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Spatial pattern gene: SWI5 (spascer ID:375757) |
Gene summary for SWI5 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | SWI5 | Gene ID | 375757 |
| Gene name | SWI5 homologous recombination repair protein |
| Synonyms | C9orf119|SAE3 |
| Cytomap | 9q34.11 |
| Type of gene | protein-coding |
| Description | DNA repair protein SWI5 homologHBV DNAPTP1-transactivated protein ASWI5 recombination repair homologprotein SAE3 homolog |
| Modification date | 20220513 |
| UniProtAcc | Q1ZZU3 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| SWI5 | GO:0000724 | double-strand break repair via homologous recombination | 21873635 | Process |
| SWI5 | GO:0032798 | Swi5-Sfr1 complex | 21873635 | Component |
| SWI5 | GO:0034974 | Swi5-Swi2 complex | 21873635 | Component |
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Spatial pattern events for SWI5 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| SWI5 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| SWI5 | Human | Uterus | rep_1 | 34857954 | 2.57e-06 |
| SWI5 | Human | Uterus | rep_3 | 34857954 | 4.72e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver1_H&E  |  |
Uterus_rep_1_H&E  |  |
Uterus_rep_3_H&E  |  |
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Spatial pattern pathway has SWI5 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| SWI5 | GOBP_Cellular_Response_To_Abiotic_Stimulus | Human | Bladder | rep_2 | 7.0e-07 |
| SWI5 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Human | Intestine | A3 | 6.6e-16 |
| SWI5 | GOBP_Cellular_Response_To_Radiation | Human | Intestine | A3 | 6.7e-10 |
| SWI5 | GOBP_Dna_Metabolic_Process | Human | Intestine | A3 | 1.2e-09 |
| SWI5 | GOBP_Dna_Repair | Human | Intestine | A3 | 4.4e-09 |
| SWI5 | GOBP_Double_Strand_Break_Repair | Human | Intestine | A3 | 3.1e-09 |
| SWI5 | GOBP_Response_To_Abiotic_Stimulus | Human | Intestine | A3 | 5.3e-18 |
| SWI5 | GOBP_Response_To_Radiation | Human | Intestine | A3 | 6.3e-07 |
| SWI5 | GOBP_Cellular_Response_To_Abiotic_Stimulus | Human | Intestine | A8 | 2.5e-11 |
| SWI5 | GOBP_Cellular_Response_To_Ionizing_Radiation | Human | Intestine | A8 | 1.7e-19 |
| SWI5 | GOBP_Response_To_Ionizing_Radiation | Human | Intestine | A8 | 4.7e-09 |
| SWI5 | GOBP_Cellular_Response_To_Ionizing_Radiation | Human | Pancreas | PDAC-B-st1 | 7.2e-05 |
| SWI5 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Human | Uterus | rep_26 | 2.4e-07 |
| SWI5 | GOBP_Recombinational_Repair | Human | Breast | rep_1 | 2.9e-09 |
| SWI5 | GOBP_Response_To_Abiotic_Stimulus | Human | Breast | rep_1 | 2.6e-19 |
| SWI5 | GOBP_Cellular_Response_To_Abiotic_Stimulus | Human | Breast | rep_5 | 1.3e-06 |
| SWI5 | GOBP_Response_To_Radiation | Human | Breast | rep_5 | 3.8e-06 |
| SWI5 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Human | Breast | rep_6 | 6.0e-06 |
| SWI5 | GOBP_Cellular_Response_To_Ionizing_Radiation | Human | Breast | rep_6 | 3.4e-10 |
| SWI5 | GOBP_Cellular_Response_To_Radiation | Human | Breast | rep_6 | 5.1e-06 |
| SWI5 | GOBP_Dna_Metabolic_Process | Human | Breast | rep_6 | 1.4e-10 |
| SWI5 | GOBP_Dna_Recombination | Human | Breast | rep_6 | 1.4e-06 |
| SWI5 | GOBP_Dna_Repair | Human | Breast | rep_6 | 1.0e-09 |
| SWI5 | GOBP_Double_Strand_Break_Repair | Human | Breast | rep_6 | 2.0e-09 |
| SWI5 | GOBP_Response_To_Ionizing_Radiation | Human | Breast | rep_6 | 1.1e-11 |
| SWI5 | GOBP_Dna_Repair | Human | Skin | P5_rep1 | 1.7e-08 |
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SWI5 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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SWI5 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for SWI5 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for SWI5 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SWI5 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
