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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: AAMDC (spascer ID:28971)

Gene summary for AAMDC

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

AAMDC

Gene ID

28971

Gene nameadipogenesis associated Mth938 domain containing
SynonymsC11orf67|CK067|PTD015
Cytomap11q14.1
Type of geneprotein-coding
Descriptionmth938 domain-containing proteinUPF0366 protein C11orf67adipogenesis associated Mth938 domain-containing protein
Modification date20220513
UniProtAcc

Q9H7C9


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
AAMDC

GO:0005737

cytoplasm

21873635

Component
AAMDC

GO:0045600

positive regulation of fat cell differentiation

21873635

Process

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Spatial pattern events for AAMDC

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
AAMDCHumanIntestinerep_colon1 344172251.95e-15
AAMDCHumanIntestinerep_colon2 344172258.12e-16
AAMDCHumanIntestinerep_colon3 344172251.01e-15
AAMDCHumanLiverrep_liver2 344172256.98e-16

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon1_H&E
boxplot

boxplot
Intestine_rep_colon2_H&E
boxplot

boxplot
Intestine_rep_colon3_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot


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Spatial pattern pathway has AAMDC envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
AAMDCGOBP_Positive_Regulation_Of_Developmental_ProcessHumanBrainrep_4 4.1e-17
AAMDCGOBP_Positive_Regulation_Of_Fat_Cell_DifferentiationHumanBrainst 4.5e-22
AAMDCGOBP_Regulation_Of_Fat_Cell_DifferentiationHumanBrainst 1.2e-07
AAMDCGOBP_Positive_Regulation_Of_Developmental_ProcessHumanLiverrep_1 6.0e-76
AAMDCGOBP_Positive_Regulation_Of_Developmental_ProcessHumanIntestinerep_colon4 1.9e-09
AAMDCGOBP_Positive_Regulation_Of_Cell_DifferentiationHumanIntestineA3 1.6e-14
AAMDCGOBP_Positive_Regulation_Of_Developmental_ProcessHumanIntestineA3 1.5e-12
AAMDCGOBP_Regulation_Of_Cell_DifferentiationHumanIntestineA3 1.7e-10
AAMDCGOBP_Fat_Cell_DifferentiationHumanIntestineA8 2.4e-24
AAMDCGOBP_Positive_Regulation_Of_Fat_Cell_DifferentiationHumanIntestineA8 3.4e-18
AAMDCGOBP_Regulation_Of_Fat_Cell_DifferentiationHumanIntestineA8 5.6e-17
AAMDCGOBP_Positive_Regulation_Of_Fat_Cell_DifferentiationHumanPancreasPDAC-B-st1 8.5e-05
AAMDCGOBP_Fat_Cell_DifferentiationHumanUterusrep_26 3.8e-14
AAMDCGOBP_Positive_Regulation_Of_Cell_DifferentiationHumanUterusrep_26 1.6e-09
AAMDCGOBP_Positive_Regulation_Of_Developmental_ProcessHumanUterusrep_29 8.8e-06
AAMDCGOBP_Regulation_Of_Cell_DifferentiationHumanUterusrep_29 2.8e-06
AAMDCGOBP_Fat_Cell_DifferentiationHumanBreastrep_1 1.1e-26
AAMDCGOBP_Positive_Regulation_Of_Cell_DifferentiationHumanBreastrep_1 7.1e-96
AAMDCGOBP_Positive_Regulation_Of_Developmental_ProcessHumanBreastrep_1 1.4e-85
AAMDCGOBP_Positive_Regulation_Of_Fat_Cell_DifferentiationHumanBreastrep_1 1.3e-68
AAMDCGOBP_Regulation_Of_Cell_DifferentiationHumanBreastrep_1 2.5e-42

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AAMDC function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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AAMDC function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for AAMDC envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for AAMDC

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AAMDC

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource