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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: HIPK2 (spascer ID:28996)

Gene summary for HIPK2

Gene summary

Gene information
	Species	Human
	Gene symbol	HIPK2
	Gene ID	28996
	Gene name	homeodomain interacting protein kinase 2
	Synonyms	PRO0593
	Cytomap	7q34
	Type of gene	protein-coding
	Description	homeodomain-interacting protein kinase 2hHIPk2
	Modification date	20220513
	UniProtAcc	Q9H2X6

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
HIPK2	GO:0003713	transcription coactivator activity	21873635	Function
HIPK2	GO:0003714	transcription corepressor activity	21873635	Function
HIPK2	GO:0004674	protein serine/threonine kinase activity	21873635	Function
HIPK2	GO:0004713	protein tyrosine kinase activity	21873635	Function
HIPK2	GO:0005634	nucleus	21873635	Component
HIPK2	GO:0005737	cytoplasm	21873635	Component
HIPK2	GO:0007224	smoothened signaling pathway	21873635	Process
HIPK2	GO:0016605	PML body	21873635	Component
HIPK2	GO:0018105	peptidyl-serine phosphorylation	21873635	Process
HIPK2	GO:0018107	peptidyl-threonine phosphorylation	21873635	Process
HIPK2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	21873635	Process
HIPK2	GO:0045944	positive regulation of transcription by RNA polymerase II	21873635	Process
HIPK2	GO:0046332	SMAD binding	21873635	Function

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Spatial pattern events for HIPK2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
HIPK2	Human	Brain	rep_1	33558695	5.52e-15
HIPK2	Human	Brain	rep_3	33558695	4.93e-15
HIPK2	Human	Brain	rep_4	33558695	6.08e-15
HIPK2	Human	Brain	rep_9	33558695	3.01e-15
HIPK2	Human	Brain	rep_10	33558695	3.23e-15
HIPK2	Human	Brain	rep_11	33558695	3.36e-15
HIPK2	Human	Brain	rep_12	33558695	3.65e-15
HIPK2	Human	Intestine	rep_colon1	34417225	7.99e-14
HIPK2	Human	Liver	rep_liver1	34417225	1.08e-15
HIPK2	Human	Liver	rep_liver2	34417225	6.98e-16
HIPK2	Human	Breast	CID44971	34493872	6.19e-08
HIPK2	Human	Skin	P5_rep1	32946785	2.76e-06
HIPK2	Human	Skin	P5_rep2	32946785	6.43e-12
HIPK2	Human	Skin	P9_rep1	32946785	2.00e-09
HIPK2	Human	Skin	P9_rep2	32946785	1.53e-14
HIPK2	Human	Skin	mel1_rep1	30154148	1.22e-13
HIPK2	Human	Skin	mel1_rep2	30154148	2.48e-14
HIPK2	Human	Skin	mel2_rep1	30154148	7.75e-07
HIPK2	Human	Skin	mel2_rep2	30154148	3.28e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Intestine_rep_colon1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Breast_CID44971_H&E
Skin_P5_rep1_H&E
Skin_P5_rep2_H&E
Skin_P9_rep1_H&E
Skin_P9_rep2_H&E

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Spatial pattern pathway has HIPK2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
HIPK2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Brain	rep_1	2.3e-68
HIPK2	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	7.4e-34
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis	Human	Brain	rep_1	2.8e-23
HIPK2	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
HIPK2	GOBP_Neuron_Differentiation	Human	Brain	rep_1	7.4e-34
HIPK2	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Brain	rep_1	1.3e-60
HIPK2	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	3.1e-68
HIPK2	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
HIPK2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
HIPK2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	2.8e-23
HIPK2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
HIPK2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	2.8e-23
HIPK2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	2.8e-23
HIPK2	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
HIPK2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	1.2e-64
HIPK2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	7.4e-34
HIPK2	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
HIPK2	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	7.4e-34
HIPK2	GOBP_Regulation_Of_Proteolysis	Human	Brain	rep_1	4.4e-07
HIPK2	GOBP_Regulation_Of_Response_To_Stress	Human	Brain	rep_1	4.6e-05
HIPK2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Blood_Vessel_Morphogenesis	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
HIPK2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Regulation_Of_Vasculature_Development	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
HIPK2	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
HIPK2	GOBP_Blood_Vessel_Morphogenesis	Human	Bladder	rep_2	9.4e-07
HIPK2	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
