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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: GPT (spascer ID:2875)

Gene summary for GPT

Gene summary

Gene information
	Species	Human
	Gene symbol	GPT
	Gene ID	2875
	Gene name	glutamic--pyruvic transaminase
	Synonyms	AAT1\|ALT1\|GPT1
	Cytomap	8q24.3
	Type of gene	protein-coding
	Description	alanine aminotransferase 1alanine aminotransferasealanine transaminaseglutamate pyruvate transaminase 1glutamic--pyruvic transaminase 1glutamic-alanine transaminase 1glutamic-pyruvate transaminase (alanine aminotransferase)
	Modification date	20220513
	UniProtAcc	P24298

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for GPT

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
GPT	Human	Intestine	rep_colon4	34417225	1.14e-15
GPT	Human	Liver	rep_liver1	34417225	3.57e-15
GPT	Human	Liver	rep_liver2	34417225	6.98e-16
GPT	Human	Liver	rep_liver3	34417225	2.84e-08
GPT	Human	Intestine	A1	33406409	3.78e-11
GPT	Human	Intestine	A2	33406409	5.17e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Intestine_A1_H&E
Intestine_A2_H&E

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Spatial pattern pathway has GPT envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
GPT	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
GPT	GOBP_Response_To_Hormone	Human	Brain	rep_10	2.8e-23
GPT	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
GPT	GOBP_Response_To_Extracellular_Stimulus	Human	Brain	rep_11	2.5e-12
GPT	GOBP_Response_To_Peptide	Human	Bladder	rep_2	2.3e-11
GPT	GOBP_Response_To_Peptide_Hormone	Human	Bladder	rep_2	2.9e-13
GPT	GOBP_Positive_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Bladder	rep_4	2.7e-04
GPT	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
GPT	GOBP_Response_To_Extracellular_Stimulus	Human	Liver	rep_1	1.7e-73
GPT	GOBP_Response_To_Hormone	Human	Liver	rep_1	3.0e-55
GPT	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
GPT	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
GPT	GOBP_Response_To_Extracellular_Stimulus	Human	Intestine	rep_liver2	8.9e-16
GPT	GOBP_Response_To_Hormone	Human	Intestine	rep_liver2	3.7e-39
GPT	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
GPT	GOBP_Carbohydrate_Biosynthetic_Process	Human	Intestine	A3	5.4e-08
GPT	GOBP_Carbohydrate_Metabolic_Process	Human	Intestine	A3	4.1e-08
GPT	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Intestine	A3	3.9e-07
GPT	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Intestine	A3	8.7e-19
GPT	GOBP_Cellular_Response_To_Insulin_Stimulus	Human	Intestine	A3	4.8e-16
GPT	GOBP_Cellular_Response_To_Peptide_Hormone_Stimulus	Human	Intestine	A3	4.0e-16
GPT	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
GPT	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
GPT	GOBP_Response_To_Insulin	Human	Intestine	A3	2.2e-15
GPT	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
GPT	GOBP_Alanine_Catabolic_Process	Human	Intestine	A8	1.1e-07
GPT	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Intestine	A8	7.0e-13
GPT	GOBP_Cellular_Amino_Acid_Biosynthetic_Process	Human	Intestine	A8	3.7e-12
GPT	GOBP_Cellular_Amino_Acid_Catabolic_Process	Human	Intestine	A8	2.5e-14
GPT	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Intestine	A8	5.3e-13
GPT	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
GPT	GOBP_Cellular_Response_To_Peptide	Human	Intestine	A8	2.9e-08
GPT	GOBP_Glucose_Metabolic_Process	Human	Intestine	A8	1.5e-21
GPT	GOBP_Monosaccharide_Biosynthetic_Process	Human	Intestine	A8	4.0e-16
GPT	GOBP_Monosaccharide_Metabolic_Process	Human	Intestine	A8	4.7e-24
GPT	GOBP_Organic_Acid_Biosynthetic_Process	Human	Intestine	A8	2.1e-08
GPT	GOBP_Organic_Acid_Catabolic_Process	Human	Intestine	A8	1.6e-12
