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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: GPD2 (spascer ID:2820)

Gene summary for GPD2

Gene summary

Gene information
	Species	Human
	Gene symbol	GPD2
	Gene ID	2820
	Gene name	glycerol-3-phosphate dehydrogenase 2
	Synonyms	GDH2\|GPDM\|mGDH\|mGPDH
	Cytomap	2q24.1
	Type of gene	protein-coding
	Description	glycerol-3-phosphate dehydrogenase, mitochondrialGPD-MGPDH-Mglycerol-3-phosphate dehydrogenase 2 (mitochondrial)mitochondrial glycerophosphate dehydrogenasemitohondrial glycerophosphate dehydrogenasemtGPDtesticular tissue protein Li 76
	Modification date	20220513
	UniProtAcc	P43304

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
GPD2	GO:0005739	mitochondrion	21873635	Component

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Spatial pattern events for GPD2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
GPD2	Human	Intestine	rep_colon4	34417225	2.06e-15
GPD2	Human	Liver	rep_liver1	34417225	1.89e-15
GPD2	Human	Liver	rep_liver2	34417225	6.98e-16
GPD2	Human	Intestine	A2	33406409	2.04e-07
GPD2	Human	Breast	CID4290	34493872	4.68e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Intestine_A2_H&E
Breast_CID4290_H&E

