|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: DLGAP4 (spascer ID:22839) |
Gene summary for DLGAP4 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | DLGAP4 | Gene ID | 22839 |
| Gene name | DLG associated protein 4 |
| Synonyms | DAP-4|DAP4|DLP4|SAPAP-4|SAPAP4 |
| Cytomap | 20q11.23 |
| Type of gene | protein-coding |
| Description | disks large-associated protein 4PSD-95/SAP90-binding protein 4SAP90/PSD-95-associated protein 4discs large homolog associated protein 4 |
| Modification date | 20220513 |
| UniProtAcc | Q9Y2H0 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| DLGAP4 | GO:0060090 | molecular adaptor activity | 21873635 | Function |
| DLGAP4 | GO:0098962 | regulation of postsynaptic neurotransmitter receptor activity | 21873635 | Process |
| DLGAP4 | GO:0098978 | glutamatergic synapse | 21873635 | Component |
| DLGAP4 | GO:0099572 | postsynaptic specialization | 21873635 | Component |
Top |
Spatial pattern events for DLGAP4 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| DLGAP4 | Human | Brain | rep_10 | 33558695 | 6.91e-06 |
| DLGAP4 | Human | Intestine | rep_colon1 | 34417225 | 3.42e-15 |
| DLGAP4 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| DLGAP4 | Human | Intestine | rep_colon4 | 34417225 | 1.17e-11 |
| DLGAP4 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| DLGAP4 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| DLGAP4 | Human | Liver | rep_liver4 | 34417225 | 7.71e-16 |
| DLGAP4 | Human | Intestine | A2 | 33406409 | 4.41e-07 |
| DLGAP4 | Human | Uterus | rep_3 | 34857954 | 1.83e-12 |
| DLGAP4 | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_10_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Intestine_A2_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_CID44971_H&E  |  |
Top |
Spatial pattern pathway has DLGAP4 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| DLGAP4 | GOBP_Cell_Cell_Signaling | Human | Intestine | A3 | 6.4e-08 |
| DLGAP4 | GOBP_Nervous_System_Process | Human | Intestine | A3 | 9.7e-07 |
| DLGAP4 | GOBP_Regulation_Of_Trans_Synaptic_Signaling | Human | Intestine | A3 | 4.7e-08 |
| DLGAP4 | GOBP_Synaptic_Signaling | Human | Intestine | A3 | 5.0e-10 |
| DLGAP4 | GOBP_Regulation_Of_Nervous_System_Process | Human | Intestine | A8 | 3.7e-15 |
| DLGAP4 | GOBP_Regulation_Of_Neurotransmitter_Receptor_Activity | Human | Intestine | A8 | 1.5e-07 |
| DLGAP4 | GOBP_Regulation_Of_Postsynaptic_Neurotransmitter_Receptor_Activity | Human | Intestine | A8 | 3.7e-09 |
| DLGAP4 | GOBP_Regulation_Of_Nervous_System_Process | Human | Pancreas | PDAC-B-st1 | 1.5e-05 |
| DLGAP4 | GOBP_Regulation_Of_Trans_Synaptic_Signaling | Human | Pancreas | PDAC-B-st1 | 5.9e-05 |
| DLGAP4 | GOBP_Regulation_Of_Postsynaptic_Neurotransmitter_Receptor_Activity | Human | Pancreas | PDAC-G-st1 | 9.2e-05 |
| DLGAP4 | GOBP_Nervous_System_Process | Human | Uterus | rep_26 | 2.3e-07 |
| DLGAP4 | GOBP_Regulation_Of_Postsynaptic_Neurotransmitter_Receptor_Activity | Human | Uterus | rep_26 | 2.9e-08 |
| DLGAP4 | GOBP_Regulation_Of_Signaling_Receptor_Activity | Human | Uterus | rep_26 | 2.3e-07 |
| DLGAP4 | GOBP_Regulation_Of_System_Process | Human | Uterus | rep_26 | 6.6e-10 |
| DLGAP4 | GOBP_Regulation_Of_Trans_Synaptic_Signaling | Human | Uterus | rep_26 | 1.2e-08 |
| DLGAP4 | GOBP_Synaptic_Signaling | Human | Uterus | rep_26 | 3.3e-08 |
| DLGAP4 | GOBP_Nervous_System_Process | Human | Breast | rep_1 | 1.2e-04 |
| DLGAP4 | GOBP_Regulation_Of_Postsynaptic_Neurotransmitter_Receptor_Activity | Human | Breast | rep_1 | 4.7e-07 |
| DLGAP4 | GOBP_Regulation_Of_Signaling_Receptor_Activity | Human | Breast | rep_1 | 2.4e-84 |
| DLGAP4 | GOBP_Regulation_Of_System_Process | Human | Breast | rep_1 | 1.0e-09 |
| DLGAP4 | GOBP_Synaptic_Signaling | Human | Breast | rep_1 | 3.5e-04 |
| DLGAP4 | GOBP_Regulation_Of_Nervous_System_Process | Human | Breast | rep_5 | 1.3e-07 |
| DLGAP4 | GOBP_Regulation_Of_Neurotransmitter_Receptor_Activity | Human | Breast | rep_5 | 1.2e-12 |
| DLGAP4 | GOBP_Cell_Cell_Signaling | Human | Breast | rep_6 | 5.0e-05 |
| DLGAP4 | GOBP_Regulation_Of_Trans_Synaptic_Signaling | Human | Breast | rep_6 | 1.3e-06 |
| DLGAP4 | GOBP_Regulation_Of_Nervous_System_Process | Human | Skin | P2_rep2 | 3.2e-14 |
| DLGAP4 | GOBP_Regulation_Of_Neurotransmitter_Receptor_Activity | Human | Skin | P10_rep2 | 8.6e-11 |
| DLGAP4 | GOBP_Regulation_Of_Postsynaptic_Neurotransmitter_Receptor_Activity | Human | Skin | P10_rep2 | 1.1e-15 |
Top |
DLGAP4 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
DLGAP4 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for DLGAP4 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for DLGAP4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for DLGAP4 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
