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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: RAPGEF1 (spascer ID:2889)

Gene summary for RAPGEF1

Gene summary

Gene information
	Species	Human
	Gene symbol	RAPGEF1
	Gene ID	2889
	Gene name	Rap guanine nucleotide exchange factor 1
	Synonyms	C3G\|GRF2
	Cytomap	9q34.13
	Type of gene	protein-coding
	Description	rap guanine nucleotide exchange factor 1CRK SH3-binding GNRPRap guanine nucleotide exchange factor (GEF) 1guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
	Modification date	20220513
	UniProtAcc	Q13905

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
RAPGEF1	GO:0005085	guanyl-nucleotide exchange factor activity	21873635	Function
RAPGEF1	GO:0005886	plasma membrane	21873635	Component
RAPGEF1	GO:0007265	Ras protein signal transduction	21873635	Process
RAPGEF1	GO:0043547	positive regulation of GTPase activity	21873635	Process

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Spatial pattern events for RAPGEF1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
RAPGEF1	Human	Intestine	rep_colon1	34417225	3.42e-15
RAPGEF1	Human	Intestine	rep_colon2	34417225	2.55e-13
RAPGEF1	Human	Intestine	rep_colon3	34417225	1.01e-15
RAPGEF1	Human	Intestine	rep_colon4	34417225	1.14e-15
RAPGEF1	Human	Liver	rep_liver2	34417225	2.49e-15
RAPGEF1	Human	Intestine	A1	33406409	6.31e-15
RAPGEF1	Human	Intestine	A2	33406409	1.97e-07
RAPGEF1	Human	Uterus	rep_3	34857954	1.66e-15
RAPGEF1	Human	Breast	1142243F	34493872	3.37e-06
RAPGEF1	Human	Breast	1160920F	34493872	1.48e-15
RAPGEF1	Human	Breast	CID44971	34493872	6.50e-10
RAPGEF1	Human	Skin	P2_rep3	32946785	9.83e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver2_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_3_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E
Skin_P2_rep3_H&E

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Spatial pattern pathway has RAPGEF1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
RAPGEF1	GOBP_Activation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
RAPGEF1	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Brain	rep_1	2.3e-68
RAPGEF1	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
RAPGEF1	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
RAPGEF1	GOBP_Neuron_Development	Human	Brain	rep_1	7.4e-34
RAPGEF1	GOBP_Neuron_Differentiation	Human	Brain	rep_1	7.4e-34
RAPGEF1	GOBP_Phagocytosis	Human	Brain	rep_1	3.1e-16
RAPGEF1	GOBP_Platelet_Derived_Growth_Factor_Receptor_Signaling_Pathway	Human	Brain	rep_1	2.3e-68
RAPGEF1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
RAPGEF1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
RAPGEF1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	3.1e-68
RAPGEF1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
RAPGEF1	GOBP_Positive_Regulation_Of_Phagocytosis	Human	Brain	rep_1	3.1e-16
RAPGEF1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	2.8e-23
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	2.8e-23
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	2.8e-23
RAPGEF1	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
RAPGEF1	GOBP_Positive_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
RAPGEF1	GOBP_Protein_Kinase_B_Signaling	Human	Brain	rep_1	3.1e-68
RAPGEF1	GOBP_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
RAPGEF1	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
RAPGEF1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Brain	rep_1	1.2e-64
RAPGEF1	GOBP_Regulation_Of_Phagocytosis	Human	Brain	rep_1	3.1e-16
RAPGEF1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	7.4e-34
RAPGEF1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
RAPGEF1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	7.4e-34
RAPGEF1	GOBP_Regulation_Of_Response_To_Stress	Human	Brain	rep_1	4.6e-05
