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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: FLVCR1 (spascer ID:28982)

Gene summary for FLVCR1

Gene summary

Gene information
	Species	Human
	Gene symbol	FLVCR1
	Gene ID	28982
	Gene name	FLVCR heme transporter 1
	Synonyms	AXPC1\|FLVCR\|MFSD7B\|PCA\|PCARP\|SLC49A1
	Cytomap	1q32.3
	Type of gene	protein-coding
	Description	feline leukemia virus subgroup C receptor-related protein 1feline leukemia virus subgroup C cellular receptor 1
	Modification date	20220513
	UniProtAcc	Q9Y5Y0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
FLVCR1	GO:0005739	mitochondrion	21873635	Component
FLVCR1	GO:0006839	mitochondrial transport	21873635	Process
FLVCR1	GO:0015232	heme transmembrane transporter activity	21873635	Function
FLVCR1	GO:0020037	heme binding	21873635	Function
FLVCR1	GO:0030218	erythrocyte differentiation	21873635	Process
FLVCR1	GO:0097037	heme export	21873635	Process

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Spatial pattern events for FLVCR1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
FLVCR1	Human	Liver	rep_liver1	34417225	1.08e-15
FLVCR1	Human	Liver	rep_liver2	34417225	6.98e-16
FLVCR1	Human	Breast	1160920F	34493872	1.28e-06
FLVCR1	Human	Breast	CID44971	34493872	1.66e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has FLVCR1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
FLVCR1	GOBP_Transmembrane_Transport	Human	Brain	rep_1	2.8e-23
FLVCR1	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
FLVCR1	GOBP_Growth	Human	Brain	rep_4	1.0e-14
FLVCR1	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
FLVCR1	GOBP_Appendage_Morphogenesis	Human	Bladder	rep_2	2.1e-04
FLVCR1	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
FLVCR1	GOBP_Skeletal_System_Development	Human	Bladder	rep_2	2.5e-15
FLVCR1	GOBP_Skeletal_System_Morphogenesis	Human	Bladder	rep_2	7.5e-11
FLVCR1	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
FLVCR1	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
FLVCR1	GOBP_Growth	Human	Liver	rep_1	2.1e-52
FLVCR1	GOBP_Transmembrane_Transport	Human	Liver	rep_1	1.0e-70
FLVCR1	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
FLVCR1	GOBP_Growth	Human	Intestine	rep_colon2	1.5e-57
FLVCR1	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
FLVCR1	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
FLVCR1	GOBP_Cation_Transport	Human	Intestine	A3	1.3e-09
FLVCR1	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
FLVCR1	GOBP_Developmental_Growth	Human	Intestine	A3	7.3e-10
FLVCR1	GOBP_Developmental_Maturation	Human	Intestine	A3	2.5e-14
FLVCR1	GOBP_Embryo_Development	Human	Intestine	A3	2.4e-07
FLVCR1	GOBP_Embryonic_Morphogenesis	Human	Intestine	A3	1.3e-11
