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Spatial pattern gene: SLC51A (spascer ID:200931) |
Gene summary for SLC51A |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | SLC51A | Gene ID | 200931 |
| Gene name | solute carrier family 51 subunit alpha |
| Synonyms | OSTA|OSTalpha|PFIC6 |
| Cytomap | 3q29 |
| Type of gene | protein-coding |
| Description | organic solute transporter subunit alphaOST-alphaorganic solute transporter alphaorganic solute transporter, alpha subunitsolute carrier family 51 alpha subunit |
| Modification date | 20220513 |
| UniProtAcc | Q86UW1 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| SLC51A | GO:0005215 | transporter activity | 21873635 | Function |
| SLC51A | GO:0005789 | endoplasmic reticulum membrane | 21873635 | Component |
| SLC51A | GO:0005886 | plasma membrane | 21873635 | Component |
| SLC51A | GO:0006810 | transport | 21873635 | Process |
| SLC51A | GO:0015721 | bile acid and bile salt transport | 21873635 | Process |
| SLC51A | GO:0016021 | integral component of membrane | 21873635 | Component |
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Spatial pattern events for SLC51A |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| SLC51A | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver1_H&E  |  |
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Spatial pattern pathway has SLC51A envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| SLC51A | GOBP_Transmembrane_Transport | Human | Brain | rep_1 | 2.8e-23 |
| SLC51A | GOBP_Transmembrane_Transport | Human | Liver | rep_1 | 1.0e-70 |
| SLC51A | GOBP_Organic_Hydroxy_Compound_Transport | Human | Intestine | A3 | 7.3e-09 |
| SLC51A | GOBP_Secretion | Human | Intestine | A3 | 1.8e-13 |
| SLC51A | GOBP_Transmembrane_Transport | Human | Intestine | A3 | 1.4e-10 |
| SLC51A | GOBP_Acid_Secretion | Human | Intestine | A8 | 1.6e-15 |
| SLC51A | GOBP_Bile_Acid_Secretion | Human | Intestine | A8 | 5.8e-11 |
| SLC51A | GOBP_Carboxylic_Acid_Transport | Human | Intestine | A8 | 4.8e-16 |
| SLC51A | GOBP_Lipid_Localization | Human | Intestine | A8 | 2.5e-15 |
| SLC51A | GOBP_Monocarboxylic_Acid_Transport | Human | Intestine | A8 | 7.2e-16 |
| SLC51A | GOBP_Organic_Acid_Transport | Human | Intestine | A8 | 1.5e-15 |
| SLC51A | GOBP_Organic_Anion_Transport | Human | Intestine | A8 | 3.5e-15 |
| SLC51A | GOBP_Acid_Secretion | Human | Uterus | rep_25 | 2.6e-11 |
| SLC51A | GOBP_Bile_Acid_And_Bile_Salt_Transport | Human | Uterus | rep_25 | 3.7e-10 |
| SLC51A | GOBP_Carboxylic_Acid_Transport | Human | Uterus | rep_26 | 9.1e-08 |
| SLC51A | GOBP_Lipid_Localization | Human | Uterus | rep_26 | 3.7e-10 |
| SLC51A | GOBP_Organic_Hydroxy_Compound_Transport | Human | Uterus | rep_29 | 3.2e-06 |
| SLC51A | GOBP_Organic_Hydroxy_Compound_Transport | Human | Breast | rep_1 | 9.0e-228 |
| SLC51A | GOBP_Secretion | Human | Breast | rep_1 | 9.7e-57 |
| SLC51A | GOBP_Transmembrane_Transport | Human | Breast | rep_1 | 3.2e-56 |
| SLC51A | GOBP_Bile_Acid_And_Bile_Salt_Transport | Human | Breast | rep_5 | 2.7e-05 |
| SLC51A | GOBP_Carboxylic_Acid_Transport | Human | Breast | rep_5 | 5.4e-12 |
| SLC51A | GOBP_Lipid_Localization | Human | Breast | rep_5 | 1.4e-06 |
| SLC51A | GOBP_Organic_Anion_Transport | Human | Breast | rep_5 | 9.5e-10 |
| SLC51A | GOBP_Acid_Secretion | Human | Breast | rep_6 | 1.6e-14 |
| SLC51A | GOBP_Bile_Acid_Secretion | Human | Breast | rep_6 | 1.2e-18 |
| SLC51A | GOBP_Monocarboxylic_Acid_Transport | Human | Breast | rep_6 | 1.9e-12 |
| SLC51A | GOBP_Organic_Acid_Transport | Human | Breast | rep_6 | 9.3e-09 |
| SLC51A | GOBP_Carboxylic_Acid_Transport | Human | Skin | P5_rep1 | 3.2e-08 |
| SLC51A | GOBP_Bile_Acid_And_Bile_Salt_Transport | Human | Skin | P10_rep1 | 1.2e-12 |
| SLC51A | GOBP_Acid_Secretion | Human | Skin | P10_rep2 | 4.9e-09 |
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SLC51A function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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SLC51A function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for SLC51A envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for SLC51A |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SLC51A |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| SLC51A | C0008370 | Cholestasis | 2 | CTD_human |
| SLC51A | C0008312 | Primary biliary cirrhosis | 1 | CTD_human |
| SLC51A | C0009241 | Cognition Disorders | 1 | CTD_human |
| SLC51A | C0023892 | Biliary cirrhosis | 1 | CTD_human |
| SLC51A | C0238065 | Secondary Biliary Cholangitis | 1 | CTD_human |
| SLC51A | C0342257 | Complications of Diabetes Mellitus | 1 | CTD_human |
| SLC51A | C4551595 | Biliary Cirrhosis, Primary, 1 | 1 | CTD_human |
