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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: PAN3 (spascer ID:255967)

Gene summary for PAN3

Gene summary

Gene information
	Species	Human
	Gene symbol	PAN3
	Gene ID	255967
	Gene name	poly(A) specific ribonuclease subunit PAN3
	Synonyms	-
	Cytomap	13q12.2
	Type of gene	protein-coding
	Description	PAN2-PAN3 deadenylation complex subunit PAN3PAB-dependent poly(A)-specific ribonuclease subunit 3PAB-dependent poly(A)-specific ribonuclease subunit PAN3PAB1P-dependent poly(A)-nucleasePAB1P-dependent poly(A)-specific ribonucleasePABP-dependent poly(
	Modification date	20220513
	UniProtAcc	Q58A45

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
PAN3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	21873635	Process
PAN3	GO:0000932	P-body	21873635	Component
PAN3	GO:0008143	poly(A) binding	21873635	Function
PAN3	GO:0031251	PAN complex	21873635	Component

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Spatial pattern events for PAN3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
PAN3	Human	Intestine	rep_colon1	34417225	2.53e-14
PAN3	Human	Intestine	rep_colon4	34417225	1.14e-15
PAN3	Human	Liver	rep_liver1	34417225	7.92e-09
PAN3	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has PAN3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
PAN3	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
PAN3	GOBP_Mrna_Metabolic_Process	Human	Intestine	A3	7.7e-20
PAN3	GOBP_Mrna_Processing	Human	Intestine	A3	4.9e-17
PAN3	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Intestine	A3	2.8e-18
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process	Human	Intestine	A3	2.8e-10
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process_Deadenylation_Dependent_Decay	Human	Intestine	A3	1.5e-09
PAN3	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Human	Intestine	A3	1.9e-08
PAN3	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Intestine	A3	5.9e-24
PAN3	GOBP_Rna_Catabolic_Process	Human	Intestine	A3	5.9e-24
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Intestine	A3	2.3e-07
PAN3	GOBP_Rna_Processing	Human	Intestine	A3	3.9e-09
PAN3	GOBP_Nuclear_Transcribed_Mrna_Poly_A_Tail_Shortening	Human	Intestine	A8	1.6e-28
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis_Exonucleolytic	Human	Intestine	A8	6.5e-10
PAN3	GOBP_Mrna_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process	Human	Pancreas	PDAC-B-st1	9.4e-06
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process_Deadenylation_Dependent_Decay	Human	Pancreas	PDAC-B-st1	5.2e-05
PAN3	GOBP_Rna_Catabolic_Process	Human	Pancreas	PDAC-B-st1	8.0e-05
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Pancreas	PDAC-B-st1	3.3e-05
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis_Exonucleolytic	Human	Pancreas	PDAC-A-st2	1.4e-05
PAN3	GOBP_Nuclear_Transcribed_Mrna_Poly_A_Tail_Shortening	Human	Uterus	rep_25	4.8e-07
PAN3	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process	Human	Uterus	rep_26	8.1e-10
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process_Deadenylation_Dependent_Decay	Human	Uterus	rep_26	2.2e-12
PAN3	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Uterus	rep_26	2.6e-06
PAN3	GOBP_Rna_Catabolic_Process	Human	Uterus	rep_26	2.7e-07
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis_Exonucleolytic	Human	Uterus	rep_26	9.7e-09
PAN3	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Breast	rep_5	5.3e-06
PAN3	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
PAN3	GOBP_Mrna_Metabolic_Process	Human	Breast	rep_6	3.0e-08
PAN3	GOBP_Mrna_Processing	Human	Breast	rep_6	1.5e-06
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process	Human	Breast	rep_6	8.1e-07
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process_Deadenylation_Dependent_Decay	Human	Breast	rep_6	1.7e-04
PAN3	GOBP_Nuclear_Transcribed_Mrna_Poly_A_Tail_Shortening	Human	Breast	rep_6	4.1e-04
PAN3	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Human	Breast	rep_6	2.6e-05
PAN3	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Breast	rep_6	7.7e-08
PAN3	GOBP_Rna_Catabolic_Process	Human	Breast	rep_6	3.9e-06
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Breast	rep_6	2.8e-06
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis_Exonucleolytic	Human	Breast	rep_6	3.0e-08
PAN3	GOBP_Rna_Processing	Human	Breast	rep_6	3.5e-06
PAN3	GOBP_Nuclear_Transcribed_Mrna_Catabolic_Process_Deadenylation_Dependent_Decay	Human	Skin	P5_rep1	4.0e-09
PAN3	GOBP_Mrna_Metabolic_Process	Human	Skin	P5_rep3	1.8e-08
PAN3	GOBP_Mrna_Processing	Human	Skin	P5_rep3	9.7e-09
PAN3	GOBP_Nuclear_Transcribed_Mrna_Poly_A_Tail_Shortening	Human	Skin	P10_rep1	7.2e-08
PAN3	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Lung	rep_1	8.8e-08

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PAN3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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PAN3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for PAN3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for PAN3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for PAN3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source