FLVCR1	GOBP_Embryonic_Organ_Development	Human	Intestine	A3	1.4e-10
FLVCR1	GOBP_Embryonic_Organ_Morphogenesis	Human	Intestine	A3	1.5e-09
FLVCR1	GOBP_Growth	Human	Intestine	A3	3.3e-16
FLVCR1	GOBP_Head_Development	Human	Intestine	A3	3.8e-09
FLVCR1	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Intestine	A3	7.2e-10
FLVCR1	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
FLVCR1	GOBP_Immune_System_Development	Human	Intestine	A3	4.3e-10
FLVCR1	GOBP_Mitochondrial_Transport	Human	Intestine	A3	9.8e-16
FLVCR1	GOBP_Myeloid_Cell_Homeostasis	Human	Intestine	A3	1.0e-07
FLVCR1	GOBP_Regulation_Of_Developmental_Growth	Human	Intestine	A3	5.3e-18
FLVCR1	GOBP_Regulation_Of_Growth	Human	Intestine	A3	3.6e-10
FLVCR1	GOBP_Regulation_Of_Organ_Growth	Human	Intestine	A3	7.5e-10
FLVCR1	GOBP_Transmembrane_Transport	Human	Intestine	A3	1.4e-10
FLVCR1	GOBP_Anatomical_Structure_Maturation	Human	Intestine	A8	1.0e-12
FLVCR1	GOBP_Body_Morphogenesis	Human	Intestine	A8	6.8e-09
FLVCR1	GOBP_Cell_Maturation	Human	Intestine	A8	2.9e-08
FLVCR1	GOBP_Cellular_Homeostasis	Human	Intestine	A8	2.1e-11
FLVCR1	GOBP_Cellular_Ion_Homeostasis	Human	Intestine	A8	4.3e-12
FLVCR1	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Human	Intestine	A8	1.4e-07
FLVCR1	GOBP_Chemical_Homeostasis	Human	Intestine	A8	1.3e-12
FLVCR1	GOBP_Embryonic_Skeletal_System_Development	Human	Intestine	A8	1.1e-07
FLVCR1	GOBP_Embryonic_Skeletal_System_Morphogenesis	Human	Intestine	A8	5.9e-08
FLVCR1	GOBP_Erythrocyte_Maturation	Human	Intestine	A8	1.4e-15
FLVCR1	GOBP_Head_Morphogenesis	Human	Intestine	A8	6.3e-08
FLVCR1	GOBP_Heme_Transport	Human	Intestine	A8	2.4e-19
FLVCR1	GOBP_Ion_Homeostasis	Human	Intestine	A8	6.1e-15
FLVCR1	GOBP_Iron_Coordination_Entity_Transport	Human	Intestine	A8	1.0e-12
FLVCR1	GOBP_Metal_Ion_Homeostasis	Human	Intestine	A8	2.2e-10
FLVCR1	GOBP_Myeloid_Cell_Development	Human	Intestine	A8	5.8e-08
FLVCR1	GOBP_Myeloid_Cell_Differentiation	Human	Intestine	A8	1.2e-21
FLVCR1	GOBP_Organ_Growth	Human	Intestine	A8	7.7e-11
FLVCR1	GOBP_Spleen_Development	Human	Intestine	A8	5.9e-21
FLVCR1	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
FLVCR1	GOBP_Head_Development	Human	Pancreas	PDAC-B-st1	2.0e-05
FLVCR1	GOBP_Transition_Metal_Ion_Homeostasis	Human	Pancreas	PDAC-B-st1	1.1e-05
FLVCR1	GOBP_Embryonic_Digit_Morphogenesis	Human	Pancreas	PDAC-A-st2	4.9e-07
FLVCR1	GOBP_Iron_Coordination_Entity_Transport	Human	Pancreas	PDAC-A-st2	7.0e-05
FLVCR1	GOBP_Erythrocyte_Maturation	Human	Uterus	rep_1	5.1e-06
FLVCR1	GOBP_Erythrocyte_Homeostasis	Human	Uterus	rep_25	2.8e-08
FLVCR1	GOBP_Organ_Growth	Human	Uterus	rep_25	6.1e-08
FLVCR1	GOBP_Regulation_Of_Organ_Growth	Human	Uterus	rep_25	2.7e-15
FLVCR1	GOBP_Anatomical_Structure_Maturation	Human	Uterus	rep_26	1.8e-09
FLVCR1	GOBP_Cell_Maturation	Human	Uterus	rep_26	4.6e-09
