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Spatial pattern gene: RHOBTB3 (spascer ID:22836) |
Gene summary for RHOBTB3 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | RHOBTB3 | Gene ID | 22836 |
| Gene name | Rho related BTB domain containing 3 |
| Synonyms | - |
| Cytomap | 5q15 |
| Type of gene | protein-coding |
| Description | rho-related BTB domain-containing protein 3 |
| Modification date | 20220513 |
| UniProtAcc | O94955 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| RHOBTB3 | GO:0003924 | GTPase activity | 21873635 | Function |
| RHOBTB3 | GO:0005525 | GTP binding | 21873635 | Function |
| RHOBTB3 | GO:0005856 | cytoskeleton | 21873635 | Component |
| RHOBTB3 | GO:0005886 | plasma membrane | 21873635 | Component |
| RHOBTB3 | GO:0005938 | cell cortex | 21873635 | Component |
| RHOBTB3 | GO:0007015 | actin filament organization | 21873635 | Process |
| RHOBTB3 | GO:0007163 | establishment or maintenance of cell polarity | 21873635 | Process |
| RHOBTB3 | GO:0008360 | regulation of cell shape | 21873635 | Process |
| RHOBTB3 | GO:0016477 | cell migration | 21873635 | Process |
| RHOBTB3 | GO:0019901 | protein kinase binding | 21873635 | Function |
| RHOBTB3 | GO:0030865 | cortical cytoskeleton organization | 21873635 | Process |
| RHOBTB3 | GO:0031410 | cytoplasmic vesicle | 21873635 | Component |
| RHOBTB3 | GO:0032956 | regulation of actin cytoskeleton organization | 21873635 | Process |
| RHOBTB3 | GO:0042995 | cell projection | 21873635 | Component |
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Spatial pattern events for RHOBTB3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| RHOBTB3 | Human | Brain | rep_9 | 33558695 | 3.01e-15 |
| RHOBTB3 | Human | Brain | rep_10 | 33558695 | 3.23e-15 |
| RHOBTB3 | Human | Brain | rep_11 | 33558695 | 3.36e-15 |
| RHOBTB3 | Human | Brain | rep_12 | 33558695 | 3.65e-15 |
| RHOBTB3 | Human | Intestine | rep_colon1 | 34417225 | 6.48e-15 |
| RHOBTB3 | Human | Intestine | rep_colon2 | 34417225 | 1.87e-09 |
| RHOBTB3 | Human | Liver | rep_liver1 | 34417225 | 3.57e-15 |
| RHOBTB3 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| RHOBTB3 | Human | Uterus | rep_2 | 34857954 | 1.77e-13 |
| RHOBTB3 | Human | Breast | 1142243F | 34493872 | 3.20e-07 |
| RHOBTB3 | Human | Breast | CID4465 | 34493872 | 2.25e-06 |
| RHOBTB3 | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| RHOBTB3 | Human | Skin | mel2_rep1 | 30154148 | 1.23e-09 |
| RHOBTB3 | Human | Lung | rep_1 | 35355018 | 5.56e-10 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_9_H&E  |  |
Brain_rep_10_H&E  |  |
Brain_rep_11_H&E  |  |
Brain_rep_12_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_2_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_CID4465_H&E  |  |
Breast_CID44971_H&E  |  |
Lung_rep_1_H&E  |  |
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Spatial pattern pathway has RHOBTB3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| RHOBTB3 | GOBP_Cell_Migration | Human | Brain | rep_1 | 3.1e-68 |
| RHOBTB3 | GOBP_Locomotion | Human | Brain | rep_1 | 3.1e-68 |
| RHOBTB3 | GOBP_Cell_Morphogenesis | Human | Brain | rep_4 | 1.0e-14 |
| RHOBTB3 | GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis | Human | Brain | rep_4 | 4.1e-17 |
| RHOBTB3 | GOBP_Cell_Migration | Human | Liver | rep_1 | 1.9e-71 |
| RHOBTB3 | GOBP_Cell_Morphogenesis | Human | Liver | rep_1 | 2.1e-52 |
| RHOBTB3 | GOBP_Locomotion | Human | Liver | rep_1 | 1.9e-71 |
| RHOBTB3 | GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis | Human | Liver | rep_1 | 1.0e-70 |
| RHOBTB3 | GOBP_Cell_Morphogenesis | Human | Intestine | rep_colon2 | 1.5e-57 |
| RHOBTB3 | GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis | Human | Intestine | rep_colon4 | 9.0e-12 |
| RHOBTB3 | GOBP_Cell_Migration | Human | Intestine | rep_liver2 | 1.0e-64 |
| RHOBTB3 | GOBP_Locomotion | Human | Intestine | rep_liver2 | 1.0e-64 |
| RHOBTB3 | GOBP_Cell_Migration | Human | Intestine | A3 | 1.6e-10 |
| RHOBTB3 | GOBP_Cell_Morphogenesis | Human | Intestine | A3 | 9.7e-08 |
| RHOBTB3 | GOBP_Cortical_Cytoskeleton_Organization | Human | Intestine | A3 | 6.9e-09 |
| RHOBTB3 | GOBP_Cytosolic_Transport | Human | Intestine | A3 | 5.9e-09 |
| RHOBTB3 | GOBP_Development_Of_Primary_Sexual_Characteristics | Human | Intestine | A3 | 5.0e-13 |
