|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: ASPG (spascer ID:374569) |
Gene summary for ASPG |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | ASPG | Gene ID | 374569 |
| Gene name | asparaginase |
| Synonyms | C14orf76|GPA/WT|LYSOLP |
| Cytomap | 14q32.33 |
| Type of gene | protein-coding |
| Description | 60 kDa lysophospholipaseasparaginase homologlysophospholipase-transacylasewild-type L-asparaginase |
| Modification date | 20220513 |
| UniProtAcc | Q86U10 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| ASPG | GO:0004067 | asparaginase activity | 21873635 | Function |
Top |
Spatial pattern events for ASPG |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| ASPG | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| ASPG | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| ASPG | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| ASPG | Human | Liver | rep_liver3 | 34417225 | 3.51e-15 |
| ASPG | Human | Intestine | A4 | 33406409 | 7.35e-15 |
| ASPG | Human | Intestine | A8 | 33406409 | 4.31e-09 |
| ASPG | Human | Intestine | A9 | 33406409 | 4.87e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver3_H&E  |  |
Intestine_A4_H&E  |  |
Intestine_A8_H&E  |  |
Intestine_A9_H&E  |  |
Top |
Spatial pattern pathway has ASPG envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| ASPG | GOBP_Lipid_Metabolic_Process | Human | Brain | rep_1 | 2.8e-23 |
| ASPG | GOBP_Lipid_Metabolic_Process | Human | Liver | rep_1 | 1.0e-70 |
| ASPG | GOBP_Cellular_Amino_Acid_Biosynthetic_Process | Human | Intestine | A8 | 3.7e-12 |
| ASPG | GOBP_Cellular_Amino_Acid_Metabolic_Process | Human | Intestine | A8 | 5.3e-13 |
| ASPG | GOBP_Lipid_Catabolic_Process | Human | Intestine | A8 | 3.2e-08 |
| ASPG | GOBP_Lipid_Metabolic_Process | Human | Intestine | A8 | 1.1e-11 |
| ASPG | GOBP_Organic_Acid_Biosynthetic_Process | Human | Intestine | A8 | 2.1e-08 |
| ASPG | GOBP_Organic_Acid_Metabolic_Process | Human | Intestine | A8 | 2.5e-18 |
| ASPG | GOBP_Small_Molecule_Biosynthetic_Process | Human | Intestine | A8 | 1.0e-14 |
| ASPG | GOBP_Small_Molecule_Metabolic_Process | Human | Intestine | A8 | 2.1e-15 |
| ASPG | GOBP_Cellular_Amino_Acid_Metabolic_Process | Human | Pancreas | PDAC-A-st2 | 9.6e-05 |
| ASPG | GOBP_Organic_Acid_Biosynthetic_Process | Human | Uterus | rep_26 | 2.3e-06 |
| ASPG | GOBP_Organic_Acid_Metabolic_Process | Human | Uterus | rep_26 | 4.9e-06 |
| ASPG | GOBP_Small_Molecule_Biosynthetic_Process | Human | Uterus | rep_26 | 5.8e-09 |
| ASPG | GOBP_Lipid_Metabolic_Process | Human | Breast | rep_5 | 2.9e-06 |
| ASPG | GOBP_Organic_Acid_Biosynthetic_Process | Human | Breast | rep_5 | 3.5e-09 |
| ASPG | GOBP_Cellular_Amino_Acid_Metabolic_Process | Human | Breast | rep_6 | 1.0e-10 |
| ASPG | GOBP_Lipid_Catabolic_Process | Human | Breast | rep_6 | 2.9e-05 |
| ASPG | GOBP_Organic_Acid_Metabolic_Process | Human | Breast | rep_6 | 6.7e-05 |
| ASPG | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Human | Breast | rep_6 | 1.2e-09 |
| ASPG | GOBP_Small_Molecule_Biosynthetic_Process | Human | Breast | rep_6 | 1.0e-06 |
| ASPG | GOBP_Small_Molecule_Metabolic_Process | Human | Breast | rep_6 | 5.5e-09 |
| ASPG | GOBP_Lipid_Catabolic_Process | Human | Lung | rep_2 | 1.4e-09 |
Top |
ASPG function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
ASPG function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for ASPG envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for ASPG |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| ASPG | Q86U10 | DB00721 | Procaine | 60 kDa lysophospholipase | SmallMoleculeDrug | approved|investigational|vet_approved |
Top |
Related Diseases for ASPG |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| ASPG | C0002792 | anaphylaxis | 1 | CTD_human |
| ASPG | C0002871 | Anemia | 1 | CTD_human |
| ASPG | C0008350 | Cholelithiasis | 1 | CTD_human |
| ASPG | C0015967 | Fever | 1 | CTD_human |
| ASPG | C0018965 | Hematuria | 1 | CTD_human |
| ASPG | C0023530 | Leukopenia | 1 | CTD_human |
| ASPG | C0040034 | Thrombocytopenia | 1 | CTD_human |
| ASPG | C0042963 | Vomiting | 1 | CTD_human |
| ASPG | C0701818 | Choledocholithiasis | 1 | CTD_human |
| ASPG | C2239176 | Liver carcinoma | 1 | CTD_human |
