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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CLSTN1 (spascer ID:22883)

Gene summary for CLSTN1

Gene summary

Gene information
	Species	Human
	Gene symbol	CLSTN1
	Gene ID	22883
	Gene name	calsyntenin 1
	Synonyms	ALC-ALPHA\|CDHR12\|CST-1\|CSTN1\|PIK3CD\|XB31alpha\|alcalpha1\|alcalpha2
	Cytomap	1p36.22
	Type of gene	protein-coding
	Description	calsyntenin-1alcadein-alphaalzheimer-related cadherin-like proteincadherin-related family member 12non-classical cadherin XB31alpha
	Modification date	20220513
	UniProtAcc	O94985

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CLSTN1	GO:0009986	cell surface	21873635	Component
CLSTN1	GO:0045211	postsynaptic membrane	21873635	Component
CLSTN1	GO:0050806	positive regulation of synaptic transmission	21873635	Process
CLSTN1	GO:0051965	positive regulation of synapse assembly	21873635	Process

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Spatial pattern events for CLSTN1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CLSTN1	Human	Brain	rep_1	33558695	1.72e-14
CLSTN1	Human	Brain	rep_2	33558695	6.51e-10
CLSTN1	Human	Brain	rep_3	33558695	4.93e-15
CLSTN1	Human	Brain	rep_4	33558695	5.14e-08
CLSTN1	Human	Brain	rep_7	33558695	3.14e-07
CLSTN1	Human	Brain	rep_8	33558695	3.67e-10
CLSTN1	Human	Brain	rep_9	33558695	3.01e-15
CLSTN1	Human	Brain	rep_10	33558695	3.23e-15
CLSTN1	Human	Brain	rep_11	33558695	3.36e-15
CLSTN1	Human	Brain	rep_12	33558695	3.65e-15
CLSTN1	Human	Prostate	rep_9	29925878	2.50e-09
CLSTN1	Human	Bladder	rep_1	34385456	8.93e-15
CLSTN1	Human	Intestine	rep_colon1	34417225	1.95e-15
CLSTN1	Human	Intestine	rep_colon2	34417225	8.12e-16
CLSTN1	Human	Intestine	rep_colon4	34417225	1.14e-15
CLSTN1	Human	Liver	rep_liver1	34417225	1.08e-15
CLSTN1	Human	Liver	rep_liver2	34417225	6.98e-16
CLSTN1	Human	Liver	rep_liver3	34417225	1.56e-06
CLSTN1	Human	Intestine	A1	33406409	2.09e-15
CLSTN1	Human	Intestine	A2	33406409	2.47e-15
CLSTN1	Human	Uterus	rep_1	34857954	3.33e-08
CLSTN1	Human	Uterus	rep_2	34857954	1.93e-09
CLSTN1	Human	Uterus	rep_3	34857954	1.80e-09
CLSTN1	Human	Breast	A6	34650042	9.30e-08
CLSTN1	Human	Breast	E1	34650042	1.34e-06
CLSTN1	Human	Breast	E2	34650042	2.34e-06
CLSTN1	Human	Breast	E3	34650042	1.51e-07
CLSTN1	Human	Breast	G2	34650042	5.13e-07
CLSTN1	Human	Breast	1142243F	34493872	8.65e-06
CLSTN1	Human	Breast	1160920F	34493872	1.48e-15
CLSTN1	Human	Breast	CID4465	34493872	5.46e-09
CLSTN1	Human	Breast	CID44971	34493872	2.88e-09
CLSTN1	Human	Lung	rep_1	35355018	4.99e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_7_H&E
Brain_rep_8_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Bladder_rep_1_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_A6_H&E
Breast_E1_H&E
Breast_E2_H&E
Breast_E3_H&E
Breast_G2_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has CLSTN1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CLSTN1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
CLSTN1	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
CLSTN1	GOBP_Cell_Growth	Human	Brain	rep_4	1.0e-14
CLSTN1	GOBP_Growth	Human	Brain	rep_4	1.0e-14
CLSTN1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
CLSTN1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
CLSTN1	GOBP_Cell_Growth	Human	Liver	rep_1	2.1e-52
CLSTN1	GOBP_Growth	Human	Liver	rep_1	2.1e-52
CLSTN1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
CLSTN1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
CLSTN1	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
CLSTN1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
CLSTN1	GOBP_Cell_Growth	Human	Intestine	rep_colon2	1.5e-57
CLSTN1	GOBP_Growth	Human	Intestine	rep_colon2	1.5e-57
CLSTN1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
CLSTN1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
CLSTN1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
CLSTN1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
