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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: FAM162A (spascer ID:26355)

Gene summary for FAM162A

Gene summary

Gene information
	Species	Human
	Gene symbol	FAM162A
	Gene ID	26355
	Gene name	family with sequence similarity 162 member A
	Synonyms	C3orf28\|E2IG5\|HGTD-P
	Cytomap	3q21.1
	Type of gene	protein-coding
	Description	protein FAM162AE2-induced gene 5 proteinHIF-1 alpha-responsive proapoptotic moleculegrowth and transformation-dependent protein
	Modification date	20220513
	UniProtAcc	Q96A26

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
FAM162A	GO:0005739	mitochondrion	21873635	Component
FAM162A	GO:0051402	neuron apoptotic process	21873635	Process
FAM162A	GO:0071456	cellular response to hypoxia	21873635	Process
FAM162A	GO:0090200	positive regulation of release of cytochrome c from mitochondria	21873635	Process

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Spatial pattern events for FAM162A

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
FAM162A	Human	Intestine	rep_colon1	34417225	1.95e-15
FAM162A	Human	Intestine	rep_colon2	34417225	8.12e-16
FAM162A	Human	Intestine	rep_colon4	34417225	1.14e-15
FAM162A	Human	Liver	rep_liver1	34417225	1.08e-15
FAM162A	Human	Liver	rep_liver2	34417225	6.98e-16
FAM162A	Human	Liver	rep_liver4	34417225	9.93e-09
FAM162A	Human	Intestine	A1	33406409	2.09e-15
FAM162A	Human	Intestine	A2	33406409	2.47e-15
FAM162A	Human	Uterus	rep_3	34857954	1.76e-07
FAM162A	Human	Breast	1142243F	34493872	2.67e-09
FAM162A	Human	Breast	1160920F	34493872	1.48e-15
FAM162A	Human	Heart	w6_s4	31835037	1.19e-06
FAM162A	Human	Heart	w6_s6	31835037	8.86e-03
FAM162A	Human	Skin	P2_rep1	32946785	8.65e-15
FAM162A	Human	Skin	P2_rep2	32946785	7.97e-12
FAM162A	Human	Skin	P2_rep3	32946785	2.27e-13
FAM162A	Human	Lung	rep_1	35355018	4.62e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_3_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Skin_P2_rep3_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has FAM162A envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
FAM162A	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
FAM162A	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
FAM162A	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
FAM162A	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
FAM162A	GOBP_Positive_Regulation_Of_Proteolysis	Human	Brain	rep_1	1.2e-161
FAM162A	GOBP_Regulation_Of_Proteolysis	Human	Brain	rep_1	4.4e-07
FAM162A	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
FAM162A	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
FAM162A	GOBP_Regulation_Of_Peptidase_Activity	Human	Brain	rep_4	4.1e-17
FAM162A	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
FAM162A	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
FAM162A	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
FAM162A	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
FAM162A	GOBP_Positive_Regulation_Of_Proteolysis	Human	Liver	rep_1	2.0e-70
FAM162A	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
FAM162A	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
FAM162A	GOBP_Regulation_Of_Peptidase_Activity	Human	Liver	rep_1	6.0e-76
FAM162A	GOBP_Regulation_Of_Proteolysis	Human	Liver	rep_1	1.1e-67
FAM162A	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
FAM162A	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
FAM162A	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
FAM162A	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	rep_colon2	1.6e-21
FAM162A	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
FAM162A	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
FAM162A	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
FAM162A	GOBP_Regulation_Of_Peptidase_Activity	Human	Intestine	rep_colon4	1.9e-09
FAM162A	GOBP_Regulation_Of_Proteolysis	Human	Intestine	rep_colon4	1.2e-51
FAM162A	GOBP_Activation_Of_Cysteine_Type_Endopeptidase_Activity_Involved_In_Apoptotic_Process	Human	Intestine	A3	2.9e-13
FAM162A	GOBP_Apoptotic_Mitochondrial_Changes	Human	Intestine	A3	1.6e-16
FAM162A	GOBP_Apoptotic_Signaling_Pathway	Human	Intestine	A3	7.0e-12
FAM162A	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Intestine	A3	2.0e-11
FAM162A	GOBP_Mitochondrion_Organization	Human	Intestine	A3	2.3e-19
FAM162A	GOBP_Neuron_Apoptotic_Process	Human	Intestine	A3	7.8e-11
FAM162A	GOBP_Neuron_Death	Human	Intestine	A3	2.4e-14
FAM162A	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
FAM162A	GOBP_Positive_Regulation_Of_Cell_Death	Human	Intestine	A3	4.5e-11
FAM162A	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
FAM162A	GOBP_Positive_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Intestine	A3	3.1e-08
FAM162A	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
FAM162A	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
FAM162A	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.7e-13
FAM162A	GOBP_Positive_Regulation_Of_Peptidase_Activity	Human	Intestine	A3	2.8e-12
FAM162A	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
