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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: AGRN (spascer ID:375790)

Gene summary for AGRN

Gene summary

Gene information
	Species	Human
	Gene symbol	AGRN
	Gene ID	375790
	Gene name	agrin
	Synonyms	AGRIN\|CMS8\|CMSPPD
	Cytomap	1p36.33
	Type of gene	protein-coding
	Description	agrinagrin proteoglycan
	Modification date	20220513
	UniProtAcc	O00468

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
AGRN	GO:0007528	neuromuscular junction development	21873635	Process
AGRN	GO:0009887	animal organ morphogenesis	21873635	Process
AGRN	GO:0009888	tissue development	21873635	Process
AGRN	GO:0043113	receptor clustering	21873635	Process

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Spatial pattern events for AGRN

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
AGRN	Human	Bladder	rep_2	34385456	5.89e-06
AGRN	Human	Bladder	rep_3	34385456	2.32e-09
AGRN	Human	Bladder	rep_4	34385456	2.84e-09
AGRN	Human	Intestine	rep_colon1	34417225	1.95e-15
AGRN	Human	Liver	rep_liver1	34417225	1.08e-15
AGRN	Human	Liver	rep_liver2	34417225	6.98e-16
AGRN	Human	Uterus	rep_1	34857954	5.13e-15
AGRN	Human	Uterus	rep_2	34857954	2.55e-15
AGRN	Human	Uterus	rep_3	34857954	1.66e-15
AGRN	Human	Uterus	rep_4	34857954	1.82e-15
AGRN	Human	Breast	A1	34650042	1.26e-07
AGRN	Human	Breast	1160920F	34493872	5.15e-11
AGRN	Human	Breast	CID4465	34493872	4.85e-15
AGRN	Human	Breast	CID4535	34493872	4.28e-13
AGRN	Human	Lung	rep_1	35355018	8.98e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_2_H&E
Bladder_rep_3_H&E
Bladder_rep_4_H&E
Intestine_rep_colon1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_A1_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E
Breast_CID4535_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has AGRN envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
AGRN	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Brain	rep_1	2.8e-23
AGRN	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
AGRN	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
AGRN	GOBP_Neuron_Development	Human	Brain	rep_1	7.4e-34
AGRN	GOBP_Neuron_Differentiation	Human	Brain	rep_1	7.4e-34
AGRN	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
AGRN	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
AGRN	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
AGRN	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
AGRN	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
AGRN	GOBP_Growth	Human	Brain	rep_4	1.0e-14
AGRN	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
AGRN	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
AGRN	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
AGRN	GOBP_Clustering_Of_Voltage_Gated_Sodium_Channels	Human	Bladder	rep_2	6.4e-05
AGRN	GOBP_External_Encapsulating_Structure_Organization	Human	Bladder	rep_2	8.7e-05
AGRN	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Bladder	rep_4	3.0e-06
AGRN	GOBP_Regulation_Of_Neuromuscular_Junction_Development	Human	Bladder	rep_4	3.1e-11
AGRN	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Liver	rep_1	1.0e-70
AGRN	GOBP_Growth	Human	Liver	rep_1	2.1e-52
AGRN	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
AGRN	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
AGRN	GOBP_Neuron_Development	Human	Liver	rep_1	1.5e-73
AGRN	GOBP_Neuron_Differentiation	Human	Liver	rep_1	1.5e-73
AGRN	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
AGRN	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
AGRN	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
AGRN	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
AGRN	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
AGRN	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
AGRN	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
AGRN	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
AGRN	GOBP_Growth	Human	Intestine	rep_colon2	1.5e-57
AGRN	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
AGRN	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
AGRN	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
AGRN	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
AGRN	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
