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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: BCL9L (spascer ID:283149)

Gene summary for BCL9L

Gene summary

Gene information
	Species	Human
	Gene symbol	BCL9L
	Gene ID	283149
	Gene name	BCL9 like
	Synonyms	B9L\|BCL9-2\|DLNB11
	Cytomap	11q23.3
	Type of gene	protein-coding
	Description	B-cell CLL/lymphoma 9-like proteinB cell CLL/lymphoma 9 likeB-cell lymphoma 9-like proteinBCL9-like proteinnuclear co-factor of beta-catenin signallingprotein BCL9-2
	Modification date	20220513
	UniProtAcc	Q86UU0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
BCL9L	GO:0008013	beta-catenin binding	21873635	Function
BCL9L	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	21873635	Process
BCL9L	GO:0045944	positive regulation of transcription by RNA polymerase II	21873635	Process
BCL9L	GO:0060070	canonical Wnt signaling pathway	21873635	Process
BCL9L	GO:1990907	beta-catenin-TCF complex	21873635	Component

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Spatial pattern events for BCL9L

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
BCL9L	Human	Liver	rep_liver2	34417225	6.98e-16
BCL9L	Human	Uterus	rep_3	34857954	3.02e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver2_H&E
Uterus_rep_3_H&E

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Spatial pattern pathway has BCL9L envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
BCL9L	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Brain	rep_1	2.3e-68
BCL9L	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
BCL9L	GOBP_Cell_Morphogenesis	Human	Brain	rep_4	1.0e-14
BCL9L	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
BCL9L	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Brain	rep_4	4.1e-17
BCL9L	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
BCL9L	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Bladder	rep_2	1.3e-05
BCL9L	GOBP_Epithelial_To_Mesenchymal_Transition	Human	Bladder	rep_2	3.4e-12
BCL9L	GOBP_Mesenchymal_Cell_Differentiation	Human	Bladder	rep_2	2.7e-14
BCL9L	GOBP_Mesenchyme_Development	Human	Bladder	rep_2	1.0e-24
BCL9L	GOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Bladder	rep_2	2.4e-08
BCL9L	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Bladder	rep_2	2.6e-04
BCL9L	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Bladder	rep_2	6.7e-07
BCL9L	GOBP_Regulation_Of_Epithelial_To_Mesenchymal_Transition	Human	Bladder	rep_2	1.3e-17
BCL9L	GOBP_Response_To_Growth_Factor	Human	Bladder	rep_2	1.2e-08
BCL9L	GOBP_Response_To_Transforming_Growth_Factor_Beta	Human	Bladder	rep_2	1.5e-11
BCL9L	GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Bladder	rep_2	2.2e-29
BCL9L	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Bladder	rep_2	2.5e-23
BCL9L	GOBP_Cell_Morphogenesis	Human	Liver	rep_1	2.1e-52
BCL9L	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Liver	rep_1	8.8e-90
BCL9L	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Liver	rep_1	2.8e-53
BCL9L	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
BCL9L	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
BCL9L	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Liver	rep_1	1.0e-70
BCL9L	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
BCL9L	GOBP_Cell_Morphogenesis	Human	Intestine	rep_colon2	1.5e-57
BCL9L	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Intestine	rep_colon2	5.0e-29
BCL9L	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
BCL9L	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
BCL9L	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	rep_colon4	9.0e-12
BCL9L	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
BCL9L	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
BCL9L	GOBP_Cell_Cell_Signaling_By_Wnt	Human	Intestine	A3	3.1e-07
BCL9L	GOBP_Cell_Morphogenesis	Human	Intestine	A3	9.7e-08
BCL9L	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Human	Intestine	A3	7.0e-07
BCL9L	GOBP_Mesenchymal_Cell_Differentiation	Human	Intestine	A3	1.8e-07
BCL9L	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Intestine	A3	6.0e-11
BCL9L	GOBP_Negative_Regulation_Of_Signaling	Human	Intestine	A3	4.9e-15
BCL9L	GOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Intestine	A3	1.2e-21
BCL9L	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Intestine	A3	1.1e-12
BCL9L	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.6e-14
BCL9L	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
BCL9L	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
BCL9L	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
BCL9L	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
BCL9L	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	A3	4.8e-12
BCL9L	GOBP_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.7e-10
BCL9L	GOBP_Regulation_Of_Cell_Morphogenesis	Human	Intestine	A3	5.8e-11
BCL9L	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Intestine	A3	4.5e-10
BCL9L	GOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_Stimulus	Human	Intestine	A3	8.9e-16
BCL9L	GOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Intestine	A3	2.6e-13
BCL9L	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
BCL9L	GOBP_Epithelial_To_Mesenchymal_Transition	Human	Intestine	A8	3.1e-08