FLVCR1	GOBP_Cellular_Iron_Ion_Homeostasis	Human	Uterus	rep_26	4.7e-09
FLVCR1	GOBP_Developmental_Growth	Human	Uterus	rep_26	3.8e-06
FLVCR1	GOBP_Developmental_Maturation	Human	Uterus	rep_26	1.1e-06
FLVCR1	GOBP_Head_Morphogenesis	Human	Uterus	rep_26	1.4e-08
FLVCR1	GOBP_Heme_Transport	Human	Uterus	rep_26	2.4e-06
FLVCR1	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Uterus	rep_26	1.5e-12
FLVCR1	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
FLVCR1	GOBP_Immune_System_Development	Human	Uterus	rep_26	1.0e-06
FLVCR1	GOBP_Iron_Coordination_Entity_Transport	Human	Uterus	rep_26	3.1e-08
FLVCR1	GOBP_Iron_Ion_Transport	Human	Uterus	rep_26	2.6e-06
FLVCR1	GOBP_Myeloid_Cell_Homeostasis	Human	Uterus	rep_26	9.4e-15
FLVCR1	GOBP_Regulation_Of_Developmental_Growth	Human	Uterus	rep_26	6.9e-10
FLVCR1	GOBP_Transition_Metal_Ion_Transport	Human	Uterus	rep_26	1.3e-06
FLVCR1	GOBP_Myeloid_Cell_Differentiation	Human	Uterus	rep_29	2.6e-10
FLVCR1	GOBP_Animal_Organ_Morphogenesis	Human	Breast	rep_1	5.4e-25
FLVCR1	GOBP_Body_Morphogenesis	Human	Breast	rep_1	2.5e-08
FLVCR1	GOBP_Cation_Transport	Human	Breast	rep_1	8.4e-53
FLVCR1	GOBP_Cellular_Homeostasis	Human	Breast	rep_1	2.8e-10
FLVCR1	GOBP_Cellular_Ion_Homeostasis	Human	Breast	rep_1	7.6e-24
FLVCR1	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Human	Breast	rep_1	6.0e-07
FLVCR1	GOBP_Chemical_Homeostasis	Human	Breast	rep_1	4.8e-18
FLVCR1	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
FLVCR1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Human	Breast	rep_1	7.7e-07
FLVCR1	GOBP_Erythrocyte_Maturation	Human	Breast	rep_1	1.4e-40
FLVCR1	GOBP_Head_Development	Human	Breast	rep_1	1.0e-09
FLVCR1	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
FLVCR1	GOBP_Immune_System_Development	Human	Breast	rep_1	1.0e-31
FLVCR1	GOBP_In_Utero_Embryonic_Development	Human	Breast	rep_1	1.5e-18
FLVCR1	GOBP_Ion_Homeostasis	Human	Breast	rep_1	1.4e-53
FLVCR1	GOBP_Iron_Coordination_Entity_Transport	Human	Breast	rep_1	1.3e-172
FLVCR1	GOBP_Metal_Ion_Homeostasis	Human	Breast	rep_1	6.8e-70
FLVCR1	GOBP_Multicellular_Organism_Growth	Human	Breast	rep_1	2.9e-05
FLVCR1	GOBP_Myeloid_Cell_Development	Human	Breast	rep_1	7.5e-32
FLVCR1	GOBP_Myeloid_Cell_Differentiation	Human	Breast	rep_1	1.6e-14
FLVCR1	GOBP_Organ_Growth	Human	Breast	rep_1	3.7e-52
FLVCR1	GOBP_Regulation_Of_Developmental_Growth	Human	Breast	rep_1	1.2e-04
FLVCR1	GOBP_Regulation_Of_Growth	Human	Breast	rep_1	2.3e-04
FLVCR1	GOBP_Skeletal_System_Morphogenesis	Human	Breast	rep_1	6.7e-20
FLVCR1	GOBP_Transition_Metal_Ion_Homeostasis	Human	Breast	rep_1	1.1e-30
FLVCR1	GOBP_Transmembrane_Transport	Human	Breast	rep_1	3.2e-56
FLVCR1	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
FLVCR1	GOBP_Anatomical_Structure_Maturation	Human	Breast	rep_5	9.1e-14