HIPK2	GOBP_Dna_Damage_Response_Signal_Transduction_Resulting_In_Transcription	Human	Bladder	rep_2	1.9e-05
HIPK2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Bladder	rep_2	1.3e-05
HIPK2	GOBP_Iris_Morphogenesis	Human	Bladder	rep_2	3.0e-05
HIPK2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Human	Bladder	rep_2	3.4e-19
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Bladder	rep_2	2.7e-09
HIPK2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Bladder	rep_2	2.6e-04
HIPK2	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Bladder	rep_2	1.6e-04
HIPK2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Human	Bladder	rep_2	2.3e-05
HIPK2	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Bladder	rep_2	6.7e-07
HIPK2	GOBP_Regulation_Of_Vasculature_Development	Human	Bladder	rep_2	4.2e-09
HIPK2	GOBP_Response_To_Growth_Factor	Human	Bladder	rep_2	1.2e-08
HIPK2	GOBP_Response_To_Transforming_Growth_Factor_Beta	Human	Bladder	rep_2	1.5e-11
HIPK2	GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Bladder	rep_2	2.2e-29
HIPK2	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Bladder	rep_2	2.5e-23
HIPK2	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
HIPK2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Blood_Vessel_Morphogenesis	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Liver	rep_1	8.8e-90
HIPK2	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Liver	rep_1	2.8e-53
HIPK2	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Neuron_Differentiation	Human	Liver	rep_1	1.5e-73
HIPK2	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Liver	rep_1	2.0e-49
HIPK2	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
HIPK2	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
HIPK2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
HIPK2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
HIPK2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
HIPK2	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
HIPK2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
HIPK2	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
HIPK2	GOBP_Regulation_Of_Proteolysis	Human	Liver	rep_1	1.1e-67
HIPK2	GOBP_Regulation_Of_Response_To_Stress	Human	Liver	rep_1	5.3e-67
HIPK2	GOBP_Regulation_Of_Vasculature_Development	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
HIPK2	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
HIPK2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Intestine	rep_colon2	5.0e-29
HIPK2	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	rep_colon2	2.9e-50
HIPK2	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	3.4e-10
HIPK2	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
HIPK2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	2.4e-25
HIPK2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
HIPK2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
HIPK2	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
HIPK2	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
HIPK2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	rep_colon4	9.0e-12
HIPK2	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
HIPK2	GOBP_Regulation_Of_Proteolysis	Human	Intestine	rep_colon4	1.2e-51
HIPK2	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	rep_colon4	2.2e-52
HIPK2	GOBP_Regulation_Of_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
HIPK2	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
HIPK2	GOBP_Adult_Locomotory_Behavior	Human	Intestine	A3	2.6e-12
HIPK2	GOBP_Anterior_Posterior_Pattern_Specification	Human	Intestine	A3	4.1e-08
HIPK2	GOBP_Apoptotic_Signaling_Pathway	Human	Intestine	A3	7.0e-12
HIPK2	GOBP_Behavior	Human	Intestine	A3	1.8e-11
HIPK2	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Intestine	A3	3.9e-17
HIPK2	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
HIPK2	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	A3	4.7e-07
HIPK2	GOBP_Camera_Type_Eye_Development	Human	Intestine	A3	9.7e-08
HIPK2	GOBP_Camera_Type_Eye_Morphogenesis	Human	Intestine	A3	5.4e-10
HIPK2	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
HIPK2	GOBP_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-12
HIPK2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	6.6e-16
HIPK2	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Intestine	A3	2.0e-11
HIPK2	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
HIPK2	GOBP_Embryo_Development	Human	Intestine	A3	2.4e-07
HIPK2	GOBP_Embryonic_Morphogenesis	Human	Intestine	A3	1.3e-11
HIPK2	GOBP_Embryonic_Organ_Development	Human	Intestine	A3	1.4e-10