GPT	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
GPT	GOBP_Positive_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Intestine	A8	1.5e-07
GPT	GOBP_Positive_Regulation_Of_Gluconeogenesis	Human	Intestine	A8	1.5e-21
GPT	GOBP_Positive_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Intestine	A8	1.8e-13
GPT	GOBP_Regulation_Of_Carbohydrate_Biosynthetic_Process	Human	Intestine	A8	3.0e-15
GPT	GOBP_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Intestine	A8	1.8e-17
GPT	GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_Process	Human	Intestine	A8	1.7e-16
GPT	GOBP_Regulation_Of_Gluconeogenesis	Human	Intestine	A8	1.3e-11
GPT	GOBP_Regulation_Of_Glucose_Metabolic_Process	Human	Intestine	A8	4.7e-21
GPT	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Intestine	A8	1.7e-14
GPT	GOBP_Response_To_Extracellular_Stimulus	Human	Intestine	A8	2.1e-23
GPT	GOBP_Response_To_Hormone	Human	Intestine	A8	2.3e-13
GPT	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
GPT	GOBP_Response_To_Peptide	Human	Intestine	A8	2.0e-09
GPT	GOBP_Response_To_Peptide_Hormone	Human	Intestine	A8	3.4e-09
GPT	GOBP_Response_To_Starvation	Human	Intestine	A8	6.6e-17
GPT	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
GPT	GOBP_Small_Molecule_Catabolic_Process	Human	Intestine	A8	2.2e-13
GPT	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
GPT	GOBP_Regulation_Of_Gluconeogenesis	Human	Pancreas	PDAC-B-st1	5.2e-05
GPT	GOBP_Regulation_Of_Glucose_Metabolic_Process	Human	Pancreas	PDAC-B-st1	8.4e-05
GPT	GOBP_Response_To_Starvation	Human	Pancreas	PDAC-B-st1	9.3e-06
GPT	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Pancreas	PDAC-A-st2	9.6e-05
GPT	GOBP_Positive_Regulation_Of_Cellular_Carbohydrate_Metabolic_Process	Human	Uterus	rep_1	1.9e-06
GPT	GOBP_Positive_Regulation_Of_Glucose_Metabolic_Process	Human	Uterus	rep_1	1.9e-06
GPT	GOBP_Alanine_Catabolic_Process	Human	Uterus	rep_5	1.4e-07
GPT	GOBP_Alpha_Amino_Acid_Catabolic_Process	Human	Uterus	rep_25	1.2e-11
GPT	GOBP_Monosaccharide_Biosynthetic_Process	Human	Uterus	rep_25	6.0e-11
GPT	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	1.6e-06
GPT	GOBP_Carbohydrate_Biosynthetic_Process	Human	Uterus	rep_26	3.3e-14
GPT	GOBP_Cellular_Amino_Acid_Catabolic_Process	Human	Uterus	rep_26	3.2e-12
GPT	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Uterus	rep_26	2.2e-06
GPT	GOBP_Glucose_Metabolic_Process	Human	Uterus	rep_26	1.0e-15
GPT	GOBP_Monosaccharide_Metabolic_Process	Human	Uterus	rep_26	2.7e-11
GPT	GOBP_Organic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	2.3e-06
GPT	GOBP_Organic_Acid_Catabolic_Process	Human	Uterus	rep_26	6.9e-09
GPT	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
GPT	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
GPT	GOBP_Positive_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Uterus	rep_26	7.6e-08
GPT	GOBP_Positive_Regulation_Of_Gluconeogenesis	Human	Uterus	rep_26	3.6e-09
GPT	GOBP_Positive_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	1.9e-11
GPT	GOBP_Regulation_Of_Carbohydrate_Biosynthetic_Process	Human	Uterus	rep_26	1.8e-14
GPT	GOBP_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Uterus	rep_26	7.1e-09
GPT	GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_Process	Human	Uterus	rep_26	5.9e-07
GPT	GOBP_Regulation_Of_Gluconeogenesis	Human	Uterus	rep_26	1.0e-12
GPT	GOBP_Regulation_Of_Glucose_Metabolic_Process	Human	Uterus	rep_26	8.7e-07
GPT	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	2.0e-14
GPT	GOBP_Response_To_Extracellular_Stimulus	Human	Uterus	rep_26	1.1e-14
GPT	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
GPT	GOBP_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	9.1e-13
