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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: NOB1 (spascer ID:28987)

Gene summary for NOB1

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

NOB1

Gene ID

28987

Gene nameNIN1 (RPN12) binding protein 1 homolog
SynonymsART-4|MST158|MSTP158|NOB1P|PSMD8BP1
Cytomap16q22.1
Type of geneprotein-coding
DescriptionRNA-binding protein NOB1NIN1/PSMD8 binding protein 1 homologPSMD8 binding protein 1adenocarcinoma antigen recognized by T lymphocytes 4nin one binding proteinphosphorylation regulatory protein HP-10protein ART-4
Modification date20220513
UniProtAcc

Q9ULX3


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
NOB1

GO:0004521

endoribonuclease activity

21873635

Function
NOB1

GO:0030490

maturation of SSU-rRNA

21873635

Process
NOB1

GO:0030688

preribosome, small subunit precursor

21873635

Component

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Spatial pattern events for NOB1

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
NOB1HumanIntestinerep_colon1 344172252.22e-12
NOB1HumanIntestinerep_colon4 344172251.14e-15
NOB1HumanLiverrep_liver1 344172251.08e-15
NOB1HumanLiverrep_liver2 344172256.98e-16
NOB1HumanIntestineA2 334064097.08e-06
NOB1HumanUterusrep_2 348579544.21e-07
NOB1HumanUterusrep_3 348579541.66e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon1_H&E
boxplot

boxplot
Intestine_rep_colon4_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Intestine_A2_H&E
boxplot

boxplot
Uterus_rep_2_H&E
boxplot

boxplot
Uterus_rep_3_H&E
boxplot

boxplot


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Spatial pattern pathway has NOB1 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
NOB1GOBP_Sensory_Perception_Of_Light_StimulusHumanBladderrep_2 3.7e-17
NOB1GOBP_Maturation_Of_Ssu_RrnaHumanIntestineA1 1.5e-17
NOB1GOBP_Ribosomal_Small_Subunit_BiogenesisHumanIntestineA1 3.0e-16
NOB1GOBP_Ribosome_BiogenesisHumanIntestineA1 6.5e-08
NOB1GOBP_Ncrna_Metabolic_ProcessHumanIntestineA3 8.6e-07
NOB1GOBP_Nervous_System_ProcessHumanIntestineA3 9.7e-07
NOB1GOBP_Nucleic_Acid_Phosphodiester_Bond_HydrolysisHumanIntestineA3 1.9e-08
NOB1GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanIntestineA3 2.3e-07
NOB1GOBP_Rna_ProcessingHumanIntestineA3 3.9e-09
NOB1GOBP_Sensory_PerceptionHumanIntestineA8 2.1e-09
NOB1GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanPancreasPDAC-B-st1 3.3e-05
NOB1GOBP_Ncrna_ProcessingHumanUterusrep_1 4.5e-06
NOB1GOBP_Ribosomal_Small_Subunit_BiogenesisHumanUterusrep_1 3.0e-06
NOB1GOBP_Ribosome_BiogenesisHumanUterusrep_1 9.5e-06
NOB1GOBP_Rrna_Metabolic_ProcessHumanUterusrep_1 2.4e-07
NOB1GOBP_Maturation_Of_Ssu_RrnaHumanUterusrep_26 1.3e-06
NOB1GOBP_Nervous_System_ProcessHumanUterusrep_26 2.3e-07
NOB1GOBP_Rna_Phosphodiester_Bond_Hydrolysis_EndonucleolyticHumanUterusrep_26 3.6e-07
NOB1GOBP_Nervous_System_ProcessHumanBreastrep_1 1.2e-04
NOB1GOBP_Sensory_Perception_Of_Light_StimulusHumanBreastrep_1 8.2e-37
NOB1GOBP_Cleavage_Involved_In_Rrna_ProcessingHumanBreastrep_6 3.4e-05
NOB1GOBP_Maturation_Of_Ssu_RrnaHumanBreastrep_6 6.4e-06
NOB1GOBP_Ncrna_Metabolic_ProcessHumanBreastrep_6 1.9e-04
NOB1GOBP_Ncrna_ProcessingHumanBreastrep_6 1.3e-05
NOB1GOBP_Nucleic_Acid_Phosphodiester_Bond_HydrolysisHumanBreastrep_6 2.6e-05
NOB1GOBP_Ribonucleoprotein_Complex_BiogenesisHumanBreastrep_6 1.3e-07
NOB1GOBP_Ribosomal_Small_Subunit_BiogenesisHumanBreastrep_6 2.8e-07
NOB1GOBP_Ribosome_BiogenesisHumanBreastrep_6 2.0e-06
NOB1GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanBreastrep_6 2.8e-06
NOB1GOBP_Rna_Phosphodiester_Bond_Hydrolysis_EndonucleolyticHumanBreastrep_6 3.0e-08
NOB1GOBP_Rna_ProcessingHumanBreastrep_6 3.5e-06
NOB1GOBP_Rrna_Metabolic_ProcessHumanBreastrep_6 4.0e-06
NOB1GOBP_Cleavage_Involved_In_Rrna_ProcessingHumanSkinP10_rep2 1.9e-08
NOB1GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanLungrep_1 8.8e-08

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NOB1 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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NOB1 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for NOB1 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for NOB1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NOB1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource