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Spatial pattern gene: COG2 (spascer ID:22796) |
Gene summary for COG2 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | COG2 | Gene ID | 22796 |
| Gene name | component of oligomeric golgi complex 2 |
| Synonyms | CDG2Q|LDLC |
| Cytomap | 1q42.2 |
| Type of gene | protein-coding |
| Description | conserved oligomeric Golgi complex subunit 2COG complex subunit 2brefeldin A-sensitive, peripheral Golgi proteinconserved oligomeric Golgi complex protein 2low density lipoprotein receptor defect C complementinglow density lipoprotein receptor defect |
| Modification date | 20220513 |
| UniProtAcc | Q14746 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| COG2 | GO:0006891 | intra-Golgi vesicle-mediated transport | 21873635 | Process |
| COG2 | GO:0007030 | Golgi organization | 21873635 | Process |
| COG2 | GO:0017119 | Golgi transport complex | 21873635 | Component |
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Spatial pattern events for COG2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| COG2 | Human | Intestine | rep_colon1 | 34417225 | 5.05e-11 |
| COG2 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| COG2 | Human | Liver | rep_liver1 | 34417225 | 1.00e-06 |
| COG2 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
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Spatial pattern pathway has COG2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| COG2 | GOBP_Endomembrane_System_Organization | Human | Intestine | A3 | 1.6e-16 |
| COG2 | GOBP_Establishment_Of_Protein_Localization | Human | Intestine | A3 | 5.0e-10 |
| COG2 | GOBP_Golgi_Organization | Human | Intestine | A3 | 2.9e-07 |
| COG2 | GOBP_Golgi_Vesicle_Transport | Human | Intestine | A3 | 9.2e-10 |
| COG2 | GOBP_Intracellular_Transport | Human | Intestine | A3 | 7.6e-15 |
| COG2 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Human | Intestine | A8 | 2.4e-10 |
| COG2 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Human | Pancreas | PDAC-B-st1 | 9.2e-05 |
| COG2 | GOBP_Golgi_Organization | Human | Pancreas | PDAC-B-st1 | 7.2e-05 |
| COG2 | GOBP_Golgi_Vesicle_Transport | Human | Uterus | rep_26 | 3.4e-14 |
| COG2 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Human | Uterus | rep_29 | 6.3e-06 |
| COG2 | GOBP_Intra_Golgi_Vesicle_Mediated_Transport | Human | Uterus | rep_29 | 3.3e-07 |
| COG2 | GOBP_Endomembrane_System_Organization | Human | Breast | rep_1 | 2.2e-04 |
| COG2 | GOBP_Establishment_Of_Protein_Localization | Human | Breast | rep_1 | 7.2e-05 |
| COG2 | GOBP_Golgi_Organization | Human | Breast | rep_1 | 6.6e-40 |
| COG2 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Human | Breast | rep_6 | 4.9e-08 |
| COG2 | GOBP_Golgi_Vesicle_Transport | Human | Breast | rep_6 | 2.0e-08 |
| COG2 | GOBP_Intra_Golgi_Vesicle_Mediated_Transport | Human | Breast | rep_6 | 1.3e-05 |
| COG2 | GOBP_Intracellular_Transport | Human | Breast | rep_6 | 1.3e-08 |
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COG2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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COG2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for COG2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for COG2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for COG2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