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Spatial pattern pathway has GPD2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
GPD2	GOBP_Cellular_Respiration	Human	Bladder	rep_4	2.0e-15
GPD2	GOBP_Electron_Transport_Chain	Human	Bladder	rep_4	1.0e-20
GPD2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Bladder	rep_4	1.5e-12
GPD2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Bladder	rep_4	3.4e-12
GPD2	GOBP_Respiratory_Electron_Transport_Chain	Human	Bladder	rep_4	4.7e-21
GPD2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
GPD2	GOBP_Carbohydrate_Metabolic_Process	Human	Intestine	A3	4.1e-08
GPD2	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Intestine	A3	3.9e-07
GPD2	GOBP_Cellular_Respiration	Human	Intestine	A3	6.2e-15
GPD2	GOBP_Electron_Transport_Chain	Human	Intestine	A3	1.4e-19
GPD2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Intestine	A3	2.5e-12
GPD2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Intestine	A3	4.3e-14
GPD2	GOBP_Organophosphate_Metabolic_Process	Human	Intestine	A3	4.4e-13
GPD2	GOBP_Respiratory_Electron_Transport_Chain	Human	Intestine	A3	7.5e-17
GPD2	GOBP_Alcohol_Catabolic_Process	Human	Intestine	A8	2.4e-10
GPD2	GOBP_Alditol_Catabolic_Process	Human	Intestine	A8	1.1e-10
GPD2	GOBP_Alditol_Metabolic_Process	Human	Intestine	A8	3.6e-15
GPD2	GOBP_Alditol_Phosphate_Metabolic_Process	Human	Intestine	A8	3.9e-21
GPD2	GOBP_Carbohydrate_Catabolic_Process	Human	Intestine	A8	2.0e-14
GPD2	GOBP_Cellular_Carbohydrate_Catabolic_Process	Human	Intestine	A8	2.1e-16
GPD2	GOBP_Cellular_Ketone_Metabolic_Process	Human	Intestine	A8	1.2e-11
GPD2	GOBP_Glycerol_3_Phosphate_Metabolic_Process	Human	Intestine	A8	5.6e-13
GPD2	GOBP_Nad_Metabolic_Process	Human	Intestine	A8	3.9e-11
GPD2	GOBP_Nadh_Metabolic_Process	Human	Intestine	A8	4.4e-14
GPD2	GOBP_Organic_Hydroxy_Compound_Catabolic_Process	Human	Intestine	A8	1.3e-13
GPD2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Intestine	A8	6.4e-10
GPD2	GOBP_Polyol_Catabolic_Process	Human	Intestine	A8	4.0e-22
GPD2	GOBP_Polyol_Metabolic_Process	Human	Intestine	A8	6.2e-14
GPD2	GOBP_Small_Molecule_Catabolic_Process	Human	Intestine	A8	2.2e-13
GPD2	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
GPD2	GOBP_Alcohol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
GPD2	GOBP_Nadh_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
GPD2	GOBP_Polyol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.8e-06
GPD2	GOBP_Alditol_Phosphate_Metabolic_Process	Human	Uterus	rep_25	4.8e-06
GPD2	GOBP_Nad_Metabolic_Process	Human	Uterus	rep_25	7.2e-08
GPD2	GOBP_Nadh_Oxidation	Human	Uterus	rep_25	1.1e-08
GPD2	GOBP_Alcohol_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
GPD2	GOBP_Alditol_Metabolic_Process	Human	Uterus	rep_26	6.9e-09
GPD2	GOBP_Cellular_Carbohydrate_Catabolic_Process	Human	Uterus	rep_26	5.7e-08
GPD2	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Uterus	rep_26	2.2e-06
GPD2	GOBP_Cellular_Ketone_Metabolic_Process	Human	Uterus	rep_26	3.2e-13
GPD2	GOBP_Cellular_Respiration	Human	Uterus	rep_26	3.7e-07
GPD2	GOBP_Electron_Transport_Chain	Human	Uterus	rep_26	1.9e-08
GPD2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Uterus	rep_26	7.2e-06
GPD2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Uterus	rep_26	1.8e-06
GPD2	GOBP_Glycerol_3_Phosphate_Metabolic_Process	Human	Uterus	rep_26	3.0e-08
GPD2	GOBP_Nadh_Metabolic_Process	Human	Uterus	rep_26	5.2e-06
GPD2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Uterus	rep_26	2.5e-08
GPD2	GOBP_Polyol_Catabolic_Process	Human	Uterus	rep_26	4.3e-11
GPD2	GOBP_Primary_Alcohol_Metabolic_Process	Human	Uterus	rep_26	2.6e-10
GPD2	GOBP_Respiratory_Electron_Transport_Chain	Human	Uterus	rep_26	2.1e-08
GPD2	GOBP_Small_Molecule_Catabolic_Process	Human	Uterus	rep_26	9.1e-13
GPD2	GOBP_Cellular_Ketone_Metabolic_Process	Human	Breast	rep_1	6.1e-19
GPD2	GOBP_Nadh_Oxidation	Human	Breast	rep_1	5.5e-04
GPD2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Breast	rep_1	7.3e-16
GPD2	GOBP_Polyol_Catabolic_Process	Human	Breast	rep_1	5.1e-04
GPD2	GOBP_Alditol_Phosphate_Metabolic_Process	Human	Breast	rep_5	2.2e-27
GPD2	GOBP_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	3.5e-10
GPD2	GOBP_Cellular_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	9.4e-08
GPD2	GOBP_Electron_Transport_Chain	Human	Breast	rep_5	6.2e-04
GPD2	GOBP_Glycerol_3_Phosphate_Metabolic_Process	Human	Breast	rep_5	2.6e-04
GPD2	GOBP_Respiratory_Electron_Transport_Chain	Human	Breast	rep_5	3.1e-04
GPD2	GOBP_Alcohol_Metabolic_Process	Human	Breast	rep_6	1.3e-04
GPD2	GOBP_Alditol_Catabolic_Process	Human	Breast	rep_6	8.7e-06
GPD2	GOBP_Alditol_Metabolic_Process	Human	Breast	rep_6	1.7e-09
GPD2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
GPD2	GOBP_Cellular_Carbohydrate_Catabolic_Process	Human	Breast	rep_6	1.0e-15
GPD2	GOBP_Cellular_Respiration	Human	Breast	rep_6	2.2e-06
GPD2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Breast	rep_6	5.2e-08
GPD2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Breast	rep_6	7.1e-09
GPD2	GOBP_Nad_Metabolic_Process	Human	Breast	rep_6	1.6e-14
GPD2	GOBP_Nadh_Metabolic_Process	Human	Breast	rep_6	3.2e-09
GPD2	GOBP_Organophosphate_Metabolic_Process	Human	Breast	rep_6	1.0e-12
GPD2	GOBP_Polyol_Metabolic_Process	Human	Breast	rep_6	2.9e-05
GPD2	GOBP_Primary_Alcohol_Metabolic_Process	Human	Breast	rep_6	2.0e-08
GPD2	GOBP_Small_Molecule_Catabolic_Process	Human	Breast	rep_6	4.7e-07
GPD2	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
GPD2	GOBP_Primary_Alcohol_Metabolic_Process	Human	Skin	P2_rep3	4.9e-08
GPD2	GOBP_Cellular_Carbohydrate_Catabolic_Process	Human	Skin	P10_rep1	8.0e-08
GPD2	GOBP_Nad_Metabolic_Process	Human	Skin	P10_rep1	4.9e-08
GPD2	GOBP_Alditol_Catabolic_Process	Human	Skin	P10_rep2	7.2e-08
GPD2	GOBP_Alditol_Metabolic_Process	Human	Skin	P10_rep2	1.3e-15
GPD2	GOBP_Alditol_Phosphate_Metabolic_Process	Human	Skin	P10_rep2	1.5e-19
GPD2	GOBP_Nadh_Metabolic_Process	Human	Skin	P10_rep2	1.6e-08
GPD2	GOBP_Cellular_Ketone_Metabolic_Process	Human	Lung	rep_2	2.1e-09

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GPD2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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GPD2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for GPD2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for GPD2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for GPD2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
GPD2	C0001787	Osteoporosis, Age-Related	1	CTD_human
GPD2	C0002152	Alloxan Diabetes	1	CTD_human
GPD2	C0011853	Diabetes Mellitus, Experimental	1	CTD_human
GPD2	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	1	CTD_human
GPD2	C0029456	Osteoporosis	1	CTD_human
GPD2	C0029459	Osteoporosis, Senile	1	CTD_human
GPD2	C0038433	Streptozotocin Diabetes	1	CTD_human
GPD2	C0268583	Methylmalonic acidemia	1	CTD_human
GPD2	C0751406	Post-Traumatic Osteoporosis	1	CTD_human
GPD2	C1855119	Methylmalonic aciduria	1	CTD_human