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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: GPI (spascer ID:2821)

Gene summary for GPI

Gene summary

Gene information
	Species	Human
	Gene symbol	GPI
	Gene ID	2821
	Gene name	glucose-6-phosphate isomerase
	Synonyms	AMF\|GNPI\|NLK\|PGI\|PHI\|SA-36\|SA36
	Cytomap	19q13.11
	Type of gene	protein-coding
	Description	glucose-6-phosphate isomeraseautocrine motility factorhexose monophosphate isomerasehexosephosphate isomeraseneuroleukinoxoisomerasephosphoglucose isomerasephosphohexomutasephosphohexose isomerasephosphosaccharomutasesperm antigen-36
	Modification date	20220513
	UniProtAcc	P06744

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
GPI	GO:0004347	glucose-6-phosphate isomerase activity	21873635	Function
GPI	GO:0005829	cytosol	21873635	Component
GPI	GO:0006094	gluconeogenesis	21873635	Process
GPI	GO:0006096	glycolytic process	21873635	Process
GPI	GO:0048029	monosaccharide binding	21873635	Function
GPI	GO:0051156	glucose 6-phosphate metabolic process	21873635	Process

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Spatial pattern events for GPI

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
GPI	Human	Brain	rep_1	33558695	5.91e-08
GPI	Human	Brain	rep_3	33558695	1.52e-14
GPI	Human	Brain	rep_5	33558695	1.56e-08
GPI	Human	Brain	rep_9	33558695	3.01e-15
GPI	Human	Brain	rep_10	33558695	3.23e-15
GPI	Human	Brain	rep_11	33558695	3.36e-15
GPI	Human	Brain	rep_12	33558695	8.26e-14
GPI	Human	Intestine	rep_colon1	34417225	1.95e-15
GPI	Human	Intestine	rep_colon2	34417225	8.12e-16
GPI	Human	Intestine	rep_colon3	34417225	1.82e-15
GPI	Human	Intestine	rep_colon4	34417225	2.06e-15
GPI	Human	Liver	rep_liver1	34417225	1.08e-15
GPI	Human	Liver	rep_liver2	34417225	6.98e-16
GPI	Human	Liver	rep_liver4	34417225	7.71e-16
GPI	Human	Intestine	A1	33406409	1.30e-09
GPI	Human	Intestine	A2	33406409	3.85e-15
GPI	Human	Uterus	rep_1	34857954	5.13e-15
GPI	Human	Uterus	rep_3	34857954	1.66e-15
GPI	Human	Breast	A4	34650042	5.05e-06
GPI	Human	Breast	A6	34650042	8.69e-13
GPI	Human	Breast	1142243F	34493872	2.30e-15
GPI	Human	Breast	1160920F	34493872	7.83e-14
GPI	Human	Breast	CID4290	34493872	4.68e-15
GPI	Human	Breast	CID4465	34493872	7.83e-15
GPI	Human	Breast	CID44971	34493872	1.76e-15
GPI	Human	Heart	w6_s2	31835037	7.74e-06
GPI	Human	Heart	w6_s3	31835037	1.28e-03
GPI	Human	Heart	w6_s4	31835037	4.35e-05
GPI	Human	Heart	w6_s5	31835037	1.39e-04
GPI	Human	Lung	rep_1	35355018	1.10e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_1_H&E
Uterus_rep_3_H&E
Breast_A4_H&E
Breast_A6_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has GPI envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
GPI	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
GPI	GOBP_Humoral_Immune_Response	Human	Brain	rep_1	8.1e-16
GPI	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
GPI	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
GPI	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
GPI	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	2.8e-23
GPI	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Brain	rep_1	4.4e-07
GPI	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
GPI	GOBP_Positive_Regulation_Of_Locomotion	Human	Brain	rep_1	3.1e-68
GPI	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Brain	rep_1	6.9e-125
GPI	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Brain	rep_1	3.1e-68
GPI	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
GPI	GOBP_Ameboidal_Type_Cell_Migration	Human	Bladder	rep_2	2.7e-06
GPI	GOBP_Positive_Regulation_Of_Endothelial_Cell_Migration	Human	Bladder	rep_2	2.4e-05
GPI	GOBP_Atp_Metabolic_Process	Human	Bladder	rep_4	3.6e-11
GPI	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Bladder	rep_4	3.4e-12
GPI	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
GPI	GOBP_Humoral_Immune_Response	Human	Liver	rep_1	9.0e-62
GPI	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
GPI	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
GPI	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
GPI	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	1.0e-70
GPI	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Liver	rep_1	3.7e-85