HIPK2	GOBP_Embryonic_Organ_Morphogenesis	Human	Intestine	A3	1.5e-09
HIPK2	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Intestine	A3	7.2e-10
HIPK2	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
HIPK2	GOBP_Immune_System_Development	Human	Intestine	A3	4.3e-10
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Intestine	A3	2.5e-16
HIPK2	GOBP_Jnk_Cascade	Human	Intestine	A3	3.8e-08
HIPK2	GOBP_Locomotory_Behavior	Human	Intestine	A3	8.3e-10
HIPK2	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
HIPK2	GOBP_Mapk_Cascade	Human	Intestine	A3	1.1e-12
HIPK2	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Intestine	A3	7.7e-11
HIPK2	GOBP_Myeloid_Cell_Homeostasis	Human	Intestine	A3	1.0e-07
HIPK2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Intestine	A3	5.9e-17
HIPK2	GOBP_Negative_Regulation_Of_Catabolic_Process	Human	Intestine	A3	5.0e-10
HIPK2	GOBP_Negative_Regulation_Of_Cell_Death	Human	Intestine	A3	5.8e-14
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Intestine	A3	9.0e-12
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Apoptotic_Process	Human	Intestine	A3	2.9e-13
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Death	Human	Intestine	A3	9.1e-14
HIPK2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
HIPK2	GOBP_Negative_Regulation_Of_Protein_Catabolic_Process	Human	Intestine	A3	3.2e-07
HIPK2	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	7.8e-11
HIPK2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Intestine	A3	6.0e-11
HIPK2	GOBP_Negative_Regulation_Of_Signaling	Human	Intestine	A3	4.9e-15
HIPK2	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	1.9e-15
HIPK2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Intestine	A3	1.1e-12
HIPK2	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
HIPK2	GOBP_Neuron_Apoptotic_Process	Human	Intestine	A3	7.8e-11
HIPK2	GOBP_Neuron_Death	Human	Intestine	A3	2.4e-14
HIPK2	GOBP_Neuron_Differentiation	Human	Intestine	A3	1.4e-11
HIPK2	GOBP_Nuclear_Body_Organization	Human	Intestine	A3	3.6e-10
HIPK2	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
HIPK2	GOBP_Pattern_Specification_Process	Human	Intestine	A3	4.9e-07
HIPK2	GOBP_Peptidyl_Amino_Acid_Modification	Human	Intestine	A3	2.7e-09
HIPK2	GOBP_Peptidyl_Serine_Modification	Human	Intestine	A3	9.8e-09
HIPK2	GOBP_Pml_Body_Organization	Human	Intestine	A3	2.1e-14
HIPK2	GOBP_Positive_Regulation_Of_Binding	Human	Intestine	A3	1.3e-09
HIPK2	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	3.5e-07
HIPK2	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
HIPK2	GOBP_Positive_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Intestine	A3	6.7e-18
HIPK2	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	2.6e-10
HIPK2	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
HIPK2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
HIPK2	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
HIPK2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	7.8e-15
HIPK2	GOBP_Positive_Regulation_Of_Protein_Binding	Human	Intestine	A3	6.1e-07
HIPK2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
HIPK2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	9.1e-12
HIPK2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	2.0e-08
HIPK2	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
HIPK2	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
HIPK2	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
HIPK2	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
HIPK2	GOBP_Regionalization	Human	Intestine	A3	1.1e-10
HIPK2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	A3	4.8e-12
HIPK2	GOBP_Regulation_Of_Binding	Human	Intestine	A3	4.9e-11
HIPK2	GOBP_Regulation_Of_Catabolic_Process	Human	Intestine	A3	3.5e-16
HIPK2	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
HIPK2	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
HIPK2	GOBP_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	7.2e-15
HIPK2	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Intestine	A3	4.5e-10
HIPK2	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Intestine	A3	7.7e-17
HIPK2	GOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_Stimulus	Human	Intestine	A3	8.9e-16
HIPK2	GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Intestine	A3	3.1e-19
HIPK2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	7.5e-12
HIPK2	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
HIPK2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	1.5e-11
HIPK2	GOBP_Regulation_Of_Protein_Binding	Human	Intestine	A3	4.4e-10
HIPK2	GOBP_Regulation_Of_Protein_Catabolic_Process	Human	Intestine	A3	1.2e-14