RAPGEF1	GOBP_Regulation_Of_Transport	Human	Brain	rep_1	3.1e-16
RAPGEF1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Human	Brain	rep_1	3.1e-16
RAPGEF1	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Brain	rep_1	2.3e-68
RAPGEF1	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
RAPGEF1	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
RAPGEF1	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
RAPGEF1	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
RAPGEF1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
RAPGEF1	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
RAPGEF1	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Bladder	rep_2	1.3e-05
RAPGEF1	GOBP_Positive_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Bladder	rep_2	1.1e-20
RAPGEF1	GOBP_Response_To_Camp	Human	Bladder	rep_2	2.6e-14
RAPGEF1	GOBP_Response_To_Growth_Factor	Human	Bladder	rep_2	1.2e-08
RAPGEF1	GOBP_Response_To_Purine_Containing_Compound	Human	Bladder	rep_2	5.7e-20
RAPGEF1	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
RAPGEF1	GOBP_Activation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
RAPGEF1	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
RAPGEF1	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Liver	rep_1	8.8e-90
RAPGEF1	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
RAPGEF1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Liver	rep_1	2.8e-53
RAPGEF1	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
RAPGEF1	GOBP_Neuron_Development	Human	Liver	rep_1	1.5e-73
RAPGEF1	GOBP_Neuron_Differentiation	Human	Liver	rep_1	1.5e-73
RAPGEF1	GOBP_Phagocytosis	Human	Liver	rep_1	3.2e-72
RAPGEF1	GOBP_Platelet_Derived_Growth_Factor_Receptor_Signaling_Pathway	Human	Liver	rep_1	8.8e-90
RAPGEF1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
RAPGEF1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
RAPGEF1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
RAPGEF1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
RAPGEF1	GOBP_Positive_Regulation_Of_Phagocytosis	Human	Liver	rep_1	3.2e-72
RAPGEF1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
RAPGEF1	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
RAPGEF1	GOBP_Positive_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
RAPGEF1	GOBP_Protein_Kinase_B_Signaling	Human	Liver	rep_1	1.9e-71
RAPGEF1	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
RAPGEF1	GOBP_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
RAPGEF1	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
RAPGEF1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Liver	rep_1	6.9e-47
RAPGEF1	GOBP_Regulation_Of_Phagocytosis	Human	Liver	rep_1	3.2e-72
RAPGEF1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
RAPGEF1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
RAPGEF1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
RAPGEF1	GOBP_Regulation_Of_Response_To_Stress	Human	Liver	rep_1	5.3e-67
RAPGEF1	GOBP_Regulation_Of_Transport	Human	Liver	rep_1	9.4e-68
RAPGEF1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Human	Liver	rep_1	3.2e-72
RAPGEF1	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
RAPGEF1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
RAPGEF1	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Liver	rep_1	8.8e-90
RAPGEF1	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
RAPGEF1	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Intestine	rep_colon2	5.0e-29
RAPGEF1	GOBP_Platelet_Derived_Growth_Factor_Receptor_Signaling_Pathway	Human	Intestine	rep_colon2	5.0e-29
RAPGEF1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
RAPGEF1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
RAPGEF1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	3.4e-10