FAM162A	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	A3	5.2e-21
FAM162A	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
FAM162A	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
FAM162A	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Intestine	A3	2.9e-10
FAM162A	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
FAM162A	GOBP_Regulation_Of_Mitochondrion_Organization	Human	Intestine	A3	1.6e-17
FAM162A	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
FAM162A	GOBP_Regulation_Of_Peptidase_Activity	Human	Intestine	A3	9.8e-13
FAM162A	GOBP_Regulation_Of_Proteolysis	Human	Intestine	A3	9.5e-13
FAM162A	GOBP_Regulation_Of_Release_Of_Cytochrome_C_From_Mitochondria	Human	Intestine	A3	6.1e-09
FAM162A	GOBP_Release_Of_Cytochrome_C_From_Mitochondria	Human	Intestine	A3	2.6e-09
FAM162A	GOBP_Response_To_Abiotic_Stimulus	Human	Intestine	A3	5.3e-18
FAM162A	GOBP_Response_To_Oxygen_Levels	Human	Intestine	A3	7.3e-15
FAM162A	GOBP_Positive_Regulation_Of_Release_Of_Cytochrome_C_From_Mitochondria	Human	Intestine	A8	1.8e-10
FAM162A	GOBP_Neuron_Apoptotic_Process	Human	Uterus	rep_26	4.5e-12
FAM162A	GOBP_Neuron_Death	Human	Uterus	rep_26	4.0e-13
FAM162A	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Uterus	rep_26	1.2e-06
FAM162A	GOBP_Regulation_Of_Proteolysis	Human	Uterus	rep_26	2.1e-07
FAM162A	GOBP_Release_Of_Cytochrome_C_From_Mitochondria	Human	Uterus	rep_27	1.5e-06
FAM162A	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
FAM162A	GOBP_Regulation_Of_Peptidase_Activity	Human	Uterus	rep_29	1.4e-10
FAM162A	GOBP_Apoptotic_Mitochondrial_Changes	Human	Breast	rep_1	9.3e-30
FAM162A	GOBP_Positive_Regulation_Of_Cell_Death	Human	Breast	rep_1	2.2e-15
FAM162A	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
FAM162A	GOBP_Positive_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Breast	rep_1	3.7e-11
FAM162A	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
FAM162A	GOBP_Positive_Regulation_Of_Peptidase_Activity	Human	Breast	rep_1	5.6e-24
FAM162A	GOBP_Positive_Regulation_Of_Proteolysis	Human	Breast	rep_1	1.7e-07
FAM162A	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Breast	rep_1	3.8e-05
FAM162A	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
FAM162A	GOBP_Regulation_Of_Peptidase_Activity	Human	Breast	rep_1	2.2e-33
FAM162A	GOBP_Regulation_Of_Proteolysis	Human	Breast	rep_1	6.4e-05
FAM162A	GOBP_Release_Of_Cytochrome_C_From_Mitochondria	Human	Breast	rep_1	2.9e-49
FAM162A	GOBP_Response_To_Abiotic_Stimulus	Human	Breast	rep_1	2.6e-19
FAM162A	GOBP_Response_To_Oxygen_Levels	Human	Breast	rep_1	6.1e-99
FAM162A	GOBP_Activation_Of_Cysteine_Type_Endopeptidase_Activity_Involved_In_Apoptotic_Process	Human	Breast	rep_5	4.6e-05
FAM162A	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Breast	rep_5	4.9e-11
FAM162A	GOBP_Neuron_Death	Human	Breast	rep_5	6.5e-07
FAM162A	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
FAM162A	GOBP_Positive_Regulation_Of_Mitochondrion_Organization	Human	Breast	rep_5	1.3e-04
FAM162A	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
FAM162A	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
FAM162A	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
FAM162A	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
FAM162A	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
FAM162A	GOBP_Regulation_Of_Release_Of_Cytochrome_C_From_Mitochondria	Human	Breast	rep_5	3.2e-09
FAM162A	GOBP_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	4.8e-09
FAM162A	GOBP_Mitochondrion_Organization	Human	Breast	rep_6	2.0e-05
FAM162A	GOBP_Neuron_Apoptotic_Process	Human	Breast	rep_6	1.3e-06
FAM162A	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Breast	rep_6	7.3e-09
FAM162A	GOBP_Positive_Regulation_Of_Release_Of_Cytochrome_C_From_Mitochondria	Human	Breast	rep_6	1.2e-06
FAM162A	GOBP_Regulation_Of_Mitochondrion_Organization	Human	Breast	rep_6	1.3e-06
FAM162A	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Skin	P5_rep3	4.1e-08
FAM162A	GOBP_Cellular_Response_To_Oxygen_Levels	Human	Lung	rep_1	2.8e-10
FAM162A	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Lung	rep_1	9.0e-08
FAM162A	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
FAM162A	GOBP_Regulation_Of_Peptidase_Activity	Human	Lung	rep_1	4.6e-11
FAM162A	GOBP_Regulation_Of_Proteolysis	Human	Lung	rep_1	3.2e-08
FAM162A	GOBP_Neuron_Apoptotic_Process	Human	Lung	rep_2	7.1e-08
FAM162A	GOBP_Neuron_Death	Human	Lung	rep_2	3.5e-08
FAM162A	GOBP_Positive_Regulation_Of_Cell_Death	Human	Lung	rep_2	3.0e-07
FAM162A	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07

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FAM162A function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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FAM162A function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for FAM162A envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for FAM162A

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for FAM162A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source