HIPK2	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
HIPK2	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	8.8e-11
HIPK2	GOBP_Regulation_Of_Proteolysis	Human	Intestine	A3	9.5e-13
HIPK2	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	A3	1.1e-10
HIPK2	GOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Intestine	A3	2.6e-13
HIPK2	GOBP_Regulation_Of_Ubiquitin_Dependent_Protein_Catabolic_Process	Human	Intestine	A3	6.9e-14
HIPK2	GOBP_Response_To_Abiotic_Stimulus	Human	Intestine	A3	5.3e-18
HIPK2	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
HIPK2	GOBP_Response_To_Oxygen_Levels	Human	Intestine	A3	7.3e-15
HIPK2	GOBP_Retina_Development_In_Camera_Type_Eye	Human	Intestine	A3	1.1e-07
HIPK2	GOBP_Sensory_Organ_Development	Human	Intestine	A3	1.3e-12
HIPK2	GOBP_Sensory_Organ_Morphogenesis	Human	Intestine	A3	4.0e-07
HIPK2	GOBP_Sensory_System_Development	Human	Intestine	A3	8.7e-09
HIPK2	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Intestine	A3	1.7e-07
HIPK2	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
HIPK2	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
HIPK2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	A8	3.3e-08
HIPK2	GOBP_Developmental_Induction	Human	Intestine	A8	2.9e-07
HIPK2	GOBP_Dna_Damage_Response_Signal_Transduction_By_P53_Class_Mediator	Human	Intestine	A8	2.8e-10
HIPK2	GOBP_Dna_Damage_Response_Signal_Transduction_Resulting_In_Transcription	Human	Intestine	A8	4.6e-10
HIPK2	GOBP_Embryonic_Camera_Type_Eye_Development	Human	Intestine	A8	5.2e-09
HIPK2	GOBP_Embryonic_Camera_Type_Eye_Morphogenesis	Human	Intestine	A8	6.0e-11
HIPK2	GOBP_Embryonic_Eye_Morphogenesis	Human	Intestine	A8	8.6e-12
HIPK2	GOBP_Iris_Morphogenesis	Human	Intestine	A8	6.2e-21
HIPK2	GOBP_Lens_Morphogenesis_In_Camera_Type_Eye	Human	Intestine	A8	9.5e-16
HIPK2	GOBP_Myeloid_Cell_Differentiation	Human	Intestine	A8	1.2e-21
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Intestine	A8	1.5e-10
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis	Human	Intestine	A8	8.9e-12
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis_Involved_In_Cellular_Protein_Catabolic_Process	Human	Intestine	A8	7.2e-07
HIPK2	GOBP_Peptidyl_Threonine_Modification	Human	Intestine	A8	1.2e-08
HIPK2	GOBP_Peptidyl_Tyrosine_Modification	Human	Intestine	A8	2.2e-17
HIPK2	GOBP_Positive_Regulation_Of_Dna_Binding	Human	Intestine	A8	4.6e-20
HIPK2	GOBP_Positive_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Intestine	A8	2.1e-08
HIPK2	GOBP_Regulation_Of_Dna_Binding	Human	Intestine	A8	2.2e-12
HIPK2	GOBP_Regulation_Of_Jnk_Cascade	Human	Intestine	A8	2.0e-08
HIPK2	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Intestine	A8	4.3e-23
HIPK2	GOBP_Response_To_Bmp	Human	Intestine	A8	1.0e-10
HIPK2	GOBP_Response_To_Transforming_Growth_Factor_Beta	Human	Intestine	A8	1.1e-10
HIPK2	GOBP_Retina_Morphogenesis_In_Camera_Type_Eye	Human	Intestine	A8	2.1e-18
HIPK2	GOBP_Smad_Protein_Signal_Transduction	Human	Intestine	A8	1.9e-49
HIPK2	GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Intestine	A8	5.8e-13
HIPK2	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
HIPK2	GOBP_Walking_Behavior	Human	Intestine	A8	1.1e-07
HIPK2	GOBP_Camera_Type_Eye_Development	Human	Pancreas	PDAC-B-st1	5.7e-05
HIPK2	GOBP_Eye_Morphogenesis	Human	Pancreas	PDAC-B-st1	5.1e-05
HIPK2	GOBP_Negative_Regulation_Of_Signaling	Human	Pancreas	PDAC-B-st1	1.7e-05
HIPK2	GOBP_Positive_Regulation_Of_Jnk_Cascade	Human	Pancreas	PDAC-B-st1	3.6e-06
HIPK2	GOBP_Positive_Regulation_Of_Mapk_Cascade	Human	Pancreas	PDAC-B-st1	1.1e-05
HIPK2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Pancreas	PDAC-B-st1	8.9e-05
HIPK2	GOBP_Positive_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Pancreas	PDAC-B-st1	4.7e-05
HIPK2	GOBP_Positive_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Pancreas	PDAC-B-st1	9.6e-05
HIPK2	GOBP_Regulation_Of_Jnk_Cascade	Human	Pancreas	PDAC-B-st1	4.6e-05
HIPK2	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Pancreas	PDAC-B-st1	1.6e-06
HIPK2	GOBP_Sensory_Organ_Morphogenesis	Human	Pancreas	PDAC-B-st1	9.8e-06
HIPK2	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Pancreas	PDAC-B-st1	3.7e-05
HIPK2	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Pancreas	PDAC-B-st1	1.5e-05
HIPK2	GOBP_Lens_Morphogenesis_In_Camera_Type_Eye	Human	Pancreas	PDAC-A-st2	1.7e-05
HIPK2	GOBP_Pml_Body_Organization	Human	Pancreas	PDAC-A-st2	2.8e-05
HIPK2	GOBP_Voluntary_Musculoskeletal_Movement	Human	Pancreas	PDAC-A-st2	1.2e-05
