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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: LIPH (spascer ID:200879)

Gene summary for LIPH

Gene summary

Gene information
	Species	Human
	Gene symbol	LIPH
	Gene ID	200879
	Gene name	lipase H
	Synonyms	AH\|ARWH2\|HYPT7\|LAH2\|LPDLR\|PLA1B\|mPA-PLA1
	Cytomap	3q27.2
	Type of gene	protein-coding
	Description	lipase member HLPD lipase-related proteinlipase, member HmPA-PLA1 alphamembrane-associated phosphatidic acid-selective phospholipase A1-alphamembrane-bound phosphatidic acid-selective phospholipase A1phospholipase A(1)phospholipase A1 member B
	Modification date	20220513
	UniProtAcc	Q8WWY8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
LIPH	GO:0004465	lipoprotein lipase activity	21873635	Function
LIPH	GO:0004620	phospholipase activity	21873635	Function
LIPH	GO:0005615	extracellular space	21873635	Component
LIPH	GO:0006633	fatty acid biosynthetic process	21873635	Process
LIPH	GO:0016042	lipid catabolic process	21873635	Process
LIPH	GO:0016298	lipase activity	21873635	Function
LIPH	GO:0019433	triglyceride catabolic process	21873635	Process

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Spatial pattern events for LIPH

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
LIPH	Human	Prostate	rep_7	29925878	3.58e-12
LIPH	Human	Intestine	rep_colon1	34417225	1.95e-15
LIPH	Human	Intestine	rep_colon4	34417225	1.14e-15
LIPH	Human	Liver	rep_liver1	34417225	1.08e-15
LIPH	Human	Intestine	A1	33406409	2.09e-15
LIPH	Human	Intestine	A2	33406409	2.47e-15
LIPH	Human	Pancreas	PDAC-A-st1	31932730	3.68e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Intestine_A1_H&E
Intestine_A2_H&E