CLSTN1	GOBP_Biological_Adhesion	Human	Intestine	A3	6.7e-11
CLSTN1	GOBP_Cell_Cell_Adhesion	Human	Intestine	A3	2.5e-07
CLSTN1	GOBP_Cell_Cell_Signaling	Human	Intestine	A3	6.4e-08
CLSTN1	GOBP_Cell_Growth	Human	Intestine	A3	1.3e-16
CLSTN1	GOBP_Cell_Junction_Assembly	Human	Intestine	A3	6.2e-12
CLSTN1	GOBP_Cell_Junction_Organization	Human	Intestine	A3	1.1e-08
CLSTN1	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
CLSTN1	GOBP_Developmental_Maturation	Human	Intestine	A3	2.5e-14
CLSTN1	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
CLSTN1	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Intestine	A3	7.6e-11
CLSTN1	GOBP_Growth	Human	Intestine	A3	3.3e-16
CLSTN1	GOBP_Positive_Regulation_Of_Cell_Junction_Assembly	Human	Intestine	A3	2.9e-11
CLSTN1	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	1.9e-13
CLSTN1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
CLSTN1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
CLSTN1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
CLSTN1	GOBP_Positive_Regulation_Of_Nervous_System_Development	Human	Intestine	A3	1.1e-14
CLSTN1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
CLSTN1	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
CLSTN1	GOBP_Protein_Localization_To_Cell_Periphery	Human	Intestine	A3	4.6e-14
CLSTN1	GOBP_Regulation_Of_Cell_Junction_Assembly	Human	Intestine	A3	3.1e-14
CLSTN1	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
CLSTN1	GOBP_Regulation_Of_Growth	Human	Intestine	A3	3.6e-10
CLSTN1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
CLSTN1	GOBP_Regulation_Of_Nervous_System_Development	Human	Intestine	A3	2.8e-11
CLSTN1	GOBP_Regulation_Of_Synapse_Assembly	Human	Intestine	A3	2.4e-07
CLSTN1	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Intestine	A3	4.7e-08
CLSTN1	GOBP_Synapse_Assembly	Human	Intestine	A3	3.1e-18
CLSTN1	GOBP_Synaptic_Signaling	Human	Intestine	A3	5.0e-10
CLSTN1	GOBP_Vesicle_Mediated_Transport_To_The_Plasma_Membrane	Human	Intestine	A3	4.6e-07
CLSTN1	GOBP_Cell_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Intestine	A8	1.2e-11
CLSTN1	GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Intestine	A8	1.2e-14
CLSTN1	GOBP_Neurotransmitter_Receptor_Transport	Human	Intestine	A8	5.8e-13
CLSTN1	GOBP_Neurotransmitter_Receptor_Transport_To_Plasma_Membrane	Human	Intestine	A8	5.6e-14
CLSTN1	GOBP_Positive_Regulation_Of_Synapse_Assembly	Human	Intestine	A8	3.9e-07
CLSTN1	GOBP_Positive_Regulation_Of_Synaptic_Transmission	Human	Intestine	A8	1.7e-08
CLSTN1	GOBP_Protein_Localization_To_Postsynapse	Human	Intestine	A8	4.3e-10
CLSTN1	GOBP_Receptor_Localization_To_Synapse	Human	Intestine	A8	9.9e-09
CLSTN1	GOBP_Regulation_Of_Postsynaptic_Membrane_Neurotransmitter_Receptor_Levels	Human	Intestine	A8	5.2e-13
CLSTN1	GOBP_Regulation_Of_Synapse_Maturation	Human	Intestine	A8	1.0e-08
CLSTN1	GOBP_Synapse_Maturation	Human	Intestine	A8	8.3e-12
CLSTN1	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Pancreas	PDAC-B-st1	5.9e-05
CLSTN1	GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Uterus	rep_1	2.1e-06
CLSTN1	GOBP_Regulation_Of_Synapse_Assembly	Human	Uterus	rep_2	1.5e-06
CLSTN1	GOBP_Developmental_Maturation	Human	Uterus	rep_26	1.1e-06
CLSTN1	GOBP_Neurotransmitter_Receptor_Transport	Human	Uterus	rep_26	6.2e-18
CLSTN1	GOBP_Neurotransmitter_Receptor_Transport_To_Plasma_Membrane	Human	Uterus	rep_26	4.9e-14
CLSTN1	GOBP_Protein_Localization_To_Postsynapse	Human	Uterus	rep_26	8.3e-11
CLSTN1	GOBP_Receptor_Localization_To_Synapse	Human	Uterus	rep_26	4.1e-11
CLSTN1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
CLSTN1	GOBP_Regulation_Of_Synapse_Structure_Or_Activity	Human	Uterus	rep_26	2.3e-07
CLSTN1	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Uterus	rep_26	1.2e-08
CLSTN1	GOBP_Synaptic_Signaling	Human	Uterus	rep_26	3.3e-08
CLSTN1	GOBP_Biological_Adhesion	Human	Uterus	rep_29	3.3e-06
CLSTN1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
CLSTN1	GOBP_Biological_Adhesion	Human	Breast	rep_1	4.0e-110