RAPGEF1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
RAPGEF1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	rep_colon2	2.4e-25
RAPGEF1	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Intestine	rep_colon2	5.0e-29
RAPGEF1	GOBP_Activation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
RAPGEF1	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
RAPGEF1	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
RAPGEF1	GOBP_Phagocytosis	Human	Intestine	rep_colon4	7.4e-22
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
RAPGEF1	GOBP_Positive_Regulation_Of_Phagocytosis	Human	Intestine	rep_colon4	7.4e-22
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
RAPGEF1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
RAPGEF1	GOBP_Positive_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
RAPGEF1	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
RAPGEF1	GOBP_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
RAPGEF1	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
RAPGEF1	GOBP_Regulation_Of_Phagocytosis	Human	Intestine	rep_colon4	7.4e-22
RAPGEF1	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	rep_colon4	2.2e-52
RAPGEF1	GOBP_Regulation_Of_Transport	Human	Intestine	rep_colon4	1.0e-26
RAPGEF1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Human	Intestine	rep_colon4	7.4e-22
RAPGEF1	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
RAPGEF1	GOBP_Protein_Kinase_B_Signaling	Human	Intestine	rep_liver2	1.0e-64
RAPGEF1	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
RAPGEF1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
RAPGEF1	GOBP_Activation_Of_Immune_Response	Human	Intestine	A3	5.7e-11
RAPGEF1	GOBP_Biological_Adhesion	Human	Intestine	A3	6.7e-11
RAPGEF1	GOBP_Cell_Cell_Adhesion	Human	Intestine	A3	2.5e-07
RAPGEF1	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
RAPGEF1	GOBP_Cell_Cell_Signaling_By_Wnt	Human	Intestine	A3	3.1e-07
RAPGEF1	GOBP_Cell_Junction_Assembly	Human	Intestine	A3	6.2e-12
RAPGEF1	GOBP_Cell_Junction_Organization	Human	Intestine	A3	1.1e-08
RAPGEF1	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
RAPGEF1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Human	Intestine	A3	7.0e-07
RAPGEF1	GOBP_Cellular_Response_To_Camp	Human	Intestine	A3	9.3e-09
RAPGEF1	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	2.5e-14
RAPGEF1	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
RAPGEF1	GOBP_Cytokine_Mediated_Signaling_Pathway	Human	Intestine	A3	2.6e-09
RAPGEF1	GOBP_Erk1_And_Erk2_Cascade	Human	Intestine	A3	2.6e-07
RAPGEF1	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
RAPGEF1	GOBP_Immune_Response_Regulating_Signaling_Pathway	Human	Intestine	A3	2.2e-11
RAPGEF1	GOBP_Jnk_Cascade	Human	Intestine	A3	3.8e-08
RAPGEF1	GOBP_Mapk_Cascade	Human	Intestine	A3	1.1e-12
RAPGEF1	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Human	Intestine	A3	1.6e-07
RAPGEF1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	5.4e-19
RAPGEF1	GOBP_Negative_Regulation_Of_Erk1_And_Erk2_Cascade	Human	Intestine	A3	7.7e-09
RAPGEF1	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	2.6e-18
RAPGEF1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Intestine	A3	6.0e-11
RAPGEF1	GOBP_Negative_Regulation_Of_Signaling	Human	Intestine	A3	4.9e-15
RAPGEF1	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Human	Intestine	A3	1.2e-10
RAPGEF1	GOBP_Neural_Precursor_Cell_Proliferation	Human	Intestine	A3	8.9e-11
RAPGEF1	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
RAPGEF1	GOBP_Neuron_Development	Human	Intestine	A3	1.3e-12
RAPGEF1	GOBP_Neuron_Differentiation	Human	Intestine	A3	1.4e-11
RAPGEF1	GOBP_Phagocytosis	Human	Intestine	A3	2.4e-07
RAPGEF1	GOBP_Platelet_Derived_Growth_Factor_Receptor_Signaling_Pathway	Human	Intestine	A3	4.7e-07
RAPGEF1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
