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Spatial pattern gene: NTMT1 (spascer ID:28989) |
Gene summary for NTMT1 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | NTMT1 | Gene ID | 28989 |
| Gene name | N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
| Synonyms | AD-003|C9orf32|HOMT1A|METTL11A|NRMT|NRMT1|NTM1A |
| Cytomap | 9q34.11 |
| Type of gene | protein-coding |
| Description | N-terminal Xaa-Pro-Lys N-methyltransferase 1N-terminal RCC1 methyltransferaseX-Pro-Lys N-terminal protein methyltransferase 1Aalpha N-terminal protein methyltransferase 1Amethyltransferase-like protein 11A |
| Modification date | 20220513 |
| UniProtAcc | Q9BV86 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| NTMT1 | GO:0005737 | cytoplasm | 21873635 | Component |
| NTMT1 | GO:0006480 | N-terminal protein amino acid methylation | 21873635 | Process |
| NTMT1 | GO:0008168 | methyltransferase activity | 21873635 | Function |
| NTMT1 | GO:0018011 | N-terminal peptidyl-alanine methylation | 21873635 | Process |
| NTMT1 | GO:0035568 | N-terminal peptidyl-proline methylation | 21873635 | Process |
| NTMT1 | GO:0035570 | N-terminal peptidyl-serine methylation | 21873635 | Process |
| NTMT1 | GO:0071885 | N-terminal protein N-methyltransferase activity | 21873635 | Function |
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Spatial pattern events for NTMT1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| NTMT1 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| NTMT1 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| NTMT1 | Human | Liver | rep_liver2 | 34417225 | 1.23e-07 |
| NTMT1 | Human | Intestine | A4 | 33406409 | 7.21e-06 |
| NTMT1 | Human | Uterus | rep_2 | 34857954 | 2.38e-09 |
| NTMT1 | Human | Uterus | rep_3 | 34857954 | 2.11e-12 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Intestine_A4_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
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Spatial pattern pathway has NTMT1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| NTMT1 | GOBP_Cell_Cycle | Human | Intestine | A3 | 2.7e-11 |
| NTMT1 | GOBP_Cell_Cycle_Process | Human | Intestine | A3 | 2.7e-14 |
| NTMT1 | GOBP_Chromatin_Organization | Human | Intestine | A3 | 3.2e-11 |
| NTMT1 | GOBP_Chromosome_Organization | Human | Intestine | A3 | 2.5e-13 |
| NTMT1 | GOBP_Chromosome_Segregation | Human | Intestine | A3 | 4.7e-12 |
| NTMT1 | GOBP_Histone_Methylation | Human | Intestine | A3 | 5.5e-08 |
| NTMT1 | GOBP_Methylation | Human | Intestine | A3 | 5.9e-09 |
| NTMT1 | GOBP_Microtubule_Based_Process | Human | Intestine | A3 | 3.4e-11 |
| NTMT1 | GOBP_Microtubule_Cytoskeleton_Organization | Human | Intestine | A3 | 4.8e-11 |
| NTMT1 | GOBP_Peptidyl_Amino_Acid_Modification | Human | Intestine | A3 | 2.7e-09 |
| NTMT1 | GOBP_Peptidyl_Proline_Modification | Human | Intestine | A3 | 1.2e-12 |
| NTMT1 | GOBP_Peptidyl_Serine_Modification | Human | Intestine | A3 | 9.8e-09 |
| NTMT1 | GOBP_Protein_Methylation | Human | Intestine | A3 | 7.4e-07 |
| NTMT1 | GOBP_Spindle_Organization | Human | Intestine | A3 | 4.4e-08 |
| NTMT1 | GOBP_Chromosome_Segregation | Human | Pancreas | PDAC-B-st1 | 3.3e-05 |
| NTMT1 | GOBP_Spindle_Organization | Human | Pancreas | PDAC-B-st1 | 3.4e-05 |
| NTMT1 | GOBP_Chromatin_Organization | Human | Uterus | rep_1 | 1.9e-06 |
| NTMT1 | GOBP_Chromosome_Organization | Human | Uterus | rep_26 | 1.2e-09 |
| NTMT1 | GOBP_Chromosome_Segregation | Human | Uterus | rep_26 | 5.6e-19 |
| NTMT1 | GOBP_Histone_Methylation | Human | Uterus | rep_26 | 5.5e-11 |
| NTMT1 | GOBP_Methylation | Human | Uterus | rep_26 | 1.9e-06 |
| NTMT1 | GOBP_Peptidyl_Serine_Modification | Human | Uterus | rep_26 | 1.9e-07 |
| NTMT1 | GOBP_Protein_Methylation | Human | Uterus | rep_26 | 1.8e-11 |
| NTMT1 | GOBP_Spindle_Organization | Human | Uterus | rep_26 | 3.2e-06 |
| NTMT1 | GOBP_Cytoskeleton_Organization | Human | Breast | rep_1 | 1.3e-22 |
| NTMT1 | GOBP_Peptidyl_Proline_Modification | Human | Breast | rep_5 | 9.7e-05 |
| NTMT1 | GOBP_Peptidyl_Serine_Modification | Human | Breast | rep_5 | 1.3e-04 |
| NTMT1 | GOBP_Cell_Cycle | Human | Breast | rep_6 | 3.4e-09 |
| NTMT1 | GOBP_Cell_Cycle_Process | Human | Breast | rep_6 | 6.7e-09 |
| NTMT1 | GOBP_Chromatin_Organization | Human | Breast | rep_6 | 4.3e-07 |
| NTMT1 | GOBP_Chromosome_Organization | Human | Breast | rep_6 | 1.1e-06 |
| NTMT1 | GOBP_Chromosome_Segregation | Human | Breast | rep_6 | 1.9e-05 |
| NTMT1 | GOBP_Methylation | Human | Breast | rep_6 | 1.7e-06 |
| NTMT1 | GOBP_Microtubule_Based_Process | Human | Breast | rep_6 | 1.8e-04 |
| NTMT1 | GOBP_Microtubule_Cytoskeleton_Organization | Human | Breast | rep_6 | 1.9e-04 |
| NTMT1 | GOBP_N_Terminal_Protein_Amino_Acid_Modification | Human | Breast | rep_6 | 2.9e-09 |
| NTMT1 | GOBP_Peptidyl_Amino_Acid_Modification | Human | Breast | rep_6 | 3.8e-05 |
| NTMT1 | GOBP_Spindle_Organization | Human | Breast | rep_6 | 2.9e-05 |
| NTMT1 | GOBP_Cytoskeleton_Organization | Human | Skin | P9_rep3 | 3.1e-12 |
| NTMT1 | GOBP_N_Terminal_Protein_Amino_Acid_Modification | Human | Skin | P10_rep1 | 3.5e-11 |
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NTMT1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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NTMT1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for NTMT1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for NTMT1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for NTMT1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
