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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: ACSM2B (spascer ID:348158)

Gene summary for ACSM2B

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

ACSM2B

Gene ID

348158

Gene nameacyl-CoA synthetase medium chain family member 2B
SynonymsACSM2|HXMA|HYST1046
Cytomap16p12.3
Type of geneprotein-coding
Descriptionacyl-coenzyme A synthetase ACSM2B, mitochondrialacyl-CoA synthetase medium-chain family member 2benzoate--CoA ligasebutyrate--CoA ligase 2Bbutyryl-coenzyme A synthetase 2Bmiddle-chain acyl-CoA synthetase 2Bxenobiotic/medium-chain fatty acid-CoA liga
Modification date20220513
UniProtAcc

Q68CK6


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
ACSM2B

GO:0004321

fatty-acyl-CoA synthase activity

21873635

Function
ACSM2B

GO:0005759

mitochondrial matrix

21873635

Component
ACSM2B

GO:0006633

fatty acid biosynthetic process

21873635

Process
ACSM2B

GO:0006637

acyl-CoA metabolic process

21873635

Process
ACSM2B

GO:0015645

fatty acid ligase activity

21873635

Function

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Spatial pattern events for ACSM2B

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
ACSM2BHumanLiverrep_liver1 344172253.57e-15
ACSM2BHumanLiverrep_liver2 344172256.98e-16
ACSM2BHumanLiverrep_liver3 344172256.13e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Liver_rep_liver3_H&E
boxplot