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway_By_P53_Class_Mediator	Human	Uterus	rep_1	2.6e-06
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway_In_Response_To_Dna_Damage	Human	Uterus	rep_1	5.1e-06
HIPK2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Uterus	rep_1	2.7e-07
HIPK2	GOBP_Peptidyl_Threonine_Modification	Human	Uterus	rep_1	7.0e-07
HIPK2	GOBP_Positive_Regulation_Of_Binding	Human	Uterus	rep_1	6.3e-06
HIPK2	GOBP_Positive_Regulation_Of_Jnk_Cascade	Human	Uterus	rep_1	1.1e-06
HIPK2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Human	Uterus	rep_1	7.4e-06
HIPK2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Human	Uterus	rep_1	3.7e-07
HIPK2	GOBP_Erythrocyte_Homeostasis	Human	Uterus	rep_25	2.8e-08
HIPK2	GOBP_Walking_Behavior	Human	Uterus	rep_25	1.8e-07
HIPK2	GOBP_Adult_Behavior	Human	Uterus	rep_26	9.3e-11
HIPK2	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
HIPK2	GOBP_Camera_Type_Eye_Morphogenesis	Human	Uterus	rep_26	8.4e-11
HIPK2	GOBP_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	8.2e-11
HIPK2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_26	2.4e-07
HIPK2	GOBP_Developmental_Induction	Human	Uterus	rep_26	1.4e-08
HIPK2	GOBP_Embryonic_Camera_Type_Eye_Development	Human	Uterus	rep_26	1.3e-06
HIPK2	GOBP_Eye_Morphogenesis	Human	Uterus	rep_26	3.7e-14
HIPK2	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Uterus	rep_26	1.5e-12
HIPK2	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
HIPK2	GOBP_Immune_System_Development	Human	Uterus	rep_26	1.0e-06
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway_In_Response_To_Dna_Damage_By_P53_Class_Mediator	Human	Uterus	rep_26	2.3e-13
HIPK2	GOBP_Jnk_Cascade	Human	Uterus	rep_26	2.0e-08
HIPK2	GOBP_Lens_Development_In_Camera_Type_Eye	Human	Uterus	rep_26	1.3e-07
HIPK2	GOBP_Lens_Morphogenesis_In_Camera_Type_Eye	Human	Uterus	rep_26	1.7e-17
HIPK2	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
HIPK2	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	1.1e-07
HIPK2	GOBP_Multicellular_Organismal_Movement	Human	Uterus	rep_26	2.8e-07
HIPK2	GOBP_Myeloid_Cell_Homeostasis	Human	Uterus	rep_26	9.4e-15
HIPK2	GOBP_Negative_Regulation_Of_Catabolic_Process	Human	Uterus	rep_26	4.0e-09
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Uterus	rep_26	4.4e-10
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	9.6e-19
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Apoptotic_Process	Human	Uterus	rep_26	6.4e-11
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Death	Human	Uterus	rep_26	3.7e-10
HIPK2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
HIPK2	GOBP_Negative_Regulation_Of_Protein_Catabolic_Process	Human	Uterus	rep_26	1.3e-06
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis_Involved_In_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	7.9e-15
HIPK2	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Uterus	rep_26	6.2e-13
HIPK2	GOBP_Negative_Regulation_Of_Ubiquitin_Dependent_Protein_Catabolic_Process	Human	Uterus	rep_26	2.6e-15
HIPK2	GOBP_Neuron_Apoptotic_Process	Human	Uterus	rep_26	4.5e-12
HIPK2	GOBP_Neuron_Death	Human	Uterus	rep_26	4.0e-13
HIPK2	GOBP_Nucleus_Organization	Human	Uterus	rep_26	1.3e-06
HIPK2	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
HIPK2	GOBP_Pattern_Specification_Process	Human	Uterus	rep_26	3.6e-06
HIPK2	GOBP_Peptidyl_Serine_Modification	Human	Uterus	rep_26	1.9e-07
HIPK2	GOBP_Pml_Body_Organization	Human	Uterus	rep_26	2.2e-10
HIPK2	GOBP_Positive_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Uterus	rep_26	1.5e-06
HIPK2	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
HIPK2	GOBP_Regionalization	Human	Uterus	rep_26	2.0e-06
HIPK2	GOBP_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	2.7e-10
HIPK2	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
HIPK2	GOBP_Regulation_Of_Protein_Catabolic_Process	Human	Uterus	rep_26	7.3e-06
HIPK2	GOBP_Regulation_Of_Proteolysis	Human	Uterus	rep_26	2.1e-07
HIPK2	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Uterus	rep_26	7.8e-06
HIPK2	GOBP_Regulation_Of_Ubiquitin_Dependent_Protein_Catabolic_Process	Human	Uterus	rep_26	1.2e-10
HIPK2	GOBP_Signal_Transduction_In_Response_To_Dna_Damage	Human	Uterus	rep_26	6.1e-08
HIPK2	GOBP_Smad_Protein_Signal_Transduction	Human	Uterus	rep_26	7.9e-06
HIPK2	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Uterus	rep_26	3.2e-09
HIPK2	GOBP_Iris_Morphogenesis	Human	Uterus	rep_27	3.2e-08
HIPK2	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Uterus	rep_29	4.0e-06
HIPK2	GOBP_Myeloid_Cell_Differentiation	Human	Uterus	rep_29	2.6e-10
