e-11 |
| EEF1AKMT2 | GOBP_Methylation | Human | Breast | rep_6 | 1.7e-06 |
| EEF1AKMT2 | GOBP_Peptidyl_Amino_Acid_Modification | Human | Breast | rep_6 | 3.8e-05 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Dimethylation | Human | Breast | rep_6 | 1.8e-06 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Methylation | Human | Breast | rep_6 | 5.5e-06 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Modification | Human | Breast | rep_6 | 4.5e-08 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Dimethylation | Human | Skin | P10_rep1 | 1.7e-12 |
| EEF1AKMT2 | GOBP_Peptidyl_Lysine_Methylation | Human | Skin | P10_rep1 | 3.7e-11 |
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EEF1AKMT2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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EEF1AKMT2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for EEF1AKMT2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for EEF1AKMT2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for EEF1AKMT2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
