|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: GNB2 (spascer ID:2783) |
Gene summary for GNB2 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | GNB2 | Gene ID | 2783 |
| Gene name | G protein subunit beta 2 |
| Synonyms | HG2C1|SSS4|SSS4; NEDHYDF |
| Cytomap | 7q22.1 |
| Type of gene | protein-coding |
| Description | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2G protein, beta-2 subunitepididymis secretory sperm binding proteing protein subunit beta-2guanine nucleotide binding protein (G protein), beta polypeptide 2guanine nucleotide-binding pr |
| Modification date | 20220513 |
| UniProtAcc | P62879 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| GNB2 | GO:0005737 | cytoplasm | 21873635 | Component |
| GNB2 | GO:0005834 | heterotrimeric G-protein complex | 21873635 | Component |
| GNB2 | GO:0007186 | G protein-coupled receptor signaling pathway | 21873635 | Process |
| GNB2 | GO:0030159 | signaling receptor complex adaptor activity | 21873635 | Function |
Top |
Spatial pattern events for GNB2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| GNB2 | Human | Bladder | rep_3 | 34385456 | 2.56e-06 |
| GNB2 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| GNB2 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| GNB2 | Human | Intestine | rep_colon3 | 34417225 | 1.01e-15 |
| GNB2 | Human | Intestine | rep_colon4 | 34417225 | 3.94e-15 |
| GNB2 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| GNB2 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| GNB2 | Human | Liver | rep_liver3 | 34417225 | 3.51e-15 |
| GNB2 | Human | Liver | rep_liver4 | 34417225 | 3.33e-13 |
| GNB2 | Human | Intestine | A1 | 33406409 | 6.31e-15 |
| GNB2 | Human | Intestine | A2 | 33406409 | 2.47e-15 |
| GNB2 | Human | Uterus | rep_2 | 34857954 | 4.63e-15 |
| GNB2 | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| GNB2 | Human | Breast | D1 | 34650042 | 2.29e-08 |
| GNB2 | Human | Breast | D2 | 34650042 | 7.61e-12 |
| GNB2 | Human | Breast | D4 | 34650042 | 6.74e-09 |
| GNB2 | Human | Breast | D5 | 34650042 | 1.29e-10 |
| GNB2 | Human | Breast | 1142243F | 34493872 | 8.28e-08 |
| GNB2 | Human | Breast | 1160920F | 34493872 | 1.48e-15 |
| GNB2 | Human | Breast | CID4290 | 34493872 | 8.08e-15 |
| GNB2 | Human | Breast | CID4465 | 34493872 | 7.83e-15 |
| GNB2 | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| GNB2 | Human | Heart | w9_s5 | 31835037 | 5.65e-04 |
| GNB2 | Human | Lung | rep_1 | 35355018 | 7.40e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Bladder_rep_3_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon3_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver3_H&E  |  |
Liver_rep_liver4_H&E  |  |
Intestine_A1_H&E  |  |
Intestine_A2_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_D1_H&E  |  |
Breast_D2_H&E  |  |
Breast_D4_H&E  |  |
Breast_D5_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4290_H&E  |  |
Breast_CID4465_H&E  |  |
Breast_CID44971_H&E  |  |
Lung_rep_1_H&E  |  |
Top |
Spatial pattern pathway has GNB2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| GNB2 | GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway | Human | Brain | rep_1 | 2.8e-23 |
| GNB2 | GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway | Human | Liver | rep_1 | 1.0e-70 |
| GNB2 | GOBP_Protein_Folding | Human | Intestine | A3 | 3.4e-14 |
| GNB2 | GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway | Human | Intestine | A8 | 1.4e-14 |
| GNB2 | GOBP_Protein_Folding | Human | Pancreas | PDAC-B-st1 | 1.2e-05 |
| GNB2 | GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway | Human | Uterus | rep_26 | 3.5e-06 |
| GNB2 | GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway | Human | Breast | rep_1 | 3.6e-09 |
| GNB2 | GOBP_Protein_Folding | Human | Breast | rep_5 | 6.0e-09 |
| GNB2 | GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway | Human | Lung | rep_2 | 4.8e-08 |
Top |
GNB2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
GNB2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for GNB2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for GNB2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for GNB2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