| RHOBTB3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Intestine | A3 | 2.7e-15 |
| RHOBTB3 | GOBP_Endosomal_Transport | Human | Intestine | A3 | 1.9e-09 |
| RHOBTB3 | GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity | Human | Intestine | A3 | 8.2e-09 |
| RHOBTB3 | GOBP_Intracellular_Transport | Human | Intestine | A3 | 7.6e-15 |
| RHOBTB3 | GOBP_Locomotion | Human | Intestine | A3 | 1.9e-08 |
| RHOBTB3 | GOBP_Male_Sex_Differentiation | Human | Intestine | A3 | 2.6e-16 |
| RHOBTB3 | GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis | Human | Intestine | A3 | 4.8e-12 |
| RHOBTB3 | GOBP_Regulation_Of_Cell_Morphogenesis | Human | Intestine | A3 | 5.8e-11 |
| RHOBTB3 | GOBP_Regulation_Of_Cell_Shape | Human | Intestine | A3 | 3.3e-10 |
| RHOBTB3 | GOBP_Regulation_Of_Cytoskeleton_Organization | Human | Intestine | A3 | 6.4e-13 |
| RHOBTB3 | GOBP_Regulation_Of_Organelle_Organization | Human | Intestine | A3 | 1.1e-11 |
| RHOBTB3 | GOBP_Reproduction | Human | Intestine | A3 | 4.6e-19 |
| RHOBTB3 | GOBP_Reproductive_System_Development | Human | Intestine | A3 | 2.9e-14 |
| RHOBTB3 | GOBP_Retrograde_Transport_Endosome_To_Golgi | Human | Intestine | A3 | 1.1e-08 |
| RHOBTB3 | GOBP_Sex_Differentiation | Human | Intestine | A3 | 6.1e-18 |
| RHOBTB3 | GOBP_Retrograde_Transport_Endosome_To_Golgi | Human | Pancreas | PDAC-B-st1 | 1.7e-06 |
| RHOBTB3 | GOBP_Endosomal_Transport | Human | Pancreas | PDAC-A-st2 | 9.1e-05 |
| RHOBTB3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Uterus | rep_1 | 1.6e-06 |
| RHOBTB3 | GOBP_Endosomal_Transport | Human | Uterus | rep_26 | 1.1e-06 |
| RHOBTB3 | GOBP_Actin_Filament_Based_Process | Human | Breast | rep_1 | 1.8e-86 |
| RHOBTB3 | GOBP_Actin_Filament_Organization | Human | Breast | rep_1 | 4.0e-75 |
| RHOBTB3 | GOBP_Cell_Migration | Human | Breast | rep_1 | 1.5e-45 |
| RHOBTB3 | GOBP_Cell_Morphogenesis | Human | Breast | rep_1 | 5.7e-26 |
| RHOBTB3 | GOBP_Cortical_Cytoskeleton_Organization | Human | Breast | rep_1 | 8.6e-18 |
| RHOBTB3 | GOBP_Cytoskeleton_Organization | Human | Breast | rep_1 | 1.3e-22 |
| RHOBTB3 | GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity | Human | Breast | rep_1 | 1.1e-43 |
| RHOBTB3 | GOBP_Locomotion | Human | Breast | rep_1 | 4.5e-54 |
| RHOBTB3 | GOBP_Regulation_Of_Actin_Filament_Based_Process | Human | Breast | rep_1 | 8.5e-105 |
| RHOBTB3 | GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis | Human | Breast | rep_1 | 4.6e-22 |
| RHOBTB3 | GOBP_Regulation_Of_Cell_Morphogenesis | Human | Breast | rep_1 | 5.0e-35 |
| RHOBTB3 | GOBP_Regulation_Of_Cell_Shape | Human | Breast | rep_1 | 3.2e-94 |
| RHOBTB3 | GOBP_Regulation_Of_Cytoskeleton_Organization | Human | Breast | rep_1 | 7.8e-76 |
| RHOBTB3 | GOBP_Regulation_Of_Organelle_Organization | Human | Breast | rep_1 | 8.7e-11 |
| RHOBTB3 | GOBP_Supramolecular_Fiber_Organization | Human | Breast | rep_1 | 2.8e-72 |
| RHOBTB3 | GOBP_Development_Of_Primary_Sexual_Characteristics | Human | Breast | rep_5 | 3.0e-05 |
| RHOBTB3 | GOBP_Developmental_Process_Involved_In_Reproduction | Human | Breast | rep_5 | 1.5e-12 |
| RHOBTB3 | GOBP_Reproduction | Human | Breast | rep_5 | 8.1e-06 |
| RHOBTB3 | GOBP_Reproductive_System_Development | Human | Breast | rep_5 | 3.6e-15 |
| RHOBTB3 | GOBP_Cytosolic_Transport | Human | Breast | rep_6 | 2.6e-05 |
| RHOBTB3 | GOBP_Endosomal_Transport | Human | Breast | rep_6 | 1.7e-13 |
| RHOBTB3 | GOBP_Intracellular_Transport | Human | Breast | rep_6 | 1.3e-08 |
| RHOBTB3 | GOBP_Male_Sex_Differentiation | Human | Breast | rep_6 | 2.0e-08 |
| RHOBTB3 | GOBP_Retrograde_Transport_Endosome_To_Golgi | Human | Breast | rep_6 | 7.5e-05 |
| RHOBTB3 | GOBP_Sex_Differentiation | Human | Breast | rep_6 | 4.2e-05 |
| RHOBTB3 | GOBP_Cytoskeleton_Organization | Human | Skin | P9_rep3 | 3.1e-12 |
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RHOBTB3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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RHOBTB3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for RHOBTB3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for RHOBTB3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for RHOBTB3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
