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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ERAL1 (spascer ID:26284)

Gene summary for ERAL1

Gene summary

Gene information
	Species	Human
	Gene symbol	ERAL1
	Gene ID	26284
	Gene name	Era like 12S mitochondrial rRNA chaperone 1
	Synonyms	CEGA\|ERA\|ERA-W\|ERAL1A\|ERAL1B\|H-ERA\|HERA-A\|HERA-B\|PRLTS6
	Cytomap	17q11.2
	Type of gene	protein-coding
	Description	GTPase Era, mitochondrialERA-like protein 1Era G-protein-like 1GTP-binding protein era homologGTPase, human homolog of E. coli essential cell cycle protein Eraconserved ERA-like GTPaseera (E. coli G-protein homolog)-like 1
	Modification date	20220513
	UniProtAcc	O75616

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ERAL1	GO:0000028	ribosomal small subunit assembly	21873635	Process
ERAL1	GO:0005759	mitochondrial matrix	21873635	Component
ERAL1	GO:0019843	rRNA binding	21873635	Function
ERAL1	GO:0043024	ribosomal small subunit binding	21873635	Function

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Spatial pattern events for ERAL1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ERAL1	Human	Liver	rep_liver1	34417225	1.08e-15
ERAL1	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has ERAL1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ERAL1	GOBP_Amide_Biosynthetic_Process	Human	Intestine	A1	6.4e-07
ERAL1	GOBP_Peptide_Biosynthetic_Process	Human	Intestine	A1	4.6e-10
ERAL1	GOBP_Ribosomal_Small_Subunit_Assembly	Human	Intestine	A1	3.5e-11
ERAL1	GOBP_Ribosomal_Small_Subunit_Biogenesis	Human	Intestine	A1	3.0e-16
ERAL1	GOBP_Ribosome_Assembly	Human	Intestine	A1	2.8e-16
ERAL1	GOBP_Ribosome_Biogenesis	Human	Intestine	A1	6.5e-08
ERAL1	GOBP_Translational_Elongation	Human	Intestine	A1	6.7e-08
ERAL1	GOBP_Translational_Termination	Human	Intestine	A1	3.9e-07
ERAL1	GOBP_Cellular_Component_Disassembly	Human	Intestine	A3	1.0e-14
ERAL1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Human	Intestine	A3	1.6e-07
ERAL1	GOBP_Mitochondrial_Gene_Expression	Human	Intestine	A8	1.4e-08
ERAL1	GOBP_Mitochondrial_Translation	Human	Intestine	A8	1.7e-08
ERAL1	GOBP_Mitochondrial_Translation	Human	Pancreas	PDAC-B-st1	5.1e-05
ERAL1	GOBP_Ribosomal_Small_Subunit_Assembly	Human	Pancreas	PDAC-A-st2	2.0e-05
ERAL1	GOBP_Ribosomal_Small_Subunit_Biogenesis	Human	Uterus	rep_1	3.0e-06
ERAL1	GOBP_Ribosome_Biogenesis	Human	Uterus	rep_1	9.5e-06
ERAL1	GOBP_Translational_Termination	Human	Uterus	rep_1	5.2e-09
ERAL1	GOBP_Mitochondrial_Translation	Human	Uterus	rep_25	3.6e-06
ERAL1	GOBP_Ribosomal_Small_Subunit_Assembly	Human	Uterus	rep_25	3.0e-14
ERAL1	GOBP_Translational_Elongation	Human	Uterus	rep_25	9.9e-08
ERAL1	GOBP_Cellular_Component_Disassembly	Human	Uterus	rep_26	2.7e-06
ERAL1	GOBP_Mitochondrial_Gene_Expression	Human	Uterus	rep_26	1.3e-15
ERAL1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Human	Uterus	rep_26	4.6e-06
ERAL1	GOBP_Ribosome_Assembly	Human	Uterus	rep_26	6.3e-19
ERAL1	GOBP_Translational_Termination	Human	Breast	rep_1	7.0e-06
ERAL1	GOBP_Cellular_Component_Disassembly	Human	Breast	rep_5	2.0e-06
ERAL1	GOBP_Amide_Biosynthetic_Process	Human	Breast	rep_6	8.7e-05
ERAL1	GOBP_Cellular_Amide_Metabolic_Process	Human	Breast	rep_6	5.6e-05
ERAL1	GOBP_Mitochondrial_Gene_Expression	Human	Breast	rep_6	9.9e-07
ERAL1	GOBP_Mitochondrial_Translation	Human	Breast	rep_6	1.3e-06
ERAL1	GOBP_Organelle_Assembly	Human	Breast	rep_6	2.3e-07
ERAL1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
ERAL1	GOBP_Peptide_Biosynthetic_Process	Human	Breast	rep_6	1.6e-05
ERAL1	GOBP_Peptide_Metabolic_Process	Human	Breast	rep_6	8.7e-05
ERAL1	GOBP_Protein_Containing_Complex_Disassembly	Human	Breast	rep_6	1.0e-13
ERAL1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Human	Breast	rep_6	1.3e-07
ERAL1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Human	Breast	rep_6	1.4e-08
ERAL1	GOBP_Ribosomal_Small_Subunit_Assembly	Human	Breast	rep_6	2.6e-06
ERAL1	GOBP_Ribosomal_Small_Subunit_Biogenesis	Human	Breast	rep_6	2.8e-07
ERAL1	GOBP_Ribosome_Assembly	Human	Breast	rep_6	7.2e-08
ERAL1	GOBP_Ribosome_Biogenesis	Human	Breast	rep_6	2.0e-06
ERAL1	GOBP_Translational_Termination	Human	Skin	P10_rep1	6.7e-10
ERAL1	GOBP_Cellular_Component_Disassembly	Human	Lung	rep_2	5.6e-07

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ERAL1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ERAL1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ERAL1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ERAL1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ERAL1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
ERAL1	C0685838	Gonadal dysgenesis XX type deafness	1	ORPHANET
ERAL1	C4479656	PERRAULT SYNDROME 6	1	GENOMICS_ENGLAND;UNIPROT