BCL9L	GOBP_Positive_Regulation_Of_Epithelial_To_Mesenchymal_Transition	Human	Intestine	A8	6.8e-07
BCL9L	GOBP_Response_To_Transforming_Growth_Factor_Beta	Human	Intestine	A8	1.1e-10
BCL9L	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Intestine	A8	1.4e-29
BCL9L	GOBP_Skeletal_Muscle_Organ_Development	Human	Intestine	A8	2.2e-39
BCL9L	GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Intestine	A8	5.8e-13
BCL9L	GOBP_Maintenance_Of_Cell_Number	Human	Pancreas	PDAC-B-st1	3.7e-06
BCL9L	GOBP_Negative_Regulation_Of_Signaling	Human	Pancreas	PDAC-B-st1	1.7e-05
BCL9L	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Pancreas	PDAC-B-st1	2.2e-05
BCL9L	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Pancreas	PDAC-B-st1	1.5e-05
BCL9L	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Uterus	rep_1	2.7e-07
BCL9L	GOBP_Skeletal_Muscle_Organ_Development	Human	Uterus	rep_25	7.4e-10
BCL9L	GOBP_Somatic_Stem_Cell_Population_Maintenance	Human	Uterus	rep_25	7.4e-09
BCL9L	GOBP_Cell_Cell_Signaling_By_Wnt	Human	Uterus	rep_26	5.5e-06
BCL9L	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Human	Uterus	rep_26	9.2e-08
BCL9L	GOBP_Muscle_Organ_Development	Human	Uterus	rep_26	6.5e-08
BCL9L	GOBP_Muscle_Tissue_Development	Human	Uterus	rep_26	1.2e-10
BCL9L	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_26	1.6e-09
BCL9L	GOBP_Positive_Regulation_Of_Epithelial_To_Mesenchymal_Transition	Human	Uterus	rep_26	2.9e-10
BCL9L	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Uterus	rep_26	3.3e-06
BCL9L	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Uterus	rep_29	1.2e-06
BCL9L	GOBP_Negative_Regulation_Of_Signaling	Human	Uterus	rep_29	5.3e-06
BCL9L	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
BCL9L	GOBP_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_29	2.8e-06
BCL9L	GOBP_Cell_Morphogenesis	Human	Breast	rep_1	5.7e-26
BCL9L	GOBP_Epithelial_To_Mesenchymal_Transition	Human	Breast	rep_1	2.2e-13
BCL9L	GOBP_Mesenchymal_Cell_Differentiation	Human	Breast	rep_1	3.1e-28
BCL9L	GOBP_Mesenchyme_Development	Human	Breast	rep_1	1.1e-38
BCL9L	GOBP_Muscle_Organ_Development	Human	Breast	rep_1	1.5e-42
BCL9L	GOBP_Muscle_Structure_Development	Human	Breast	rep_1	6.8e-61
BCL9L	GOBP_Muscle_Tissue_Development	Human	Breast	rep_1	1.0e-09
BCL9L	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Human	Breast	rep_1	2.4e-07
BCL9L	GOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Breast	rep_1	1.3e-07
BCL9L	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Breast	rep_1	4.6e-15
BCL9L	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	7.1e-96
BCL9L	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
BCL9L	GOBP_Positive_Regulation_Of_Epithelial_To_Mesenchymal_Transition	Human	Breast	rep_1	5.8e-10
BCL9L	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
BCL9L	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Breast	rep_1	4.6e-22
BCL9L	GOBP_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	2.5e-42
BCL9L	GOBP_Regulation_Of_Cell_Morphogenesis	Human	Breast	rep_1	5.0e-35
BCL9L	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Human	Breast	rep_1	8.3e-72
BCL9L	GOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_Stimulus	Human	Breast	rep_1	2.1e-15
BCL9L	GOBP_Regulation_Of_Epithelial_To_Mesenchymal_Transition	Human	Breast	rep_1	1.9e-08
BCL9L	GOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Breast	rep_1	9.9e-11
BCL9L	GOBP_Response_To_Growth_Factor	Human	Breast	rep_1	1.2e-13
BCL9L	GOBP_Response_To_Transforming_Growth_Factor_Beta	Human	Breast	rep_1	2.4e-65
BCL9L	GOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Breast	rep_1	4.6e-27
BCL9L	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Human	Breast	rep_5	4.6e-14
BCL9L	GOBP_Negative_Regulation_Of_Signaling	Human	Breast	rep_5	8.6e-14
BCL9L	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
BCL9L	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
BCL9L	GOBP_Skeletal_Muscle_Cell_Differentiation	Human	Breast	rep_5	4.2e-04
BCL9L	GOBP_Skeletal_Muscle_Organ_Development	Human	Breast	rep_5	5.2e-09
BCL9L	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Human	Breast	rep_5	4.5e-06
BCL9L	GOBP_Canonical_Wnt_Signaling_Pathway	Human	Breast	rep_6	6.4e-04
BCL9L	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
BCL9L	GOBP_Cell_Cell_Signaling_By_Wnt	Human	Breast	rep_6	4.2e-06
BCL9L	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Human	Breast	rep_6	1.5e-06
BCL9L	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
BCL9L	GOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_Pathway	Human	Skin	P2_rep2	3.3e-08
BCL9L	GOBP_Skeletal_Muscle_Organ_Development	Human	Skin	P5_rep1	8.8e-12
BCL9L	GOBP_Somatic_Stem_Cell_Population_Maintenance	Human	Skin	P10_rep1	6.2e-14
BCL9L	GOBP_Positive_Regulation_Of_Epithelial_To_Mesenchymal_Transition	Human	Skin	P10_rep2	3.3e-10

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BCL9L function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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BCL9L function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for BCL9L envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for BCL9L

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for BCL9L

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
BCL9L	C0266642	Situs ambiguus	1	GENOMICS_ENGLAND