RAPGEF1	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	1.2e-09
RAPGEF1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
RAPGEF1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.8e-12
RAPGEF1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_Response	Human	Intestine	A3	2.4e-07
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	A3	6.8e-15
RAPGEF1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	2.6e-10
RAPGEF1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
RAPGEF1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	7.8e-15
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	9.1e-12
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	2.0e-08
RAPGEF1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
RAPGEF1	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Intestine	A3	2.1e-11
RAPGEF1	GOBP_Positive_Regulation_Of_Transport	Human	Intestine	A3	9.5e-08
RAPGEF1	GOBP_Regulation_Of_Cell_Junction_Assembly	Human	Intestine	A3	3.1e-14
RAPGEF1	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
RAPGEF1	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
RAPGEF1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Intestine	A3	7.7e-17
RAPGEF1	GOBP_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.0e-12
RAPGEF1	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
RAPGEF1	GOBP_Regulation_Of_Immune_Response	Human	Intestine	A3	1.6e-12
RAPGEF1	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
RAPGEF1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Intestine	A3	7.5e-12
RAPGEF1	GOBP_Regulation_Of_Neural_Precursor_Cell_Proliferation	Human	Intestine	A3	2.0e-08
RAPGEF1	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Intestine	A3	2.0e-09
RAPGEF1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	1.5e-11
RAPGEF1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
RAPGEF1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	8.8e-11
RAPGEF1	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	A3	1.1e-10
RAPGEF1	GOBP_Regulation_Of_Transferase_Activity	Human	Intestine	A3	3.9e-10
RAPGEF1	GOBP_Regulation_Of_Transport	Human	Intestine	A3	4.4e-11
RAPGEF1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Human	Intestine	A3	1.3e-11
RAPGEF1	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
RAPGEF1	GOBP_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	3.2e-15
RAPGEF1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
RAPGEF1	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Intestine	A3	1.7e-07
RAPGEF1	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Intestine	A3	2.0e-11
RAPGEF1	GOBP_Activation_Of_Gtpase_Activity	Human	Intestine	A8	1.0e-11
RAPGEF1	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
RAPGEF1	GOBP_Endothelial_Cell_Development	Human	Intestine	A8	1.7e-10
RAPGEF1	GOBP_Epithelial_Cell_Differentiation	Human	Intestine	A8	6.8e-07
RAPGEF1	GOBP_Establishment_Of_Endothelial_Barrier	Human	Intestine	A8	7.4e-09
RAPGEF1	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Intestine	A8	3.3e-11
RAPGEF1	GOBP_Fc_Receptor_Signaling_Pathway	Human	Intestine	A8	1.1e-15
RAPGEF1	GOBP_Negative_Regulation_Of_Mapk_Cascade	Human	Intestine	A8	1.2e-15
RAPGEF1	GOBP_Negative_Regulation_Of_Neural_Precursor_Cell_Proliferation	Human	Intestine	A8	3.5e-15
RAPGEF1	GOBP_Negative_Regulation_Of_Protein_Kinase_B_Signaling	Human	Intestine	A8	5.5e-15
RAPGEF1	GOBP_Neurotrophin_Signaling_Pathway	Human	Intestine	A8	1.1e-11
RAPGEF1	GOBP_Positive_Regulation_Of_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Intestine	A8	9.3e-20
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_Effector_Process	Human	Intestine	A8	1.1e-14
RAPGEF1	GOBP_Positive_Regulation_Of_Phagocytosis	Human	Intestine	A8	4.2e-10
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Intestine	A8	1.1e-12