GPT	GOBP_Positive_Regulation_Of_Cellular_Carbohydrate_Metabolic_Process	Human	Breast	rep_1	2.4e-05
GPT	GOBP_Positive_Regulation_Of_Gluconeogenesis	Human	Breast	rep_1	6.9e-18
GPT	GOBP_Positive_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Breast	rep_1	3.3e-210
GPT	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Breast	rep_1	2.1e-94
GPT	GOBP_Response_To_Insulin	Human	Breast	rep_1	5.1e-04
GPT	GOBP_Response_To_Peptide_Hormone	Human	Breast	rep_1	2.0e-36
GPT	GOBP_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	3.5e-10
GPT	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	9.4e-08
GPT	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Breast	rep_5	9.6e-12
GPT	GOBP_Cellular_Response_To_Insulin_Stimulus	Human	Breast	rep_5	2.2e-04
GPT	GOBP_Cellular_Response_To_Nitrogen_Compound	Human	Breast	rep_5	4.4e-13
GPT	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
GPT	GOBP_Cellular_Response_To_Peptide_Hormone_Stimulus	Human	Breast	rep_5	6.3e-04
GPT	GOBP_Glucose_Metabolic_Process	Human	Breast	rep_5	1.3e-09
GPT	GOBP_Monosaccharide_Metabolic_Process	Human	Breast	rep_5	2.9e-08
GPT	GOBP_Organic_Acid_Biosynthetic_Process	Human	Breast	rep_5	3.5e-09
GPT	GOBP_Positive_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	4.6e-09
GPT	GOBP_Positive_Regulation_Of_Glucose_Metabolic_Process	Human	Breast	rep_5	1.3e-09
GPT	GOBP_Regulation_Of_Gluconeogenesis	Human	Breast	rep_5	1.0e-05
GPT	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
GPT	GOBP_Response_To_Extracellular_Stimulus	Human	Breast	rep_5	2.9e-12
GPT	GOBP_Response_To_Hormone	Human	Breast	rep_5	2.9e-13
GPT	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
GPT	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
GPT	GOBP_Response_To_Peptide	Human	Breast	rep_5	1.2e-15
GPT	GOBP_Response_To_Starvation	Human	Breast	rep_5	6.9e-08
GPT	GOBP_Alpha_Amino_Acid_Catabolic_Process	Human	Breast	rep_6	2.6e-05
GPT	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.7e-08
GPT	GOBP_Carbohydrate_Biosynthetic_Process	Human	Breast	rep_6	2.3e-09
GPT	GOBP_Cellular_Amino_Acid_Catabolic_Process	Human	Breast	rep_6	1.6e-05
GPT	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.0e-10
GPT	GOBP_Cellular_Response_To_Peptide	Human	Breast	rep_6	8.4e-11
GPT	GOBP_Monosaccharide_Biosynthetic_Process	Human	Breast	rep_6	1.7e-09
GPT	GOBP_Organic_Acid_Catabolic_Process	Human	Breast	rep_6	1.5e-11
GPT	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
GPT	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
GPT	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
GPT	GOBP_Regulation_Of_Carbohydrate_Biosynthetic_Process	Human	Breast	rep_6	5.3e-09
GPT	GOBP_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Breast	rep_6	4.9e-04
GPT	GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_Process	Human	Breast	rep_6	3.9e-06
GPT	GOBP_Regulation_Of_Glucose_Metabolic_Process	Human	Breast	rep_6	3.0e-05
GPT	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
GPT	GOBP_Small_Molecule_Catabolic_Process	Human	Breast	rep_6	4.7e-07
GPT	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
GPT	GOBP_Positive_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Skin	P2_rep2	3.1e-09
GPT	GOBP_Alanine_Catabolic_Process	Human	Lung	rep_1	1.1e-13
GPT	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08

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GPT function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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GPT function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for GPT envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for GPT

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for GPT

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source