FLVCR1	GOBP_Appendage_Development	Human	Breast	rep_5	1.7e-08
FLVCR1	GOBP_Cell_Maturation	Human	Breast	rep_5	1.3e-19
FLVCR1	GOBP_Developmental_Growth	Human	Breast	rep_5	1.6e-08
FLVCR1	GOBP_Developmental_Maturation	Human	Breast	rep_5	2.3e-12
FLVCR1	GOBP_Embryo_Development	Human	Breast	rep_5	5.5e-08
FLVCR1	GOBP_Embryonic_Digit_Morphogenesis	Human	Breast	rep_5	2.0e-04
FLVCR1	GOBP_Embryonic_Morphogenesis	Human	Breast	rep_5	2.0e-06
FLVCR1	GOBP_Embryonic_Organ_Development	Human	Breast	rep_5	3.3e-05
FLVCR1	GOBP_Growth	Human	Breast	rep_5	5.4e-12
FLVCR1	GOBP_Heme_Transport	Human	Breast	rep_5	1.4e-08
FLVCR1	GOBP_Spleen_Development	Human	Breast	rep_5	7.1e-08
FLVCR1	GOBP_Appendage_Morphogenesis	Human	Breast	rep_6	4.4e-06
FLVCR1	GOBP_Cellular_Iron_Ion_Homeostasis	Human	Breast	rep_6	2.3e-04
FLVCR1	GOBP_Embryonic_Appendage_Morphogenesis	Human	Breast	rep_6	7.6e-10
FLVCR1	GOBP_Embryonic_Organ_Morphogenesis	Human	Breast	rep_6	1.8e-08
FLVCR1	GOBP_Erythrocyte_Development	Human	Breast	rep_6	1.3e-07
FLVCR1	GOBP_Erythrocyte_Homeostasis	Human	Breast	rep_6	3.6e-05
FLVCR1	GOBP_Homeostasis_Of_Number_Of_Cells	Human	Breast	rep_6	5.1e-04
FLVCR1	GOBP_Mitochondrial_Transport	Human	Breast	rep_6	6.5e-10
FLVCR1	GOBP_Erythrocyte_Maturation	Human	Skin	P5_rep1	7.3e-12
FLVCR1	GOBP_Body_Morphogenesis	Human	Skin	P10_rep1	1.6e-13
FLVCR1	GOBP_Cellular_Iron_Ion_Homeostasis	Human	Skin	P10_rep1	2.8e-09
FLVCR1	GOBP_Erythrocyte_Development	Human	Skin	P10_rep1	2.5e-10
FLVCR1	GOBP_Head_Morphogenesis	Human	Skin	P10_rep1	6.3e-09
FLVCR1	GOBP_Iron_Ion_Transport	Human	Skin	P10_rep1	3.0e-10
FLVCR1	GOBP_Spleen_Development	Human	Skin	P10_rep1	5.0e-14
FLVCR1	GOBP_Ion_Homeostasis	Human	Lung	rep_1	6.1e-07
FLVCR1	GOBP_Iron_Ion_Homeostasis	Human	Lung	rep_1	2.2e-07
FLVCR1	GOBP_Iron_Ion_Transport	Human	Lung	rep_1	5.9e-07
FLVCR1	GOBP_Myeloid_Cell_Differentiation	Human	Lung	rep_1	8.1e-08
FLVCR1	GOBP_Transition_Metal_Ion_Transport	Human	Lung	rep_1	6.8e-07
FLVCR1	GOBP_Cellular_Homeostasis	Human	Lung	rep_2	7.3e-07
FLVCR1	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Human	Lung	rep_2	5.1e-07
FLVCR1	GOBP_Immune_System_Development	Human	Lung	rep_2	7.9e-07

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FLVCR1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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FLVCR1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for FLVCR1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for FLVCR1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for FLVCR1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
FLVCR1	C1836916	POSTERIOR COLUMN ATAXIA WITH RETINITIS PIGMENTOSA	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
FLVCR1	C2239176	Liver carcinoma	1	CTD_human