GPI	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
GPI	GOBP_Positive_Regulation_Of_Locomotion	Human	Liver	rep_1	1.9e-71
GPI	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Liver	rep_1	3.1e-62
GPI	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Liver	rep_1	1.9e-71
GPI	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
GPI	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Intestine	rep_colon2	3.9e-21
GPI	GOBP_Humoral_Immune_Response	Human	Intestine	rep_colon4	1.3e-27
GPI	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
GPI	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
GPI	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	rep_colon4	6.4e-48
GPI	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
GPI	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
GPI	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
GPI	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
GPI	GOBP_Positive_Regulation_Of_Locomotion	Human	Intestine	rep_liver2	1.0e-64
GPI	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	rep_liver2	1.0e-64
GPI	GOBP_Atp_Metabolic_Process	Human	Intestine	A3	7.9e-14
GPI	GOBP_Carbohydrate_Biosynthetic_Process	Human	Intestine	A3	5.4e-08
GPI	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
GPI	GOBP_Carbohydrate_Metabolic_Process	Human	Intestine	A3	4.1e-08
GPI	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
GPI	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Intestine	A3	4.0e-14
GPI	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
GPI	GOBP_Exocytosis	Human	Intestine	A3	4.7e-10
GPI	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Intestine	A3	4.3e-14
GPI	GOBP_Glucose_Catabolic_Process	Human	Intestine	A3	2.0e-09
GPI	GOBP_Glycolytic_Process_Through_Fructose_6_Phosphate	Human	Intestine	A3	5.4e-13
GPI	GOBP_Humoral_Immune_Response	Human	Intestine	A3	1.4e-08
GPI	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
GPI	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
GPI	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
GPI	GOBP_Monosaccharide_Catabolic_Process	Human	Intestine	A3	6.4e-10
GPI	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Intestine	A3	9.9e-10
GPI	GOBP_Organophosphate_Metabolic_Process	Human	Intestine	A3	4.4e-13
GPI	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	A3	3.7e-11
GPI	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	A3	6.8e-15
GPI	GOBP_Purine_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.9e-07
GPI	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Intestine	A3	2.9e-09
GPI	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	A3	1.1e-09
GPI	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
GPI	GOBP_Secretion	Human	Intestine	A3	1.8e-13
GPI	GOBP_Carbohydrate_Catabolic_Process	Human	Intestine	A8	2.0e-14
GPI	GOBP_Glucose_6_Phosphate_Metabolic_Process	Human	Intestine	A8	5.6e-09
GPI	GOBP_Glucose_Metabolic_Process	Human	Intestine	A8	1.5e-21
GPI	GOBP_Immunoglobulin_Production	Human	Intestine	A8	4.8e-07
GPI	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
GPI	GOBP_Monosaccharide_Biosynthetic_Process	Human	Intestine	A8	4.0e-16
GPI	GOBP_Monosaccharide_Metabolic_Process	Human	Intestine	A8	4.7e-24
GPI	GOBP_Myeloid_Leukocyte_Activation	Human	Intestine	A8	3.8e-18
GPI	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Intestine	A8	8.5e-11
GPI	GOBP_Nad_Metabolic_Process	Human	Intestine	A8	3.9e-11
GPI	GOBP_Nadh_Metabolic_Process	Human	Intestine	A8	4.4e-14
GPI	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Human	Intestine	A8	5.4e-20
GPI	GOBP_Nucleotide_Phosphorylation	Human	Intestine	A8	1.5e-18
GPI	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
GPI	GOBP_Positive_Regulation_Of_Epithelial_Cell_Migration	Human	Intestine	A8	5.3e-08
GPI	GOBP_Positive_Regulation_Of_Immune_Effector_Process	Human	Intestine	A8	1.1e-14
GPI	GOBP_Positive_Regulation_Of_Immunoglobulin_Production	Human	Intestine	A8	3.4e-07
GPI	GOBP_Positive_Regulation_Of_Locomotion	Human	Intestine	A8	9.7e-07
GPI	GOBP_Positive_Regulation_Of_Production_Of_Molecular_Mediator_Of_Immune_Response	Human	Intestine	A8	9.0e-17
GPI	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Human	Intestine	A8	1.5e-10
GPI	GOBP_Pyruvate_Metabolic_Process	Human	Intestine	A8	1.4e-20