AGRN	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
AGRN	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
AGRN	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
AGRN	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Intestine	A3	1.8e-09
AGRN	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
AGRN	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
AGRN	GOBP_Cell_Junction_Assembly	Human	Intestine	A3	6.2e-12
AGRN	GOBP_Cell_Junction_Organization	Human	Intestine	A3	1.1e-08
AGRN	GOBP_Cell_Projection_Assembly	Human	Intestine	A3	4.9e-09
AGRN	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
AGRN	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
AGRN	GOBP_Clustering_Of_Voltage_Gated_Sodium_Channels	Human	Intestine	A3	3.2e-07
AGRN	GOBP_Developmental_Growth	Human	Intestine	A3	7.3e-10
AGRN	GOBP_Developmental_Maturation	Human	Intestine	A3	2.5e-14
AGRN	GOBP_G_Protein_Coupled_Acetylcholine_Receptor_Signaling_Pathway	Human	Intestine	A3	3.7e-08
AGRN	GOBP_Growth	Human	Intestine	A3	3.3e-16
AGRN	GOBP_Localization_Within_Membrane	Human	Intestine	A3	1.4e-10
AGRN	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
AGRN	GOBP_Membrane_Organization	Human	Intestine	A3	2.7e-18
AGRN	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
AGRN	GOBP_Neuron_Development	Human	Intestine	A3	1.3e-12
AGRN	GOBP_Neuron_Differentiation	Human	Intestine	A3	1.4e-11
AGRN	GOBP_Neuron_Maturation	Human	Intestine	A3	3.6e-12
AGRN	GOBP_Neuronal_Ion_Channel_Clustering	Human	Intestine	A3	2.5e-15
AGRN	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
AGRN	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
AGRN	GOBP_Positive_Regulation_Of_Cell_Junction_Assembly	Human	Intestine	A3	2.9e-11
AGRN	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	1.2e-09
AGRN	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	1.9e-13
AGRN	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
AGRN	GOBP_Positive_Regulation_Of_Developmental_Growth	Human	Intestine	A3	1.1e-10
AGRN	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
AGRN	GOBP_Positive_Regulation_Of_Growth	Human	Intestine	A3	1.3e-11
AGRN	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.8e-12
AGRN	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
AGRN	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
AGRN	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
AGRN	GOBP_Positive_Regulation_Of_Nervous_System_Development	Human	Intestine	A3	1.1e-14
AGRN	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
AGRN	GOBP_Positive_Regulation_Of_Plasma_Membrane_Bounded_Cell_Projection_Assembly	Human	Intestine	A3	3.6e-08
AGRN	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
AGRN	GOBP_Regulation_Of_Cell_Junction_Assembly	Human	Intestine	A3	3.1e-14
AGRN	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Intestine	A3	4.1e-07
AGRN	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
AGRN	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
AGRN	GOBP_Regulation_Of_Developmental_Growth	Human	Intestine	A3	5.3e-18
AGRN	GOBP_Regulation_Of_Growth	Human	Intestine	A3	3.6e-10
AGRN	GOBP_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.0e-12
AGRN	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
AGRN	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
AGRN	GOBP_Regulation_Of_Nervous_System_Development	Human	Intestine	A3	2.8e-11
AGRN	GOBP_Regulation_Of_Neuromuscular_Junction_Development	Human	Intestine	A3	5.3e-08
AGRN	GOBP_Regulation_Of_Synapse_Assembly	Human	Intestine	A3	2.4e-07
AGRN	GOBP_Response_To_Acetylcholine	Human	Intestine	A3	1.3e-08
AGRN	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
AGRN	GOBP_Synapse_Assembly	Human	Intestine	A3	3.1e-18
AGRN	GOBP_Synaptic_Signaling	Human	Intestine	A3	5.0e-10
AGRN	GOBP_Aminoglycan_Biosynthetic_Process	Human	Intestine	A8	6.2e-18
AGRN	GOBP_Aminoglycan_Catabolic_Process	Human	Intestine	A8	5.0e-10
AGRN	GOBP_Anatomical_Structure_Maturation	Human	Intestine	A8	1.0e-12
AGRN	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Intestine	A8	3.2e-10
AGRN	GOBP_Cell_Maturation	Human	Intestine	A8	2.9e-08
AGRN	GOBP_Cellular_Lipid_Metabolic_Process	Human	Intestine	A8	3.8e-13