HIPK2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Uterus	rep_29	1.2e-06
HIPK2	GOBP_Negative_Regulation_Of_Signaling	Human	Uterus	rep_29	5.3e-06
HIPK2	GOBP_Peptidyl_Tyrosine_Modification	Human	Uterus	rep_29	8.2e-10
HIPK2	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
HIPK2	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Uterus	rep_29	5.5e-06
HIPK2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_29	2.8e-06
HIPK2	GOBP_Adult_Behavior	Human	Breast	rep_1	1.3e-05
HIPK2	GOBP_Adult_Locomotory_Behavior	Human	Breast	rep_1	3.0e-05
HIPK2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Breast	rep_1	1.9e-98
HIPK2	GOBP_Animal_Organ_Morphogenesis	Human	Breast	rep_1	5.4e-25
HIPK2	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Breast	rep_1	1.2e-30
HIPK2	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
HIPK2	GOBP_Blood_Vessel_Morphogenesis	Human	Breast	rep_1	1.5e-106
HIPK2	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
HIPK2	GOBP_Embryonic_Eye_Morphogenesis	Human	Breast	rep_1	5.9e-18
HIPK2	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
HIPK2	GOBP_Immune_System_Development	Human	Breast	rep_1	1.0e-31
HIPK2	GOBP_Locomotory_Behavior	Human	Breast	rep_1	3.1e-38
HIPK2	GOBP_Multicellular_Organismal_Movement	Human	Breast	rep_1	9.7e-10
HIPK2	GOBP_Myeloid_Cell_Differentiation	Human	Breast	rep_1	1.6e-14
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Breast	rep_1	1.8e-27
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Apoptotic_Process	Human	Breast	rep_1	1.2e-11
HIPK2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Breast	rep_1	2.4e-07
HIPK2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Breast	rep_1	4.6e-15
HIPK2	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
HIPK2	GOBP_Neuron_Differentiation	Human	Breast	rep_1	1.1e-16
HIPK2	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	9.2e-11
HIPK2	GOBP_Positive_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_Stimulus	Human	Breast	rep_1	7.0e-44
HIPK2	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
HIPK2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
HIPK2	GOBP_Positive_Regulation_Of_Protein_Binding	Human	Breast	rep_1	1.9e-19
HIPK2	GOBP_Positive_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Breast	rep_1	8.9e-19
HIPK2	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Breast	rep_1	4.6e-40
HIPK2	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Breast	rep_1	4.6e-22
HIPK2	GOBP_Regulation_Of_Binding	Human	Breast	rep_1	6.1e-11
HIPK2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Human	Breast	rep_1	2.3e-15
HIPK2	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Breast	rep_1	8.3e-72
HIPK2	GOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_Stimulus	Human	Breast	rep_1	2.1e-15
HIPK2	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
HIPK2	GOBP_Regulation_Of_Protein_Binding	Human	Breast	rep_1	1.6e-99
HIPK2	GOBP_Regulation_Of_Proteolysis	Human	Breast	rep_1	6.4e-05
HIPK2	GOBP_Regulation_Of_Response_To_Stress	Human	Breast	rep_1	3.4e-19
HIPK2	GOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Breast	rep_1	9.9e-11
HIPK2	GOBP_Regulation_Of_Vasculature_Development	Human	Breast	rep_1	1.9e-30
HIPK2	GOBP_Response_To_Abiotic_Stimulus	Human	Breast	rep_1	2.6e-19
HIPK2	GOBP_Response_To_Growth_Factor	Human	Breast	rep_1	1.2e-13
HIPK2	GOBP_Response_To_Oxygen_Levels	Human	Breast	rep_1	6.1e-99
HIPK2	GOBP_Response_To_Transforming_Growth_Factor_Beta	Human	Breast	rep_1	2.4e-65
HIPK2	GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Breast	rep_1	4.6e-27
HIPK2	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
HIPK2	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
HIPK2	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
HIPK2	GOBP_Anterior_Posterior_Pattern_Specification	Human	Breast	rep_5	1.5e-08
HIPK2	GOBP_Behavior	Human	Breast	rep_5	3.9e-08
HIPK2	GOBP_Camera_Type_Eye_Morphogenesis	Human	Breast	rep_5	7.5e-04
HIPK2	GOBP_Cellular_Protein_Catabolic_Process	Human	Breast	rep_5	4.4e-04
HIPK2	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Breast	rep_5	4.9e-11
HIPK2	GOBP_Developmental_Induction	Human	Breast	rep_5	7.8e-07
HIPK2	GOBP_Embryo_Development	Human	Breast	rep_5	5.5e-08
HIPK2	GOBP_Embryonic_Morphogenesis	Human	Breast	rep_5	2.0e-06
HIPK2	GOBP_Embryonic_Organ_Development	Human	Breast	rep_5	3.3e-05
HIPK2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Breast	rep_5	4.6e-14
HIPK2	GOBP_Eye_Morphogenesis	Human	Breast	rep_5	1.7e-06
HIPK2	GOBP_Jnk_Cascade	Human	Breast	rep_5	4.2e-05
HIPK2	GOBP_Mapk_Cascade	Human	Breast	rep_5	4.6e-17
