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Spatial pattern gene: MRPS28 (spascer ID:28957) |
Gene summary for MRPS28 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | MRPS28 | Gene ID | 28957 |
| Gene name | mitochondrial ribosomal protein S28 |
| Synonyms | COXPD47|HSPC007|MRP-S28|MRP-S35|MRPS35 |
| Cytomap | 8q21.13 |
| Type of gene | protein-coding |
| Description | 28S ribosomal protein S28, mitochondrial28S ribosomal protein S35, mitochondrialS28mtS35mtmitochondrial 28S ribosomal protein S35mitochondrial small ribosomal subunit protein bS1m |
| Modification date | 20220513 |
| UniProtAcc | Q9Y2Q9 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| MRPS28 | GO:0005763 | mitochondrial small ribosomal subunit | 21873635 | Component |
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Spatial pattern events for MRPS28 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| MRPS28 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| MRPS28 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| MRPS28 | Human | Liver | rep_liver2 | 34417225 | 1.08e-06 |
| MRPS28 | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| MRPS28 | Human | Breast | 1142243F | 34493872 | 3.22e-08 |
| MRPS28 | Human | Breast | 1160920F | 34493872 | 1.35e-09 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_1160920F_H&E  |  |
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Spatial pattern pathway has MRPS28 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| MRPS28 | GOBP_Amide_Biosynthetic_Process | Human | Intestine | A1 | 6.4e-07 |
| MRPS28 | GOBP_Peptide_Biosynthetic_Process | Human | Intestine | A1 | 4.6e-10 |
| MRPS28 | GOBP_Translational_Elongation | Human | Intestine | A1 | 6.7e-08 |
| MRPS28 | GOBP_Translational_Termination | Human | Intestine | A1 | 3.9e-07 |
| MRPS28 | GOBP_Cellular_Component_Disassembly | Human | Intestine | A3 | 1.0e-14 |
| MRPS28 | GOBP_Mitochondrial_Gene_Expression | Human | Intestine | A8 | 1.4e-08 |
| MRPS28 | GOBP_Mitochondrial_Translation | Human | Intestine | A8 | 1.7e-08 |
| MRPS28 | GOBP_Mitochondrial_Translation | Human | Pancreas | PDAC-B-st1 | 5.1e-05 |
| MRPS28 | GOBP_Translational_Termination | Human | Uterus | rep_1 | 5.2e-09 |
| MRPS28 | GOBP_Mitochondrial_Translation | Human | Uterus | rep_25 | 3.6e-06 |
| MRPS28 | GOBP_Translational_Elongation | Human | Uterus | rep_25 | 9.9e-08 |
| MRPS28 | GOBP_Cellular_Component_Disassembly | Human | Uterus | rep_26 | 2.7e-06 |
| MRPS28 | GOBP_Mitochondrial_Gene_Expression | Human | Uterus | rep_26 | 1.3e-15 |
| MRPS28 | GOBP_Translational_Termination | Human | Breast | rep_1 | 7.0e-06 |
| MRPS28 | GOBP_Cellular_Component_Disassembly | Human | Breast | rep_5 | 2.0e-06 |
| MRPS28 | GOBP_Amide_Biosynthetic_Process | Human | Breast | rep_6 | 8.7e-05 |
| MRPS28 | GOBP_Cellular_Amide_Metabolic_Process | Human | Breast | rep_6 | 5.6e-05 |
| MRPS28 | GOBP_Mitochondrial_Gene_Expression | Human | Breast | rep_6 | 9.9e-07 |
| MRPS28 | GOBP_Mitochondrial_Translation | Human | Breast | rep_6 | 1.3e-06 |
| MRPS28 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Human | Breast | rep_6 | 1.2e-09 |
| MRPS28 | GOBP_Peptide_Biosynthetic_Process | Human | Breast | rep_6 | 1.6e-05 |
| MRPS28 | GOBP_Peptide_Metabolic_Process | Human | Breast | rep_6 | 8.7e-05 |
| MRPS28 | GOBP_Protein_Containing_Complex_Disassembly | Human | Breast | rep_6 | 1.0e-13 |
| MRPS28 | GOBP_Translational_Termination | Human | Skin | P10_rep1 | 6.7e-10 |
| MRPS28 | GOBP_Cellular_Component_Disassembly | Human | Lung | rep_2 | 5.6e-07 |
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MRPS28 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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MRPS28 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for MRPS28 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for MRPS28 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MRPS28 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| MRPS28 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| MRPS28 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| MRPS28 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| MRPS28 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| MRPS28 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