AGRN	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
AGRN	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Intestine	A8	1.4e-14
AGRN	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
AGRN	GOBP_Neuromuscular_Junction_Development	Human	Intestine	A8	2.2e-08
AGRN	GOBP_Positive_Regulation_Of_Synapse_Assembly	Human	Intestine	A8	3.9e-07
AGRN	GOBP_Postsynaptic_Signal_Transduction	Human	Intestine	A8	1.6e-07
AGRN	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
AGRN	GOBP_Isoprenoid_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.0e-05
AGRN	GOBP_Regulation_Of_Gtpase_Activity	Human	Pancreas	PDAC-B-st1	9.7e-05
AGRN	GOBP_Aminoglycan_Biosynthetic_Process	Human	Pancreas	PDAC-A-st2	8.4e-06
AGRN	GOBP_Neuromuscular_Junction_Development	Human	Pancreas	PDAC-A-st2	7.0e-06
AGRN	GOBP_Neuronal_Ion_Channel_Clustering	Human	Pancreas	PDAC-A-st2	6.0e-05
AGRN	GOBP_G_Protein_Coupled_Acetylcholine_Receptor_Signaling_Pathway	Human	Uterus	rep_1	4.6e-08
AGRN	GOBP_Regulation_Of_Neuromuscular_Junction_Development	Human	Uterus	rep_1	4.7e-14
AGRN	GOBP_Regulation_Of_Synapse_Assembly	Human	Uterus	rep_2	1.5e-06
AGRN	GOBP_Anatomical_Structure_Maturation	Human	Uterus	rep_26	1.8e-09
AGRN	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Uterus	rep_26	3.5e-11
AGRN	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Uterus	rep_26	5.1e-11
AGRN	GOBP_Cell_Maturation	Human	Uterus	rep_26	4.6e-09
AGRN	GOBP_Developmental_Growth	Human	Uterus	rep_26	3.8e-06
AGRN	GOBP_Developmental_Maturation	Human	Uterus	rep_26	1.1e-06
AGRN	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Uterus	rep_26	3.5e-06
AGRN	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
AGRN	GOBP_Neuronal_Ion_Channel_Clustering	Human	Uterus	rep_26	7.8e-23
AGRN	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
AGRN	GOBP_Postsynaptic_Signal_Transduction	Human	Uterus	rep_26	2.1e-06
AGRN	GOBP_Regulation_Of_Developmental_Growth	Human	Uterus	rep_26	6.9e-10
AGRN	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
AGRN	GOBP_Regulation_Of_Synapse_Structure_Or_Activity	Human	Uterus	rep_26	2.3e-07
AGRN	GOBP_Response_To_Acetylcholine	Human	Uterus	rep_26	5.3e-06
AGRN	GOBP_Synaptic_Signaling	Human	Uterus	rep_26	3.3e-08
AGRN	GOBP_Terpenoid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
AGRN	GOBP_Neuron_Maturation	Human	Uterus	rep_29	3.8e-07
AGRN	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
AGRN	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
AGRN	GOBP_Aminoglycan_Biosynthetic_Process	Human	Breast	rep_1	1.4e-24
AGRN	GOBP_Aminoglycan_Metabolic_Process	Human	Breast	rep_1	2.4e-24
AGRN	GOBP_Animal_Organ_Morphogenesis	Human	Breast	rep_1	5.4e-25
AGRN	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Breast	rep_1	2.1e-06
AGRN	GOBP_Cell_Junction_Assembly	Human	Breast	rep_1	4.4e-63
AGRN	GOBP_Cell_Junction_Organization	Human	Breast	rep_1	3.0e-10
AGRN	GOBP_Cell_Projection_Assembly	Human	Breast	rep_1	1.9e-26
AGRN	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
AGRN	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
AGRN	GOBP_Clustering_Of_Voltage_Gated_Sodium_Channels	Human	Breast	rep_1	1.8e-09
AGRN	GOBP_Cytoskeleton_Organization	Human	Breast	rep_1	1.3e-22
AGRN	GOBP_External_Encapsulating_Structure_Organization	Human	Breast	rep_1	2.8e-108
AGRN	GOBP_G_Protein_Coupled_Acetylcholine_Receptor_Signaling_Pathway	Human	Breast	rep_1	4.1e-30
AGRN	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Breast	rep_1	3.6e-09
AGRN	GOBP_Localization_Within_Membrane	Human	Breast	rep_1	1.3e-07
AGRN	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
AGRN	GOBP_Neuron_Development	Human	Breast	rep_1	2.5e-26
AGRN	GOBP_Neuron_Differentiation	Human	Breast	rep_1	1.1e-16
AGRN	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	1.6e-25
AGRN	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	3.5e-04
AGRN	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
AGRN	GOBP_Positive_Regulation_Of_Developmental_Growth	Human	Breast	rep_1	5.6e-64
AGRN	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
AGRN	GOBP_Positive_Regulation_Of_Filopodium_Assembly	Human	Breast	rep_1	3.7e-11
AGRN	GOBP_Positive_Regulation_Of_Growth	Human	Breast	rep_1	3.1e-25
AGRN	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	1.4e-13
