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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SEC31A (spascer ID:22872)

Gene summary for SEC31A

Gene summary

Gene information
	Species	Human
	Gene symbol	SEC31A
	Gene ID	22872
	Gene name	SEC31 homolog A, COPII coat complex component
	Synonyms	ABP125\|ABP130\|HPBKS\|HSPC275\|HSPC334\|NEDSOSB\|SEC31L1
	Cytomap	4q21.22
	Type of gene	protein-coding
	Description	protein transport protein Sec31ASEC31 homolog A, COPII coating complex componentSEC31-like protein 1SEC31-related protein Aweb1-like proteinyeast Sec31p homolog
	Modification date	20220513
	UniProtAcc	O94979

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SEC31A	GO:0005198	structural molecule activity	21873635	Function
SEC31A	GO:0006886	intracellular protein transport	21873635	Process
SEC31A	GO:0007029	endoplasmic reticulum organization	21873635	Process
SEC31A	GO:0030127	COPII vesicle coat	21873635	Component
SEC31A	GO:0070971	endoplasmic reticulum exit site	21873635	Component
SEC31A	GO:0090110	COPII-coated vesicle cargo loading	21873635	Process

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Spatial pattern events for SEC31A

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SEC31A	Human	Intestine	rep_colon1	34417225	6.88e-12
SEC31A	Human	Intestine	rep_colon3	34417225	3.85e-06
SEC31A	Human	Intestine	rep_colon4	34417225	1.65e-06
SEC31A	Human	Liver	rep_liver1	34417225	1.06e-14
SEC31A	Human	Liver	rep_liver2	34417225	1.72e-07
SEC31A	Human	Liver	rep_liver4	34417225	1.48e-06
SEC31A	Human	Uterus	rep_1	34857954	9.06e-09
SEC31A	Human	Uterus	rep_2	34857954	4.63e-15
SEC31A	Human	Uterus	rep_3	34857954	1.66e-15
SEC31A	Human	Uterus	rep_4	34857954	1.82e-15
SEC31A	Human	Breast	CID44971	34493872	8.50e-10
SEC31A	Human	Heart	w9_s3	31835037	5.46e-03