CLSTN1	GOBP_Cell_Cell_Adhesion	Human	Breast	rep_1	3.6e-45
CLSTN1	GOBP_Cell_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Breast	rep_1	3.2e-141
CLSTN1	GOBP_Cell_Growth	Human	Breast	rep_1	6.0e-15
CLSTN1	GOBP_Cell_Junction_Assembly	Human	Breast	rep_1	4.4e-63
CLSTN1	GOBP_Cell_Junction_Organization	Human	Breast	rep_1	3.0e-10
CLSTN1	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
CLSTN1	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
CLSTN1	GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Breast	rep_1	1.2e-106
CLSTN1	GOBP_Neurotransmitter_Receptor_Transport	Human	Breast	rep_1	4.6e-23
CLSTN1	GOBP_Neurotransmitter_Receptor_Transport_To_Plasma_Membrane	Human	Breast	rep_1	2.4e-21
CLSTN1	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	3.5e-04
CLSTN1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
CLSTN1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
CLSTN1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
CLSTN1	GOBP_Positive_Regulation_Of_Nervous_System_Development	Human	Breast	rep_1	5.9e-13
CLSTN1	GOBP_Positive_Regulation_Of_Synapse_Assembly	Human	Breast	rep_1	4.5e-20
CLSTN1	GOBP_Protein_Localization_To_Cell_Junction	Human	Breast	rep_1	3.7e-207
CLSTN1	GOBP_Protein_Localization_To_Cell_Periphery	Human	Breast	rep_1	7.2e-19
CLSTN1	GOBP_Protein_Localization_To_Synapse	Human	Breast	rep_1	4.8e-58
CLSTN1	GOBP_Receptor_Localization_To_Synapse	Human	Breast	rep_1	1.4e-27
CLSTN1	GOBP_Regulation_Of_Cell_Junction_Assembly	Human	Breast	rep_1	8.1e-17
CLSTN1	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
CLSTN1	GOBP_Regulation_Of_Growth	Human	Breast	rep_1	2.3e-04
CLSTN1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
CLSTN1	GOBP_Regulation_Of_Nervous_System_Development	Human	Breast	rep_1	2.9e-16
CLSTN1	GOBP_Regulation_Of_Postsynaptic_Membrane_Neurotransmitter_Receptor_Levels	Human	Breast	rep_1	3.7e-40
CLSTN1	GOBP_Regulation_Of_Synapse_Maturation	Human	Breast	rep_1	1.2e-151
CLSTN1	GOBP_Synapse_Maturation	Human	Breast	rep_1	1.3e-156
CLSTN1	GOBP_Synapse_Organization	Human	Breast	rep_1	3.0e-09
CLSTN1	GOBP_Synaptic_Signaling	Human	Breast	rep_1	3.5e-04
CLSTN1	GOBP_Vesicle_Mediated_Transport_In_Synapse	Human	Breast	rep_1	6.1e-127
CLSTN1	GOBP_Developmental_Maturation	Human	Breast	rep_5	2.3e-12
CLSTN1	GOBP_Growth	Human	Breast	rep_5	5.4e-12
CLSTN1	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
CLSTN1	GOBP_Positive_Regulation_Of_Synaptic_Transmission	Human	Breast	rep_5	2.7e-12
CLSTN1	GOBP_Protein_Localization_To_Postsynapse	Human	Breast	rep_5	1.9e-05
CLSTN1	GOBP_Regulation_Of_Synapse_Assembly	Human	Breast	rep_5	2.1e-05
CLSTN1	GOBP_Synapse_Assembly	Human	Breast	rep_5	3.2e-05
CLSTN1	GOBP_Cell_Cell_Signaling	Human	Breast	rep_6	5.0e-05
CLSTN1	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Breast	rep_6	3.8e-07
CLSTN1	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
CLSTN1	GOBP_Regulation_Of_Synapse_Structure_Or_Activity	Human	Breast	rep_6	1.2e-04
CLSTN1	GOBP_Regulation_Of_Trans_Synaptic_Signaling	Human	Breast	rep_6	1.3e-06
CLSTN1	GOBP_Vesicle_Mediated_Transport_To_The_Plasma_Membrane	Human	Breast	rep_6	2.0e-08
CLSTN1	GOBP_Neurotransmitter_Receptor_Transport	Human	Skin	P2_rep2	5.1e-08
CLSTN1	GOBP_Protein_Localization_To_Cell_Periphery	Human	Skin	P5_rep1	2.4e-09
CLSTN1	GOBP_Positive_Regulation_Of_Synapse_Assembly	Human	Skin	P5_rep3	1.2e-14
CLSTN1	GOBP_Cell_Growth	Human	Skin	P9_rep3	4.1e-08
CLSTN1	GOBP_Biological_Adhesion	Human	Lung	rep_2	6.6e-07
CLSTN1	GOBP_Cell_Cell_Adhesion	Human	Lung	rep_2	5.3e-07
CLSTN1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07

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CLSTN1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CLSTN1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CLSTN1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CLSTN1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CLSTN1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source