AGRN	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
AGRN	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
AGRN	GOBP_Positive_Regulation_Of_Nervous_System_Development	Human	Breast	rep_1	5.9e-13
AGRN	GOBP_Positive_Regulation_Of_Synapse_Assembly	Human	Breast	rep_1	4.5e-20
AGRN	GOBP_Postsynaptic_Signal_Transduction	Human	Breast	rep_1	1.9e-72
AGRN	GOBP_Receptor_Clustering	Human	Breast	rep_1	3.5e-61
AGRN	GOBP_Regulation_Of_Cell_Junction_Assembly	Human	Breast	rep_1	8.1e-17
AGRN	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Breast	rep_1	6.5e-29
AGRN	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
AGRN	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
AGRN	GOBP_Regulation_Of_Developmental_Growth	Human	Breast	rep_1	1.2e-04
AGRN	GOBP_Regulation_Of_Growth	Human	Breast	rep_1	2.3e-04
AGRN	GOBP_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	9.6e-08
AGRN	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
AGRN	GOBP_Regulation_Of_Nervous_System_Development	Human	Breast	rep_1	2.9e-16
AGRN	GOBP_Response_To_Acetylcholine	Human	Breast	rep_1	5.2e-129
AGRN	GOBP_Synapse_Organization	Human	Breast	rep_1	3.0e-09
AGRN	GOBP_Synaptic_Signaling	Human	Breast	rep_1	3.5e-04
AGRN	GOBP_Anatomical_Structure_Maturation	Human	Breast	rep_5	9.1e-14
AGRN	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Breast	rep_5	1.1e-09
AGRN	GOBP_Cell_Maturation	Human	Breast	rep_5	1.3e-19
AGRN	GOBP_Cellular_Lipid_Metabolic_Process	Human	Breast	rep_5	2.6e-07
AGRN	GOBP_Cellular_Response_To_Nitrogen_Compound	Human	Breast	rep_5	4.4e-13
AGRN	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
AGRN	GOBP_Developmental_Growth	Human	Breast	rep_5	1.6e-08
AGRN	GOBP_Developmental_Maturation	Human	Breast	rep_5	2.3e-12
AGRN	GOBP_Growth	Human	Breast	rep_5	5.4e-12
AGRN	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
AGRN	GOBP_Neuromuscular_Junction_Development	Human	Breast	rep_5	1.2e-12
AGRN	GOBP_Neuron_Maturation	Human	Breast	rep_5	4.8e-06
AGRN	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
AGRN	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
AGRN	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
AGRN	GOBP_Regulation_Of_Filopodium_Assembly	Human	Breast	rep_5	7.6e-12
AGRN	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
AGRN	GOBP_Regulation_Of_Neuromuscular_Junction_Development	Human	Breast	rep_5	1.1e-17
AGRN	GOBP_Regulation_Of_Synapse_Assembly	Human	Breast	rep_5	2.1e-05
AGRN	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
AGRN	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
AGRN	GOBP_Synapse_Assembly	Human	Breast	rep_5	3.2e-05
AGRN	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
AGRN	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
AGRN	GOBP_Isoprenoid_Metabolic_Process	Human	Breast	rep_6	3.7e-11
AGRN	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
AGRN	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
AGRN	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
AGRN	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
AGRN	GOBP_Regulation_Of_Synapse_Structure_Or_Activity	Human	Breast	rep_6	1.2e-04
AGRN	GOBP_Terpenoid_Metabolic_Process	Human	Breast	rep_6	1.1e-10
AGRN	GOBP_Positive_Regulation_Of_Developmental_Growth	Human	Skin	P2_rep2	6.1e-10
AGRN	GOBP_Positive_Regulation_Of_Growth	Human	Skin	P2_rep3	2.6e-09
AGRN	GOBP_Regulation_Of_Neuromuscular_Junction_Development	Human	Skin	P5_rep1	2.4e-08
AGRN	GOBP_Positive_Regulation_Of_Synapse_Assembly	Human	Skin	P5_rep3	1.2e-14
AGRN	GOBP_Cytoskeleton_Organization	Human	Skin	P9_rep3	3.1e-12
AGRN	GOBP_G_Protein_Coupled_Acetylcholine_Receptor_Signaling_Pathway	Human	Skin	P10_rep1	1.2e-16
AGRN	GOBP_Postsynaptic_Signal_Transduction	Human	Skin	P10_rep1	2.4e-20
AGRN	GOBP_Response_To_Acetylcholine	Human	Skin	P10_rep1	1.0e-13
AGRN	GOBP_Receptor_Clustering	Human	Lung	rep_1	1.3e-07
AGRN	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
AGRN	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08
AGRN	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Human	Lung	rep_2	4.8e-08
AGRN	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07
AGRN	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07