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has SEC31A envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SEC31A	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
SEC31A	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Human	Intestine	A3	3.0e-16
SEC31A	GOBP_Copii_Coated_Vesicle_Budding	Human	Intestine	A3	3.5e-11
SEC31A	GOBP_Endomembrane_System_Organization	Human	Intestine	A3	1.6e-16
SEC31A	GOBP_Establishment_Of_Organelle_Localization	Human	Intestine	A3	9.7e-13
SEC31A	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
SEC31A	GOBP_Golgi_Vesicle_Transport	Human	Intestine	A3	9.2e-10
SEC31A	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
SEC31A	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
SEC31A	GOBP_Membrane_Organization	Human	Intestine	A3	2.7e-18
SEC31A	GOBP_Organelle_Localization	Human	Intestine	A3	5.1e-12
SEC31A	GOBP_Response_To_Calcium_Ion	Human	Intestine	A3	1.7e-07
SEC31A	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Human	Intestine	A3	2.1e-18
SEC31A	GOBP_Response_To_Inorganic_Substance	Human	Intestine	A3	6.8e-07
SEC31A	GOBP_Response_To_Topologically_Incorrect_Protein	Human	Intestine	A3	1.7e-15
SEC31A	GOBP_Vesicle_Localization	Human	Intestine	A3	1.3e-07
SEC31A	GOBP_Vesicle_Organization	Human	Intestine	A3	3.0e-15
SEC31A	GOBP_Vesicle_Targeting	Human	Intestine	A3	4.2e-07
SEC31A	GOBP_Antigen_Processing_And_Presentation	Human	Intestine	A8	1.7e-13
SEC31A	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen	Human	Intestine	A8	8.9e-10
SEC31A	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen_Via_Mhc_Class_I	Human	Intestine	A8	6.4e-13
SEC31A	GOBP_Copii_Coated_Vesicle_Cargo_Loading	Human	Intestine	A8	1.9e-07
SEC31A	GOBP_Endoplasmic_Reticulum_Organization	Human	Intestine	A8	3.1e-12
SEC31A	GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport	Human	Intestine	A8	2.4e-10
SEC31A	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Human	Intestine	A8	6.5e-14
SEC31A	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Human	Intestine	A8	2.7e-25
SEC31A	GOBP_Response_To_Metal_Ion	Human	Intestine	A8	2.1e-21
SEC31A	GOBP_Vesicle_Budding_From_Membrane	Human	Intestine	A8	4.3e-15
SEC31A	GOBP_Vesicle_Targeting_To_From_Or_Within_Golgi	Human	Intestine	A8	2.6e-12
SEC31A	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Pancreas	PDAC-B-st1	7.1e-05
SEC31A	GOBP_Endoplasmic_Reticulum_Organization	Human	Pancreas	PDAC-B-st1	4.9e-05
SEC31A	GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport	Human	Pancreas	PDAC-B-st1	9.2e-05
SEC31A	GOBP_Copii_Coated_Vesicle_Cargo_Loading	Human	Pancreas	PDAC-A-st2	1.6e-05
SEC31A	GOBP_Copii_Coated_Vesicle_Cargo_Loading	Human	Uterus	rep_1	5.5e-06
SEC31A	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen_Via_Mhc_Class_I	Human	Uterus	rep_26	2.2e-06
SEC31A	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Uterus	rep_26	7.6e-06
SEC31A	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Human	Uterus	rep_26	4.9e-11
SEC31A	GOBP_Copii_Coated_Vesicle_Budding	Human	Uterus	rep_26	2.0e-14
SEC31A	GOBP_Endoplasmic_Reticulum_Organization	Human	Uterus	rep_26	2.8e-06
SEC31A	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Human	Uterus	rep_26	5.9e-07
SEC31A	GOBP_Golgi_Vesicle_Transport	Human	Uterus	rep_26	3.4e-14
SEC31A	GOBP_Response_To_Topologically_Incorrect_Protein	Human	Uterus	rep_26	1.0e-06
SEC31A	GOBP_Vesicle_Cargo_Loading	Human	Uterus	rep_26	7.5e-06
SEC31A	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen	Human	Uterus	rep_28	2.7e-08
SEC31A	GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport	Human	Uterus	rep_29	6.3e-06
SEC31A	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
SEC31A	GOBP_Endomembrane_System_Organization	Human	Breast	rep_1	2.2e-04
SEC31A	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Human	Breast	rep_1	9.4e-14
SEC31A	GOBP_Establishment_Of_Organelle_Localization	Human	Breast	rep_1	6.5e-08
SEC31A	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
SEC31A	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Human	Breast	rep_1	1.9e-10
SEC31A	GOBP_Organelle_Localization	Human	Breast	rep_1	1.8e-08
SEC31A	GOBP_Response_To_Calcium_Ion	Human	Breast	rep_1	8.9e-75
SEC31A	GOBP_Response_To_Metal_Ion	Human	Breast	rep_1	3.0e-20
SEC31A	GOBP_Vesicle_Budding_From_Membrane	Human	Breast	rep_1	1.7e-07
SEC31A	GOBP_Vesicle_Localization	Human	Breast	rep_1	7.0e-11
SEC31A	GOBP_Vesicle_Organization	Human	Breast	rep_1	8.3e-15
SEC31A	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Human	Breast	rep_5	3.5e-04
SEC31A	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Human	Breast	rep_5	4.4e-06
SEC31A	GOBP_Response_To_Inorganic_Substance	Human	Breast	rep_5	1.8e-10
SEC31A	GOBP_Response_To_Topologically_Incorrect_Protein	Human	Breast	rep_5	3.6e-05
SEC31A	GOBP_Copii_Coated_Vesicle_Budding	Human	Breast	rep_6	2.0e-11
SEC31A	GOBP_Endoplasmic_Reticulum_Organization	Human	Breast	rep_6	5.1e-06
SEC31A	GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport	Human	Breast	rep_6	4.9e-08
SEC31A	GOBP_Golgi_Vesicle_Transport	Human	Breast	rep_6	2.0e-08
SEC31A	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
SEC31A	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
SEC31A	GOBP_Vesicle_Cargo_Loading	Human	Breast	rep_6	7.9e-04
SEC31A	GOBP_Vesicle_Targeting	Human	Breast	rep_6	3.4e-09
SEC31A	GOBP_Vesicle_Targeting_To_From_Or_Within_Golgi	Human	Breast	rep_6	6.9e-08
SEC31A	GOBP_Organelle_Localization	Human	Skin	P5_rep1	2.1e-13
SEC31A	GOBP_Vesicle_Localization	Human	Skin	P5_rep1	2.7e-08
SEC31A	GOBP_Vesicle_Organization	Human	Skin	P5_rep1	2.3e-09
SEC31A	GOBP_Copii_Coated_Vesicle_Cargo_Loading	Human	Skin	P10_rep3	2.8e-16
SEC31A	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Lung	rep_2	1.2e-07

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SEC31A function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SEC31A function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SEC31A envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SEC31A

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SEC31A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SEC31A	C0079744	Diffuse Large B-Cell Lymphoma	1	CTD_human