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Spatial pattern pathway has LIPH envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
LIPH	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
LIPH	GOBP_Organophosphate_Biosynthetic_Process	Human	Bladder	rep_4	3.2e-09
LIPH	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
LIPH	GOBP_Glycerophospholipid_Metabolic_Process	Human	Intestine	A3	7.7e-12
LIPH	GOBP_Lipid_Biosynthetic_Process	Human	Intestine	A3	5.0e-07
LIPH	GOBP_Organophosphate_Biosynthetic_Process	Human	Intestine	A3	2.2e-07
LIPH	GOBP_Organophosphate_Metabolic_Process	Human	Intestine	A3	4.4e-13
LIPH	GOBP_Phospholipid_Metabolic_Process	Human	Intestine	A3	3.0e-11
LIPH	GOBP_Cellular_Lipid_Metabolic_Process	Human	Intestine	A8	3.8e-13
LIPH	GOBP_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-13
LIPH	GOBP_Glycerolipid_Biosynthetic_Process	Human	Intestine	A8	1.4e-11
LIPH	GOBP_Glycerolipid_Metabolic_Process	Human	Intestine	A8	1.2e-09
LIPH	GOBP_Lipid_Catabolic_Process	Human	Intestine	A8	3.2e-08
LIPH	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
LIPH	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
LIPH	GOBP_Organic_Acid_Biosynthetic_Process	Human	Intestine	A8	2.1e-08
LIPH	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
LIPH	GOBP_Phosphatidic_Acid_Metabolic_Process	Human	Intestine	A8	1.9e-10
LIPH	GOBP_Phospholipid_Biosynthetic_Process	Human	Intestine	A8	2.2e-17
LIPH	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
LIPH	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
LIPH	GOBP_Neutral_Lipid_Catabolic_Process	Human	Pancreas	PDAC-A-st2	1.5e-05
LIPH	GOBP_Cellular_Lipid_Catabolic_Process	Human	Uterus	rep_26	4.6e-06
LIPH	GOBP_Fatty_Acid_Biosynthetic_Process	Human	Uterus	rep_26	9.2e-10
LIPH	GOBP_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
LIPH	GOBP_Glycerolipid_Biosynthetic_Process	Human	Uterus	rep_26	9.1e-06
LIPH	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	1.0e-07
LIPH	GOBP_Organic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	2.3e-06
LIPH	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
LIPH	GOBP_Organophosphate_Biosynthetic_Process	Human	Uterus	rep_26	8.0e-07
LIPH	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
LIPH	GOBP_Glycerolipid_Catabolic_Process	Human	Uterus	rep_29	1.7e-10
LIPH	GOBP_Glycerolipid_Metabolic_Process	Human	Uterus	rep_29	5.7e-07
LIPH	GOBP_Neutral_Lipid_Metabolic_Process	Human	Uterus	rep_29	2.0e-09
LIPH	GOBP_Phospholipid_Biosynthetic_Process	Human	Uterus	rep_29	6.7e-09
LIPH	GOBP_Triglyceride_Catabolic_Process	Human	Uterus	rep_29	7.0e-06
LIPH	GOBP_Triglyceride_Metabolic_Process	Human	Uterus	rep_29	1.9e-07
LIPH	GOBP_Glycerolipid_Biosynthetic_Process	Human	Breast	rep_1	2.0e-10
LIPH	GOBP_Neutral_Lipid_Catabolic_Process	Human	Breast	rep_1	4.6e-06
LIPH	GOBP_Neutral_Lipid_Metabolic_Process	Human	Breast	rep_1	3.3e-15
LIPH	GOBP_Organophosphate_Biosynthetic_Process	Human	Breast	rep_1	1.4e-07
LIPH	GOBP_Triglyceride_Catabolic_Process	Human	Breast	rep_1	3.5e-18
LIPH	GOBP_Triglyceride_Metabolic_Process	Human	Breast	rep_1	2.4e-04
LIPH	GOBP_Cellular_Lipid_Metabolic_Process	Human	Breast	rep_5	2.6e-07
LIPH	GOBP_Fatty_Acid_Biosynthetic_Process	Human	Breast	rep_5	2.8e-12
LIPH	GOBP_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	1.2e-06
LIPH	GOBP_Lipid_Biosynthetic_Process	Human	Breast	rep_5	7.0e-04
LIPH	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
LIPH	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Breast	rep_5	2.9e-17
LIPH	GOBP_Organic_Acid_Biosynthetic_Process	Human	Breast	rep_5	3.5e-09
LIPH	GOBP_Cellular_Lipid_Catabolic_Process	Human	Breast	rep_6	3.6e-11
LIPH	GOBP_Glycerolipid_Catabolic_Process	Human	Breast	rep_6	1.2e-11
LIPH	GOBP_Glycerolipid_Metabolic_Process	Human	Breast	rep_6	9.2e-09
LIPH	GOBP_Glycerophospholipid_Metabolic_Process	Human	Breast	rep_6	3.2e-05
LIPH	GOBP_Lipid_Catabolic_Process	Human	Breast	rep_6	2.9e-05
LIPH	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
LIPH	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
LIPH	GOBP_Organophosphate_Metabolic_Process	Human	Breast	rep_6	1.0e-12
LIPH	GOBP_Phosphatidic_Acid_Metabolic_Process	Human	Breast	rep_6	6.6e-08
LIPH	GOBP_Phospholipid_Biosynthetic_Process	Human	Breast	rep_6	5.0e-10
LIPH	GOBP_Phospholipid_Metabolic_Process	Human	Breast	rep_6	4.1e-09
LIPH	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
LIPH	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
LIPH	GOBP_Triglyceride_Catabolic_Process	Human	Skin	P2_rep2	3.3e-12
LIPH	GOBP_Triglyceride_Catabolic_Process	Human	Lung	rep_1	4.3e-10
LIPH	GOBP_Fatty_Acid_Biosynthetic_Process	Human	Lung	rep_2	7.8e-07
LIPH	GOBP_Glycerolipid_Catabolic_Process	Human	Lung	rep_2	8.6e-08
LIPH	GOBP_Lipid_Catabolic_Process	Human	Lung	rep_2	1.4e-09
LIPH	GOBP_Neutral_Lipid_Metabolic_Process	Human	Lung	rep_2	2.7e-09

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LIPH function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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LIPH function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for LIPH envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for LIPH

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for LIPH

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
LIPH	C1836672	Total Hypotrichosis, Mari type	3	GENOMICS_ENGLAND;UNIPROT
LIPH	C0345427	Woolly hair, congenital	2	CTD_human;ORPHANET
LIPH	C0020678	Hypotrichosis	1	CTD_human
LIPH	C0343073	Wooly hair	1	ORPHANET
LIPH	C1854310	Hypotrichosis simplex	1	ORPHANET