RAPGEF1	GOBP_Protein_Kinase_B_Signaling	Human	Intestine	A8	4.5e-10
RAPGEF1	GOBP_Ras_Protein_Signal_Transduction	Human	Intestine	A8	6.4e-07
RAPGEF1	GOBP_Regulation_Of_Immune_Effector_Process	Human	Intestine	A8	2.4e-12
RAPGEF1	GOBP_Regulation_Of_Jnk_Cascade	Human	Intestine	A8	2.0e-08
RAPGEF1	GOBP_Regulation_Of_Phagocytosis	Human	Intestine	A8	8.7e-10
RAPGEF1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Intestine	A8	3.1e-07
RAPGEF1	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Intestine	A8	4.3e-23
RAPGEF1	GOBP_Response_To_Camp	Human	Intestine	A8	1.4e-17
RAPGEF1	GOBP_Response_To_Cytokine	Human	Intestine	A8	1.6e-08
RAPGEF1	GOBP_Response_To_Nerve_Growth_Factor	Human	Intestine	A8	8.7e-16
RAPGEF1	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
RAPGEF1	GOBP_Response_To_Purine_Containing_Compound	Human	Intestine	A8	1.7e-20
RAPGEF1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Human	Intestine	A8	7.1e-10
RAPGEF1	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
RAPGEF1	GOBP_Cellular_Response_To_Camp	Human	Pancreas	PDAC-B-st1	8.8e-06
RAPGEF1	GOBP_Establishment_Of_Endothelial_Barrier	Human	Pancreas	PDAC-B-st1	3.9e-05
RAPGEF1	GOBP_Fc_Receptor_Signaling_Pathway	Human	Pancreas	PDAC-B-st1	5.7e-05
RAPGEF1	GOBP_Negative_Regulation_Of_Signaling	Human	Pancreas	PDAC-B-st1	1.7e-05
RAPGEF1	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Human	Pancreas	PDAC-B-st1	4.2e-05
RAPGEF1	GOBP_Platelet_Derived_Growth_Factor_Receptor_Signaling_Pathway	Human	Pancreas	PDAC-B-st1	6.7e-06
RAPGEF1	GOBP_Positive_Regulation_Of_Mapk_Cascade	Human	Pancreas	PDAC-B-st1	1.1e-05
RAPGEF1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Pancreas	PDAC-B-st1	8.9e-05
RAPGEF1	GOBP_Ras_Protein_Signal_Transduction	Human	Pancreas	PDAC-B-st1	9.4e-05
RAPGEF1	GOBP_Regulation_Of_Gtpase_Activity	Human	Pancreas	PDAC-B-st1	9.7e-05
RAPGEF1	GOBP_Regulation_Of_Jnk_Cascade	Human	Pancreas	PDAC-B-st1	4.6e-05
RAPGEF1	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Human	Pancreas	PDAC-B-st1	4.8e-05
RAPGEF1	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Pancreas	PDAC-B-st1	1.6e-06
RAPGEF1	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Pancreas	PDAC-B-st1	3.7e-05
RAPGEF1	GOBP_Activation_Of_Gtpase_Activity	Human	Pancreas	PDAC-A-st2	4.8e-06
RAPGEF1	GOBP_Epithelial_Cell_Development	Human	Pancreas	PDAC-A-st2	5.9e-05
RAPGEF1	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Pancreas	PDAC-A-st2	1.9e-07
RAPGEF1	GOBP_Activation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
RAPGEF1	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
RAPGEF1	GOBP_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
RAPGEF1	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
RAPGEF1	GOBP_Fc_Receptor_Signaling_Pathway	Human	Uterus	rep_25	8.9e-13
RAPGEF1	GOBP_Nerve_Growth_Factor_Signaling_Pathway	Human	Uterus	rep_25	1.4e-07
RAPGEF1	GOBP_Neurotrophin_Signaling_Pathway	Human	Uterus	rep_25	1.2e-09
RAPGEF1	GOBP_Positive_Regulation_Of_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Uterus	rep_25	3.0e-11
RAPGEF1	GOBP_Rap_Protein_Signal_Transduction	Human	Uterus	rep_25	3.4e-11
RAPGEF1	GOBP_Activation_Of_Gtpase_Activity	Human	Uterus	rep_26	2.2e-07
RAPGEF1	GOBP_Activation_Of_Protein_Kinase_Activity	Human	Uterus	rep_26	2.8e-13
RAPGEF1	GOBP_Cell_Cell_Signaling_By_Wnt	Human	Uterus	rep_26	5.5e-06
RAPGEF1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Human	Uterus	rep_26	9.2e-08
RAPGEF1	GOBP_Cytokine_Mediated_Signaling_Pathway	Human	Uterus	rep_26	2.0e-10
RAPGEF1	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Uterus	rep_26	3.7e-06
RAPGEF1	GOBP_Jnk_Cascade	Human	Uterus	rep_26	2.0e-08
RAPGEF1	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Human	Uterus	rep_26	2.7e-06
