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Spatial pattern gene: NOB1 (spascer ID:28987) |
Gene summary for NOB1 |
Gene summary |
| Gene information | |
| Species | Human | Gene symbol | NOB1 | Gene ID | 28987 |
| Gene name | NIN1 (RPN12) binding protein 1 homolog |
| Synonyms | ART-4|MST158|MSTP158|NOB1P|PSMD8BP1 |
| Cytomap | 16q22.1 |
| Type of gene | protein-coding |
| Description | RNA-binding protein NOB1NIN1/PSMD8 binding protein 1 homologPSMD8 binding protein 1adenocarcinoma antigen recognized by T lymphocytes 4nin one binding proteinphosphorylation regulatory protein HP-10protein ART-4 |
| Modification date | 20220513 |
| UniProtAcc | Q9ULX3 |
Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| NOB1 | GO:0004521 | endoribonuclease activity | 21873635 | Function |
| NOB1 | GO:0030490 | maturation of SSU-rRNA | 21873635 | Process |
| NOB1 | GO:0030688 | preribosome, small subunit precursor | 21873635 | Component |
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Spatial pattern events for NOB1 |
spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| NOB1 | Human | Intestine | rep_colon1 | 34417225 | 2.22e-12 |
| NOB1 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| NOB1 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| NOB1 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| NOB1 | Human | Intestine | A2 | 33406409 | 7.08e-06 |
| NOB1 | Human | Uterus | rep_2 | 34857954 | 4.21e-07 |
| NOB1 | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E ![]() | ![]() |
Intestine_rep_colon4_H&E ![]() | ![]() |
Liver_rep_liver1_H&E ![]() | ![]() |
Liver_rep_liver2_H&E ![]() | ![]() |
Intestine_A2_H&E ![]() | ![]() |
Uterus_rep_2_H&E ![]() | ![]() |
Uterus_rep_3_H&E ![]() | ![]() |
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Spatial pattern pathway has NOB1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| NOB1 | GOBP_Sensory_Perception_Of_Light_Stimulus | Human | Bladder | rep_2 | 3.7e-17 |
| NOB1 | GOBP_Maturation_Of_Ssu_Rrna | Human | Intestine | A1 | 1.5e-17 |
| NOB1 | GOBP_Ribosomal_Small_Subunit_Biogenesis | Human | Intestine | A1 | 3.0e-16 |
| NOB1 | GOBP_Ribosome_Biogenesis | Human | Intestine | A1 | 6.5e-08 |
| NOB1 | GOBP_Ncrna_Metabolic_Process | Human | Intestine | A3 | 8.6e-07 |
| NOB1 | GOBP_Nervous_System_Process | Human | Intestine | A3 | 9.7e-07 |
| NOB1 | GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis | Human | Intestine | A3 | 1.9e-08 |
| NOB1 | GOBP_Rna_Phosphodiester_Bond_Hydrolysis | Human | Intestine | A3 | 2.3e-07 |
| NOB1 | GOBP_Rna_Processing | Human | Intestine | A3 | 3.9e-09 |
| NOB1 | GOBP_Sensory_Perception | Human | Intestine | A8 | 2.1e-09 |
| NOB1 | GOBP_Rna_Phosphodiester_Bond_Hydrolysis | Human | Pancreas | PDAC-B-st1 | 3.3e-05 |
| NOB1 | GOBP_Ncrna_Processing | Human | Uterus | rep_1 | 4.5e-06 |
| NOB1 | GOBP_Ribosomal_Small_Subunit_Biogenesis | Human | Uterus | rep_1 | 3.0e-06 |
| NOB1 | GOBP_Ribosome_Biogenesis | Human | Uterus | rep_1 | 9.5e-06 |
| NOB1 | GOBP_Rrna_Metabolic_Process | Human | Uterus | rep_1 | 2.4e-07 |
| NOB1 | GOBP_Maturation_Of_Ssu_Rrna | Human | Uterus | rep_26 | 1.3e-06 |
| NOB1 | GOBP_Nervous_System_Process | Human | Uterus | rep_26 | 2.3e-07 |
| NOB1 | GOBP_Rna_Phosphodiester_Bond_Hydrolysis_Endonucleolytic | Human | Uterus | rep_26 | 3.6e-07 |
| NOB1 | GOBP_Nervous_System_Process | Human | Breast | rep_1 | 1.2e-04 |
| NOB1 | GOBP_Sensory_Perception_Of_Light_Stimulus | Human | Breast | rep_1 | 8.2e-37 |
| NOB1 | GOBP_Cleavage_Involved_In_Rrna_Processing | Human | Breast | rep_6 | 3.4e-05 |
| NOB1 | GOBP_Maturation_Of_Ssu_Rrna | Human | Breast | rep_6 | 6.4e-06 |
| NOB1 | GOBP_Ncrna_Metabolic_Process | Human | Breast | rep_6 | 1.9e-04 |
| NOB1 | GOBP_Ncrna_Processing | Human | Breast | rep_6 | 1.3e-05 |
| NOB1 | GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis | Human | Breast | rep_6 | 2.6e-05 |
| NOB1 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Human | Breast | rep_6 | 1.3e-07 |
| NOB1 | GOBP_Ribosomal_Small_Subunit_Biogenesis | Human | Breast | rep_6 | 2.8e-07 |
| NOB1 | GOBP_Ribosome_Biogenesis | Human | Breast | rep_6 | 2.0e-06 |
| NOB1 | GOBP_Rna_Phosphodiester_Bond_Hydrolysis | Human | Breast | rep_6 | 2.8e-06 |
| NOB1 | GOBP_Rna_Phosphodiester_Bond_Hydrolysis_Endonucleolytic | Human | Breast | rep_6 | 3.0e-08 |
| NOB1 | GOBP_Rna_Processing | Human | Breast | rep_6 | 3.5e-06 |
| NOB1 | GOBP_Rrna_Metabolic_Process | Human | Breast | rep_6 | 4.0e-06 |
| NOB1 | GOBP_Cleavage_Involved_In_Rrna_Processing | Human | Skin | P10_rep2 | 1.9e-08 |
| NOB1 | GOBP_Rna_Phosphodiester_Bond_Hydrolysis | Human | Lung | rep_1 | 8.8e-08 |
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NOB1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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NOB1 function as liang/receptor across spatial transcriptomics tissue |
Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for NOB1 envolved |
Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
Motif information. |
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Related Drugs for NOB1 |
Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for NOB1 |
Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |