Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: TIPRL (spascer ID:261726)

Gene summary for TIPRL

Gene summary

Gene information
	Species	Human
	Gene symbol	TIPRL
	Gene ID	261726
	Gene name	TOR signaling pathway regulator
	Synonyms	TIP\|TIP41\|TIPRL1
	Cytomap	1q24.2
	Type of gene	protein-coding
	Description	TIP41-like proteinTIP41, TOR signaling pathway regulator-likeputative MAPK-activating protein PM10type 2A-interacting protein
	Modification date	20220513
	UniProtAcc	O75663

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
TIPRL	GO:0005829	cytosol	21873635	Component
TIPRL	GO:0031929	TOR signaling	21873635	Process
TIPRL	GO:0043666	regulation of phosphoprotein phosphatase activity	21873635	Process

Top

Spatial pattern events for TIPRL

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
TIPRL	Human	Liver	rep_liver2	34417225	6.98e-16
TIPRL	Human	Uterus	rep_3	34857954	9.77e-08
TIPRL	Human	Breast	1142243F	34493872	1.04e-07
TIPRL	Human	Breast	1160920F	34493872	3.47e-14
TIPRL	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver2_H&E
Uterus_rep_3_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E

Top

Spatial pattern pathway has TIPRL envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
TIPRL	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Brain	rep_1	7.4e-34
TIPRL	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	7.4e-34
TIPRL	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	7.4e-34
TIPRL	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
TIPRL	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
TIPRL	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Liver	rep_1	1.5e-73
TIPRL	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.0e-70
TIPRL	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
TIPRL	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
TIPRL	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
TIPRL	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
TIPRL	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
TIPRL	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	6.6e-16
TIPRL	GOBP_Dephosphorylation	Human	Intestine	A3	3.1e-14
TIPRL	GOBP_Negative_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	3.0e-12
TIPRL	GOBP_Negative_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	3.6e-12
TIPRL	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	7.8e-11
TIPRL	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	3.2e-14
TIPRL	GOBP_Protein_Dephosphorylation	Human	Intestine	A3	1.0e-10
TIPRL	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
TIPRL	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
TIPRL	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	1.5e-11
TIPRL	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
TIPRL	GOBP_Tor_Signaling	Human	Intestine	A3	5.1e-07
TIPRL	GOBP_Negative_Regulation_Of_Cell_Cycle	Human	Intestine	A8	3.1e-14
TIPRL	GOBP_Negative_Regulation_Of_Dephosphorylation	Human	Intestine	A8	2.4e-14
TIPRL	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Human	Intestine	A8	2.1e-14
TIPRL	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Intestine	A8	4.6e-12
TIPRL	GOBP_Negative_Regulation_Of_Protein_Dephosphorylation	Human	Intestine	A8	7.9e-15
TIPRL	GOBP_Regulation_Of_Dephosphorylation	Human	Intestine	A8	4.6e-14
TIPRL	GOBP_Regulation_Of_Phosphatase_Activity	Human	Intestine	A8	1.7e-11
TIPRL	GOBP_Regulation_Of_Phosphoprotein_Phosphatase_Activity	Human	Intestine	A8	6.2e-13
TIPRL	GOBP_Regulation_Of_Protein_Dephosphorylation	Human	Intestine	A8	1.0e-09
TIPRL	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_26	2.4e-07
TIPRL	GOBP_Negative_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	1.0e-08
TIPRL	GOBP_Negative_Regulation_Of_Dephosphorylation	Human	Uterus	rep_26	5.0e-09
TIPRL	GOBP_Negative_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_26	1.2e-08
TIPRL	GOBP_Negative_Regulation_Of_Protein_Dephosphorylation	Human	Uterus	rep_26	3.0e-06
TIPRL	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Human	Uterus	rep_26	2.3e-14
TIPRL	GOBP_Negative_Regulation_Of_Catalytic_Activity	Human	Uterus	rep_29	4.3e-12
TIPRL	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	2.9e-08
TIPRL	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Uterus	rep_29	1.6e-12
TIPRL	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
TIPRL	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_29	2.8e-06
TIPRL	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Breast	rep_1	7.1e-11
TIPRL	GOBP_Negative_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_1	2.4e-07
TIPRL	GOBP_Negative_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	3.6e-05
TIPRL	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	4.3e-05
TIPRL	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
TIPRL	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
TIPRL	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	2.5e-06
TIPRL	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
TIPRL	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
TIPRL	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	6.0e-06
TIPRL	GOBP_Dephosphorylation	Human	Breast	rep_6	2.8e-05
TIPRL	GOBP_Negative_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	5.3e-11
TIPRL	GOBP_Negative_Regulation_Of_Dephosphorylation	Human	Breast	rep_6	2.2e-04
TIPRL	GOBP_Negative_Regulation_Of_Protein_Dephosphorylation	Human	Breast	rep_6	9.9e-09
TIPRL	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_6	6.2e-08
TIPRL	GOBP_Protein_Dephosphorylation	Human	Breast	rep_6	6.7e-05
TIPRL	GOBP_Regulation_Of_Dephosphorylation	Human	Breast	rep_6	4.4e-05
TIPRL	GOBP_Regulation_Of_Phosphatase_Activity	Human	Breast	rep_6	7.7e-08
TIPRL	GOBP_Regulation_Of_Phosphoprotein_Phosphatase_Activity	Human	Breast	rep_6	5.8e-06
TIPRL	GOBP_Regulation_Of_Protein_Dephosphorylation	Human	Breast	rep_6	2.6e-04
TIPRL	GOBP_Tor_Signaling	Human	Breast	rep_6	2.9e-08
TIPRL	GOBP_Negative_Regulation_Of_Catalytic_Activity	Human	Lung	rep_1	1.4e-08
TIPRL	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	5.7e-10
TIPRL	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07

Top

TIPRL function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

TIPRL function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for TIPRL envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for TIPRL

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for TIPRL

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source