RAPGEF1	GOBP_Negative_Regulation_Of_Protein_Kinase_B_Signaling	Human	Uterus	rep_26	6.9e-06
RAPGEF1	GOBP_Negative_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Uterus	rep_26	1.1e-08
RAPGEF1	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Human	Uterus	rep_26	1.4e-06
RAPGEF1	GOBP_Neural_Precursor_Cell_Proliferation	Human	Uterus	rep_26	1.9e-08
RAPGEF1	GOBP_Positive_Regulation_Of_Erk1_And_Erk2_Cascade	Human	Uterus	rep_26	1.1e-06
RAPGEF1	GOBP_Positive_Regulation_Of_Phagocytosis	Human	Uterus	rep_26	1.3e-08
RAPGEF1	GOBP_Ras_Protein_Signal_Transduction	Human	Uterus	rep_26	7.0e-12
RAPGEF1	GOBP_Regulation_Of_Fc_Gamma_Receptor_Signaling_Pathway_Involved_In_Phagocytosis	Human	Uterus	rep_26	1.3e-13
RAPGEF1	GOBP_Regulation_Of_Phagocytosis	Human	Uterus	rep_26	2.8e-11
RAPGEF1	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Human	Uterus	rep_26	1.0e-06
RAPGEF1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Uterus	rep_26	9.8e-09
RAPGEF1	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Uterus	rep_26	7.8e-06
RAPGEF1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Human	Uterus	rep_26	3.4e-11
RAPGEF1	GOBP_Regulation_Of_Wnt_Signaling_Pathway	Human	Uterus	rep_26	9.9e-10
RAPGEF1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Human	Uterus	rep_26	4.7e-08
RAPGEF1	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Uterus	rep_26	3.2e-09
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_Effector_Process	Human	Uterus	rep_28	3.5e-07
RAPGEF1	GOBP_Regulation_Of_Immune_Effector_Process	Human	Uterus	rep_28	5.1e-07
RAPGEF1	GOBP_Biological_Adhesion	Human	Uterus	rep_29	3.3e-06
RAPGEF1	GOBP_Erk1_And_Erk2_Cascade	Human	Uterus	rep_29	7.0e-08
RAPGEF1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Uterus	rep_29	1.2e-06
RAPGEF1	GOBP_Negative_Regulation_Of_Signaling	Human	Uterus	rep_29	5.3e-06
RAPGEF1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Uterus	rep_29	5.5e-06
RAPGEF1	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
RAPGEF1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_29	2.8e-06
RAPGEF1	GOBP_Activation_Of_Gtpase_Activity	Human	Breast	rep_1	5.7e-24
RAPGEF1	GOBP_Biological_Adhesion	Human	Breast	rep_1	4.0e-110
RAPGEF1	GOBP_Cell_Cell_Adhesion	Human	Breast	rep_1	3.6e-45
RAPGEF1	GOBP_Cell_Junction_Assembly	Human	Breast	rep_1	4.4e-63
RAPGEF1	GOBP_Cell_Junction_Organization	Human	Breast	rep_1	3.0e-10
RAPGEF1	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
RAPGEF1	GOBP_Cellular_Response_To_Camp	Human	Breast	rep_1	4.1e-13
RAPGEF1	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
RAPGEF1	GOBP_Cytokine_Mediated_Signaling_Pathway	Human	Breast	rep_1	1.5e-144
RAPGEF1	GOBP_Endothelial_Cell_Development	Human	Breast	rep_1	2.1e-67
RAPGEF1	GOBP_Endothelium_Development	Human	Breast	rep_1	4.9e-08
RAPGEF1	GOBP_Epithelial_Cell_Differentiation	Human	Breast	rep_1	4.5e-30
RAPGEF1	GOBP_Epithelium_Development	Human	Breast	rep_1	2.0e-22
RAPGEF1	GOBP_Establishment_Of_Endothelial_Barrier	Human	Breast	rep_1	5.7e-27
RAPGEF1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	1.3e-54
RAPGEF1	GOBP_Negative_Regulation_Of_Erk1_And_Erk2_Cascade	Human	Breast	rep_1	5.7e-07
RAPGEF1	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_1	3.6e-04
RAPGEF1	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Breast	rep_1	2.4e-07
RAPGEF1	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
RAPGEF1	GOBP_Neuron_Development	Human	Breast	rep_1	2.5e-26
RAPGEF1	GOBP_Neuron_Differentiation	Human	Breast	rep_1	1.1e-16
RAPGEF1	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	1.6e-25
RAPGEF1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
RAPGEF1	GOBP_Positive_Regulation_Of_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Breast	rep_1	4.5e-30
RAPGEF1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	1.4e-13
