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Spatial pattern gene: KHDC4 (spascer ID:22889) |
Gene summary for KHDC4 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | KHDC4 | Gene ID | 22889 |
| Gene name | KH domain containing 4, pre-mRNA splicing factor |
| Synonyms | BLOM7|KIAA0907|SNORA80EHG |
| Cytomap | 1q22 |
| Type of gene | protein-coding |
| Description | KH homology domain-containing protein 4brings lots of money 7pre-mRNA splicing factor protein KHDC4protein BLOM7 |
| Modification date | 20220513 |
| UniProtAcc | Q7Z7F0 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| KHDC4 | GO:0003723 | RNA binding | 21873635 | Function |
| KHDC4 | GO:0005634 | nucleus | 21873635 | Component |
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Spatial pattern events for KHDC4 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| KHDC4 | Human | Intestine | rep_colon1 | 34417225 | 2.09e-08 |
| KHDC4 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| KHDC4 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| KHDC4 | Human | Breast | 1160920F | 34493872 | 1.43e-10 |
| KHDC4 | Human | Breast | CID4290 | 34493872 | 2.23e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver2_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4290_H&E  |  |
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Spatial pattern pathway has KHDC4 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| KHDC4 | GOBP_Mrna_Metabolic_Process | Human | Intestine | A3 | 7.7e-20 |
| KHDC4 | GOBP_Mrna_Processing | Human | Intestine | A3 | 4.9e-17 |
| KHDC4 | GOBP_Mrna_Splice_Site_Selection | Human | Intestine | A3 | 6.7e-13 |
| KHDC4 | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Intestine | A3 | 1.6e-07 |
| KHDC4 | GOBP_Rna_Processing | Human | Intestine | A3 | 3.9e-09 |
| KHDC4 | GOBP_Rna_Splicing | Human | Intestine | A3 | 3.3e-19 |
| KHDC4 | GOBP_Rna_Splicing_Via_Transesterification_Reactions | Human | Intestine | A3 | 2.2e-12 |
| KHDC4 | GOBP_Spliceosomal_Complex_Assembly | Human | Intestine | A3 | 8.7e-10 |
| KHDC4 | GOBP_Mrna_Metabolic_Process | Human | Pancreas | PDAC-B-st1 | 2.6e-05 |
| KHDC4 | GOBP_Rna_Splicing | Human | Pancreas | PDAC-B-st1 | 1.9e-05 |
| KHDC4 | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Uterus | rep_26 | 4.6e-06 |
| KHDC4 | GOBP_Rna_Splicing | Human | Uterus | rep_26 | 1.0e-05 |
| KHDC4 | GOBP_Spliceosomal_Complex_Assembly | Human | Uterus | rep_26 | 5.6e-09 |
| KHDC4 | GOBP_Mrna_Metabolic_Process | Human | Breast | rep_6 | 3.0e-08 |
| KHDC4 | GOBP_Mrna_Processing | Human | Breast | rep_6 | 1.5e-06 |
| KHDC4 | GOBP_Mrna_Splice_Site_Selection | Human | Breast | rep_6 | 7.1e-06 |
| KHDC4 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Human | Breast | rep_6 | 1.3e-07 |
| KHDC4 | GOBP_Ribonucleoprotein_Complex_Subunit_Organization | Human | Breast | rep_6 | 1.4e-08 |
| KHDC4 | GOBP_Rna_Processing | Human | Breast | rep_6 | 3.5e-06 |
| KHDC4 | GOBP_Rna_Splicing | Human | Breast | rep_6 | 1.1e-09 |
| KHDC4 | GOBP_Rna_Splicing_Via_Transesterification_Reactions | Human | Breast | rep_6 | 5.4e-08 |
| KHDC4 | GOBP_Spliceosomal_Complex_Assembly | Human | Breast | rep_6 | 2.2e-12 |
| KHDC4 | GOBP_Mrna_Metabolic_Process | Human | Skin | P5_rep3 | 1.8e-08 |
| KHDC4 | GOBP_Mrna_Processing | Human | Skin | P5_rep3 | 9.7e-09 |
| KHDC4 | GOBP_Mrna_Splice_Site_Selection | Human | Skin | P10_rep2 | 2.9e-12 |
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KHDC4 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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KHDC4 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for KHDC4 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for KHDC4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for KHDC4 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