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AGRN function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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AGRN function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
AGRN	ITGB1	AGRN_ITGB1	Skin	mel2_rep2
AGRN	ATP1A3	AGRN_ATP1A3	Skin	mel2_rep2
AGRN	LRP1	AGRN_LRP1	Skin	mel2_rep2
AGRN	LRP2	AGRN_LRP2	Skin	mel2_rep2
AGRN	MUSK	AGRN_MUSK	Skin	mel2_rep2
AGRN	LRP4	AGRN_LRP4	Skin	mel2_rep2
AGRN	LRP1	AGRN_LRP1	Intestine	A1
AGRN	ATP1A3	AGRN_ATP1A3	Brain	rep_3

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Transcription factor for AGRN envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for AGRN

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for AGRN

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
AGRN	C3808739	MYASTHENIC SYNDROME, CONGENITAL, 8	3	GENOMICS_ENGLAND;UNIPROT
AGRN	C0751883	Congenital Myasthenic Syndromes, Postsynaptic	2	CTD_human;ORPHANET
AGRN	C0751884	Congenital Myasthenic Syndromes, Presynaptic	2	CTD_human;ORPHANET
AGRN	C0023467	Leukemia, Myelocytic, Acute	1	CTD_human
AGRN	C0026998	Acute Myeloid Leukemia, M1	1	CTD_human
AGRN	C0751882	Myasthenic Syndromes, Congenital	1	CTD_human;GENOMICS_ENGLAND
AGRN	C1879321	Acute Myeloid Leukemia (AML-M2)	1	CTD_human