RAPGEF1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
RAPGEF1	GOBP_Positive_Regulation_Of_Phagocytosis	Human	Breast	rep_1	4.3e-175
RAPGEF1	GOBP_Positive_Regulation_Of_Transport	Human	Breast	rep_1	3.1e-10
RAPGEF1	GOBP_Rap_Protein_Signal_Transduction	Human	Breast	rep_1	9.9e-17
RAPGEF1	GOBP_Regulation_Of_Cell_Junction_Assembly	Human	Breast	rep_1	8.1e-17
RAPGEF1	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
RAPGEF1	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
RAPGEF1	GOBP_Regulation_Of_Fc_Gamma_Receptor_Signaling_Pathway_Involved_In_Phagocytosis	Human	Breast	rep_1	1.9e-50
RAPGEF1	GOBP_Regulation_Of_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Breast	rep_1	2.4e-25
RAPGEF1	GOBP_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	9.6e-08
RAPGEF1	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Breast	rep_1	7.3e-24
RAPGEF1	GOBP_Regulation_Of_Phagocytosis	Human	Breast	rep_1	6.9e-38
RAPGEF1	GOBP_Regulation_Of_Response_To_Stress	Human	Breast	rep_1	3.4e-19
RAPGEF1	GOBP_Regulation_Of_Transport	Human	Breast	rep_1	3.7e-17
RAPGEF1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Human	Breast	rep_1	4.9e-41
RAPGEF1	GOBP_Response_To_Camp	Human	Breast	rep_1	1.1e-83
RAPGEF1	GOBP_Response_To_Cytokine	Human	Breast	rep_1	2.5e-24
RAPGEF1	GOBP_Response_To_Growth_Factor	Human	Breast	rep_1	1.2e-13
RAPGEF1	GOBP_Response_To_Purine_Containing_Compound	Human	Breast	rep_1	4.8e-85
RAPGEF1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Human	Breast	rep_1	3.4e-04
RAPGEF1	GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_Pathway	Human	Breast	rep_1	1.4e-14
RAPGEF1	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
RAPGEF1	GOBP_Cellular_Response_To_Nitrogen_Compound	Human	Breast	rep_5	4.4e-13
RAPGEF1	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	5.1e-18
RAPGEF1	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
RAPGEF1	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Breast	rep_5	4.6e-14
RAPGEF1	GOBP_Epithelial_Cell_Development	Human	Breast	rep_5	1.8e-05
RAPGEF1	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Breast	rep_5	1.9e-07
RAPGEF1	GOBP_Fc_Receptor_Signaling_Pathway	Human	Breast	rep_5	9.4e-16
RAPGEF1	GOBP_Jnk_Cascade	Human	Breast	rep_5	4.2e-05
RAPGEF1	GOBP_Mapk_Cascade	Human	Breast	rep_5	4.6e-17
RAPGEF1	GOBP_Negative_Regulation_Of_Signaling	Human	Breast	rep_5	8.6e-14
RAPGEF1	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Human	Breast	rep_5	4.8e-05
RAPGEF1	GOBP_Nerve_Growth_Factor_Signaling_Pathway	Human	Breast	rep_5	4.2e-08
RAPGEF1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
RAPGEF1	GOBP_Positive_Regulation_Of_Erk1_And_Erk2_Cascade	Human	Breast	rep_5	4.3e-05
RAPGEF1	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	5.3e-08
RAPGEF1	GOBP_Positive_Regulation_Of_Mapk_Cascade	Human	Breast	rep_5	1.9e-16
RAPGEF1	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
RAPGEF1	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	5.9e-12
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	3.0e-10
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	1.0e-15
RAPGEF1	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
RAPGEF1	GOBP_Positive_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Breast	rep_5	1.8e-09
RAPGEF1	GOBP_Ras_Protein_Signal_Transduction	Human	Breast	rep_5	2.7e-06
RAPGEF1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Breast	rep_5	8.1e-10
RAPGEF1	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
RAPGEF1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Human	Breast	rep_5	8.7e-11
RAPGEF1	GOBP_Regulation_Of_Jnk_Cascade	Human	Breast	rep_5	5.1e-06
RAPGEF1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	2.5e-06
RAPGEF1	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_5	1.4e-06
RAPGEF1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