boxplot


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Spatial pattern pathway has ACSM2B envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
ACSM2BGOBP_Lipid_Metabolic_ProcessHumanBrainrep_1 2.8e-23
ACSM2BGOBP_Lipid_Metabolic_ProcessHumanLiverrep_1 1.0e-70
ACSM2BGOBP_Carbohydrate_Derivative_Metabolic_ProcessHumanIntestineA3 3.3e-11
ACSM2BGOBP_Lipid_Biosynthetic_ProcessHumanIntestineA3 5.0e-07
ACSM2BGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessHumanIntestineA3 9.9e-10
ACSM2BGOBP_Organophosphate_Metabolic_ProcessHumanIntestineA3 4.4e-13
ACSM2BGOBP_Purine_Containing_Compound_Metabolic_ProcessHumanIntestineA3 7.9e-07
ACSM2BGOBP_Response_To_Xenobiotic_StimulusHumanIntestineA3 2.5e-09
ACSM2BGOBP_Cellular_Lipid_Metabolic_ProcessHumanIntestineA8 3.8e-13
ACSM2BGOBP_Fatty_Acid_Metabolic_ProcessHumanIntestineA8 7.3e-13
ACSM2BGOBP_Lipid_Metabolic_ProcessHumanIntestineA8 1.1e-11
ACSM2BGOBP_Long_Chain_Fatty_Acid_Metabolic_ProcessHumanIntestineA8 8.2e-09
ACSM2BGOBP_Monocarboxylic_Acid_Metabolic_ProcessHumanIntestineA8 7.3e-16
ACSM2BGOBP_Nucleoside_Bisphosphate_Metabolic_ProcessHumanIntestineA8 3.8e-09
ACSM2BGOBP_Organic_Acid_Biosynthetic_ProcessHumanIntestineA8 2.1e-08
ACSM2BGOBP_Organic_Acid_Metabolic_ProcessHumanIntestineA8 2.5e-18
ACSM2BGOBP_Small_Molecule_Biosynthetic_ProcessHumanIntestineA8 1.0e-14
ACSM2BGOBP_Small_Molecule_Metabolic_ProcessHumanIntestineA8 2.1e-15
ACSM2BGOBP_Sulfur_Compound_Metabolic_ProcessHumanIntestineA8 2.5e-14
ACSM2BGOBP_Thioester_Metabolic_ProcessHumanIntestineA8 4.0e-09
ACSM2BGOBP_Fatty_Acid_Biosynthetic_ProcessHumanUterusrep_26 9.2e-10
ACSM2BGOBP_Fatty_Acid_Metabolic_ProcessHumanUterusrep_26 1.3e-06
ACSM2BGOBP_Long_Chain_Fatty_Acid_Metabolic_ProcessHumanUterusrep_26 1.9e-09
ACSM2BGOBP_Monocarboxylic_Acid_Biosynthetic_ProcessHumanUterusrep_26 1.0e-07
ACSM2BGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessHumanUterusrep_26 2.4e-06
ACSM2BGOBP_Nucleoside_Bisphosphate_Metabolic_ProcessHumanUterusrep_26 9.1e-11
ACSM2BGOBP_Organic_Acid_Biosynthetic_ProcessHumanUterusrep_26 2.3e-06
ACSM2BGOBP_Organic_Acid_Metabolic_ProcessHumanUterusrep_26 4.9e-06
ACSM2BGOBP_Purine_Containing_Compound_Metabolic_ProcessHumanUterusrep_26 2.0e-06
ACSM2BGOBP_Small_Molecule_Biosynthetic_ProcessHumanUterusrep_26 5.8e-09
ACSM2BGOBP_Sulfur_Compound_Metabolic_ProcessHumanUterusrep_26 8.8e-08
ACSM2BGOBP_Thioester_Metabolic_ProcessHumanUterusrep_26 2.5e-14
ACSM2BGOBP_Cellular_Lipid_Metabolic_ProcessHumanBreastrep_5 2.6e-07
ACSM2BGOBP_Fatty_Acid_Biosynthetic_ProcessHumanBreastrep_5 2.8e-12
ACSM2BGOBP_Fatty_Acid_Metabolic_ProcessHumanBreastrep_5 1.2e-06
ACSM2BGOBP_Lipid_Biosynthetic_ProcessHumanBreastrep_5 7.0e-04
ACSM2BGOBP_Lipid_Metabolic_ProcessHumanBreastrep_5 2.9e-06
ACSM2BGOBP_Monocarboxylic_Acid_Biosynthetic_ProcessHumanBreastrep_5 2.9e-17
ACSM2BGOBP_Organic_Acid_Biosynthetic_ProcessHumanBreastrep_5 3.5e-09
ACSM2BGOBP_Response_To_Xenobiotic_StimulusHumanBreastrep_5 2.9e-05
ACSM2BGOBP_Carbohydrate_Derivative_Metabolic_ProcessHumanBreastrep_6 6.1e-07
ACSM2BGOBP_Cellular_Amide_Metabolic_ProcessHumanBreastrep_6 5.6e-05
ACSM2BGOBP_Long_Chain_Fatty_Acid_Metabolic_ProcessHumanBreastrep_6 6.3e-10
ACSM2BGOBP_Monocarboxylic_Acid_Metabolic_ProcessHumanBreastrep_6 6.1e-07
ACSM2BGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessHumanBreastrep_6 1.7e-10
ACSM2BGOBP_Nucleoside_Bisphosphate_Metabolic_ProcessHumanBreastrep_6 1.6e-07
ACSM2BGOBP_Organic_Acid_Metabolic_ProcessHumanBreastrep_6 6.7e-05
ACSM2BGOBP_Organophosphate_Metabolic_ProcessHumanBreastrep_6 1.0e-12
ACSM2BGOBP_Purine_Containing_Compound_Metabolic_ProcessHumanBreastrep_6 2.5e-09
ACSM2BGOBP_Small_Molecule_Biosynthetic_ProcessHumanBreastrep_6 1.0e-06
ACSM2BGOBP_Small_Molecule_Metabolic_ProcessHumanBreastrep_6 5.5e-09
ACSM2BGOBP_Sulfur_Compound_Metabolic_ProcessHumanBreastrep_6 3.0e-10
ACSM2BGOBP_Thioester_Metabolic_ProcessHumanBreastrep_6 2.5e-07
ACSM2BGOBP_Fatty_Acid_Biosynthetic_ProcessHumanLungrep_2 7.8e-07

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ACSM2B function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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ACSM2B function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for ACSM2B envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for ACSM2B

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACSM2B

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource