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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CCDC88B (spascer ID:283234)

Gene summary for CCDC88B

Gene summary

Gene information
	Species	Human
	Gene symbol	CCDC88B
	Gene ID	283234
	Gene name	coiled-coil domain containing 88B
	Synonyms	BRLZ\|CCDC88\|HKRP3\|gipie
	Cytomap	11q13.1
	Type of gene	protein-coding
	Description	coiled-coil domain-containing protein 88B78 kDa glucose-regulated protein [GRP78]-interacting protein induced by ER stressGRP78-interacting protein induced by ER stressbrain leucine zipper domain-containing proteinbrain leucine zipper proteincoiled-c
	Modification date	20220513
	UniProtAcc	A6NC98

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CCDC88B	GO:0005737	cytoplasm	21873635	Component
CCDC88B	GO:0005813	centrosome	21873635	Component
CCDC88B	GO:0008017	microtubule binding	21873635	Function
CCDC88B	GO:0030705	cytoskeleton-dependent intracellular transport	21873635	Process
CCDC88B	GO:0031122	cytoplasmic microtubule organization	21873635	Process
CCDC88B	GO:0051959	dynein light intermediate chain binding	21873635	Function

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Spatial pattern events for CCDC88B

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CCDC88B	Human	Bladder	rep_1	34385456	1.92e-07
CCDC88B	Human	Bladder	rep_2	34385456	1.13e-14
CCDC88B	Human	Intestine	rep_colon1	34417225	1.95e-15
CCDC88B	Human	Intestine	rep_colon4	34417225	1.14e-15
CCDC88B	Human	Liver	rep_liver2	34417225	6.98e-16
CCDC88B	Human	Intestine	A1	33406409	6.31e-15
CCDC88B	Human	Intestine	A2	33406409	7.00e-15
CCDC88B	Human	Breast	1160920F	34493872	1.48e-15
CCDC88B	Human	Breast	CID44971	34493872	9.65e-13
CCDC88B	Human	Breast	CID4535	34493872	1.11e-14
CCDC88B	Human	Skin	mel1_rep2	30154148	2.48e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_1_H&E
Bladder_rep_2_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver2_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E

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Spatial pattern pathway has CCDC88B envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Brain	rep_1	1.3e-60
CCDC88B	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Brain	rep_1	4.4e-07
CCDC88B	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
CCDC88B	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
CCDC88B	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
CCDC88B	GOBP_Cytokine_Production	Human	Brain	rep_4	4.1e-17
CCDC88B	GOBP_Defense_Response	Human	Brain	rep_4	2.2e-20
CCDC88B	GOBP_Defense_Response_To_Other_Organism	Human	Brain	rep_4	1.2e-64
CCDC88B	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Brain	rep_4	4.1e-17
CCDC88B	GOBP_Cytokine_Production	Human	Liver	rep_1	1.0e-70
CCDC88B	GOBP_Defense_Response	Human	Liver	rep_1	1.3e-59
CCDC88B	GOBP_Defense_Response_To_Other_Organism	Human	Liver	rep_1	4.3e-69
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Liver	rep_1	2.0e-49
CCDC88B	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Liver	rep_1	6.0e-76
CCDC88B	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Liver	rep_1	3.7e-85
CCDC88B	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
CCDC88B	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
CCDC88B	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	rep_colon2	2.9e-50
CCDC88B	GOBP_Cytokine_Production	Human	Intestine	rep_colon4	9.0e-12
CCDC88B	GOBP_Defense_Response	Human	Intestine	rep_colon4	2.5e-86
CCDC88B	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	rep_colon4	1.2e-82
CCDC88B	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	rep_colon4	1.9e-09
CCDC88B	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	rep_colon4	6.4e-48
CCDC88B	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
CCDC88B	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
CCDC88B	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
CCDC88B	GOBP_Biological_Adhesion	Human	Intestine	A3	6.7e-11
CCDC88B	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
CCDC88B	GOBP_Cell_Cell_Adhesion	Human	Intestine	A3	2.5e-07
CCDC88B	GOBP_Cytokine_Production	Human	Intestine	A3	8.9e-12
CCDC88B	GOBP_Defense_Response	Human	Intestine	A3	6.3e-13
CCDC88B	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
CCDC88B	GOBP_Leukocyte_Cell_Cell_Adhesion	Human	Intestine	A3	6.3e-09
CCDC88B	GOBP_Lymphocyte_Activation	Human	Intestine	A3	1.8e-09
CCDC88B	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
CCDC88B	GOBP_Microtubule_Cytoskeleton_Organization	Human	Intestine	A3	4.8e-11
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Activation	Human	Intestine	A3	6.6e-07
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Adhesion	Human	Intestine	A3	4.4e-10
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Intestine	A3	5.1e-10
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	3.5e-07
CCDC88B	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	A3	8.0e-16
CCDC88B	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	A3	3.7e-11
CCDC88B	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	A3	6.8e-15
CCDC88B	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Intestine	A3	4.0e-07
CCDC88B	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
CCDC88B	GOBP_Regulation_Of_Cell_Activation	Human	Intestine	A3	1.8e-08
CCDC88B	GOBP_Regulation_Of_Cell_Adhesion	Human	Intestine	A3	1.5e-10
CCDC88B	GOBP_Regulation_Of_Cell_Cell_Adhesion	Human	Intestine	A3	1.2e-07
CCDC88B	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
CCDC88B	GOBP_Regulation_Of_Lymphocyte_Activation	Human	Intestine	A3	4.0e-08
CCDC88B	GOBP_Regulation_Of_T_Cell_Activation	Human	Intestine	A3	9.9e-08
CCDC88B	GOBP_T_Cell_Activation	Human	Intestine	A3	1.2e-07
CCDC88B	GOBP_Defense_Response_To_Other_Organism	Human	Intestine	A8	5.3e-08
CCDC88B	GOBP_Leukocyte_Proliferation	Human	Intestine	A8	5.7e-12
CCDC88B	GOBP_Positive_Regulation_Of_Leukocyte_Proliferation	Human	Intestine	A8	1.3e-10
CCDC88B	GOBP_Positive_Regulation_Of_T_Cell_Proliferation	Human	Intestine	A8	8.6e-10
CCDC88B	GOBP_Regulation_Of_Leukocyte_Proliferation	Human	Intestine	A8	5.9e-11
CCDC88B	GOBP_Response_To_Protozoan	Human	Intestine	A8	4.4e-14
CCDC88B	GOBP_T_Cell_Proliferation	Human	Intestine	A8	2.0e-13
CCDC88B	GOBP_Defense_Response_To_Other_Organism	Human	Uterus	rep_4	2.0e-31
CCDC88B	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
CCDC88B	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
CCDC88B	GOBP_Defense_Response	Human	Uterus	rep_1	3.0e-06
CCDC88B	GOBP_Cytoplasmic_Microtubule_Organization	Human	Uterus	rep_26	7.5e-09
CCDC88B	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
CCDC88B	GOBP_Lymphocyte_Activation	Human	Uterus	rep_28	6.6e-07
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Uterus	rep_28	5.4e-06
CCDC88B	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Uterus	rep_28	9.7e-06
CCDC88B	GOBP_Positive_Regulation_Of_Leukocyte_Proliferation	Human	Uterus	rep_28	5.3e-06
CCDC88B	GOBP_Positive_Regulation_Of_T_Cell_Proliferation	Human	Uterus	rep_28	5.2e-07
CCDC88B	GOBP_Regulation_Of_Lymphocyte_Activation	Human	Uterus	rep_28	6.6e-07
CCDC88B	GOBP_Biological_Adhesion	Human	Uterus	rep_29	3.3e-06
CCDC88B	GOBP_Biological_Adhesion	Human	Breast	rep_1	4.0e-110
CCDC88B	GOBP_Cell_Cell_Adhesion	Human	Breast	rep_1	3.6e-45
CCDC88B	GOBP_Cytokine_Production	Human	Breast	rep_1	6.5e-12
CCDC88B	GOBP_Cytoskeleton_Organization	Human	Breast	rep_1	1.3e-22
CCDC88B	GOBP_Defense_Response	Human	Breast	rep_1	1.0e-09
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	9.2e-11
CCDC88B	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Breast	rep_1	6.5e-10
CCDC88B	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Breast	rep_1	7.3e-07
CCDC88B	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
CCDC88B	GOBP_Regulation_Of_Cell_Adhesion	Human	Breast	rep_1	1.7e-16
CCDC88B	GOBP_Response_To_Protozoan	Human	Breast	rep_1	2.1e-18
CCDC88B	GOBP_Supramolecular_Fiber_Organization	Human	Breast	rep_1	2.8e-72
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Breast	rep_2	2.3e-04
CCDC88B	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Breast	rep_2	5.9e-07
CCDC88B	GOBP_Cytoplasmic_Microtubule_Organization	Human	Breast	rep_6	2.7e-05
CCDC88B	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
CCDC88B	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
CCDC88B	GOBP_Microtubule_Cytoskeleton_Organization	Human	Breast	rep_6	1.9e-04
CCDC88B	GOBP_Cytoplasmic_Microtubule_Organization	Human	Skin	P5_rep1	3.9e-11
CCDC88B	GOBP_Cytoskeleton_Organization	Human	Skin	P9_rep3	3.1e-12
CCDC88B	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
CCDC88B	GOBP_Defense_Response	Human	Lung	rep_1	9.9e-12
CCDC88B	GOBP_Defense_Response_To_Other_Organism	Human	Lung	rep_1	1.5e-09
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Lung	rep_1	7.3e-07
CCDC88B	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	3.1e-08
CCDC88B	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
CCDC88B	GOBP_Biological_Adhesion	Human	Lung	rep_2	6.6e-07
CCDC88B	GOBP_Cell_Cell_Adhesion	Human	Lung	rep_2	5.3e-07
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Activation	Human	Lung	rep_2	1.0e-07
CCDC88B	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Lung	rep_2	8.2e-08
CCDC88B	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Lung	rep_2	4.4e-07

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CCDC88B function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CCDC88B function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CCDC88B envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CCDC88B

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CCDC88B

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CCDC88B	C0023343	Leprosy	1	CTD_human