RAPGEF1	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	5.8e-14
RAPGEF1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Human	Breast	rep_5	2.0e-07
RAPGEF1	GOBP_Regulation_Of_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Breast	rep_5	9.2e-08
RAPGEF1	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
RAPGEF1	GOBP_Response_To_Nerve_Growth_Factor	Human	Breast	rep_5	9.1e-19
RAPGEF1	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
RAPGEF1	GOBP_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	7.5e-14
RAPGEF1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
RAPGEF1	GOBP_Stress_Activated_Protein_Kinase_Signaling_Cascade	Human	Breast	rep_5	1.3e-07
RAPGEF1	GOBP_Activation_Of_Protein_Kinase_Activity	Human	Breast	rep_6	1.8e-04
RAPGEF1	GOBP_Canonical_Wnt_Signaling_Pathway	Human	Breast	rep_6	6.4e-04
RAPGEF1	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
RAPGEF1	GOBP_Cell_Cell_Signaling_By_Wnt	Human	Breast	rep_6	4.2e-06
RAPGEF1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Human	Breast	rep_6	1.5e-06
RAPGEF1	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Human	Breast	rep_6	2.1e-06
RAPGEF1	GOBP_Negative_Regulation_Of_Mapk_Cascade	Human	Breast	rep_6	4.5e-09
RAPGEF1	GOBP_Negative_Regulation_Of_Neural_Precursor_Cell_Proliferation	Human	Breast	rep_6	1.3e-06
RAPGEF1	GOBP_Negative_Regulation_Of_Protein_Kinase_B_Signaling	Human	Breast	rep_6	4.4e-10
RAPGEF1	GOBP_Neural_Precursor_Cell_Proliferation	Human	Breast	rep_6	2.0e-05
RAPGEF1	GOBP_Neurotrophin_Signaling_Pathway	Human	Breast	rep_6	1.7e-04
RAPGEF1	GOBP_Platelet_Derived_Growth_Factor_Receptor_Signaling_Pathway	Human	Breast	rep_6	3.3e-09
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_6	1.5e-05
RAPGEF1	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	3.2e-05
RAPGEF1	GOBP_Protein_Kinase_B_Signaling	Human	Breast	rep_6	1.5e-08
RAPGEF1	GOBP_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	4.6e-05
RAPGEF1	GOBP_Regulation_Of_Fc_Gamma_Receptor_Signaling_Pathway_Involved_In_Phagocytosis	Human	Skin	P2_rep2	7.8e-10
RAPGEF1	GOBP_Negative_Regulation_Of_Protein_Kinase_B_Signaling	Human	Skin	P5_rep1	1.5e-09
RAPGEF1	GOBP_Epithelium_Development	Human	Skin	P9_rep3	4.2e-08
RAPGEF1	GOBP_Negative_Regulation_Of_Erk1_And_Erk2_Cascade	Human	Skin	P10_rep1	7.6e-16
RAPGEF1	GOBP_Regulation_Of_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Human	Skin	P10_rep2	4.5e-09
RAPGEF1	GOBP_Negative_Regulation_Of_Neural_Precursor_Cell_Proliferation	Human	Skin	P10_rep3	4.6e-14
RAPGEF1	GOBP_Platelet_Derived_Growth_Factor_Receptor_Signaling_Pathway	Human	Lung	rep_1	3.3e-09
RAPGEF1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	3.1e-08
RAPGEF1	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	7.4e-09
RAPGEF1	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
RAPGEF1	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
RAPGEF1	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	3.2e-09
RAPGEF1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08
RAPGEF1	GOBP_Biological_Adhesion	Human	Lung	rep_2	6.6e-07
RAPGEF1	GOBP_Cell_Cell_Adhesion	Human	Lung	rep_2	5.3e-07
RAPGEF1	GOBP_Immune_Response_Regulating_Signaling_Pathway	Human	Lung	rep_2	1.2e-08
RAPGEF1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07
RAPGEF1	GOBP_Positive_Regulation_Of_Neuron_Projection_Development	Human	Lung	rep_2	4.3e-10

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RAPGEF1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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RAPGEF1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for RAPGEF1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for RAPGEF1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for RAPGEF1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source