HIPK2	GOBP_Negative_Regulation_Of_Cell_Death	Human	Breast	rep_5	1.9e-07
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Death	Human	Breast	rep_5	9.9e-10
HIPK2	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	4.3e-05
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis	Human	Breast	rep_5	2.0e-06
HIPK2	GOBP_Negative_Regulation_Of_Signaling	Human	Breast	rep_5	8.6e-14
HIPK2	GOBP_Neuron_Death	Human	Breast	rep_5	6.5e-07
HIPK2	GOBP_Pattern_Specification_Process	Human	Breast	rep_5	3.7e-14
HIPK2	GOBP_Peptidyl_Serine_Modification	Human	Breast	rep_5	1.3e-04
HIPK2	GOBP_Peptidyl_Tyrosine_Modification	Human	Breast	rep_5	3.3e-18
HIPK2	GOBP_Positive_Regulation_Of_Binding	Human	Breast	rep_5	2.1e-11
HIPK2	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	5.3e-08
HIPK2	GOBP_Positive_Regulation_Of_Jnk_Cascade	Human	Breast	rep_5	4.6e-11
HIPK2	GOBP_Positive_Regulation_Of_Mapk_Cascade	Human	Breast	rep_5	1.9e-16
HIPK2	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
HIPK2	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
HIPK2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	5.9e-12
HIPK2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
HIPK2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	3.0e-10
HIPK2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	1.0e-15
HIPK2	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
HIPK2	GOBP_Positive_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Breast	rep_5	3.2e-11
HIPK2	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
HIPK2	GOBP_Regionalization	Human	Breast	rep_5	5.8e-16
HIPK2	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
HIPK2	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
HIPK2	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Breast	rep_5	8.1e-10
HIPK2	GOBP_Regulation_Of_Dna_Binding	Human	Breast	rep_5	3.3e-09
HIPK2	GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Breast	rep_5	8.2e-07
HIPK2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	8.7e-11
HIPK2	GOBP_Regulation_Of_Jnk_Cascade	Human	Breast	rep_5	5.1e-06
HIPK2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	2.5e-06
HIPK2	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
HIPK2	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	5.8e-14
HIPK2	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Breast	rep_5	9.2e-08
HIPK2	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
HIPK2	GOBP_Retina_Morphogenesis_In_Camera_Type_Eye	Human	Breast	rep_5	1.1e-06
HIPK2	GOBP_Sensory_Organ_Morphogenesis	Human	Breast	rep_5	1.7e-05
HIPK2	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Breast	rep_5	1.3e-07
HIPK2	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Breast	rep_5	4.5e-06
HIPK2	GOBP_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	4.8e-09
HIPK2	GOBP_Camera_Type_Eye_Development	Human	Breast	rep_6	9.2e-06
HIPK2	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
HIPK2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	6.0e-06
HIPK2	GOBP_Embryonic_Camera_Type_Eye_Development	Human	Breast	rep_6	5.8e-08
HIPK2	GOBP_Embryonic_Organ_Morphogenesis	Human	Breast	rep_6	1.8e-08
HIPK2	GOBP_Embryonic_Retina_Morphogenesis_In_Camera_Type_Eye	Human	Breast	rep_6	1.0e-06
HIPK2	GOBP_Erythrocyte_Homeostasis	Human	Breast	rep_6	3.6e-05
HIPK2	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Breast	rep_6	5.1e-04
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	2.7e-08
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway_By_P53_Class_Mediator	Human	Breast	rep_6	2.9e-05
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway_In_Response_To_Dna_Damage	Human	Breast	rep_6	9.9e-04
HIPK2	GOBP_Iris_Morphogenesis	Human	Breast	rep_6	1.4e-04
HIPK2	GOBP_Lens_Morphogenesis_In_Camera_Type_Eye	Human	Breast	rep_6	1.8e-08
HIPK2	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
HIPK2	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Human	Breast	rep_6	2.2e-09
HIPK2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Breast	rep_6	2.6e-08
HIPK2	GOBP_Negative_Regulation_Of_Catabolic_Process	Human	Breast	rep_6	2.0e-06
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Breast	rep_6	1.0e-06
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Breast	rep_6	4.8e-10
HIPK2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
HIPK2	GOBP_Negative_Regulation_Of_Protein_Catabolic_Process	Human	Breast	rep_6	1.3e-04
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis_Involved_In_Cellular_Protein_Catabolic_Process	Human	Breast	rep_6	4.0e-10
HIPK2	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	8.2e-08
