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Spatial pattern gene: ACAD9 (spascer ID:28976) |
Gene summary for ACAD9 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | ACAD9 | Gene ID | 28976 |
| Gene name | acyl-CoA dehydrogenase family member 9 |
| Synonyms | MC1DN20|NPD002 |
| Cytomap | 3q21.3 |
| Type of gene | protein-coding |
| Description | complex I assembly factor ACAD9, mitochondrialacyl-Coenzyme A dehydrogenase family, member 9very-long-chain acyl-CoA dehydrogenase VLCAD |
| Modification date | 20220513 |
| UniProtAcc | Q9H845 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| ACAD9 | GO:0000062 | fatty-acyl-CoA binding | 21873635 | Function |
| ACAD9 | GO:0003995 | acyl-CoA dehydrogenase activity | 21873635 | Function |
| ACAD9 | GO:0005739 | mitochondrion | 21873635 | Component |
| ACAD9 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity | 21873635 | Function |
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Spatial pattern events for ACAD9 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| ACAD9 | Human | Intestine | rep_colon4 | 34417225 | 1.56e-14 |
| ACAD9 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver2_H&E  |  |
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Spatial pattern pathway has ACAD9 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| ACAD9 | GOBP_Lipid_Metabolic_Process | Human | Brain | rep_1 | 2.8e-23 |
| ACAD9 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Bladder | rep_4 | 1.8e-09 |
| ACAD9 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Bladder | rep_4 | 1.1e-14 |
| ACAD9 | GOBP_Lipid_Metabolic_Process | Human | Liver | rep_1 | 1.0e-70 |
| ACAD9 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Intestine | A3 | 1.5e-07 |
| ACAD9 | GOBP_Mitochondrion_Organization | Human | Intestine | A3 | 2.3e-19 |
| ACAD9 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Intestine | A3 | 3.9e-07 |
| ACAD9 | GOBP_Cellular_Lipid_Metabolic_Process | Human | Intestine | A8 | 3.8e-13 |
| ACAD9 | GOBP_Fatty_Acid_Metabolic_Process | Human | Intestine | A8 | 7.3e-13 |
| ACAD9 | GOBP_Lipid_Metabolic_Process | Human | Intestine | A8 | 1.1e-11 |
| ACAD9 | GOBP_Long_Chain_Fatty_Acid_Metabolic_Process | Human | Intestine | A8 | 8.2e-09 |
| ACAD9 | GOBP_Monocarboxylic_Acid_Metabolic_Process | Human | Intestine | A8 | 7.3e-16 |
| ACAD9 | GOBP_Organic_Acid_Metabolic_Process | Human | Intestine | A8 | 2.5e-18 |
| ACAD9 | GOBP_Small_Molecule_Metabolic_Process | Human | Intestine | A8 | 2.1e-15 |
| ACAD9 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Pancreas | PDAC-B-st1 | 9.9e-05 |
| ACAD9 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Pancreas | PDAC-B-st1 | 4.6e-05 |
| ACAD9 | GOBP_Fatty_Acid_Metabolic_Process | Human | Uterus | rep_26 | 1.3e-06 |
| ACAD9 | GOBP_Long_Chain_Fatty_Acid_Metabolic_Process | Human | Uterus | rep_26 | 1.9e-09 |
| ACAD9 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Uterus | rep_26 | 2.3e-06 |
| ACAD9 | GOBP_Nadh_Dehydrogenase_Complex_Assembly | Human | Uterus | rep_26 | 9.9e-07 |
| ACAD9 | GOBP_Organic_Acid_Metabolic_Process | Human | Uterus | rep_26 | 4.9e-06 |
| ACAD9 | GOBP_Medium_Chain_Fatty_Acid_Metabolic_Process | Human | Uterus | rep_29 | 9.4e-06 |
| ACAD9 | GOBP_Cellular_Lipid_Metabolic_Process | Human | Breast | rep_5 | 2.6e-07 |
| ACAD9 | GOBP_Fatty_Acid_Metabolic_Process | Human | Breast | rep_5 | 1.2e-06 |
| ACAD9 | GOBP_Lipid_Metabolic_Process | Human | Breast | rep_5 | 2.9e-06 |
| ACAD9 | GOBP_Medium_Chain_Fatty_Acid_Metabolic_Process | Human | Breast | rep_5 | 2.9e-10 |
| ACAD9 | GOBP_Long_Chain_Fatty_Acid_Metabolic_Process | Human | Breast | rep_6 | 6.3e-10 |
| ACAD9 | GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly | Human | Breast | rep_6 | 3.3e-04 |
| ACAD9 | GOBP_Mitochondrion_Organization | Human | Breast | rep_6 | 2.0e-05 |
| ACAD9 | GOBP_Monocarboxylic_Acid_Metabolic_Process | Human | Breast | rep_6 | 6.1e-07 |
| ACAD9 | GOBP_Organic_Acid_Metabolic_Process | Human | Breast | rep_6 | 6.7e-05 |
| ACAD9 | GOBP_Small_Molecule_Metabolic_Process | Human | Breast | rep_6 | 5.5e-09 |
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ACAD9 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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ACAD9 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for ACAD9 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for ACAD9 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ACAD9 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| ACAD9 | C1970173 | Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of | 10 | CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET |
| ACAD9 | C4747517 | MITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 20 | 10 | GENOMICS_ENGLAND;UNIPROT |