GPI	GOBP_Regulation_Of_Immune_Effector_Process	Human	Intestine	A8	2.4e-12
GPI	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
GPI	GOBP_Small_Molecule_Catabolic_Process	Human	Intestine	A8	2.2e-13
GPI	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
GPI	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Pancreas	PDAC-B-st1	1.2e-05
GPI	GOBP_Glucose_Catabolic_Process	Human	Pancreas	PDAC-B-st1	1.9e-05
GPI	GOBP_Glycolytic_Process_Through_Fructose_6_Phosphate	Human	Pancreas	PDAC-B-st1	1.9e-05
GPI	GOBP_Immunoglobulin_Production	Human	Pancreas	PDAC-B-st1	6.2e-05
GPI	GOBP_Nadh_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
GPI	GOBP_Positive_Regulation_Of_Endothelial_Cell_Migration	Human	Pancreas	PDAC-B-st1	9.3e-05
GPI	GOBP_Humoral_Immune_Response	Human	Uterus	rep_4	2.0e-31
GPI	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
GPI	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
GPI	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
GPI	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
GPI	GOBP_Glycolytic_Process_Through_Fructose_6_Phosphate	Human	Uterus	rep_25	3.4e-08
GPI	GOBP_Monosaccharide_Biosynthetic_Process	Human	Uterus	rep_25	6.0e-11
GPI	GOBP_Nad_Metabolic_Process	Human	Uterus	rep_25	7.2e-08
GPI	GOBP_Atp_Metabolic_Process	Human	Uterus	rep_26	3.2e-08
GPI	GOBP_Carbohydrate_Biosynthetic_Process	Human	Uterus	rep_26	3.3e-14
GPI	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Uterus	rep_26	1.5e-11
GPI	GOBP_Endothelial_Cell_Migration	Human	Uterus	rep_26	5.1e-09
GPI	GOBP_Exocytosis	Human	Uterus	rep_26	5.1e-10
GPI	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Uterus	rep_26	1.8e-06
GPI	GOBP_Glucose_Catabolic_Process	Human	Uterus	rep_26	1.3e-06
GPI	GOBP_Glucose_Metabolic_Process	Human	Uterus	rep_26	1.0e-15
GPI	GOBP_Monosaccharide_Catabolic_Process	Human	Uterus	rep_26	2.3e-10
GPI	GOBP_Monosaccharide_Metabolic_Process	Human	Uterus	rep_26	2.7e-11
GPI	GOBP_Myeloid_Leukocyte_Activation	Human	Uterus	rep_26	1.4e-11
GPI	GOBP_Nadh_Metabolic_Process	Human	Uterus	rep_26	5.2e-06
GPI	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	2.4e-06
GPI	GOBP_Nucleotide_Phosphorylation	Human	Uterus	rep_26	7.8e-08
GPI	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
GPI	GOBP_Positive_Regulation_Of_Endothelial_Cell_Migration	Human	Uterus	rep_26	1.1e-09
GPI	GOBP_Purine_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.0e-06
GPI	GOBP_Pyruvate_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
GPI	GOBP_Regulation_Of_Endothelial_Cell_Migration	Human	Uterus	rep_26	1.2e-07
GPI	GOBP_Regulation_Of_Epithelial_Cell_Migration	Human	Uterus	rep_26	2.7e-06
GPI	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
GPI	GOBP_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	9.1e-13
GPI	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
GPI	GOBP_Immunoglobulin_Production	Human	Uterus	rep_28	4.0e-09
GPI	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Uterus	rep_28	8.7e-06
GPI	GOBP_Positive_Regulation_Of_Immune_Effector_Process	Human	Uterus	rep_28	3.5e-07
GPI	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Human	Uterus	rep_28	8.8e-09
GPI	GOBP_Regulation_Of_Immune_Effector_Process	Human	Uterus	rep_28	5.1e-07
GPI	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Uterus	rep_29	1.7e-06
GPI	GOBP_Ameboidal_Type_Cell_Migration	Human	Breast	rep_1	6.7e-99
GPI	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
GPI	GOBP_Endothelial_Cell_Migration	Human	Breast	rep_1	8.0e-84
GPI	GOBP_Exocytosis	Human	Breast	rep_1	2.8e-29
GPI	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
GPI	GOBP_Myeloid_Leukocyte_Activation	Human	Breast	rep_1	2.2e-37
GPI	GOBP_Positive_Regulation_Of_Endothelial_Cell_Migration	Human	Breast	rep_1	8.4e-28
GPI	GOBP_Positive_Regulation_Of_Epithelial_Cell_Migration	Human	Breast	rep_1	1.3e-49
GPI	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Breast	rep_1	7.3e-07
GPI	GOBP_Positive_Regulation_Of_Locomotion	Human	Breast	rep_1	7.2e-115
GPI	GOBP_Positive_Regulation_Of_Production_Of_Molecular_Mediator_Of_Immune_Response	Human	Breast	rep_1	3.8e-14
GPI	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Breast	rep_1	3.7e-127
GPI	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Breast	rep_1	5.5e-21