HIPK2	GOBP_Negative_Regulation_Of_Ubiquitin_Dependent_Protein_Catabolic_Process	Human	Breast	rep_6	6.2e-09
HIPK2	GOBP_Neuron_Apoptotic_Process	Human	Breast	rep_6	1.3e-06
HIPK2	GOBP_Nucleus_Organization	Human	Breast	rep_6	8.5e-06
HIPK2	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
HIPK2	GOBP_Peptidyl_Amino_Acid_Modification	Human	Breast	rep_6	3.8e-05
HIPK2	GOBP_Positive_Regulation_Of_Dna_Binding	Human	Breast	rep_6	2.3e-04
HIPK2	GOBP_Positive_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Breast	rep_6	2.6e-04
HIPK2	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
HIPK2	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
HIPK2	GOBP_Regulation_Of_Catabolic_Process	Human	Breast	rep_6	3.3e-04
HIPK2	GOBP_Regulation_Of_Cellular_Protein_Catabolic_Process	Human	Breast	rep_6	6.2e-07
HIPK2	GOBP_Regulation_Of_Protein_Catabolic_Process	Human	Breast	rep_6	4.3e-04
HIPK2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Human	Breast	rep_6	1.6e-04
HIPK2	GOBP_Regulation_Of_Ubiquitin_Dependent_Protein_Catabolic_Process	Human	Breast	rep_6	5.9e-07
HIPK2	GOBP_Sensory_Organ_Development	Human	Breast	rep_6	1.3e-09
HIPK2	GOBP_Sensory_System_Development	Human	Breast	rep_6	8.2e-06
HIPK2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Human	Breast	rep_6	7.7e-05
HIPK2	GOBP_Signal_Transduction_In_Response_To_Dna_Damage	Human	Breast	rep_6	1.7e-07
HIPK2	GOBP_Smoothened_Signaling_Pathway	Human	Breast	rep_6	1.8e-04
HIPK2	GOBP_Walking_Behavior	Human	Breast	rep_6	4.3e-15
HIPK2	GOBP_Lens_Morphogenesis_In_Camera_Type_Eye	Human	Skin	P5_rep1	7.3e-08
HIPK2	GOBP_Embryonic_Camera_Type_Eye_Development	Human	Skin	P5_rep3	6.9e-23
HIPK2	GOBP_Embryonic_Retina_Morphogenesis_In_Camera_Type_Eye	Human	Skin	P5_rep3	1.5e-12
HIPK2	GOBP_Peptidyl_Threonine_Modification	Human	Skin	P5_rep3	1.4e-09
HIPK2	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Skin	P9_rep2	2.5e-08
HIPK2	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
HIPK2	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Skin	P9_rep3	4.3e-09
HIPK2	GOBP_Nuclear_Body_Organization	Human	Skin	P10_rep1	5.6e-09
HIPK2	GOBP_Pml_Body_Organization	Human	Skin	P10_rep1	3.8e-08
HIPK2	GOBP_Walking_Behavior	Human	Skin	P10_rep1	6.2e-12
HIPK2	GOBP_Embryonic_Camera_Type_Eye_Morphogenesis	Human	Skin	P10_rep2	4.3e-22
HIPK2	GOBP_Embryonic_Eye_Morphogenesis	Human	Skin	P10_rep2	7.3e-08
HIPK2	GOBP_Iris_Morphogenesis	Human	Skin	P10_rep2	7.7e-14
HIPK2	GOBP_Multicellular_Organismal_Movement	Human	Skin	P10_rep2	2.4e-09
HIPK2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Human	Skin	P10_rep2	7.3e-12
HIPK2	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
HIPK2	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Lung	rep_1	2.8e-10
HIPK2	GOBP_Myeloid_Cell_Differentiation	Human	Lung	rep_1	8.1e-08
HIPK2	GOBP_Negative_Regulation_Of_Proteolysis	Human	Lung	rep_1	5.7e-10
HIPK2	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Lung	rep_1	7.3e-07
HIPK2	GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Lung	rep_1	1.9e-10
HIPK2	GOBP_Regulation_Of_Proteolysis	Human	Lung	rep_1	3.2e-08
HIPK2	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Lung	rep_2	4.5e-08
HIPK2	GOBP_Immune_System_Development	Human	Lung	rep_2	7.9e-07
HIPK2	GOBP_Negative_Regulation_Of_Cellular_Catabolic_Process	Human	Lung	rep_2	3.4e-07
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Apoptotic_Process	Human	Lung	rep_2	7.1e-08
HIPK2	GOBP_Negative_Regulation_Of_Neuron_Death	Human	Lung	rep_2	8.1e-08
HIPK2	GOBP_Neuron_Apoptotic_Process	Human	Lung	rep_2	7.1e-08
HIPK2	GOBP_Neuron_Death	Human	Lung	rep_2	3.5e-08
HIPK2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Human	Lung	rep_2	1.4e-07
HIPK2	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07

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HIPK2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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HIPK2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for HIPK2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for HIPK2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
HIPK2	Q9H2X6	DB12010	Fostamatinib	Homeodomain-interacting protein kinase 2	SmallMoleculeDrug	approved\|investigational

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Related Diseases for HIPK2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
HIPK2	C0027719	Nephrosclerosis	1	CTD_human
HIPK2	C0041956	Ureteral obstruction	1	CTD_human
HIPK2	C0238198	Gastrointestinal Stromal Tumors	1	CTD_human
HIPK2	C3179349	Gastrointestinal Stromal Sarcoma	1	CTD_human