GPI	GOBP_Regulation_Of_Endothelial_Cell_Migration	Human	Breast	rep_1	4.5e-06
GPI	GOBP_Regulation_Of_Epithelial_Cell_Migration	Human	Breast	rep_1	1.6e-54
GPI	GOBP_Regulation_Of_Production_Of_Molecular_Mediator_Of_Immune_Response	Human	Breast	rep_1	1.4e-21
GPI	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
GPI	GOBP_Tissue_Migration	Human	Breast	rep_1	7.3e-113
GPI	GOBP_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	3.5e-10
GPI	GOBP_Glucose_Catabolic_Process	Human	Breast	rep_5	3.2e-07
GPI	GOBP_Glucose_Metabolic_Process	Human	Breast	rep_5	1.3e-09
GPI	GOBP_Glycolytic_Process_Through_Fructose_6_Phosphate	Human	Breast	rep_5	1.7e-16
GPI	GOBP_Monosaccharide_Metabolic_Process	Human	Breast	rep_5	2.9e-08
GPI	GOBP_Atp_Metabolic_Process	Human	Breast	rep_6	1.3e-06
GPI	GOBP_Carbohydrate_Biosynthetic_Process	Human	Breast	rep_6	2.3e-09
GPI	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
GPI	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Breast	rep_6	7.1e-09
GPI	GOBP_Glucose_6_Phosphate_Metabolic_Process	Human	Breast	rep_6	7.5e-17
GPI	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
GPI	GOBP_Monosaccharide_Biosynthetic_Process	Human	Breast	rep_6	1.7e-09
GPI	GOBP_Monosaccharide_Catabolic_Process	Human	Breast	rep_6	8.1e-07
GPI	GOBP_Nad_Metabolic_Process	Human	Breast	rep_6	1.6e-14
GPI	GOBP_Nadh_Metabolic_Process	Human	Breast	rep_6	3.2e-09
GPI	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	1.7e-10
GPI	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Human	Breast	rep_6	4.5e-05
GPI	GOBP_Nucleotide_Phosphorylation	Human	Breast	rep_6	2.0e-05
GPI	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
GPI	GOBP_Organophosphate_Metabolic_Process	Human	Breast	rep_6	1.0e-12
GPI	GOBP_Purine_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	2.5e-09
GPI	GOBP_Pyruvate_Metabolic_Process	Human	Breast	rep_6	1.0e-04
GPI	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
GPI	GOBP_Small_Molecule_Catabolic_Process	Human	Breast	rep_6	4.7e-07
GPI	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
GPI	GOBP_Glucose_6_Phosphate_Metabolic_Process	Human	Skin	P2_rep2	9.4e-14
GPI	GOBP_Endothelial_Cell_Migration	Human	Skin	P5_rep2	2.0e-08
GPI	GOBP_Regulation_Of_Epithelial_Cell_Migration	Human	Skin	P5_rep2	3.3e-09
GPI	GOBP_Nad_Metabolic_Process	Human	Skin	P10_rep1	4.9e-08
GPI	GOBP_Glucose_Catabolic_Process	Human	Skin	P10_rep2	1.4e-17
GPI	GOBP_Glycolytic_Process_Through_Fructose_6_Phosphate	Human	Skin	P10_rep2	1.4e-18
GPI	GOBP_Monosaccharide_Catabolic_Process	Human	Skin	P10_rep2	7.1e-10
GPI	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Skin	P10_rep2	1.1e-22
GPI	GOBP_Nadh_Metabolic_Process	Human	Skin	P10_rep2	1.6e-08
GPI	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
GPI	GOBP_Humoral_Immune_Response	Human	Lung	rep_1	1.7e-10
GPI	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	3.1e-08
GPI	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
GPI	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Lung	rep_2	8.0e-10

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GPI function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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GPI function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for GPI envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for GPI

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
GPI	P06744	DB09130	Copper	Glucose-6-phosphate isomerase	SmallMoleculeDrug	approved\|investigational

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Related Diseases for GPI

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
GPI	C3150730	HEMOLYTIC ANEMIA, NONSPHEROCYTIC, DUE TO GLUCOSE PHOSPHATE ISOMERASE DEFICIENCY	10	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
GPI	C0002878	Anemia, Hemolytic	1	CTD_human
GPI	C0002879	Anemia, Hemolytic, Acquired	1	CTD_human
GPI	C0002889	Anemia, Microangiopathic	1	CTD_human
GPI	C0006142	Malignant neoplasm of breast	1	CTD_human
GPI	C0221021	Microangiopathic hemolytic anemia	1	CTD_human
GPI	C0678222	Breast Carcinoma	1	CTD_human
GPI	C1257931	Mammary Neoplasms, Human	1	CTD_human
GPI	C1458155	Mammary Neoplasms	1	CTD_human
GPI	C4704874	Mammary Carcinoma, Human	1	CTD_human